Ross C. Hardison - Publications, H-index & Citations

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Ross C. Hardison

The Pennsylvania State University

89H-index

474Paper Count

6.2WCitation Count

Published Papers 133

Publication Date

RETROFIT: Reference-free deconvolution of cell-type mixtures in spatial transcriptomics

Nature Communications

IF15.7

2026-07-24

OAAI

Roopali Singh; Xi He; Xinyue Wang; Adam Keebum Park; Ross Cameron Hardison; Xiang Zhu; Qunhua Li

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Dissecting polycomb complexes for enhanced fetal hemoglobin production

Blood

IF23.1

2026-06-02

PREAI

Paul J. Kaminski; Kristen Min; Elizabeth A. Traxler; Eugene Khandros; Osheiza Abdulmalik; Bailey Godfrey; Cheryl A. Keller; Belinda M. Giardine; Ross C. Hardison; Junwei Shi; Gerd A. Blobel

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Optimized CRISPR-Cas12a genome-wide screen reveals PTPA phosphatase pathway in fetal hemoglobin silencing

Blood

IF23.1

2026-01-14

PREAI

Elizabeth A. Traxler; Quynn Hotan; Yue Shao; Chad A. Komar; Qingzhou Chen; Megan Saari; A. Josephine Thrasher; Shuchen Yang; Kunhua Qin; Michelle Wang; Scott A. Peslak; Osheiza Abdulmalik; Belinda M. Giardine; Cheryl A. Keller; Ross C. Hardison; Andy J. Minn; Eugene Khandros; Junwei Shi; Gerd A. Blobel

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Highly discriminative globin gene activation by the non-canonical BAF chromatin remodeling complex

Blood

IF23.1

2025-11-19

OAAI

Abhirup Bagchi; Sindhu Billakanti; Vanessa Shehu; Kathryn M. Farrell; Sarah A. Cotteta; Bailey N. Godfrey; Micaela Alpert; Jacob Flores-Zeranski; Krista A. Budinich; Zhuangzhuang Geng; Osheiza Abdulmalik; Belinda M. Giardine; Cheryl A. Keller; Ross C. Hardison; Junwei Shi; Eugene Khandros

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Transcriptome and chromatin accessibility divergence during differentiation of a bipotential progenitor cell population to erythroblasts and megakaryocytes

Journal of Biological Chemistry

IF3.9

2025-10-14

OAAI

Tejaswini Mishra; Belinda M. Giardine; Christapher S. Morrissey; Cheryl A. Keller; Elisabeth F. Heuston; Stacie M. Anderson; Vikram R. Paralkar; Maxim Pimkin; Mitchell J. Weiss; David M. Bodine; Ross C. Hardison

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Single-stranded DNA-binding proteins are essential components of the architectural LDB1 protein complex

Molecular Cell

IF16.6

2025-08-12

OAAI

Xiaokang Wang; Nicholas G. Aboreden; Ying Cai; Jessica C. Lam; Kate A. Henderson; Jiaqi Xiang; Belinda M. Giardine; Ross C. Hardison; Cheryl A. Keller; Lalitha Nagarajan; Stephen J. Brandt; Gerd A. Blobel

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LDB1 establishes multi-enhancer networks to regulate gene expression

MOLECULAR CELL

IF16.6

2025-01-01

OAAI

Aboreden, Nicholas G.; Lam, Jessica C.; Goel, Viraat Y.; Wang, Siqing; Wang, Xiaokang; Midla, Susannah C.; Quijano, Alma; Keller, Cheryl A.; Giardine, Belinda M.; Hardison, Ross C.; Zhang, Haoyue; Hansen, Anders S.; Blobel, Gerd A.

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Defining Oncogenic Transcriptional Networks Regulated By LDB1 in T-Cell Acute Lymphoblastic Leukemia

BLOOD

IF23.1

2024-11-05

PREAI

Bhansali, Rahul S.; Aboreden, Nicholas; Wang, Siqing; Keller, Cheryl A.; Giardine, Belinda M.; Hardison, Ross C.; Blobel, Gerd A.

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LDB1 Establishes Multi-Enhancer Networks to Regulate Erythroid Gene Expression

BLOOD

IF23.1

2024-11-05

PREAI

Aboreden, Nicholas; Lam, Jessica; Goel, Viraat; Wang, Siqing; Wang, Xiaokang; Midla, Susannah; Quijano, Alma; Keller, Cheryl A.; Giardine, Belinda M.; Hardison, Ross C.; Zhang, Haoyue; Hansen, Anders; Blobel, Gerd A.

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YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle

NATURE GENETICS

IF31.8

2024-08-29

PREAI

Lam, Jessica C.; Aboreden, Nicholas G.; Midla, Susannah C.; Wang, Siqing; Huang, Anran; Keller, Cheryl A.; Giardine, Belinda; Henderson, Kate A.; Hardison, Ross C.; Zhang, Haoyue; Blobel, Gerd A.

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Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

GENOME RESEARCH

IF5.5

2024-07-01

OAAI

Xiang, Guanjue; He, Xi; Giardine, Belinda M.; Isaac, Kathryn J.; Taylor, Dylan J.; Mccoy, Rajiv C.; Jansen, Camden; Keller, Cheryl A.; Wixom, Alexander Q.; Cockburn, April; Miller, Amber; Qi, Qian; He, Yanghua; Li, Yichao; Lichtenberg, Jens; Heuston, Elisabeth F.; Anderson, Stacie M.; Luan, Jing; Vermunt, Marit W.; Yue, Feng; Sauria, Michael E. G.; Schatz, Michael C.; Taylor, James; Goettgens, Berthold; Hughes, Jim R.; Higgs, Douglas R.; Weiss, Mitchell J.; Cheng, Yong; Blobel, Gerd A.; Bodine, David M.; Zhang, Yu; Li, Qunhua; Mahony, Shaun; Hardison, Ross C.

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Genome folding principles uncovered in condensin-depleted mitotic chromosomes

NATURE GENETICS

IF31.8

2024-05-27

PREAI

Zhao, Han; Lin, Yinzhi; Lin, En; Liu, Fuhai; Shu, Lirong; Jing, Dannan; Wang, Baiyue; Wang, Manzhu; Shan, Fengnian; Zhang, Lin; Lam, Jessica C.; Midla, Susannah C.; Giardine, Belinda M.; Keller, Cheryl A.; Hardison, Ross C.; Blobel, Gerd A.; Zhang, Haoyue

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HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription (vol 54, 1417, 2022)

NATURE GENETICS

IF31.8

2023-07-31

OAAI

Huang, Peng; Peslak, Scott A.; Ren, Ren; Khandros, Eugene; Qin, Kunhua; Keller, Cheryl A.; Giardine, Belinda; Bell, Henry W.; Lan, Xianjiang; Sharma, Malini; Horton, John R.; Abdulmalik, Osheiza; Chou, Stella T. T.; Shi, Junwei; Crossley, Merlin; Hardison, Ross C.; Cheng, Xiaodong; Blobel, Gerd A.

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CpG islands from the alpha-globin gene cluster increase gene expression in an integration-dependent manner

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

OAAI

Shewchuk, BM; Hardison, RC

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Sequences flanking hypersensitive sites of the β-globin locus control region are required for synergistic enhancement

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Molete, JM; Petrykowska, H; Bouhassira, EE; Feng, YQ; Miller, W; Hardison, RC

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A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse β-globin locus

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

159

OAAI

Bulger, M; Schübeler, D; Bender, MA; Hamilton, J; Farrell, CM; Hardison, RC; Groudine, M

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A T-to-G transversion at nucleotide-567 upstream of HBG2 in a GATA-1 binding motif is associated with elevated hemoglobin F

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Chen, Zhiyi; Luo, Hong-Yuan; Basran, Raveen K.; Hsu, Tien-Huei; Mang, Daniel W. H.; Nuntakam, Lalana; Rosenfield, Cathy G.; Patrinos, George P.; Hardison, Ross C.; Steinberg, Martin H.; Chui, David H. K.

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Genome-Wide Organization of GATA1 and TAL1 Determined at High Resolution

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-18

OAAI

Han, G. Celine; Vinayachandran, Vinesh; Bataille, Alain R.; Park, Bongsoo; Chan-Salis, Ka Yim; Keller, Cheryl A.; Long, Maria; Mahony, Shaun; Hardison, Ross C.; Pugh, B. Franklin

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Gene silencing dynamics are modulated by transiently active regulatory elements

MOLECULAR CELL

IF16.6

2023-03-01

OAAI

Vermunt, Marit W.; Luan, Jing; Zhang, Zhe; Thrasher, A. Josephine; Huang, Anran; Saari, Megan S.; Khandros, Eugene; Beagrie, Robert A.; Zhang, Shiping; Vemulamada, Pranay; Brilleman, Matilda; Lee, Kiwon; Yano, Jennifer A.; Giardine, Belinda M.; Keller, Cheryl A.; Hardison, Ross C.; Blobel, Gerd A.

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Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression

BLOOD ADVANCES

IF7.1

2022-11-28

OAAI

Wakabayashi, Aoi; Kihiu, Maryanne; Sharma, Malini; Thrasher, A. Josephine; Saari, Megan S.; Quesnel-Vallieres, Mathieu; Abdulmalik, Osheiza; Peslak, Scott A.; Khandros, Eugene; Keller, Cheryl A.; Giardine, Belinda M.; Barash, Yoseph; Hardison, Ross C.; Shi, Junwei; Blobel, Gerd A.

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Research Directions