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SaveShare Save Share Save The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir (vol 15, pg e00465, 2024)
Dinh, Tung; Tber, Zahira; Rey, Juan S.; Mengshetti, Seema; Annamalai, Arun S.; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R.; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F.; Perilla, Juan R.; Kim, Baek; Kvaratskhelia, Mamuka Share Save Share Save Share Save The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravirDinh, Tung; Tber, Zahira; Rey, Juan S.; Mengshetti, Seema; Annamalai, Arun S.; Haney, Reed; Briganti, Lorenzo; Amblard, Franck; Fuchs, James R.; Cherepanov, Peter; Kim, Kyungjin; Schinazi, Raymond F.; Perilla, Juan R.; Kim, Baek; Kvaratskhelia, Mamuka Share Save Acetylation of SAMHD1 at lysine 580 is crucial for blocking HIV-1 infectionBulnes-Ramos, Angel; Schott, Kerstin; Rabinowitz, Jesse; Luchsinger, Charlotte; Bertelli, Cinzia; Miyagi, Eri; Yu, Corey H.; Persaud, Mirjana; Shepard, Caitlin; Koenig, Renate; Kim, Baek; Ivanov, Dmitri N.; Strebel, Klaus; Diaz-Griffero, Felipe Share Save The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activityPrasad, Chandra Bhushan; Oo, Adrian; Liu, Yujie; Qiu, Zhaojun; Zhong, Yaogang; Li, Na; Singh, Deepika; Xin, Xiwen; Cho, Young-Jae; Li, Zaibo; Zhang, Xiaoli; Yan, Chunhong; Zheng, Qingfei; Wang, Qi-En; Guo, Deliang; Kim, Baek; Zhang, Junran Share Save NSD2 overexpression drives multiple myeloma dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenomeSobh, Amin; Encinas, Elena; Patel, Alisha; Surapaneni, Greeshma; Kaestner, Charlotte; Poullard, Janai; Clerio, Monica; Vasan, Karthik; Freeman, Tzipporah; Lv, Dongwen; Dupere-Richer, Daphne; Riva, Alberto; Barwick, Benjamin; Zhou, Daohong; Boise, Lawrence; Mitsiades, Constantine; Kim, Baek; Bennett, Richard; Chandel, Navdeep; Licht, Jonathan Share Save SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patientsDaddacha, Waaqo; Monroe, Dominique; Schlafstein, Ashley J.; Withers, Allison E.; Thompson, Elizabeth B.; Danelia, Diana; Luong, Nho C.; Sesay, Fatmata; Rath, Sandip K.; Usoro, Edidiong R.; Essien, Mark E.; Jung, Andrew T.; Jiang, Jinmeng G.; Hu, Jiaxuan; Mahboubi, Bijan; Williams, Arilyn; Steinbeck, Julia E.; Yang, Xiaofeng; Buchwald, Zachary S.; Dynan, William S.; Switchenko, Jeffrey M.; Kim, Baek; Khan, Mohammad K.; Jaye, David L.; Yu, David S. Share Save The thioredoxin system determines CHK1 inhibitor sensitivity via redoxmediated regulation of ribonucleotide reductase activityPrasad, Chandra Bhushan; Oo, Adrian; Qiu, Zhaojun; Li, Na; Singh, Deepika; Xin, Xiwen; Cho, Young-Jae; Li, Zaibo; Zhang, Xiaoli; Yan, Chunhong; Zheng, Qingfei; Shao, Jimin; Wang, Qi-En; Kim, Baek; Zhang, Junran Share Save Removal of innate immune barriers allows efficient transduction of quiescent human hematopoietic stem cellsValeri, Erika; Unali, Giulia; Piras, Francesco; Abou-Alezz, Monah; Pais, Giulia; Benedicenti, Fabrizio; Lidonnici, Maria Rosa; Cuccovillo, Ivan; Castiglioni, Ilaria; Arevalo, Sergio; Spinozzi, Giulio; Merelli, Ivan; Behrendt, Rayk; Oo, Adrian; Kim, Baek; Landau, Nathaniel R.; Ferrari, Giuliana; Montini, Eugenio; Kajaste-Rudnitski, Anna Share Save Light-strand bias and enriched zones of embedded ribonucleotides are associated with DNA replication and transcription in the human-mitochondrial genomeXu, Penghao; Yang, Taehwan; Kundnani, Deepali L.; Sun, Mo; Marsili, Stefania; Gombolay, Alli L.; Jeon, Youngkyu; Newnam, Gary; Balachander, Sathya; Bazzani, Veronica; Baccarani, Umberto; Park, Vivian S.; Tao, Sijia; Lori, Adriana; Schinazi, Raymond F.; Kim, Baek; Pursell, Zachary F.; Tell, Gianluca; Vascotto, Carlo; Storici, Francesca Share Save Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1restriction,andcellulardNTPlevelsHIV-1 restriction, and cellular dNTP levelsSchussler, Moritz; Schott, Kerstin; Fuchs, Nina Verena; Oo, Adrian; Zahadi, Morssal; Rauch, Paula; Kim, Baek; Konig, Renate Share Save Biochemical functions and structure of Caenorhabditis elegans ZK177.8 protein: Aicardi-Goutières syndrome SAMHD1 dNTPase orthologMaehigashi, Tatsuya; Lim, Christopher; Wade, Lydia R.; Bowen, Nicole E.; Knecht, Kirsten M.; Alvarez, Natalie N.; Kelly, William G.; Schinazi, Raymond F.; Kim, Dong-Hyun; Xiong, Yong; Kim, Baek Share Save Share Save ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustionMenolfi, Demis; Lee, Brian J.; Zhang, Hanwen; Jiang, Wenxia; Bowen, Nicole E.; Wang, Yunyue; Zhao, Junfei; Holmes, Antony; Gershik, Steven; Rabadan, Raul; Kim, Baek; Zha, Shan Share Save NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancerReddy, Tejaswini P.; Puri, Akshjot; Guzman-Rojas, Liliana; Thomas, Christoforos; Qian, Wei; Zhou, Jianying; Zhao, Hong; Li, Xiaoxian; Mahboubi, Bijan; Oo, Adrian; Young-Jae, Cho; Kim, Baek; Thaiparambil, Jose; Chervo, Maria Florencia; Rosato, Roberto; Ayerbe, Camila; Giese, Noah; Moulder, Stacy; Piwnica-Worms, Helen; Meric-Bernstam, Funda; Chang, Jenny C. Share Save NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancerReddy, Tejaswini; Puri, Akshjot; Guzman, Liliana; Qian, Wei; Zhou, Jianying; Rosato, Roberto; Zhao, Hong; Thomas, Christoforos; Li, Xiaoxian; Mahboubi, Bijan; Oo, Adrian; Cho, Young-Jae; Kim, Baek; Thaiparambil, Jose; Ayerbe, Camila; Giese, Noah; Moulder, Stacy; Piwnica-Worms, Helen; Meric-Bernstam, Funda; Chang, Jenny Share Save 
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