Not logged inA GENOME-WIDE CRISPR/CAS9 SCREEN IN GLIOBLASTOMA STEM CELLS UNVEILS SYNTHETIC LETHAL INTERACTIONS AND RESISTANCE MECHANISMS OF JIN001, A BLOOD-BRAIN BARRIER-PENETRANT HSP90 INHIBITOR
Chen, Xiaohua; Anvar, Nazanin Esmaeili; Colic, Medina; Xu, Jihong; Liang, Jiyong; Sharma, Pratibha; Huo, Longfei; Sugur, Harsha S.; Hart, Traver; Puduvalli, Vinay K. .png)
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SaveIn vivo CRISPR screens identify Mga as an immunotherapy target in triple- negative breast cancerFeng, Xu; Yang, Chang; Huang, Yuanjian; Su, Dan; Wang, Chao; Wilson, Lori Lyn; Yin, Ling; Tang, Mengfan; Li, Siting; Chen, Zhen; Zhu, Dandan; Wang, Shimin; Zhang, Shengzhe; Zhang, Jie; Zhang, Huimin; Nie, Litong; Huang, Min; Park, Jae - Il; Hart, Traver; Jiang, Dadi; Jiang, Kuirong; Chen, Junjie Share Save Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platformAnvar, Nazanin Esmaeili; Lin, Chenchu; Ma, Xingdi; Wilson, Lori L.; Steger, Ryan; Sangree, Annabel K.; Colic, Medina; Wang, Sidney H.; Doench, John G.; Hart, Traver Share Save CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbonZhu, Yan; Zhang, Dengyong; Shukla, Pooja; Jung, Young-Ho; Malgulwar, Prit Benny; Chagani, Sharmeen; Colic, Medina; Benjamin, Sarah; Copland III, John A.; Tan, Lin; Lorenzi, Philip L.; Javle, Milind; Huse, Jason T.; Roszik, Jason; Hart, Traver; Kwong, Lawrence N. Share Save Mutant GNAS drives glycolytic dependency in intraductal papillary mucinous neoplasms of the pancreasMakino, Yuki; Rajapakshe, Kimal; Yee, Nathaniel; Siemann, Megan; Min, Jimin; Selvanesan, Benson Chellakkan; Thege, Fredrik; Sagara, Akiko; Dutta, Prasanta; Bhattacharya, Pratip; Dede, Merve; Hart, Traver; Maitra, Anirban Share Save FACS-based genome-wide CRISPR screens define key regulators of DNA damage signaling pathwaysHuang, Min; Yao, Fuwen; Nie, Litong; Wang, Chao; Su, Dan; Zhang, Huimin; Li, Siting; Tang, Mengfan; Feng, Xu; Yu, Bin; Chen, Zhen; Wang, Shimin; Yin, Ling; Mou, Lisha; Hart, Traver; Chen, Junjie Share Save Share Save Share Save Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosisLiu, Xiaoguang; Nie, Litong; Zhang, Yilei; Yan, Yuelong; Wang, Chao; Colic, Medina; Olszewski, Kellen; Horbath, Amber; Chen, Xiong; Lei, Guang; Mao, Chao; Wu, Shiqi; Zhuang, Li; Poyurovsky, Masha V.; James You, M.; Hart, Traver; Billadeau, Daniel D.; Chen, Junjie; Gan, Boyi Share Save Share Save Share Save Share Save Integrated screens uncover a cell surface tumor suppressor gene KIRREL involved in Hippo pathwayWang, Chao; Feng, Xu; Su, Dan; Chen, Zhen; Wang, Shimin; Tang, Mengfan; Huang, Min; Nie, Litong; Zhang, Huimin; Li, Siting; Yin, Ling; Johnson, Randy L.; Hart, Traver; Chen, Junjie Share Save Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressorsFeng, Xu; Tang, Mengfan; Dede, Merve; Su, Dan; Pei, Guangsheng; Jiang, Dadi; Wang, Chao; Chen, Zhen; Li, Mi; Nie, Litong; Xiong, Yun; Li, Siting; Park, Jeong-Min; Zhang, Huimin; Huang, Min; Szymonowicz, Klaudia; Zhao, Zhongming; Hart, Traver; Chen, Junjie Share Save Share Save Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cellsLenoir, W. Frank; Morgado, Micaela; DeWeirdt, Peter C.; McLaughlin, Megan; Griffith, Audrey L.; Sangree, Annabel K.; Feeley, Marissa N.; Anvar, Nazanin Esmaeili; Kim, Eiru; Bertolet, Lori L.; Colic, Medina; Dede, Merve; Doench, John G.; Hart, Traver Share Save Share Save AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylaseYoshihama, Yohei; LaBella, Kyle A.; Kim, Eiru; Bertolet, Lori; Colic, Medina; Li, Jiexi; Shang, Xiaoying; Wu, Chang-Jiun; Spring, Denise J.; Wang, Y. Alan; Hart, Traver; DePinho, Ronald A. Share Save Genetic vulnerabilities upon inhibition of DNA damage responseWang, Chao; Tang, Mengfan; Chen, Zhen; Nie, Litong; Li, Siting; Xiong, Yun; Szymonowicz, Klaudia Anna; Park, Jeong-Min; Zhang, Huimin; Feng, Xu; Huang, Min; Su, Dan; Hart, Traver; Chen, Junjie Share Save DNA polymerase. compensates for Fanconi anemia pathway deficiency by countering DNA replication stressWang, Rui; Lenoir, Walter F.; Wang, Chao; Su, Dan; McLaughlin, Megan; Hu, Qianghua; Shen, Xi; Tian, Yanyan; Klages-Mundt, Naeh; Lynn, Erica; Wood, Richard D.; Chen, Junjie; Hart, Traver; Li, Lei Share Save 
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