Not logged inGenetic Reduction of the Translational Repressors FMRP and 4E-BP2 Preserves Memory in Mouse Models of Alzheimer's Disease
Ribeiro, Felipe C.; Cozachenco, Danielle; Parkhill, Michael; Rodrigue, Brandon; Borges, Caio; Lacaille, Jean-Claude; Nader, Karim; De Felice, Fernanda G.; Lourenco, Mychael V.; Aguilar-Valles, Argel; Sonenberg, Nahum; Ferreira, Sergio T. .png)
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SaveKIBRA anchoring the action of PKMζ maintains the persistence of memoryTsokas, Panayiotis; Hsieh, Changchi; Flores-Obando, Rafael E.; Bernabo, Matteo; Tcherepanov, Andrew; Hernandez, A. Ivan; Thomas, Christian; Bergold, Peter J.; Cottrell, James E.; Kremerskothen, Joachim; Shouval, Harel Z.; Nader, Karim; Fenton, Andre A.; Sacktor, Todd C. Share Save The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's diseaseRibeiro, Felipe C.; Cozachenco, Danielle; Argyrousi, Elentina K.; Staniszewski, Agnieszka; Wiebe, Shane; Calixtro, Joao D.; Soares-Neto, Rubens; Al-Chami, Aycheh; El Sayegh, Fatema; Bermudez, Sara; Arsenault, Emily; Cossenza, Marcelo; Lacaille, Jean-Claude; Nader, Karim; Sun, Hongyu; De Felice, Fernanda G.; Lourenco, Mychael V.; Arancio, Ottavio; Aguilar-Valles, Argel; Sonenberg, Nahum; Ferreira, Sergio T. Share Save Share Save Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndromeHooshmandi, Mehdi; Sharma, Vijendra; Perez, Carolina Thorn; Sood, Rapita; Krimbacher, Konstanze; Wong, Calvin; Lister, Kevin C.; Guzman, Alba Urena; Bartley, Trevor D.; Rocha, Cecilia; Maussion, Gilles; Nadler, Emma; Roque, Patricia Margarita; Gantois, Ilse; Popic, Jelena; Levesque, Maxime; Kaufman, Randal J.; Avoli, Massimo; Sanz, Elisenda; Nader, Karim; Hagerman, Randi Jenssen; Durcan, Thomas M.; Costa-Mattioli, Mauro; Prager-Khoutorsky, Masha; Lacaille, Jean-Claude; Martinez-Cerdeno, Veronica; Gibson, Jay R.; Huber, Kimberly M.; Sonenberg, Nahum; Gkogkas, Christos G.; Khoutorsky, Arkady Share Save Share Save Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needsSaber, Sameh; Nasr, Mohamed; Kaddah, Mohamed M. Y.; Mostafa-Hedeab, Gomaa; Cavalu, Simona; Mourad, Ahmed A. E.; Gaafar, Ahmed Gaafar Ahmed; Zaghlool, Sameh S.; Saleh, Safaa; Hafez, Mohamed M.; Girgis, Samuel; Elgharabawy, Rehab Mohamed; Nader, Karim; Alsharidah, Mansour; Batiha, Gaber El-Saber; El-Ahwany, Eman; Amin, Noha A.; Elagamy, Heba, I; Shata, Ahmed; Nader, Reem; Khodir, Ahmed E. Share Save Share Save Share Save Share Save Share Save Telmisartan attenuates N-nitrosodiethylamine-induced hepatocellular carcinoma in mice by modulating the NF-κB-TAK1-ERK1/2 axis in the context of PPARγ agonistic activitySaber, Sameh; Khodir, Ahmed E.; Soliman, Wafaa E.; Salama, Mohamed M.; Abdo, Walied S.; Elsaeed, Baraah; Nader, Karim; Abdelnasser, Aya; Megahed, Nada; Basuony, Mohamed; Shawky, Ahmed; Mahmoud, Maryam; Medhat, Reham; Eldin, Abdelrahman S. Share Save Share Save Share Save Share Save Metformin ameliorates core deficits in a mouse model of fragile X syndromeGantois, Ilse; Khoutorsky, Arkady; Popic, Jelena; Aguilar-Valles, Argel; Freemantle, Erika; Cao, Ruifeng; Sharma, Vijendra; Pooters, Tine; Nagpal, Anmol; Skalecka, Agnieszka; Truong, Vinh T.; Wiebe, Shane; Groves, Isabelle A.; Jafarnejad, Seyed Mehdi; Chapat, Clement; McCullagh, Elizabeth A.; Gamache, Karine; Nader, Karim; Lacaille, Jean-Claude; Gkogkas, Christos G.; Sonenberg, Nahum Share Save Share Save Share Save Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like PhenotypesGkogkas, Christos G.; Khoutorsky, Arkady; Cao, Ruifeng; Jafarnejad, Seyed Mehdi; Prager-Khoutorsky, Masha; Giannakas, Nikolaos; Kaminari, Archontia; Fragkouli, Apostolia; Nader, Karim; Price, Theodore J.; Konicek, Bruce W.; Graff, Jeremy R.; Tzinia, Athina K.; Lacaille, Jean-Claude; Sonenberg, Nahum Share Save Share Save 
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