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Christian M. Metallo

university of california san diego

65H-index
308Paper Count
2.1WCitation Count
Published Papers 121
Publication Date
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A genome-scale CRISPRi perturbation atlas of human induced pluripotent stem cells
errNature Biotechnology
IF41.7
err2026-07-01
err0
PREAI
errSami Nourreddine; Yesh Doctor; Amir Dailamy; Yi-Hung Lee; Jan N. Hansen; Rebecca Chinn; Antoine Forget; Benjamin Polacco; Monita Muralidharan; Alina Sigaeva; Sushant Sunder; Emily Pan; Jiahao Gao; Jake Y. Chen; Timothy Clark; Jillian Parker; Kirsten Obernier; Christian Metallo; Trey Ideker; Emma Lundberg; Nevan Krogan; Prashant Mali
errShare
errSave
Modeling lipid homeostasis using stable isotope tracing and flux analysis
errCell Metabolism
IF30.9
err2026-02-20
err0
errOAAI
errKarl Wessendorf-Rodriguez; Maureen L. Ruchhoeft; Christopher W. Murray; Yale Huang; Ethan L. Ashley; Hector M. Galvez; Grace H. McGregor; Shrikaar Kambhampati; Reuben J. Shaw; Christian M. Metallo
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errSave
Resuscitation from Hemorrhagic Shock with a Novel Protein Cocktail Restores Microvascular Perfusion and Protects Vital Organs
errShock
IF2.9
err2026-02-01
err0
PREAI
errMunoz, Carlos J.; Lucas, Daniela; Pires, Ivan S.; Cordes, Thekla; Muller, Cynthia; Govender, Krianthan; Breton, Amanda; Metallo, Christian M.; Palmer, Andre F.; Cabrales, Pedro
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errSave
Dietary methionine mitigates immune-mediated damage by enhancing renal clearance of cytokines
errCell Metabolism
IF30.9
err2026-01-22
err0
errOAAI
errKatia Troha; Shrikaar Kambhampati; Arianna Insenga; Christian M. Metallo; Janelle S. Ayres
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errSave
1-deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway
errCell Chemical Biology
IF7.2
err2026-01-15
err0
errOAAI
errYi-Ting Tsai; Nicolas-Frédéric Lipp; Olivia Seidel; Riya Varma; Aurelie Laguerre; Kristina Solorio-Kirpichyan; Adrian M. Wong; Roberto J. Brea; Grace H. McGregor; Thekla Cordes; Neal K. Devaraj; Lars Kuerschner; Sonya Neal; Christian M. Metallo; Itay Budin
errShare
errSave
p53 increases phospholipid headgroup scavenging in senescence
errNature Cell Biology
IF19.1
err2026-01-07
err0
errOAAI
errJossie J. Yashinskie; Xianbing Zhu; Grace H. McGregor; Karl A. Wessendorf-Rodriguez; Katrina Paras; Julia S. Brunner; Benjamin T. Jackson; Abigail Xie; Richard Koche; Christian M. Metallo; Lydia W. S. Finley
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errSave
Branched-chain fatty acids fire up the peroxisome
errCell Research
IF25.9
err2025-11-13
err0
PREAI
errMartina Wallace; Ramya S. Kuna; Christian M. Metallo
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errSave
Dietary serine supplementation exacerbates type 1 diabetes incidence and severity in non-obese diabetic (NOD) mice
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errJoulia, Emeline; Arechiga, Citlalic; Kerk, Samuel A.; Metallo, Christian M.
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errSave
Enhancing cardiac serine biosynthesis mitigates the progression of dilated cardiomyopathy
errMetabolism
IF0
err2025-09-18
err0
PREAI
errMaryam Kay; Anne-Maj Samuelsson; Nike Bharucha; Xueyi Li; Rohin Ramchandani; Rachel E. Baum; Diego Ruiz; Aurélie Laguerre; Sherin Lajevardi; Shrikaar Kambhampati; Christian M. Metallo; Michael S. Kapiloff; Ioannis Karakikes
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errSave
Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality
errSCIENCE ADVANCES
IF12.5
err2025-02-14
err1
errOAAI
errGallant, Robert M.; Sanchez, Karina K.; Joulia, Emeline; Snyder, Jessica M.; Metallo, Christian M.; Ayres, Janelle S.
errShare
errSave
Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection
errNATURE COMMUNICATIONS
IF15.7
err2025-02-07
err3
errOAAI
errGreene, Trever T.; Jo, Yeara; Chiale, Carolina; Macal, Monica; Fang, Ziyan; Khatri, Fawziyah S.; Codrington, Alicia L.; Kazane, Katelynn R.; Akbulut, Elizabeth; Swaminathan, Shobha; Fujita, Yu; Fitzgerald-Bocarsly, Patricia; Cordes, Thekla; Metallo, Christian; Scott, David A.; Zuniga, Elina I.
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errSave
Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
errCELL METABOLISM
IF30.9
err2025-01-01
err4
PREAI
errGengatharan, Jivani M.; Handzlik, Michal K.; Chih, Zoya Y.; Ruchhoeft, Maureen L.; Secrest, Patrick; Ashley, Ethan L.; Green, Courtney R.; Wallace, Martina; Gordts, Philip L. S. M.; Metallo, Christian M.
errShare
errSave
Quantifying acyl-chain diversity in isobaric compound lipids containing monomethyl branched-chain fatty acids
errJOURNAL OF LIPID RESEARCH
IF4.1
err2024-12-01
err0
errOAAI
errGreen, Courtney R.; Kolar, Matthew J.; Mcgregor, Grace H.; Nelson, Andrew T.; Wallace, Martina; Metallo, Christian M.
errShare
errSave
Impaired branched-chain amino acid (BCAA) catabolism during adipocyte differentiation decreases glycolytic flux
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-12-01
err0
errOAAI
errGreen, Courtney R.; Alaeddine, Lynn M.; Wessendorf-Rodriguez, Karl A.; Turner, Rory; Elmastas, Merve; Hover, Justin D.; Murphy, Anne N.; Ryden, Mikael; Mejhert, Niklas; Metallo, Christian M.; Wallace, Martina
errShare
errSave
Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress
errNATURE METABOLISM
IF20.8
err2024-10-14
err0
PREAI
errKorobkina, Ekaterina D.; Calejman, Camila Martinez; Haley, John A.; Kelly, Miranda E.; Li, Huawei; Gaughan, Maria; Chen, Qingbo; Pepper, Hannah L.; Ahmad, Hafsah; Boucher, Alexander; Fluharty, Shelagh M.; Lin, Te-Yueh; Lotun, Anoushka; Peura, Jessica; Trefely, Sophie; Green, Courtney R.; Vo, Paula; Semenkovich, Clay F.; Pitarresi, Jason R.; Spinelli, Jessica B.; Aydemir, Ozkan; Metallo, Christian M.; Lynes, Matthew D.; Jang, Cholsoon; Snyder, Nathaniel W.; Wellen, Kathryn E.; Guertin, David A.
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errSave
Serine and glycine physiology reversibly modulate retinal and peripheral nerve function
errCELL METABOLISM
IF30.9
err2024-10-01
err0
errOAAI
errLim, Esther W.; Fallon, Regis J.; Bates, Caleb; Ideguchi, Yoichiro; Nagasaki, Takayuki; Handzlik, Michal K.; Joulia, Emeline; Bonelli, Roberto; Green, Courtney R.; Ansell, Brendan R. E.; Kitano, Maki; Polis, Ilham; Roberts, Amanda J.; Furuya, Shigeki; Allikmets, Rando; Wallace, Martina; Friedlander, Martin; Metallo, Christian M.; Gantner, Marin L.
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errSave
Phosphoglycerate Dehydrogenase Gene Therapy for Dilated Cardiomyopathy
errCIRCULATION RESEARCH
IF16.2
err2024-08-02
err0
PREAI
errKay, Maryam; Apel, Anne-Maj; Bharucha, Nike; Baum, Rachel; Li, Xueyi; Laguerre, Aurelie; Metallo, Christian; Kapiloff, Michael; Karakikes, Ioannis
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errSave
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria
errSCIENCE ADVANCES
IF12.5
err2024-04-05
err1
errOAAI
errZhou, Zhenqi; Ma, Alice; Moore, Timothy M.; Wolf, Dane M.; Yang, Nicole; Tran, Peter; Segawa, Mayuko; Strumwasser, Alexander R.; Ren, Wenjuan; Fu, Kai; Wanagat, Jonathan; van der Bliek, Alexander M.; Crosbie-Watson, Rachelle; Liesa, Marc; Stiles, Linsey; Acin-Perez, Rebecca; Mahata, Sushil; Shirihai, Orian; Goodarzi, Mark O.; Handzlik, Michal; Metallo, Christian M.; Walker, David W.; Hevener, Andrea L.
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errSave
Tracing the Diverse Paths of One-Carbon Metabolism in Cancer and Beyond
errCOLD SPRING HARBOR PERSPECTIVES IN MEDICINE
IF10.1
err2024-03-19
err0
PREAI
errLim, Esther W.; Metallo, Christian M.
errShare
errSave
EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth
errCANCER DISCOVERY
IF33.3
err2024-01-25
err8
PREAI
errKuhlmann-Hogan, Alexandra; Cordes, Thekla; Xu, Ziyan; Kuna, Ramya S.; Traina, Kacie A.; Robles-Oteiza, Camila; Ayeni, Deborah; Kwong, Elizabeth M.; Levy, Stellar; Globig, Anna-Maria; Nobari, Matthew M.; Cheng, George Z.; Leibel, Sandra L.; Homer, Robert J.; Shaw, Reuben J.; Metallo, Christian M.; Politi, Katerina; Kaech, Susan M.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Matthew Meyerson
H-index: 223 · Papers: 1.9K
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Lewis C. Cantley
H-index: 214 · Papers: 1.4K
R
Ronald M. Evans
H-index: 211 · Papers: 925
M
M Snyder
H-index: 210 · Papers: 3.3K
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