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H

H. Lee Sweeney

University of Florida

92H-index
405Paper Count
4.6WCitation Count
Published Papers 161
Publication Date
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Development of clinically viable non-muscle myosin II small molecule inhibitors
errCell
IF42.5
err2025-07-01
err0
PREAI
errLaszlo Radnai; Erica J. Young; Carlos Kikuti; Katalin Toth; Minghai Zhou; Madalyn Hafenbreidel; Rebecca F. Stremel; Li Lin; Paolo Pasetto; Xiaomin Jin; Aagam Patel; Michael Conlon; Sherri B. Briggs; Leïla Heidsieck; H. Lee Sweeney; James Sellers; Teresa Krieger-Burke; William H. Martin; Jay Sisco; Steven Young; Paul Pearson; Gavin Rumbaugh; Gian Luca Araldi; Steven K. Duddy; Michael D. Cameron; Matthew Surman; Anne Houdusse; Patrick R. Griffin; Theodore M. Kamenecka; Courtney A. Miller
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errSave
Spatiotemporal transcriptomic mapping of regenerative inflammation in skeletal muscle reveals dynamic multilayered tissue architecture
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-08-27
err0
errOAAI
errPatsalos, Andreas; Halasz, Laszlo; Oleksak, Darby; Wei, Xiaoyan; Nagy, Gergely; Tzerpos, Petros; Conrad, Thomas; Hammers, David W.; Sweeney, H. Lee; Nagy, Laszlo
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Cardiomyopathy in Duchenne Muscular Dystrophy and the Potential for Mitochondrial Therapeutics to Improve Treatment Response
errCELLS
IF5.2
err2024-07-09
err2
errOAAI
errGandhi, Shivam; Sweeney, H. Lee; Hart, Cora C.; Han, Renzhi; Perry, Christopher G. R.
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errSave
Potential limitations of microdystrophin gene therapy for Duchenne muscular dystrophy
errJCI INSIGHT
IF6.1
err2024-05-07
err6
errOAAI
errHart, Cora C.; Lee, Young Il; Xie, Jun; Gao, Guangping; Lin, Brian L.; Hammers, David W.; Sweeney, H. Lee
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errSave
Myospreader improves gene editing in skeletal muscle by myonuclear propagation
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-30
err1
errOAAI
errPoukalov, Kiril K.; Valero, M. Carmen; Muscato, Derek R.; Adams, Leanne M.; Chun, Heejae; Lee, Young Il; Andrade, Nadja S.; Zeier, Zane; Sweeney, H. Lee; Wang, Eric T.
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Draft Guidance for Industry Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and Related Dystrophinopathies - Developing Potential Treatments for the Entire Spectrum of Disease
errJOURNAL OF NEUROMUSCULAR DISEASES
IF3.4
err2024-02-13
err2
errOAAI
errMcDonald, Craig; Camino, Eric; Escandon, Rafael; Finkel, Richard S.; Fischer, Ryan; Flanigan, Kevin; Furlong, Pat; Juhasz, Rose; Martin, Ann S.; Villa, Chet; Sweeney, H. Lee
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errSave
Myo10 tail is crucial for promoting long filopodia
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-01-01
err1
errOAAI
errChen, Xingxiang; Arciola, Jeffrey M.; il Lee, Young; Wong, Pak Hung Philip; Yin, Haoran; Tao, Quanqing; Jin, Yuqi; Qin, Xianan; Sweeney, H. Lee; Park, Hyokeun
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Clinical importance of changes in magnetic resonance biomarkers for Duchenne muscular dystrophy
errANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
IF3.9
err2023-11-06
err1
errOAAI
errWillcocks, Rebecca J.; Barnard, Alison M.; Daniels, Michael J.; Forbes, Sean C.; Triplett, William T.; Brandsema, John F.; Finanger, Erika L.; Rooney, William D.; Kim, Sarah; Wang, Dah-Jyuu; Lott, Donovan J.; Senesac, Claudia R.; Walter, Glenn A.; Sweeney, H. Lee; Vandenborne, Krista
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errSave
How myosin VI traps its off-state, is activated and dimerizes
errNATURE COMMUNICATIONS
IF15.7
err2023-10-23
err1
errOAAI
errCanon, Louise; Kikuti, Carlos; Planelles-Herrero, Vicente J.; Lin, Tianming; Mayeux, Franck; Sirkia, Helena; Lee, Young il; Heidsieck, Leila; Velikovsky, Leonid; David, Amandine; Liu, Xiaoyan; Moussaoui, Dihia; Forest, Emma; Hook, Peter; Petersen, Karl J.; Morgan, Tomos E.; Di Cicco, Aurelie; Sires-Campos, Julia; Derivery, Emmanuel; Levy, Daniel; Delevoye, Cedric; Sweeney, H. Lee; Houdusse, Anne
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Mechanisms of Skeletal Muscle Atrophy and Molecular Circuitry of Stem Cell Fate in Skeletal Muscle Regeneration and Aging
errJOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
IF3.8
err2023-06-16
err12
errOAAI
errBodine, Sue C.; Sinha, Indranil; Sweeney, Hugh Lee
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errSave
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-05-15
err11
errOAAI
errRussell, Alan J.; DuVall, Mike; Barthel, Ben; Qian, Ying; Peter, Angela K.; Newell-Stamper, Breanne L.; Hunt, Kevin; Lehman, Sarah; Madden, Molly; Schlachter, Stephen; Robertson, Ben; Van Deusen, Ashleigh; Rodriguez, Hector M.; Vera, Carlos; Su, Yu; Claflin, Dennis R.; V. Brooks, Susan; Nghiem, Peter; Rutledge, Alexis; Juehne, Twlya I.; Yu, Jinsheng; Barton, Elisabeth R.; Luo, Yangyi E.; Patsalos, Andreas; Nagy, Laszlo; Sweeney, H. Lee; Leinwand, Leslie A.; Koch, Kevin
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errSave
Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-05-13
err15
errOAAI
errNeyroud, Daria; Laitano, Orlando; Dasgupta, Aneesha; Lopez, Christopher; Schmitt, Rebecca E.; Schneider, Jessica Z.; Hammers, David W.; Sweeney, H. Lee; Walter, Glenn A.; Doles, Jason; Judge, Sarah M.; Judge, Andrew R.
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errSave
Blocking muscle wasting via deletion of the muscle specific E3 ligase, MuRF1, impedes pancreatic tumor growth
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errNeyroud, Daria; Laitano, Orlando; Lopez, Christopher; Hammers, David W.; Sweeney, H. Lee; Walter, Glenn A.; Judge, Sarah M.; Judge, Andrew R.
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errSave
Evaluating Genetic Modifiers of Duchenne Muscular Dystrophy Disease Progression Using Modeling and MRI
errNEUROLOGY
IF8.5
err2022-11-22
err7
errOAAI
errBarnard, Alison M.; Hammers, David W.; Triplett, William T.; Kim, Sarah; Forbes, Sean C.; Willcocks, Rebecca J.; Daniels, Michael J.; Senesac, Claudia R.; Lott, Donovan J.; Arpan, Ishu; Rooney, William D.; Wang, Richard T.; Nelson, Stanley F.; Sweeney, Lee; Vandenborne, Krista; Walter, Glenn A.
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errSave
High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism
errELIFE
IF0
err2021-11-23
err26
PREAI
errPospich, Sabrina; Sweeney, H. Lee; Houdusse, Anne; Raunser, Stefan
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errSave
Filopodia powered by class x myosin promote fusion of mammalian myoblasts
errELIFE
IF0
err2021-09-14
err9
PREAI
errHammers, David W.; Hart, Cora C.; Matheny, Michael K.; Heimsath, Ernest G.; Lee, Young il; Hammer, John A., III; Cheney, Richard E.; Sweeney, H. Lee
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errSave
The D2.mdx mouse as a preclinical model of the skeletal muscle pathology associated with Duchenne muscular dystrophy
errSCIENTIFIC REPORTS
IF3.9
err2020-08-21
err69
errOAAI
errHammers, David W.; Hart, Cora C.; Matheny, Michael K.; Wright, Lillian A.; Armellini, Megan; Barton, Elisabeth R.; Sweeney, H. Lee
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errSave
Upper and Lower Extremities in Duchenne Muscular Dystrophy Evaluated with Quantitative MRI and Proton MR Spectroscopy in a Multicenter Cohort
errRADIOLOGY
IF15.2
err2020-06-01
err30
errOAAI
errForbes, Sean C.; Arora, Harneet; Willcocks, Rebecca J.; Triplett, William T.; Rooney, William D.; Barnard, Alison M.; Alabasi, Umar; Wang, Dah-Jyuu; Lott, Donovan J.; Senesac, Claudia R.; Harrington, Ann T.; Finanger, Erika L.; Tennekoon, Gihan, I; Brandsema, John; Daniels, Michael J.; Sweeney, H. Lee; Walter, Glenn A.; Vandenborne, Krista
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errSave
MR biomarkers predict clinical function in Duchenne muscular dystrophy
errNEUROLOGY
IF8.5
err2020-03-03
err65
errOAAI
errBarnard, Alison M.; Willcocks, Rebecca J.; Triplett, William T.; Forbes, Sean C.; Daniels, Michael J.; Chakraborty, Saptarshi; Lott, Donovan J.; Senesac, Claudia R.; Finanger, Erika L.; Harrington, Ann T.; Tennekoon, Gihan; Arora, Harneet; Wang, Dah-Jyuu; Sweeney, H. Lee; Rooney, William D.; Walter, Glenn A.; Vandenborne, Krista
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errSave
Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle
errJCI INSIGHT
IF6.1
err2020-01-16
err23
errOAAI
errHammers, David W.; Hart, Cora C.; Patsalos, Andreas; Matheny, Michael K.; Wright, Lillian A.; Nagy, Laszlo; Sweeney, H. Lee
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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J
Jeffery D. Molkentin
H-index: 141 · Papers: 642
C
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H-index: 139 · Papers: 1.2K
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