Not logged inOncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
Pastoors, Dorien; Havermans, Marije; Mulet-Lazaro, Roger; Brian, Duncan; Noort, Willy; Grasel, Julius; Hoogenboezem, Remco; Smeenk, Leonie; Demmers, Jeroen A. A.; Milsom, Michael D.; Enver, Tariq; Groen, Richard W. J.; Bindels, Eric; Delwel, Ruud .png)
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SaveShare Save Share Save Molecular signatures of self-renewal, differentiation, and lineage choice in multipotential hemopoietic progenitor cells in vitroBruno, L; Hoffmann, R; McBlane, F; Brown, J; Gupta, R; Joshi, C; Pearson, S; Seidl, T; Heyworth, C; Enver, T Share Save Share Save ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesisSchuh, AH; Tipping, AJ; Clark, AJ; Hamlett, I; Guyot, B; Iborra, FJ; Rodriguez, P; Strouboulis, J; Enver, T; Vyas, P; Porcher, C Share Save Injury primes mutation-bearing astrocytes for dedifferentiation in later lifeRagdale, Holly Simpson; Clements, Melanie; Tang, Wenhao; Deltcheva, Elitza; Andreassi, Catia; Lai, Alvina G.; Chang, Wai Hoong; Pandrea, Maria; Andrew, Ivan; Game, Laurence; Uddin, Imran; Ellis, Michael; Enver, Tariq; Riccio, Antonella; Marguerat, Samuel; Parrinello, Simona Share Save Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencingCui, Sijia; McGranahan, Nicholas; Gao, Jing; Chen, Peng; Jiang, Wei; Yang, Lingrong; Ma, Li; Liao, Junfang; Xie, Tian; Xie, Congying; Enver, Tariq; Wu, Shixiu Share Save Share Save Share Save An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemiaGeron, Ifat; Savino, Angela Maria; Fishman, Hila; Tal, Noa; Brown, John; Turati, Virginia A.; James, Chela; Sarno, Jolanda; Hameiri-Grossman, Michal; Lee, Yu Nee; Rein, Avigail; Maniriho, Hillary; Birger, Yehudit; Zemlyansky, Anna; Muler, Inna; Davis, Kara L.; Marcu-Malina, Victoria; Mattson, Nicole; Parnas, Oren; Wagener, Rabea; Fischer, Ute; Barata, Joao T.; Jamieson, Catriona H. M.; Muschen, Markus; Chen, Chun-Wei; Borkhardt, Arndt; Kirsch, Ilan Richard; Nagler, Arnon; Enver, Tariq; Izraeli, Shai Share Save Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation (vol 23, pg 1224, 2021)Gerber, Julia P.; Russ, Jenny; Chandrasekar, Vijay; Offermann, Nina; Lee, Hang-Mao; Spear, Sarah; Guzzi, Nicola; Maida, Simona; Pattabiraman, Sundararaghavan; Zhang, Ruoyu; Kayvanjoo, Amir H.; Datta, Preeta; Kasturiarachchi, Jagath; Sposito, Teresa; Izotova, Natalia; Handler, Kristian; Adams, Peter D.; Marafioti, Teresa; Enver, Tariq; Wenzel, Jorg; Beyer, Marc; Mass, Elvira; Bellodi, Cristian; Schultze, Joachim L.; Capasso, Melania; Nimmo, Rachael; Salomoni, Paolo Share Save Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammationGerber, Julia P.; Russ, Jenny; Chandrasekar, Vijay; Offermann, Nina; Lee, Hang-Mao; Spear, Sarah; Guzzi, Nicola; Maida, Simona; Pattabiraman, Sundararaghavan; Zhang, Ruoyu; Kayvanjoo, Amir H.; Datta, Preeta; Kasturiarachchi, Jagath; Sposito, Teresa; Izotova, Natalia; Haendler, Kristian; Adams, Peter D.; Marafioti, Teresa; Enver, Tariq; Wenzel, Jorg; Beyer, Marc; Mass, Elvira; Bellodi, Cristian; Schultze, Joachim L.; Capasso, Melania; Nimmo, Rachael; Salomoni, Paolo Share Save The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transitionAzzoni, Emanuele; Frontera, Vincent; Anselmi, Giorgio; Rode, Christina; James, Chela; Deltcheva, Elitza M.; Demian, Atanasiu S.; Brown, John; Barone, Cristiana; Patelli, Arianna; Harman, Joe R.; Nicholls, Matthew; Conway, Simon J.; Morrissey, Edward; Jacobsen, Sten Eirik W.; Sparrow, Duncan B.; Harris, Adrian L.; Enver, Tariq; de Bruijn, Marella F. T. R. Share Save Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemiaTurati, Virginia A.; Guerra-Assuncao, Jose Afonso; Potter, Nicola E.; Gupta, Rajeev; Ecker, Simone; Daneviciute, Agne; Tarabichi, Maxime; Webster, Amy P.; Ding, Chuling; May, Gillian; James, Chela; Brown, John; Conde, Lucia; Russell, Lisa J.; Ancliff, Phil; Inglott, Sarah; Cazzaniga, Giovanni; Biondi, Andrea; Hall, Georgina W.; Lynch, Mark; Hubank, Mike; Macaulay, Iain; Beck, Stephan; Van Loo, Peter; Jacobsen, Sten E.; Greaves, Mel; Herrero, Javier; Enver, Tariq Share Save MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and FunctionRoberts, Luke B.; Jowett, Geraldine M.; Read, Emily; Zabinski, Tomas; Berkachy, Rita; Selkirk, Murray E.; Jackson, Ian; Niazi, Umar; Anandagoda, Nelomi; Araki, Masatake; Araki, Kimi; Kasturiarachchi, Jagath; James, Chela; Enver, Tariq; Nimmo, Rachael; Reis, Rita; Howard, Jane K.; Neves, Joana F.; Lord, Graham M. Share Save Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes (vol 10, 19390, 2020)Marshall, A.; Kasturiarachchi, J.; Datta, P.; Guo, Y.; Deltcheva, E.; James, C.; Brown, J.; May, G.; Anandagoda, N.; Jackson, I.; Howard, J. K.; Ghazaly, E.; Brooks, S.; Khwaja, A.; Araki, M.; Araki, K.; Linch, D.; Lord, G. M.; Enver, T.; Nimmo, R. Share Save Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genesMarshall, A.; Kasturiarachchi, J.; Datta, P.; Guo, Y.; Deltcheva, E.; James, C.; Brown, J.; May, G.; Anandagoda, N.; Jackson, I; Howard, J. K.; Ghazaly, E.; Brooks, S.; Khwaja, A.; Araki, M.; Araki, K.; Linch, D.; Lord, G. M.; Enver, T.; Nimmo, R. Share Save Generation and trapping of a mesoderm biased state of human pluripotencyStavish, Dylan; Boiers, Charlotta; Price, Christopher; Frith, Thomas J. R.; Halliwell, Jason; Saldana-Guerrero, Ingrid; Wray, Jason; Brown, John; Carr, Jonathon; James, Chela; Barbaric, Ivana; Andrews, Peter W.; Enver, Tariq Share Save TUMUR MUTATIONS DRIVE DYSFUNCTIONAL T CELL DIFFERENTIATION IN LUNG CANCERGhorani, E.; Reading, J.; Henry, J.; de Massy, M. Robert; Rosenthal, R.; Turati, V.; Furness, A.; Ben Aissa, A.; Saini, S. Kumar; Ramskov, S.; Georgiou, A.; De Mucha, M. Vila; Uddin, I.; Ronel, T.; Salgado, R.; Lund, T.; Herrero, J.; Enver, T.; Hadrup, S.; Hackshaw, A.; Peggs, K.; McGranahan, N.; Chain, B.; Swanton, C.; Quezada, S. Share Save 
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