Richard G. Vile - Publications, H-index & Citations

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Richard G. Vile

mayo clinic

77H-index

523Paper Count

1.8WCitation Count

Published Papers 156

Publication Date

Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity

Science Advances

IF12.5

2026-06-05

OAAI

Olivia Liseth; Elizabeth Appleton; Benjamin Kendall; Jill Thompson; Thanich Sangsuwannukul; Jason Tonne; Rosa Maria Diaz; Laura Evgin; Anton Patrikeev; Nicolas Sarbia; Shane Foo; Kevin Harrington; Masahiro Ono; Alan Melcher; Richard Vile

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Retinopathy caused by a primary immune regulatory disorder - the spectrum of AIRE-associated retinopathy: case series and literature review

Eye

IF3.2

2026-04-09

OAAI

Mohammad Anas; Andrew C. Browning; Siying Lin; Omar A. Mahroo; Andrew R. Webster; Margaret Reynolds; Tatyana Milman; Ralph C. Eagle; Richard Vile; Marc Toso; Gregory S. Hageman; Hossein Nazari; Erik J. Van Kuijk; Jose S. Pulido

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The TCR in CAR T cell therapy: use it or lose it?

Cancer Gene Therapy

IF5

2026-03-24

OAAI

Olivia Liseth; Richard Vile

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Using oncolytic viruses to exploit endogenous TCR signaling for modulation of CAR T phenotype and function against solid tumors

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Liseth, Olivia; Appleton, Elizabeth; Thompson, Jill; Kendall, Luke; Evgin, Laura; Ono, Masahiro; Melcher, Alan; Vile, Richard

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Novel immunocytokine CD80/IL2v synergizes with α-PD-1 for treatment of preclinical murine glioblastoma models

NEURO-ONCOLOGY

IF13.4

2025-11-01

OAAI

Owens, Carley; Jin, Fang; Seady, Marina Pedra; Maynes, Mark; Tritz, Zachariah; Ayasoufi, Katayoun; Parney, Ian; Hansen, Michael; Vile, Richard; Jang, Myoung Ho; Yun, Nari; Campian, Jian; Johnson, Aaron

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Oncolytic viruses as anticancer agents: clinical progress and remaining challenges

lancet

IF0

2025-09-18

PREAI

Elizabeth Appleton; E Antonio Chiocca; Guy Ungerechts; Alan Melcher; Richard Vile

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The progressively exhausted T cell response to a poorly immunogenic model of HCC can be partially rescued by immune checkpoint blockade and is heavily suppressed by T cell responses to oncolytic virotherapy

Molecular Therapy

IF12

2025-09-01

PREAI

Thanich Sangsuwannukul; Benjamin Kendall; Jason Tonne; Olivia Liseth; Jill Thompson; Kamonlapat Supimon; Muriel M. Metko; Alex Chen; Maria P. Chiriboga Yerovi; Rosa Maria Diaz; Laura Evgin; Mason J. Webb; Jacob van Vloten; Satdarshan P. Monga; Sheeba Irshad; Mark McNiven; Lewis Roberts; Richard G. Vile

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Exploiting Viral Infection/Vaccination To Focus High Affinity T Cell Populations into Tumors Using Oncolytic Viro-immunotherapy

Molecular Therapy

IF12

2025-08-20

OAAI

Alexa Veliz Rios; Muriel Metko; Jason Tonne; Jill Thompson; Benjamin Kendall; Alex Chen; Haley Mudrick; David Masopust; Sheeba Irshad; Mary Barry; Michael A. Barry; Rosa Maria Diaz; Richard Vile

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Author Correction: Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion

Nature Communications

IF15.7

2025-07-15

OAAI

Victoria Roulstone; Joan Kyula-Currie; James Wright; Emmanuel C. Patin; Isaac Dean; Lu Yu; Aida Barreiro-Alonso; Miriam Melake; Jyoti Choudhary; Richard Elliott; Christopher J. Lord; David Mansfield; Nik Matthews; Ritika Chauhan; Victoria Jennings; Charleen Chan Wah Hak; Holly Baldock; Francesca Butera; Elizabeth Appleton; Pablo Nenclares; Malin Pedersen; Shane Foo; Amarin Wongariyapak; Antonio Rullan; Tencho Tenev; Pascal Meier; Richard Vile; Hardev Pandha; Alan Melcher; Martin McLaughlin; Kevin J. Harrington

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Intranasal Prime-Boost with Spike Vectors Generates Antibody and T-Cell Responses at the Site of SARS-CoV-2 Infection

VACCINES

IF3.4

2024-10-18

OAAI

Metko, Muriel; Tonne, Jason; Rios, Alexa Veliz; Thompson, Jill; Mudrick, Haley; Masopust, David; Diaz, Rosa Maria; Barry, Michael A.; Vile, Richard G.

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Expression of tumor antigens within an oncolytic virus enhances the anti-tumor T cell response

NATURE COMMUNICATIONS

IF15.7

2024-06-27

OAAI

Webb, Mason J.; Sangsuwannukul, Thanich; van Vloten, Jacob; Evgin, Laura; Kendall, Benjamin; Tonne, Jason; Thompson, Jill; Metko, Muriel; Moore, Madelyn; Yerovi, Maria P. Chiriboga; Olin, Michael; Borgatti, Antonella; McNiven, Mark; Monga, Satdarshan P. S.; Borad, Mitesh J.; Melcher, Alan; Roberts, Lewis R.; Vile, Richard

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Activation of APOBEC3B in Self-Inactivating Lentiviral-Based CAR T Cell Production Increases the Mutational Load and Decreases the Killing Efficiency of CAR T Cells

JOURNAL OF IMMUNOLOGY

IF3.4

2024-05-01

PREAI

Swanson, Jack; Tonne, Jason; Vile, Richard

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A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-10-31

OAAI

Smith, Katherine E. R.; Peng, Kah-Whye; Pulido, Jose S.; Weisbrod, Adam J.; Strand, Carrie A.; Allred, Jacob B.; Newsom, Alysha N.; Zhang, Lianwen; Packiriswamy, Nandakumar; Kottke, Timothy; Tonne, Jason M.; Moore, Madelyn; Montane, Heather N.; Kottschade, Lisa A.; McWilliams, Robert R.; Dudek, Arkadiusz Z.; Yan, Yiyi; Dimou, Anastasios; Markovic, Svetomir N.; Federspiel, Mark J.; Vile, Richard G.; Dronca, Roxana S.; Block, Matthew S.

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Trap and ambush therapy using sequential primary and tumor escape-selective oncolytic viruses

MOLECULAR THERAPY ONCOLYTICS

IF5.3

2023-06-01

OAAI

Webb, Mason J.; Kottke, Timothy; Kendall, Benjamin L.; Swanson, Jack; Uzendu, Chisom; Tonne, Jason; Thompson, Jill; Metko, Muriel; Moore, Madelyn; Borad, Mitesh; Roberts, Lewis; Diaz, Rosa M.; Olin, Michael; Borgatti, Antonella; Vile, Richard

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Oncolytic viruses: Narcissistic or altruistic arsonists?

MOLECULAR THERAPY ONCOLYTICS

IF5.3

2023-06-01

OAAI

Kendall, Luke; Vile, Richard G.

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Current Status and Challenges of Oncolytic Virotherapy for the Treatment of Glioblastoma

PHARMACEUTICALS

IF4.8

2023-05-26

OAAI

Webb, Mason J.; Sener, Ugur; Vile, Richard G.

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Phase I trial of vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 (VSV-IFNb-TYRP1) in metastatic ocular melanoma

CANCER RESEARCH

IF16.6

2023-04-14

PREAI

Smith, Katherine E.; Weisbrod, Adam; Strand, Carrie; Allerd, Jacob; Pulido, Jose S.; Newsom, Alysha; Zhang, Lianwen; Packiriswamy, Nandakumar; Montane, Heather; Kottschade, Lisa; Dimou, Anastasios; Yan, Yiyi; Svetomir, Markovic; Peng, Kah Whye; Vile, Richard G.; Block, Matthew S.; Dronca, Roxana S.

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Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells

SCIENCE IMMUNOLOGY

IF16.3

2022-12-16

OAAI

Kunzli, Marco; O'Flanagan, Stephen D.; LaRue, Madeleine; Talukder, Poulami; Dileepan, Thamotharampillai; Stolley, J. Michael; Soerens, Andrew G.; Quarnstrom, Clare F.; Wijeyesinghe, Sathi; Ye, Yanqi; McPartlan, Justine S.; Mitchell, Jason S.; Mandl, Christian W.; Vile, Richard; Jenkins, Marc K.; Ahmed, Rafi; Vezys, Vaiva; Chahal, Jasdave S.; Masopust, David

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Phase I trial of sargramostim/pelareorep therapy in pediatric patients with recurrent or refractory high-grade brain tumors

NEURO-ONCOLOGY ADVANCES

IF4.1

2022-06-17

OAAI

Schuelke, Matthew R.; Gundelach, Justin H.; Coffey, Matt; West, Emma; Scott, Karen; Johnson, Derek R.; Samson, Adel; Melcher, Alan; Vile, Richard G.; Bram, Richard J.

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Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-04-13

111

OAAI

Evgin, Laura; Kottke, Tim; Tonne, Jason; Thompson, Jill; Huff, Amanda L.; van Vloten, Jacob; Moore, Madelyn; Michael, Josefine; Driscoll, Christopher; Pulido, Jose; Swanson, Eric; Kennedy, Richard; Coffey, Matt; Loghmani, Houra; Sanchez-Perez, Luis; Olivier, Gloria; Harrington, Kevin; Pandha, Hardev; Melcher, Alan; Diaz, Rosa Maria; Vile, Richard G.

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Research Directions