Not logged in Long-lasting B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins Guthmiller, Jenna J.; Lan, Linda Yu-Ling; Li, Lei; Fu, Yanbin; Nelson, Sean A.; Henry, Carole; Stamper, Christopher T.; Utset, Henry A.; Freyn, Alec W.; Han, Julianna; Stovicek, Olivia; Wang, Jiaolong; Zheng, Nai-Ying; Huang, Min; Dugan, Haley L.; Tepora, Micah E.; Zhu, Xueyong; Chen, Yao-Qing; Palm, Anna-Karin E.; Shaw, Dustin G.; Loganathan, Madhumathi; Francis, Benjamin F.; Sun, Jiayi; Chervin, Jordan; Troxell, Chloe; Meade, Philip; Leung, Nancy H. L.; Valkenburg, Sophie A.; Cobey, Sarah; Cowling, Benjamin J.; Wilson, Ian A.; Garcia-Sastre, Adolfo; Nachbagauer, Raffael; Ward, Andrew B.; Coughlan, Lynda; Krammer, Florian; Wilson, Patrick C. Share Save
Mpox mRNA-1769 vaccine inhibits orthopoxvirus replication at intranasal, intrarectal, and cutaneous sites of inoculation Cotter, Catherine A.; Ignacio, Maxinne A.; Americo, Jeffrey L.; Earl, Patricia L.; Mucker, Eric M.; Frey, Tiffany R.; Carfi, Andrea; Hooper, Jay W.; Freyn, Alec W.; Moss, Bernard Share Save
An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge Freyn, Alec W.; Atyeo, Caroline; Earl, Patricia L.; Americo, Jeffrey L.; Chuang, Gwo-Yu; Natarajan, Harini; Frey, Tiffany R.; Gall, Jason G.; Moliva, Juan I.; Hunegnaw, Ruth; Arunkumar, Guha Asthagiri; Ogega, Clinton O.; Nasir, Arshan; Santos, Genesis; Levin, Rafael H.; Meni, Anusha; Jorquera, Patricia A.; Bennett, Hamilton; Johnson, Joshua A.; Durney, Michael A.; Stewart-Jones, Guillaume; Hooper, Jay W.; Colpitts, Tonya M.; Alter, Galit; Sullivan, Nancy J.; Carfi, Andrea; Moss, Bernard Share Save
An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults Widge, Alicia T.; Hofstetter, Amelia R.; V. Houser, Katherine; Awan, Seemal F.; Chen, Grace L.; Florez, Maria C. Burgos; Berkowitz, Nina M.; Mendoza, Floreliz; Hendel, Cynthia S.; Holman, LaSonji A.; Gordon, Ingelise J.; Apte, Preeti; Liang, C. Jason; Gaudinski, Martin R.; Coates, Emily E.; Strom, Larisa; Wycuff, Diane; Vazquez, Sandra; Stein, Judy A.; Gall, Jason G.; Adams, William C.; Carlton, Kevin; Gillespie, Rebecca A.; Creanga, Adrian; Crank, Michelle C.; Andrews, Sarah F.; Castro, Mike; Serebryannyy, Leonid A.; Narpala, Sandeep R.; Hatcher, Christian; Lin, Bob C.; O'Connell, Sarah; Freyn, Alec W.; Rosado, Victoria C.; Nachbagauer, Raffael; Palese, Peter; Kanekiyo, Masaru; McDermott, Adrian B.; Koup, Richard A.; Dropulic, Lesia K.; Graham, Barney S.; Mascola, John R.; Ledgerwood, Julie E. Share Save
Altering the mRNA-1273 dosing interval impacts the kinetics, quality, and magnitude of immune responses in mice Garcia-Dominguez, Dario; Henry, Carole; Ma, LingZhi; Jani, Hardik; Amato, Nicholas J.; Manning, Taylor; Freyn, Alec; Davis, Heather; Hsiao, Chiaowen Joyce; Li, Mengying; Koch, Hillary; Elbashir, Sayda; DiPiazza, Anthony; Carfi, Andrea; Edwards, Darin; Bahl, Kapil Share Save
B cell convergence to distinct broadly reactive epitopes revealed by chimeric hemagglutinin vaccination Guthmiller, Jenna; Li, Lei; Lan, Linda Yu-Ling; Henry, Carole; Stamper, Christopher; Freyn, Alec; Utset, Henry; Han, Julianna; Palese, Peter; Coughlan, Lynda; Ward, Andrew; Krammer, Florian; Wilson, Patrick C. Share Save
A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice Bliss, Carly M.; Freyn, Alec W.; Caniels, Tom G.; Leyva-Grado, Victor H.; Nachbagauer, Raffael; Sun, Weina; Tan, Gene S.; Gillespie, Virginia L.; McMahon, Meagan; Krammer, Florian; Hill, Adrian V. S.; Palese, Peter; Coughlan, Lynda Share Save
Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial Houser, Katherine, V; Chen, Grace L.; Carter, Cristina; Crank, Michelle C.; Nguyen, Thuy A.; Florez, Maria Claudia Burgos; Berkowitz, Nina M.; Mendoza, Floreliz; Hendel, Cynthia Starr; Gordon, Ingelise J.; Coates, Emily E.; Vazquez, Sandra; Stein, Judy; Case, Christopher L.; Lawlor, Heather; Carlton, Kevin; Gaudinski, Martin R.; Strom, Larisa; Hofstetter, Amelia R.; Liang, C. Jason; Narpala, Sandeep; Hatcher, Christian; Gillespie, Rebecca A.; Creanga, Adrian; Kanekiyo, Masaru; Raab, Julie E.; Andrews, Sarah F.; Zhang, Yi; Yang, Eun Sung; Wang, Lingshu; Leung, Kwanyee; Kong, Wing-Pui; Freyn, Alec W.; Nachbagauer, Raffael; Palese, Peter; Bailer, Robert T.; McDermott, Adrian B.; Koup, Richard A.; Gall, Jason G.; Arnold, Frank; Mascola, John R.; Graham, Barney S.; Ledgerwood, Julie E. Share Save
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models Maisonnasse, Pauline; Aldon, Yoann; Marc, Aurelien; Marlin, Romain; Dereuddre-Bosquet, Nathalie; Kuzmina, Natalia A.; Freyn, Alec W.; Snitselaar, Jonne L.; Goncalves, Antonio; Caniels, Tom G.; Burger, Judith A.; Poniman, Meliawati; Bontjer, Ilja; Chesnais, Virginie; Diry, Segolene; Iershov, Anton; Ronk, Adam J.; Jangra, Sonia; Rathnasinghe, Raveen; Brouwer, Philip J. M.; Bijl, Tom P. L.; van Schooten, Jelle; Brinkkemper, Mitch; Liu, Hejun; Yuan, Meng; Mire, Chad E.; van Breemen, Marielle J.; Contreras, Vanessa; Naninck, Thibaut; Lemaitre, Julien; Kahlaoui, Nidhal; Relouzat, Francis; Chapon, Catherine; Fang, Raphael Ho Tsong; McDanal, Charlene; Osei-Twum, Mary; St-Amant, Natalie; Gagnon, Luc; Montefiori, David C.; Wilson, Ian A.; Ginoux, Eric; de Bree, Godelieve J.; Garcia-Sastre, Adolfo; Schotsaert, Michael; Coughlan, Lynda; Bukreyev, Alexander; van der Werf, Sylvie; Guedj, Jeremie; Sanders, Rogier W.; van Gils, Marit J.; Le Grand, Roger Share Save
First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes Guthmiller, Jenna J.; Han, Julianna; Li, Lei; Freyn, Alec W.; Liu, Sean T. H.; Stovicek, Olivia; Stamper, Christopher T.; Dugan, Haley L.; Tepora, Micah E.; Utset, Henry A.; Bitar, Dalia J.; Hamel, Natalie J.; Changrob, Siriruk; Zheng, Nai-Ying; Huang, Min; Krammer, Florian; Nachbagauer, Raffael; Palese, Peter; Ward, Andrew B.; Wilson, Patrick C. Share Save
Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes Freyn, Alec W.; Han, Julianna; Guthmiller, Jenna J.; Bailey, Mark J.; Neu, Karlynn; Turner, Hannah L.; Rosado, Victoria C.; Chromikova, Veronika; Huang, Min; Strohmeier, Shirin; Liu, Sean T. H.; Simon, Viviana; Krammer, Florian; Ward, Andrew B.; Palese, Peter; Wilson, Patrick C.; Nachbagauer, Raffael Share Save
CD4+ follicular regulatory T cells optimize the influenza virus-specific B cell response Lu, Yisi; Jiang, Roy; Freyn, Alec W.; Wang, Jiawei; Strohmeier, Shirin; Lederer, Katlyn; Locci, Michela; Zhao, Hongyu; Angeletti, Davide; O'Connor, Kevin C.; Kleinstein, Steven H.; Nachbagauer, Raffael; Craft, Joe Share Save
A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial Nachbagauer, Raffael; Feser, Jodi; Naficy, Abdollah; Bernstein, David, I; Guptill, Jeffrey; Walter, Emmanuel B.; Berlanda-Scorza, Franceso; Stadlbauer, Daniel; Wilson, Patrick C.; Aydillo, Teresa; Behzadi, Mohammad Amin; Bhavsar, Disha; Bliss, Carly; Capuano, Christina; Carreno, Juan Manuel; Chromikova, Veronika; Claeys, Carine; Coughlan, Lynda; Freyn, Alec W.; Gast, Christopher; Javier, Andres; Jiang, Kaijun; Mariottini, Chiara; McMahon, Meagan; McNeal, Monica; Solorzano, Alicia; Strohmeier, Shirin; Sun, Weina; Van der Wielen, Marie; Innis, Bruce L.; Garcia-Sastre, Adolfo; Palese, Peter; Krammer, Florian Share Save
Enhancing Neuraminidase Immunogenicity of Influenza A Viruses by Rewiring RNA Packaging Signals Zheng, Allen; Sun, Weina; Xiong, Xiaoli; Freyn, Alec W.; Peukes, Julia; Strohmeier, Shirin; Nachbagauer, Raffael; Briggs, John A. G.; Krammer, Florian; Palese, Peter Share Save
A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice Freyn, Alec W.; da Silva, Jamile Ramos; Rosado, Victoria C.; Bliss, Carly M.; Pine, Matthew; Mui, Barbara L.; Tam, Ying K.; Madden, Thomas D.; de Souza Ferreira, Luis Carlos; Weissman, Drew; Krammer, Florian; Coughlan, Lynda; Palese, Peter; Pardi, Norbert; Nachbagauer, Raffael Share Save
Synthetic Rhamnose Glycopolymer Cell-Surface Receptor for Endogenous Antibody Recruitment De Coen, Ruben; Nuhn, Lutz; Perera, Chamani; Arista-Romero, Maria; Risseeuw, Martijn D. P.; Freyn, Alec; Nachbagauer, Raffael; Albertazzi, Lorenzo; Van Calenbergh, Serge; Spiegel, David A.; Peterson, Blake R.; De Geest, Bruno G. Share Save
Human Monoclonal Antibodies Potently Neutralize Zika Virus and Select for Escape Mutations on the Lateral Ridge of the Envelope Protein Bailey, Mark J.; Broecker, Felix; Freyn, Alec W.; Choi, Angela; Brown, Julia A.; Fedorova, Nadia; Simon, Viviana; Lim, Jean K.; Evans, Matthew J.; Garcia-Sastre, Adolfo; Palese, Peter; Tan, Gene S. Share Save
Antigenic sites in influenza H1 hemagglutinin display species-specific immunodominance Liu, Sean T. H.; Behzadi, Mohammad Amin; Sun, Weina; Freyn, Alec W.; Liu, Wen-Chun; Broecker, Felix; Albrecht, Randy A.; Bouvier, Nicole M.; Simon, Viviana; Nachbagauer, Raffael; Krammer, Florian; Palese, Peter Share Save
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