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SaveShare Save Share Save Share Save Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice
Tse, E; Smith, AJH; Hunt, S; Lavenir, I; Forster, A; Warren, AJ; Grutz, G; Foroni, L; Carlton, MBL; Colledge, WH; Boehm, T; Rabbitts, TH Share Save Share Save Share Save Identification of a minority population of LMO2+ breast cancer cells that integrate into the vasculature and initiate metastasisSikandar, Shaheen S.; Gulati, Gunsagar S.; Antony, Jane; Fetter, Isobel; Kuo, Angera H.; Ho, William Hai Dang; Haro-Acosta, Veronica; Das, Soumyashree; Steen, Chloe B.; Pereira, Thiago Almeida; Qian, Dalong; Beachy, Philip A.; Dirbas, Fredrick; Red-Horse, Kristy; Rabbitts, Terence H.; Thiery, Jean Paul; Newman, Aaron M.; Clarke, Michael F. Share Save Share Save A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infectionMiller, Ami; Leach, Adam; Thomas, Jemima; McAndrew, Craig; Bentley, Emma; Mattiuzzo, Giada; John, Lijo; Mirazimi, Ali; Harris, Gemma; Gamage, Nadisha; Carr, Stephen; Ali, Hanif; Van Montfort, Rob; Rabbitts, Terence Share Save Share Save A cell-based screening method using an intracellular antibody for discovering small molecules targeting the translocation protein LMO2Bery, Nicolas; Bataille, Carole J. R.; Russell, Angela; Hayes, Angela; Raynaud, Florence; Milhas, Sabine; Anand, Sneha; Tulmin, Hanna; Miller, Ami; Rabbitts, Terence H. Share Save Salmonella-based platform for efficient delivery of functional binding proteins to the cytosolChabloz, Antoine; Schaefer, Jonas V.; Kozieradzki, Ivona; Cronin, Shane J. F.; Strebinger, Daniel; Macaluso, Francesca; Wald, Jiri; Rabbitts, Terence H.; Plueckthun, Andreas; Marlovits, Thomas C.; Penninger, Josef M. Share Save KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobeBery, Nicolas; Legg, Sandrine; Debreczeni, Judit; Breed, Jason; Embrey, Kevin; Stubbs, Christopher; Kolasinska-Zwierz, Paulina; Barrett, Nathalie; Marwood, Rose; Watson, Jo; Tart, Jon; Overman, Ross; Miller, Ami; Phillips, Christopher; MinterH, Ralph; Rabbitts, Terence H. Share Save Share Save Surfaceome interrogation using an RNA-seq approach highlights leukemia initiating cell biomarkers in an LMO2 T cell transgenic modelPais, Helio; Ruggero, Katia; Zhang, Jing; Al-Assar, Osama; Bery, Nicolas; Bhuller, Rayneet; Weston, Victoria; Kearns, Pamela R.; Mecucci, Cristina; Miller, Ami; Rabbitts, Terence H. Share Save Share Save Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compoundsCruz-Migoni, Abimael; Canning, Peter; Quevedo, Camilo E.; Bataille, Carole J. R.; Bery, Nicolas; Miller, Ami; Russell, Angela J.; Phillips, Simon E. V.; Carr, Stephen B.; Rabbitts, Terence H. Share Save Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragmentQuevedo, Camilo E.; Cruz-Migoni, Abimael; Bery, Nicolas; Miller, Ami; Tanaka, Tomoyuki; Petch, Donna; Bataille, Carole J. R.; Lee, Lydia Y. W.; Fallon, Phillip S.; Tulmin, Hanna; Ehebauer, Matthias T.; Fernandez-Fuentes, Narcis; Russell, Angela J.; Carr, Stephen B.; Phillips, Simon E. V.; Rabbitts, Terence H. Share Save BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions (vol 7, e37122, 2018)Bery, Nicolas; Cruz-Migoni, Abimael; Bataille, Carole J. R.; Quevedo, Camilo E.; Tulmin, Hanna; Miller, Ami; Russell, Angela; Phillips, Simon E. V.; Carr, Stephen B.; Rabbitts, Terence H. Share Save 
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