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Value of Multiomics Over Clinical Risk Factors in Hypertension Prediction Vuori, Matti; Ruuskanen, Matti O.; Jousilahti, Pekka; Salomaa, Veikko; Yeo, Li-Fang; Kauko, Anni; Vaura, Felix; Havulinna, Aki; Liu, Yang; Meric, Guillaume; Inouye, Michael; Knight, Rob; Lahti, Leo; Niiranen, Teemu Share Save
Combined clinical, metabolomic, and polygenic scores for cardiovascular risk prediction Ritchie, Scott C.; Jiang, Xilin; Pennells, Lisa; Xu, Yu; Coffey, Claire; Liu, Yang; Gibson, Joel T.; Surendran, Praveen; Karthikeyan, Savita; Lambert, Samuel A.; Danesh, John; Butterworth, Adam S.; Wood, Angela; Kaptoge, Stephen; Di Angelantonio, Emanuele; Inouye, Michael Share Save
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Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery disease Foguet, Carles; Jiang, Xilin; Ritchie, Scott C.; Persyn, Elodie; Xu, Yu; Ben-Eghan, Chief; Taylor, Henry J.; Di Angelantonio, Emanuele; Danesh, John; Butterworth, Adam S.; Lambert, Samuel A.; Inouye, Michael Share Save
Mitochondrial damage in muscle specific PolG mutant mice activates the integrated stress response and disrupts the mitochondrial folate cycle Bond, Simon T.; King, Emily J.; Walker, Shannen M.; Yang, Christine; Liu, Yingying; Liu, Kevin H.; Zhuang, Aowen; Jurrjens, Aaron W.; Fang, Haoyun A.; Formosa, Luke E.; Nath, Artika P.; Carmona, Sergio Ruiz; Inouye, Michael; Duong, Thy; Huynh, Kevin; Meikle, Peter J.; Crawford, Simon; Ramm, Georg; Elahee Doomun, Sheik Nadeem; de Souza, David P.; Rudler, Danielle L.; Calkin, Anna C.; Filipovska, Aleksandra; Greening, David W.; Henstridge, Darren C.; Drew, Brian G. Share Save
Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification D'Aoust, T; Clocchiatti-Tuozzo, S; Rivier, CA; Mishra, A; Hachiya, T; Grenier-Boley, B; Soumare, A; Duperron, MG; Le Grand, Q; Bouteloup, V; Proust-Lima, C; Samieri, C; Neuffer, J; Sargurupremraj, M; Chene, G; Helmer, C; Thibault, M; Amouyel, P; Lambert, JC; Kamatani, Y; Jacqmin-Gadda, H; Tregouet, DA; Inouye, M; Dufouil, C; Falcone, GJ; Debette, S Share Save
SARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx Martino, Cameron; Kellman, Benjamin P.; Sandoval, Daniel R.; Clausen, Thomas Mandel; Cooper, Robert; Benjdia, Alhosna; Soualmia, Feryel; Clark, Alex E.; Garretson, Aaron F.; Marotz, Clarisse A.; Song, Se Jin; Wandro, Stephen; Zaramela, Livia S.; Salido, Rodolfo A.; Zhu, Qiyun; Armingol, Erick; Vazquez-Baeza, Yoshiki; Mcdonald, Daniel; Sorrentino, James T.; Taylor, Bryn; Belda-Ferre, Pedro; Das, Promi; Ali, Farhana; Liang, Chenguang; Zhang, Yujie; Schifanella, Luca; Covizzi, Alice; Lai, Alessia; Riva, Agostino; Basting, Christopher; Broedlow, Courtney Ann; Havulinna, Aki S.; Jousilahti, Pekka; Estaki, Mehrbod; Kosciolek, Tomasz; Kuplicki, Rayus; Victor, Teresa A.; Paulus, Martin P.; Savage, Kristen E.; Benbow, Jennifer L.; Spielfogel, Emma S.; Anderson, Cheryl A. M.; Martinez, Maria Elena; Lacey, James V.; Huang, Shi; Haiminen, Niina; Parida, Laxmi; Kim, Ho-Cheol; Gilbert, Jack A.; Sweeney, Daniel A.; Allard, Sarah M.; Swafford, Austin D.; Cheng, Susan; Inouye, Michael; Niiranen, Teemu; Jain, Mohit; Salomaa, Veikko; Zengler, Karsten; Klatt, Nichole R.; Hasty, Jeff; Berteau, Olivier; Carlin, Aaron F.; Esko, Jeffrey D.; Lewis, Nathan E.; Knight, Rob Share Save
Polygenic Prediction of Recurrent Events After Early-Onset Myocardial Infarction Ardissino, Maddalena; Paraboschi, Elvezia Maria; Lambert, Samuel A.; Kim, Lois G.; Kelemen, Martin; Maglietta, Giuseppe; Crocamo, Antonio; Magnani, Giulia; Bricoli, Serena; Vignali, Luigi; Niccoli, Giampaolo; Tubaro, Marco; Pastika, Libor; Sau, Arunashis; Ng, Fu Siong; de Marvao, Antonio; Honigberg, Michael C.; Natarajan, Pradeep; Nelson, Adam J.; Inouye, Michael; Di Angelantonio, Emanuele; Asselta, Rosanna; Ardissino, Diego; Butterworth, Adam S. Share Save
Phylogeny-Aware Analysis of Metagenome Community Ecology Based on Matched Reference Genomes while Bypassing Taxonomy (vol 7, pg e00167, 2023) Zhu, Qiyun; Huang, Shi; Gonzalez, Antonio; Mcgrath, Imran; Mcdonald, Daniel; Haiminen, Niina; Armstrong, George; Vazquez-Baeza, Yoshiki; Yu, Julian; Kuczynski, Justin; Sepich-Poore, Gregory D.; Swafford, Austin D.; Das, Promi; Shaffer, Justin P.; Lejzerowicz, Franck; Belda-Ferre, Pedro; Havulinna, Aki S.; Meric, Guillaume; Niiranen, Teemu; Lahti, Leo; Salomaa, Veikko; Kim, Ho-Cheol; Jain, Mohit; Inouye, Michael; Gilbert, Jack A.; Knight, Rob Share Save
The NHGRI-EBI GWAS Catalog: standards for reusability, sustainability and diversity Cerezo, Maria; Sollis, Elliot; Ji, Yue; Lewis, Elizabeth; Abid, Ala; Bircan, Karatug Ozan; Hall, Peggy; Hayhurst, James; John, Sajo; Mosaku, Abayomi; Ramachandran, Santhi; Foreman, Amy; Ibrahim, Arwa; McLaughlin, James; Pendlington, Zoe; Stefancsik, Ray; Lambert, Samuel A.; McMahon, Aoife; Morales, Joannella; Keane, Thomas; Inouye, Michael; Parkinson, Helen; Harris, Laura W. Share Save
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Cardiovascular risk prediction using metabolomic biomarkers and polygenic risk scores: a cohort study and modelling analyses Ritchie, S.; Jiang, X.; Pennells, L.; Xu, Y.; Coffey, C.; Liu, Y.; Surendran, P.; Karthikeyan, S.; Lambert, S.; Danesh, J.; Butterworth, A.; Wood, A.; Kaptoge, S.; Di Angelantonio, E.; Inouye, M. Share Save
Genome-wide association testing beyond SNPs Harris, Laura; McDonagh, Ellen M.; Zhang, Xiaolei; Fawcett, Katherine; Foreman, Amy; Daneck, Petr; Sergouniotis, Panagiotis I.; Parkinson, Helen; Mazzarotto, Francesco; Inouye, Michael; Hollox, Edward J.; Birney, Ewan; Fitzgerald, Tomas Share Save
Enhancing the Polygenic Score Catalog with tools for score calculation and ancestry normalization Lambert, Samuel A.; Wingfield, Benjamin; Gibson, Joel T.; Gil, Laurent; Ramachandran, Santhi; Yvon, Florent; Saverimuttu, Shirin; Tinsley, Emily; Lewis, Elizabeth; Ritchie, Scott C.; Wu, Jingqin; Canovas, Rodrigo; McMahon, Aoife; Harris, Laura W.; Parkinson, Helen; Inouye, Michael Share Save
Evaluating the cost-effectiveness of polygenic risk score-stratified screening for abdominal aortic aneurysm Kelemen, M.; Danesh, J.; Di Angelantonio, E.; Inouye, M.; O'Sullivan, J.; Pennells, L.; Roychowdhury, T.; Sweeting, M. J.; Wood, A. M.; Harrison, S.; Kim, L. G. Share Save
Misexpression of inactive genes in whole blood is associated with nearby rare structural variants Vanderstichele, Thomas; Burnham, Katie L.; de Klein, Niek; Tardaguila, Manuel; Howell, Brittany; Walter, Klaudia; Kundu, Kousik; Koeppel, Jonas; Lee, Wanseon; Tokolyi, Alex; Persyn, Elodie; Nath, Artika P.; Marten, Jonathan; Petrovski, Slave; Roberts, David J.; Di Angelantonio, Emanuele; Danesh, John; Berton, Alix; Platt, Adam; Butterworth, Adam S.; Soranzo, Nicole; Parts, Leopold; Inouye, Michael; Paul, Dirk S.; Davenport, Emma E. Share Save
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Evaluation of polygenic scoring methods in five biobanks shows larger variation between biobanks than methods and finds benefits of ensemble learning Monti, Remo; Eick, Lisa; Hudjashov, Georgi; Lall, Kristi; Kanoni, Stavroula; Wolford, Brooke N.; Wingfield, Benjamin; Pain, Oliver; Wharrie, Sophie; Jermy, Bradley; McMahon, Aoife; Hartonen, Tuomo; Heyne, Henrike; Mars, Nina; Lambert, Samuel; Hveem, Kristian; Inouye, Michael; van Heel, David A.; Magi, Reedik; Marttinen, Pekka; Ripatti, Samuli; Ganna, Andrea; Lippert, Christoph Share Save
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