Julia R. Clarke - Publications, H-index & Citations

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Julia R. Clarke

Universidade Federal do Rio de Janeiro

24H-index

59Paper Count

4.4KCitation Count

Published Papers 27

Publication Date

Exploring the Impact of 3-O-Methylquercetin on Wnt/β-Catenin Pathway Activity and Its Potential in Neural Processes

Pharmaceuticals 2025, Vol. 18, Page 1680

IF4.8

2025-11-06

OAAI

Kamila Leichtweis; Danilo Predes; Marielly C. Mangelli; Hugo Mauricio; Barbara S. M. de Jesus; Clara F. Charlier; Raquel C. da Silva; Giselle F. Passos; Luiz F. S. Oliveira; Clara O. Nogueira; Samir F. A. Cavalcante; Diego M. Lopes; Rodrigo S. Almeida; Danielle C. Bonfim; Alessandro B. C. Simas; Julia R. Clarke; Pedro S. M. Pinheiro; Jose G. Abreu

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Leishmania amazonensis infection induces IL1β-dependent hyperalgesia, while dampening mechanical allodynia in C57BL/6 mice

Virulence

IF5.4

2025-10-31

OAAI

Gustavo G. Perez; Emanuelle V. de Lima; Leticia S. Antonio; Eduardo Matheus M. Vidal; Raissa R. Christoff; Milla B. Paiva; Antônio José S. Gonçalves; Marcia P. Oliveira; Maria Bellio; Robson Coutinho Silva; Robson da Costa; Rodrigo T. Figueiredo; Julia R. Clarke; Herbert L. de Matos Guedes

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Central Zika virus infection causes hypothalamic inflammation and persistent insulin resistance in adult mice

Cell Death & Disease

IF9.6

2025-10-13

OAAI

Emanuelle V. de Lima; Clara O. Nogueira; Raissa R. Christoff; Emylle Costa-Bartuli; Tathiany Igreja-Silva; Mariana Oliveira Lopes da Silva; Daniel Gavino-Leopoldino; Maria Luiza Móra Santos; Felipe Simões Lemos; Jaderson C. da Costa; Gianina T. Venturin; Iranaia Assunção-Miranda; João M. N. Duarte; Claudia P. Figueiredo; Giselle F. Passos; Julia R. Clarke

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Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-01-01

PREAI

Sousa, Gleyton Leonel Silva; Nadur, Nathalia Fonseca; Ferreira, Larissa de Almeida Peixoto; Honorio, Thiago da Silva; Simon, Alice; Cabral, Lucio Mendes; Santos, Maria Luiza Mora; Andrade, Bruna; de Lima, Emanuelle V.; Clarke, Julia R.; Castro, Rosane Nora; Moura, Ricardo Olimpio de; Kummerle, Arthur Eugen

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ATP-P2X7 signaling mediates brain pathology while contributing to viral control in perinatal Zika virus infection

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2024-05-01

PREAI

Leite-Aguiar, Raissa; Cristina-Rodrigues, Fabiana; Ciarlini-Magalhaes, Roberta; Dantas, Danillo Pereira; Alves, Vinicius Santos; Gavino-Leopoldino, Daniel; Neris, Romulo Leao Silva; Schmitz, Felipe; Silveira, Josiane Silva; Kurtenbach, Eleonora; Wyse, Angela T. S.; Clarke, Julia Rosauro; Figueiredo, Claudia Pinto; Assuncao-Miranda, Iranaia; Pimentel-Coelho, Pedro Moreno; Coutinho-Silva, Robson; Savio, Luiz Eduardo Baggio

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SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice

CELL REPORTS

IF6.9

2023-03-01

OAAI

Fontes-Dantas, Fabricia L.; Fernandes, Gabriel G.; Gutman, Elisa G.; De Lima, Emanuelle V.; Antonio, Leticia S.; Hammerle, Mariana B.; Mota-Araujo, Hannah P.; Colodeti, Lilian C.; Araujo, Suzana M. B.; Froz, Gabrielle M.; da Silva, Talita N.; Duarte, Larissa A.; Salvio, Andreza L.; Pires, Karina L.; Leon, Luciane A. A.; Vasconcelos, Claudia Cristina F.; Romao, Luciana; Savio, Luiz Eduardo B.; Silva, Jerson L.; da Costa, Robson; Clarke, Julia R.; Da Poian, Andrea T.; Alves-Leon, Soniza V.; Passos, Giselle F.; Figueiredo, Claudia P.

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Mice lacking 5-lipoxygenase display motor deficits associated with cortical and hippocampal synapse abnormalities

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2022-02-01

PREAI

Barbosa-Silva, Maria Carolina; Campos, Raquel Maria P.; Del Castilo, Ingrid; Franca, Julia, V; Frost, Paula S.; Penido, Carmen; Clarke, Julia R.; Canetti, Claudio; Ribeiro-Resende, Victor T.

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Skeletal Muscle Is an Early Site of Zika Virus Replication and Injury, Which Impairs Myogenesis

JOURNAL OF VIROLOGY

IF3.8

2021-10-27

OAAI

Gavino-Leopoldino, Daniel; Figueiredo, Camila Menezes; Lopes da Silva, Mariana Oliveira; Barcellos, Leticia Goncalves; Silva Neris, Romulo Leao; Miranda Pinto, Laryssa Daniele; Bernardino Araujo, Suzana Maria; Ladislau, Leandro; Benjamim, Claudia Farias; Da Poian, Andrea T.; Clarke, Julia Rosauro; Figueiredo, Claudia Pinto; Assuncao-Miranda, Iranaia

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Innate immune memory mediates increased susceptibility to Alzheimer's disease-like pathology in sepsis surviving mice

BRAIN BEHAVIOR AND IMMUNITY

IF7.6

2021-07-01

OAAI

De Sousa, Virginia L.; Araujo, Suzana B.; Antonio, Leticia M.; Silva-Queiroz, Mariana; Colodeti, Lilian C.; Soares, Carolina; Barros-Aragao, Fernanda; Mota-Araujo, Hannah P.; Alves, Vinicius S.; Coutinho-Silva, Robson; Savio, Luiz Eduardo B.; Ferreira, Sergio T.; Da Costa, Robson; Clarke, Julia R.; Figueiredo, Claudia P.

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Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease

TRANSLATIONAL PSYCHIATRY

IF6.2

2021-04-28

179

OAAI

Silva, Natalia M. Lyra e; Goncalves, Rafaella A.; Pascoal, Tharick A.; Lima-Filho, Ricardo A. S.; Resende, Elisa de Paula Franca; Vieira, Erica L. M.; Teixeira, Antonio L.; de Souza, Leonardo C.; Peny, Julyanna A.; Fortuna, Juliana T. S.; Furigo, Isadora C.; Hashiguchi, Debora; Miya-Coreixas, Vivian S.; Clarke, Julia R.; Abisambra, Jose F.; Longo, Beatriz M.; Donato, Jose, Jr.; Fraser, Paul E.; Rosa-Neto, Pedro; Caramelli, Paulo; Ferreira, Sergio T.; De Felice, Fernanda G.

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Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice (vol 18, pg 1053, 2013)

MOLECULAR PSYCHIATRY

IF10.1

2020-09-02

OAAI

Ledo, J. H.; Azevedo, E. P.; Clarke, J. R.; Ribeiro, F. C.; Figueiredo, C. P.; Foguel, D.; De Felice, F. G.; Ferreira, S. T.

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Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice

SCIENTIFIC REPORTS

IF3.9

2020-04-21

OAAI

Pinheiro, Daniel J. L. L.; Oliveira, Leandro F.; Souza, Isis N. O.; Brogin, Joao A. Ferres; Bueno, Douglas D.; Miranda, Iranaia Assuncao; Da Poian, Andrea T.; Ferreira, Sergio T.; Figueiredo, Claudia P.; Clarke, Julia R.; Cavalheiro, Esper A.; Faber, Jean

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Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

CELL REPORTS

IF6.9

2020-02-01

OAAI

Melo, Helen M.; Seixas da Silva, Gisele da S.; Sant'Ana, Marcella Ramos; Ligo Teixeira, Camila Vieira; Clarke, Julia R.; Miya Coreixas, Vivian S.; de Melo, Bruno C.; Fortuna, Juliana T. S.; Forny-Germano, Leticia; Ledo, Jose Henrique; Oliveira, Maira S.; Figueiredo, Claudia P.; Pardossi-Piquard, Raphaelle; Checler, Frederic; Maria Delgado-Garcia, Jose; Gruart, Agnes; Velloso, Licio A.; Balthazar, Marcio L. F.; Cintra, Dennys E.; Ferreira, Sergio T.; De Felice, Fernanda G.

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Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice

NATURE COMMUNICATIONS

IF15.7

2019-09-05

143

OAAI

Figueiredo, Claudia P.; Barros-Aragao, Fernanda G. Q.; Neris, Romulo L. S.; Frost, Paula S.; Soares, Carolina; Souza, Isis N. O.; Zeidler, Julianna D.; Zamberlan, Daniele C.; de Sousa, Virginia L.; Souza, Amanda S.; Guimaraes, Andre Luis A.; Bellio, Maria; de Souza, Jorge Marcondes; Alves-Leon, Soniza V.; Neves, Gilda A.; Paula-Neto, Heitor A.; Castro, Newton G.; De Felice, Fernanda G.; Assuncao-Miranda, Iranaia; Clarke, Julia R.; Da Poian, Andrea T.; Ferreira, Sergio T.

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Late Neurological Consequences of Zika Virus Infection: Risk Factors and Pharmaceutical Approaches

PHARMACEUTICALS

IF4.8

2019-04-17

OAAI

Souza, Isis N. O.; Barros-Aragao, Fernanda G. Q.; Frost, Paula S.; Figueiredo, Claudia P.; Clarke, Julia R.

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Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice

CELL DEATH & DISEASE

IF9.6

2019-04-11

OAAI

Frost, Paula S.; Barros-Aragao, Fernanda; da Silva, Rachel T.; Venancio, Aline; Matias, Isadora; Lyra e Silva, Natalia M.; Kincheski, Grasielle C.; Pimentel-Coelho, Pedro M.; De Felice, Fernanda G.; Gomes, Flayia C. A.; FerreiraiEi, Sergio T.; Figueiredo, Claudia P.; Clarke, Julia R.

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Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models

NATURE MEDICINE

IF50

2019-01-07

595

OAAI

Lourenco, Mychael V.; Frozza, Rudimar L.; de Freitas, Guilherme B.; Zhang, Hong; Kincheski, Grasielle C.; Ribeiro, Felipe C.; Goncalves, Rafaella A.; Clarke, Julia R.; Beckman, Danielle; Staniszewski, Agnieszka; Berman, Hanna; Guerra, Lorena A.; Forny-Germano, Leticia; Meier, Shelby; Wilcock, Donna M.; de Souza, Jorge M.; Alves-Leon, Soniza; Prado, Vania F.; Prado, Marco A. M.; Abisambra, Jose F.; Tovar-Moll, Fernanda; Mattos, Paulo; Arancio, Ottavio; Ferreira, Sergio T.; De Felice, Fernanda G.

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Metabolic Dysfunction in Alzheimer's Disease: From Basic Neurobiology to Clinical Approaches

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2018-06-12

PREAI

Clarke, Julia R.; Ribeiro, Felipe C.; Frozza, Rudimar L.; De Felice, Fernanda G.; Lourenco, Mychael V.

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Acute and chronic neurological consequences of early-life Zika virus infection in mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2018-06-06

OAAI

de Oliveira Souza, Isis Nem; Frost, Paula S.; Franca, Julia V.; Nascimento-Viana, Jessica B.; Neris, Romulo L. S.; Freitas, Leandro; Pinheiro, Daniel J. L. L.; Nogueira, Clara O.; Neves, Gilda; Chimelli, Leila; De Felice, Fernanda G.; Cavalheiro, Esper A.; Ferreira, Sergio T.; Assuncao-Miranda, Iranaia; Figueiredo, Claudia P.; Da Poian, Andrea T.; Clarke, Julia R.

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The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease

JOURNAL OF PATHOLOGY

IF5.2

2018-04-02

191

OAAI

Batista, Andre F.; Forny-Germano, Leticia; Clarke, Julia R.; Lyra e Silva, Natalia M.; Brito-Moreira, Jordano; Boehnke, Susan E.; Winterborn, Andrew; Coe, Brian C.; Lablans, Ann; Vital, Juliana F.; Marques, Suelen A.; Martinez, Ana M. B.; Gralle, Matthias; Holscher, Christian; Klein, William L.; Houzel, Jean-Christophe; Ferreira, Sergio T.; Munoz, Douglas P.; De Felice, Fernanda G.

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Research Directions