Robert P. Mecham - Publications, H-index & Citations

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Robert P. Mecham

washington university (wustl)

84H-index

406Paper Count

2.5WCitation Count

Published Papers 140

Publication Date

Loss of MFAP5 and Its Effect on Skin Homeostasis and Wound Healing

FASEB JOURNAL

IF4.2

2025-12-05

OAAI

Han, Chen; Yuan, Heidi; Koh, Timothy J.; Chen, Lin; Mecham, Robert P.; Dipietro, Luisa A.

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Elastin Regulation of Vasoreactivity in Resistance Arteries

HYPERTENSION

IF8.2

2025-12-01

PREAI

Ruddiman, Claire A.; O'donnell, Brooke L.; Wolpe, Abigail; Blagrove, Nyla; Dunaway, Luke S.; Lin, Chien-Jung; Best, Angela K.; Cortese-Krott, Miriam M.; Mecham, Robert P.; Wagenseil, Jessica E.; Isakson, Brant E.

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Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1

JCI INSIGHT

IF6.1

2023-05-08

OAAI

Ruddiman, Claire A.; Peckham, Richard; Luse, Melissa A.; Chen, Yen-Lin; Kuppusamy, Maniselvan; Corliss, Bruce A.; Hall, P. Jordan; Lin, Chien-Jung; Peirce, Shayn M.; Sonkusare, Swapnil K.; Mecham, Robert P.; Wagenseil, Jessica E.; Isakson, Brant E.

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Targeting Epidermal Growth Factor Receptor to Stimulate Elastic Matrix Regenerative Repair

TISSUE ENGINEERING PART A

IF2.9

2023-04-01

OAAI

Dayal, Simran; Broekelmann, Thomas; Mecham, Robert P.; Ramamurthi, Anand

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Developmental expression of latent transforming growth factor β binding protein 2 and its requirement early in mouse development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

109

OAAI

Shipley, JM; Mecham, RP; Maus, E; Bonadio, J; Rosenbloom, J; McCarthy, RT; Baumann, ML; Frankfater, C; Segade, F; Shapiro, SD

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Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

205

OAAI

McLaughlin, PJ; Chen, QY; Horiguchi, M; Starcher, BC; Stanton, JB; Broekelmann, TJ; Marmorstein, AD; McKay, B; Mecham, R; Nakamura, T; Marmorstein, LY

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Fibulin-2 is dispensable for mouse development and elastic fiber formation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Sicot, Francois-Xavier; Tsuda, Takeshi; Markova, Dessislava; Klement, John F.; Arita, Machiko; Zhang, Rui-Zhu; Pan, Te-Cheng; Mecham, Robert P.; Birk, David E.; Chu, Mon-Li

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SVEP1 is an endogenous ligand for the orphan receptor PEAR1 (vol 14, 850, 2023)

NATURE COMMUNICATIONS

IF15.7

2023-03-17

OAAI

Elenbaas, Jared S.; Pudupakkam, Upasana; Ashworth, Katrina J.; Kang, Chul Joo; Patel, Ved; Santana, Katherine; Jung, In-Hyuk; Lee, Paul C.; Burks, Kendall H.; Amrute, Junedh M.; Mecham, Robert P.; Halabi, Carmen M.; Alisio, Arturo; Di Paola, Jorge; Stitziel, Nathan O.

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SVEP1 is an endogenous ligand for the orphan receptor PEAR1

NATURE COMMUNICATIONS

IF15.7

2023-02-15

OAAI

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Progerin induces a phenotypic switch in vascular smooth muscle cells and triggers replication stress and an aging-associated secretory signature

GEROSCIENCE

IF5.4

2022-12-09

OAAI

Coll-Bonfill, Nuria; Mahajan, Urvashi; Shashkova, Elena V. V.; Lin, Chien-Jung; Mecham, Robert P. P.; Gonzalo, Susana

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The internal elastic lamina of resistance arteries facilitates vasodilation

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Ruddiman, Claire A.; Milosek, Victoria; Peckham, Richard; Mecham, Robert P.; Wagenseil, Jessica E.; Isakson, Brant E.

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Endothelial dysfunction drives aneurysm development in Marfan syndrome

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Cantalupo, Anna; Asano, Keiichi; Hansen, Jens; Halabi, Carmen; Mecham, Robert; Iyengar, Ravi; Ramirez, Francesco

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JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-03-01

OAAI

Dave, Jui M.; Chakraborty, Raja; Ntokou, Aglaia; Saito, Junichi; Saddouk, Fatima Z.; Feng, Zhonghui; Misra, Ashish; Tellides, George; Riemer, Robert K.; Urban, Zsolt; Kinnear, Caroline; Ellis, James; Mital, Seema; Mecham, Robert; Martin, Kathleen A.; Greif, Daniel M.

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JNK2 Gene Silencing for Elastic Matrix Regenerative Repair

TISSUE ENGINEERING PART A

IF2.9

2022-03-01

OAAI

Carney, Sarah; Broekelmann, Tom; Mecham, Robert; Ramamurthi, Anand

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Passive biaxial mechanical behavior of newborn mouse aorta with and without elastin

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS

IF3.5

2022-02-01

OAAI

Kim, Jungsil; Cocciolone, Austin J.; Staiculescu, Marius C.; Mecham, Robert P.; Wagenseil, Jessica E.

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Vascular Smooth Muscle Cell Subpopulations and Neointimal Formation in Mouse Models of Elastin Insufficiency

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2021-12-01

OAAI

Lin, Chien-Jung; Hunkins, Bridget M.; Roth, Robyn A.; Lin, Chieh-Yu; Wagenseil, Jessica E.; Mecham, Robert P.

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Tissue-specific smooth muscle cell subtypes identified by transcriptional profiling

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2021-10-01

PREAI

Lin, Chien-Jung; Mecham, Robert P.

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SVEP1 is a human coronary artery disease locus that promotes atherosclerosis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-03-24

OAAI

Jung, In-Hyuk; Elenbaas, Jared S.; Alisio, Arturo; Santana, Katherine; Young, Erica P.; Kang, Chul Joo; Kachroo, Puja; Lavine, Kory J.; Razani, Babak; Mecham, Robert P.; Stitziel, Nathan O.

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Inhibition of NOX1 Mitigates Blood Pressure Increases in Elastin Insufficiency

FUNCTION

IF3.8

2021-03-15

OAAI

Troia, Angela; Knutsen, Russell H.; Halabi, Carmen M.; Malide, Daniela; Yu, Zu Xi; Wardlaw-Pickett, Amanda; Kronquist, Elise K.; Tsang, Kit Man; Kovacs, Attila; Mecham, Robert P.; Kozel, Beth A.

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Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified miceS

JCI INSIGHT

IF6.1

2021-03-08

OAAI

Zhang, Haixia; Hanson, Alex; de Almeida, Tobias Scherf; Emfinger, Christopher; McClenaghan, Conor; Harter, Theresa; Yan, Zihan; Cooper, Paige E.; Brown, G. Schuyler; Arakel, Eric C.; Mecham, Robert P.; Kovacs, Atilla; Halabi, Carmen M.; Schwappach, Blanche; Remedi, Maria S.; Nichols, Colin G.

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Research Directions