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Christian Grimm

Goethe University Frankfurt

59H-index
293Paper Count
1.1WCitation Count
Published Papers 82
Publication Date
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Phospholipid-driven conformational switching of HCV NS5A links protein folding to replication membrane remodeling
errScience Advances
IF12.5
err2026-04-03
err0
errOAAI
errAnna V. Bulankina; Rebecca M. Richter; James H. Nettles; Daisuke Yamane; Christian Grimm; Yasaman Karami; Richard A. Stanton; Bianca Introini; Jonas Hermann; Hanaa Charif; Mia S. König; Claudia Stroß; Cristina Ortiz; Nico Kraus; Daniel Wood; Facundo Galceran; Rupert Abele; Bernard Maigret; Raymond F. Schinazi; Stefan Zeuzem; Ricardo M. Biondi; MinKyung Yi; Robert Tampé; Mikhail Kudryashev; Christoph Welsch
errShare
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HIF1 activity in photoreceptors drives type 3 neovascularization and retinal atrophy in a new mouse model of age-related macular degeneration
errCell Death & Disease
IF9.6
err2025-10-06
err0
errOAAI
errFredy Geiger; Thomas Heigl; Luca Merolla; Marcus Yong; Gabriele M. Wögenstein; Larissa P. Govers; Ioanna Tsioti; Antonia Fottner; Marijana Samardzija; Christian Grimm
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errSave
A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD
errMolecular Therapy
IF12
err2025-09-27
err0
errOAAI
errLynn J.A. Ebner; Cornelia Imsand; Duygu Karademir; Florian Peters; Eva Kiessling; Antonia Fottner; Claudia Matter; Diego S. Fajardo; Luca Merolla; Gabriele M. Wögenstein; Ioanna Tsioti; Larissa P. Govers; Frank Blaser; Isabelle Meneau; Sanford L. Boye; Shannon E. Boye; Christian Grimm; Marijana Samardzija
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errSave
Photoreceptor activation drives the expression of the immediate-early gene Egr1 in inner retinal neurons
errExperimental Eye Research
IF2.7
err2025-08-26
err0
errOAAI
errLuca Merolla; Marijana Samardzija; Corinne Kostic; Christian Grimm
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errSave
Oxygen-dependent alternative mRNA splicing and a cone-specific motor protein revealed by single-cell RNA sequencing in hypoxic retinas
errEXPERIMENTAL EYE RESEARCH
IF2.7
err2025-02-01
err0
errOAAI
errEbner, Lynn J. A.; Karademir, Duygu; Notzli, Sarah; Wogenstein, Gabriele M.; Samardzija, Marijana; Grimm, Christian
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errSave
Final overall survival (OS) from the phase III ATALANTE/ENGOT-ov29 trial evaluating atezolizumab (Atz) versus placebo with standard chemotherapy (Cx) plus bevacizumab (bev) in ovarian cancer (OC) patients (pts) with platinum-sensitive relapse (PSR)
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err1
PREAI
errKurtz, J. E.; Pujade-Lauraine, E.; Oaknin, A.; Belin, L.; Grimm, C.; Kocian, R.; Denys, H.; Rosengarten, O. S.; Follana, P.; Sehouli, J.; Martinez-Garcia, J.; Alexandre, J.; Hardy-Bessard, A-C.; Frenel, J-S.; Sabatier, R.; Gladieff, L.; Rouge, T. De La Motte; Lamichhane, N. Bonichon; Kalbacher, E.; Heitz, F.
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errSave
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation
errMOLECULAR NEURODEGENERATION
IF17.5
err2023-03-07
err6
errOAAI
errTodorova, Vyara; Stauffacher, Mia Fee; Ravotto, Luca; Notzli, Sarah; Karademir, Duygu; Ebner, Lynn J. A.; Imsand, Cornelia; Merolla, Luca; Hauck, Stefanie. M. M.; Samardzija, Marijana; Saab, Aiman. S. S.; Barros, L. Felipe; Weber, Bruno; Grimm, Christian
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errSave
An endo-lysosomal Ca2+ store in cardiomyocytes controlled by OCaR proteins determines fatal tachyarrhythmias
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2022-12-01
err0
PREAI
errBerlin, Michael; Londono, Juan Eduardo Camacho; Ottenheijm, Roger; Kraft, Axel; Bacmeister, Lucas; Tsvilovskyy, Volodymyr; Meyer, Soeren; Hennis, Konstantin; Gerndt, Susanne; Offen, Kira; Leuschner, Florian; Bracher, Franz; Fenske, Stefanie; Biel, Martin; Hansen, Arne; Grimm, Christian; Wahl-Schott, Christian; Freichel, Marc
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errSave
Retinal Layer Separation (ReLayS) method enables the molecular analysis of photoreceptor segments and cell bodies, as well as the inner retina
errSCIENTIFIC REPORTS
IF3.9
err2022-11-23
err4
errOAAI
errTodorova, Vyara; Merolla, Luca; Karademir, Duygu; Wogenstein, Gabriele M.; Behr, Julian; Ebner, Lynn J. A.; Samardzija, Marijana; Grimm, Christian
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errSave
Increased H3K27 trimethylation contributes to cone survival in a mouse model of cone dystrophy
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2022-07-10
err3
errOAAI
errMiller, Annie L.; Fuller-Carter, Paula, I; Masarini, Klaudija; Samardzija, Marijana; Carter, Kim W.; Rashwan, Rabab; Lim, Xin Ru; Brunet, Alicia A.; Chopra, Abha; Ram, Ramesh; Grimm, Christian; Ueffing, Marius; Carvalho, Livia S.; Trifunovic, Dragana
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errSave
Stanniocalcin2, but Not Stanniocalcin1, Responds to Hypoxia in a HIF1-Dependent Manner in the Retina
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2022-06-23
err5
errOAAI
errAil, Divya; Samardzija, Marijana; Chang, Andy C. M.; Keck, Jadwiga; Reddel, Roger R.; Grimm, Christian
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errSave
Imaging of retina cellular and subcellular structures using ptychographic hard X-ray tomography
errJOURNAL OF CELL SCIENCE
IF3.6
err2021-10-14
err0
errOAAI
errPanneels, Valerie; Diaz, Ana; Imsand, Cornelia; Guizar-Sicairos, Manuel; Mueller, Elisabeth; Bittermann, Anne Greet; Ishikawa, Takashi; Menzel, Andreas; Kaech, Andres; Holler, Mirko; Grimm, Christian; Schertler, Gebhard
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errSave
Circadian regulation of vertebrate cone photoreceptor function
errELIFE
IF0
err2021-09-22
err10
PREAI
errZang, Jingjing; Gesemann, Matthias; Keim, Jennifer; Samardzija, Marijana; Grimm, Christian; Neuhauss, Stephan C. F.
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errSave
Transcriptomic analysis of the mouse retina after acute and chronic normobaric and hypobaric hypoxia
errSCIENTIFIC REPORTS
IF3.9
err2021-08-17
err19
errOAAI
errEbner, L. J. A.; Samardzija, M.; Storti, F.; Todorova, V.; Karademir, D.; Behr, J.; Simpson, F.; Thiersch, M.; Grimm, C.
errShare
errSave
Multivariate data analysis of capacitance frequency scanning for online monitoring of viable cell concentrations in small-scale bioreactors (vol 412, pg 2089, 2020)
errANALYTICAL AND BIOANALYTICAL CHEMISTRY
IF3.8
err2021-07-13
err0
errOAAI
errMetze, Sabrina; Blioch, Stefanie; Matuszczyk, Jens; Greller, Gerhard; Grimm, Christian; Scholz, Jochen; Hoehse, Marek
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errSave
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2020-11-06
err26
errOAAI
errSamardzija, Marijana; Corna, Andrea; Gomez-Sintes, Raquel; Jarboui, Mohamed Ali; Armento, Angela; Roger, Jerome E.; Petridou, Eleni; Haq, Wadood; Paquet-Durand, Francois; Zrenner, Eberhart; de la Villa, Pedro; Zeck, Guenther; Grimm, Christian; Boya, Patricia; Ueffing, Marius; Trifunovic, Dragana
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errSave
Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-10-01
err11
errOAAI
errDultz, Georg; Shimakami, Tetsuro; Schneider, Markus; Murai, Kazuhisa; Yamane, Daisuke; Marion, Antoine; Zeitler, Tobias M.; Stross, Claudia; Grimm, Christian; Richter, Rebecca M.; Baeumer, Katrin; Yi, MinKyung; Biondi, Ricardo M.; Zeuzem, Stefan; Tampe, Robert; Antes, Iris; Lange, Christian M.; Welsch, Christoph
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errSave
PEDF deficiency increases the susceptibility of rd10 mice to retinal degeneration
errEXPERIMENTAL EYE RESEARCH
IF2.7
err2020-09-01
err15
errOAAI
errDixit, Shivani; Polato, Federica; Samardzija, Marijana; Abu-Asab, Mones; Grimm, Christian; Crawford, Susan E.; Becerra, S. Patricia
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errSave
Hif1a and Hif2a can be safely inactivated in cone photoreceptors
errSCIENTIFIC REPORTS
IF3.9
err2019-11-06
err10
errOAAI
errSamardzija, Marijana; Barben, Maya; Todorova, Vyara; Klee, Katrin; Storti, Federica; Grimm, Christian
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errSave
Systemic knockout of Tspo in mice does not affect retinal morphology, function and susceptibility to degeneration
errEXPERIMENTAL EYE RESEARCH
IF2.7
err2019-11-01
err12
errOAAI
errKlee, Katrin; Storti, Federica; Barben, Maya; Samardzija, Marijana; Langmann, Thomas; Dunaief, Joshua; Grimm, Christian
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Michael Weller
H-index: 175 · Papers: 2.8K
W
Wolfgang Wick
H-index: 142 · Papers: 1.6K
G
Guido Reifenberger
H-index: 136 · Papers: 1.2K
S
Stefan Zeuzem
H-index: 129 · Papers: 2.3K
E
Erwin F. Wagner
H-index: 127 · Papers: 512
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