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David R. Withers

University of Birmingham

47H-index
216Paper Count
8.1KCitation Count
Published Papers 74
Publication Date
Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis
err2025-11-13
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errOAAI
errNaruhiro Kimura; Man Chun Wong; Ben Higgins; Gareth Hardisty; Pei-Chi Huang; Matamoana Muller; Maxym Besh; Daniel A. Patten; Timothy Kendall; Prakash Ramachandran; Adriano G. Rossi; Graham Anderson; Shishir Shetty; David Withers; Atsunori Tsuchiya; Shuji Terai; Wei-Yu Lu
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Cross-talk between ILC2 and Gata3high Tregs locally constrains adaptive type 2 immunity
err2024-07-19
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errOAAI
errStockis, Julie; Yip, Thomas; Moreno-Vicente, Julia; Burton, Oliver; Samarakoon, Youhani; Schuijs, Martijn J.; Raghunathan, Shwetha; Garcia, Celine; Luo, Weike; Whiteside, Sarah K.; Png, Shaun; Simpson, Charlotte; Monk, Stela; Sawle, Ashley; Yin, Kelvin; Barbieri, Johanna; Papadopoulos, Panagiotis; Wong, Hannah; Rodewald, Hans-Reimer; Vyse, Timothy; McKenzie, Andrew N. J.; Cragg, Mark S.; Hoare, Matthew; Withers, David R.; Fehling, Hans Joerg; Roychoudhuri, Rahul; Liston, Adrian; Halim, Timotheus Y. F.
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A first-in-class multimodal immunotherapy for induction of tertiary lymphoid structures as a novel therapeutic strategy for solid tumors
err2024-04-05
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PREAI
errDiers, Anne R.; Guo, Qiuchen; Christie, John D.; Krisky, David; Gaspal, Fabrina M.; Richardson, Erin; Smith, Charlotte G.; Withers, David R.; Croft, Adam P.; Tak, Paul P.; Barone, Francesca
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Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity
err2024-01-24
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errLee, Colin Y. C.; Kennedy, Bethany C.; Richoz, Nathan; Dean, Isaac; Tuong, Zewen K.; Gaspal, Fabrina; Li, Zhi; Willis, Claire; Hasegawa, Tetsuo; Whiteside, Sarah K.; Posner, David A.; Carlesso, Gianluca; Hammond, Scott A.; Dovedi, Simon J.; Roychoudhuri, Rahul; Withers, David R.; Clatworthy, Menna R.
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Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity
err2024-01-24
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errDean, Isaac; Lee, Colin Y. C.; Tuong, Zewen K.; Li, Zhi; Tibbitt, Christopher A.; Willis, Claire; Gaspal, Fabrina; Kennedy, Bethany C.; Matei-Rascu, Veronika; Fiancette, Remi; Nordenvall, Caroline; Lindforss, Ulrik; Baker, Syed Murtuza; Stockmann, Christian; Sexl, Veronika; Hammond, Scott A.; Dovedi, Simon J.; Mjoesberg, Jenny; Hepworth, Matthew R.; Carlesso, Gianluca; Clatworthy, Menna R.; Withers, David R.
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Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3
err2023-11-01
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errTacho-Pinot, Roser; Stamper, Christopher T.; King, James I.; Matei-Rascu, Veronika; Richardson, Erin; Li, Zhi; Roberts, Luke B.; Bassett, John W.; Melo-Gonzalez, Felipe; Fiancette, Remi; Lin, I-Hsuan; Dent, Alexander; Harada, Yohsuke; Finlay, Conor; Mjosberg, Jenny; Withers, David R.; Hepworth, Matthew R.
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LYVE-1+macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
err2023-09-01
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errAnstee, Joanne E.; Feehan, Karen T.; Opzoomer, James W.; Dean, Isaac; Muller, Henrike P.; Bahri, Meriem; Cheung, Tik Shing; Liakath-Ali, Kifayathullah; Liu, Ziyan; Choy, Desmond; Caron, Jonathan; Sosnowska, Dominika; Beatson, Richard; Muliaditan, Tamara; An, Zhengwen; Gillett, Cheryl E.; Lan, Guocheng; Zou, Xiangang; Watt, Fiona M.; Ng, Tony; Burchell, Joy M.; Kordasti, Shahram; Withers, David R.; Lawrence, Toby; Arnold, James N.
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Tspan6 stimulates the chemoattractive potential of breast cancer cells for B cells in an EV- and LXR-dependent manner
err2023-03-01
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errOAAI
errMolostvov, Guerman; Gachechiladze, Mariam; Shaaban, Abeer M.; Hayward, Steven; Dean, Isaac; Dias, Irundika H. K.; Badr, Nahla; Danial, Irini; Mohammed, Fiyaz; Novitskaya, Vera; Paniushkina, Liliia; Speirs, Valerie; Hanby, Andrew; Nazarenko, Irina; Withers, David R.; van Laere, Steven; Long, Heather M.; Berditchevski, Fedor
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In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue
err2022-04-26
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errLi, Zhi; Tuong, Zewen K.; Dean, Isaac; Willis, Claire; Gaspal, Fabrina; Fiancette, Remi; Idris, Suaad; Kennedy, Bethany; Ferdinand, John R.; Penalver, Ana; Cabantous, Mia; Baker, Syed Murtuza; Fry, Jeremy W.; Carlesso, Gianluca; Hammond, Scott A.; Dovedi, Simon J.; Hepworth, Matthew R.; Clatworthy, Menna R.; Withers, David R.
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ILC killer: Qu'est-ce que c'est?
err2022-04-15
err0
PREAI
errWithers, David R.; Hepworth, Matthew R.
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Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression
err2021-11-05
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errOpzoomer, James W.; Anstee, Joanne E.; Dean, Isaac; Hill, Emily J.; Bouybayoune, Ihssane; Caron, Jonathan; Muliaditan, Tamara; Gordon, Peter; Sosnowska, Dominika; Nuamah, Rosamond; Pinder, Sarah E.; Ng, Tony; Dazzi, Francesco; Kordasti, Shahram; Withers, David R.; Lawrence, Toby; Arnold, James N.
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T-bet and RORα control lymph node formation by regulating embryonic innate lymphoid cell differentiation
err2021-09-23
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errStehle, Christina; Rueckert, Timo; Fiancette, Remi; Gajdasik, Dominika W.; Willis, Claire; Ulbricht, Carolin; Durek, Pawel; Mashreghi, Mir-Farzin; Finke, Daniela; Hauser, Anja Erika; Withers, David R.; Chang, Hyun-Dong; Zimmermann, Jakob; Romagnani, Chiara
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Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity
err2021-09-23
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errFiancette, Remi; Finlay, Conor M.; Willis, Claire; Bevington, Sarah L.; Soley, Jake; Ng, Sky T. H.; Baker, Syed Murtuza; Andrews, Simon; Hepworth, Matthew R.; Withers, David R.
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Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo
err2021-05-24
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errBevington, Sarah L.; Fiancette, Remi; Gajdasik, Dominika W.; Keane, Peter; Soley, Jake K.; Willis, Claire M.; Coleman, Daniel J. L.; Withers, David R.; Cockerill, Peter N.
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Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection
err2021-05-01
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errKastele, Verena; Mayer, Johannes; Lee, Edward S.; Papazian, Natalie; Cole, John J.; Cerovic, Vuk; Belz, Gabrielle; Tomura, Michio; Eberl, Gerard; Goodyear, Carl; Maciewicz, Rose A.; Wall, Daniel; Cupedo, Tom; Withers, David R.; Milling, Simon
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Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths
err2021-03-04
err56
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errRoberts, Luke B.; Schnoeller, Corinna; Berkachy, Rita; Darby, Matthew; Pillaye, Jamie; Oudhoff, Menno J.; Parmar, Naveen; Mackowiak, Claire; Sedda, Delphine; Quesniaux, Valerie; Ryffel, Bernhard; Vaux, Rachel; Gounaris, Kleoniki; Berrard, Sylvie; Withers, David R.; Horsnell, William G. C.; Selkirk, Murray E.
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Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice
err2021-01-19
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errPapaioannou, Nikos E.; Salei, Natallia; Rambichler, Stephan; Ravi, Kaushikk; Popovic, Jelena; Kuentzel, Vanessa; Lehmann, Christian H. K.; Fiancette, Remi; Salvermoser, Johanna; Gajdasik, Dominika W.; Mettler, Ramona; Messerer, Denise; Carrelha, Joana; Ohnmacht, Caspar; Haller, Dirk; Stumm, Ralf; Straub, Tobias; Jacobsen, Sten Eirik W.; Schulz, Christian; Withers, David R.; Schotta, Gunnar; Dudziak, Diana; Schraml, Barbara U.
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IL-2/IL-7-inducible factors pioneer the path to T cell differentiation in advance of lineage-defining factors
err2020-09-15
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errBevington, Sarah L.; Keane, Peter; Soley, Jake K.; Tauch, Saskia; Gajdasik, Dominika W.; Fiancette, Remi; Matei-Rascu, Veronika; Willis, Claire M.; Withers, David R.; Cockerill, Peter N.
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