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Nathan C. Sheffield

genome sciences

33H-index
153Paper Count
1.3WCitation Count
Published Papers 48
Publication Date
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Automated biomedical hypothesis generation with time-aware hypergraph contrastive learning
errKnowledge and Information Systems
IF3.1
err2026-05-17
err0
errOAAI
errAmir Hassan Shariatmadari; Sikun Guo; Nathan C. Sheffield; Aidong Zhang; Kishlay Jha
errShare
errSave
ConceptDrift: leveraging spatial, temporal and semantic evolution of biomedical concepts for hypothesis generation
errBIOINFORMATICS
IF5.4
err2025-11-01
err0
errOAAI
errShariatmadari, Amir Hassan; Jafari, Alireza; Guo, Sikun; Srinivasan, Sneha; Sheffield, Nathan C.; Zhang, Aidong; Jha, Kishlay
errShare
errSave
The reninness score: integrative analysis of multi-omic data to define renin cell identity.
errHYPERTENSION
IF8.2
err2024-09-01
err0
PREAI
errXue, Bingjie; Medrano, Silvia; Smith, Jason; Martini, Alexandre; Sequeira, Maria Luisa; Sheffield, Nathan; Gomez, Ariel
errShare
errSave
Inhibition of Renin Expression Is Regulated by an Epigenetic Switch From an Active to a Poised State
errHYPERTENSION
IF8.2
err2024-09-01
err1
PREAI
errSmith, Jason P.; Paxton, Robert; Medrano, Silvia; Sheffield, Nathan C.; Sequeira-Lopez, Maria Luisa S.; Gomez, R. Ariel
errShare
errSave
Methods for constructing and evaluating consensus genomic interval sets
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-08-24
err1
errOAAI
errRymuza, Julia; Sun, Yuchen; Zheng, Guangtao; LeRoy, Nathan J.; Murach, Maria; Phan, Neil; Zhang, Aidong; Sheffield, Nathan C.
errShare
errSave
Methods for evaluating unsupervised vector representations of genomic regions
errgenomics proteomics bioinformatics
IF2.8
err2024-08-10
err0
errOAAI
errZheng, Guangtao; Rymuza, Julia; Gharavi, Erfaneh; Leroy, Nathan J.; Zhang, Aidong; Sheffield, Nathan C.
errShare
errSave
PEPhub: a database, web interface, and API for editing, sharing, and validating biological sample metadata
errGIGASCIENCE
IF3.9
err2024-07-11
err0
errOAAI
errLeRoy, Nathan J.; Khoroshevskyi, Oleksandr; O'Brien, Aaron; Stepien, Rafal; Arslan, Alip; Sheffield, Nathan C.
errShare
errSave
Fast clustering and cell-type annotation of scATAC data using pre-trained embeddings
errgenomics proteomics bioinformatics
IF2.8
err2024-07-05
err2
errOAAI
errLeRoy, Nathan J.; Smith, Jason P.; Zheng, Guangtao; Rymuza, Julia; Gharavi, Erfaneh; Brown, Donald E.; Zhang, Aidong; Sheffield, Nathan C.
errShare
errSave
Joint Representation Learning for Retrieval and Annotation of Genomic Interval Sets
errBIOENGINEERING-BASEL
IF3.7
err2024-03-08
err3
errOAAI
errGharavi, Erfaneh; Leroy, Nathan J.; Zheng, Guangtao; Zhang, Aidong; Brown, Donald E.; Sheffield, Nathan C.
errShare
errSave
Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis
errCELL REPORTS
IF6.9
err2023-11-01
err15
errOAAI
errMosquera, Jose Verdezoto; Auguste, Gaelle; Wong, Doris; Turner, Adam W.; Hodonsky, Chani J.; Alvarez-Yela, Astrid Catalina; Song, Yipei; Cheng, Qi; Cardenas, Christian L. Lino; Theofilatos, Konstantinos; Bos, Maxime; Kavousi, Maryam; Peyser, Patricia A.; Mayr, Manuel; Kovacic, Jason C.; Bjorkegren, Johan L. M.; Malhotra, Rajeev; Stukenberg, P. Todd; Finn, Aloke, V; van der Laan, Sander W.; Zang, Chongzhi; Sheffield, Nathan C.; Miller, Clint L.
errShare
errSave
The Reninness Score: Integrative Analysis Of Multi-omic Data To Define Renin Cell Identity
errHYPERTENSION
IF8.2
err2023-09-01
err0
PREAI
errXue, Bingjie; Medrano, Silvia; Martini, Alexandre G.; Smith, Jason; Sheffield, Nathan; Gomez, Roberto A.; Lopez, Maria Luisa S. Sequeira
errShare
errSave
Renin Cell Development: Insights From Chromatin Accessibility and Single-Cell Transcriptomics
errCIRCULATION RESEARCH
IF16.2
err2023-08-04
err2
errOAAI
errMartini, Alexandre G.; Smith, Jason P.; Medrano, Silvia; Finer, Gal; Sheffield, Nathan C.; Sequeira-Lopez, Maria Luisa S.; Gomez, R. Ariel
errShare
errSave
Integrative Single-cell Meta-analysis Reveals Diseaserelevant Vascular Cell States and Markers in Human Atherosclerosis
errARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
err2023-05-01
err0
PREAI
errMosquera, Jose E. Verdezoto; Wong, Doris; Auguste, Gaelle; Turner, Adam; Hodonsky, Chani J.; Cardenas, Christian L. Lino; Theofilatos, Konstantinos; Bos, Maxime; Kavousi, Maryam; Peyser, Patricia R.; Mayr, Manuel; Kovacic, Jason; Bjorkegren, Johan; Malhotra, Rajeev; van der Laan, Sander; Zang, Chongzhi; Sheffield, Nathan; Miller, Clint
errShare
errSave
Specific Chromatin Configurations Across The Genome Determine The Renin Cell Identity
errHYPERTENSION
IF8.2
err2022-09-01
err0
PREAI
errXue, Bingjie; Medrano, Silvia; Smith, Jaosn; Martini, Alexandre G.; Sheffield, Nathan; Sequeira-Lopez, Maria Luisa; Gomez, Roberto A.
errShare
errSave
Epigenetic Determinants Of Renin Cell Identity
errHYPERTENSION
IF8.2
err2022-09-01
err0
PREAI
errSmith, Jason P.; Martini, Alexandre G.; Sheffield, Nathan; Lopez, Maria Sequeira; Gomez, Roberto A.
errShare
errSave
Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-06-22
err20
errOAAI
errDuvall, Eliza; Benitez, Cecil M.; Tellez, Krissie; Enge, Martin; Pauerstein, Philip T.; Li, Lingyu; Baek, Songjoon; Quake, Stephen R.; Smith, Jason P.; Sheffield, Nathan C.; Kim, Seung K.; Arda, H. Efsun
errShare
errSave
GenomicDistributions: fast analysis of genomic intervals with Bioconductor
errBMC GENOMICS
IF3.7
err2022-04-12
err6
errOAAI
errKupkova, Kristyna; Mosquera, Jose Verdezoto; Smith, Jason P.; Stolarczyk, Michal; Danehy, Tessa L.; Lawson, John T.; Xue, Bingjie; Stubbs, John T.; LeRoy, Nathan; Sheffield, Nathan C.
errShare
errSave
Detecting molecular subtypes from multi-omics datasets using SUMO
errCELL REPORTS METHODS
IF4.5
err2022-01-01
err10
errOAAI
errSienkiewicz, Karolina; Chen, Jinyu; Chatrath, Ajay; Lawson, John T.; Sheffield, Nathan C.; Zhang, Louxin; Ratan, Aakrosh
errShare
errSave
Linking big biomedical datasets to modular analysis with Portable Encapsulated Projects
errGIGASCIENCE
IF3.9
err2021-12-06
err6
errOAAI
errSheffield, Nathan C.; Stolarczyk, Michal; Reuter, Vincent P.; Rendeiro, Andre F.
errShare
errSave
PEPATAC: an optimized pipeline for ATAC-seq data analysis with serial alignments
errgenomics proteomics bioinformatics
IF2.8
err2021-11-23
err36
errOAAI
errSmith, Jason P.; Corces, M. Ryan; Xu, Jin; Reuter, Vincent P.; Chang, Howard Y.; Sheffield, Nathan C.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Steven J.M. Jones
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D
David Haussler
H-index: 175 · Papers: 720
P
Paul Flicek
H-index: 167 · Papers: 522
H
Howard Y. Chang
H-index: 162 · Papers: 736
A
ArmstrongNicola (Albert V. Smith)
H-index: 154 · Papers: 735
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