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SaveApelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice
Le Moal, Emmeran; Liu, Yuguo; Collerette-Tremblay, Jasmin; Dumontier, Simon; Fabre, Paul; Molina, Thomas; Dort, Junio; Orfi, Zakaria; Denault, Nicolas; Boutin, Joel; Michaud, Joris; Giguere, Hugo; Desroches, Alexandre; Tran, Kien; Ellezam, Benjamin; Vezina, Francois; Bedard, Sonia; Raynaud, Catherine; Balg, Frederic; Sarret, Philippe; Boudreault, Pierre-Luc; Scott, Michelle S.; Denault, Jean-Bernard; Marsault, Eric; Feige, Jerome N.; Auger-Messier, Mannix; Dumont, Nicolas A.; Bentzinger, C. Florian Share Save Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse ModelLapointe, Catherine; Vincent, Laurence; Giguere, Hugo; Auger-Messier, Mannix; Schwertani, Adel; Jin, Denan; Takai, Shinji; Pejler, Gunnar; Sirois, Martin G. G.; Tinel, Hanna; Heitmeier, Stefan; D'Orleans-Juste, Pedro Share Save Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac EffectsTran, Kien; Sainsily, Xavier; Cote, Jerome; Coquerel, David; Couvineau, Pierre; Saibi, Sabrina; Haroune, Lounes; Besserer-Offroy, Elie; Flynn-Robitaille, Joel; Rojas, Martin Resua; Murza, Alexandre; Longpre, Jean-Michel; Auger-Messier, Mannix; Lesur, Olivier; Bouvier, Michel; Marsault, Eric; Boudreault, Pierre-Luc; Sarret, Philippe Share Save Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patientsCoquerel, David; Lamoureux, Julie; Chagnon, Frederic; Tran, Kien; Sage, Michael; Fortin-Pellerin, Etienne; Delile, Eugenie; Sainsily, Xavier; Fournier, Justin; Dumont, Audrey-Ann; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric; Praud, Jean-Paul; Fulop, Tamas; Lesur, Olivier Share Save Share Save Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic ProfileTran, Kien; Van den Hauwe, Robin; Sainsily, Xavier; Couvineau, Pierre; Cote, Jerome; Simard, Louise; Echevarria, Marco; Murza, Alexandre; Serre, Alexandra; Theroux, Lea; Saibi, Sabrina; Haroune, Lounes; Longpre, Jean-Michel; Lesur, Olivier; Auger-Messier, Mannix; Spino, Claude; Bouvier, Michel; Sarret, Philippe; Ballet, Steven; Marsault, Eric Share Save Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin ReceptorTran, Kien; Murza, Alexandre; Sainsily, Xavier; Delile, Eugenie; Couvineau, Pierre; Cote, Jerome; Coquerel, David; Peloquin, Maude; Auger-Messier, Mannix; Bouvier, Michel; Lesur, Olivier; Sarret, Philippe; Marsault, Eric Share Save Share Save Share Save Share Save The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitmentBesserer-Offroy, Elie; Berube, Patrick; Cote, Jerome; Murza, Alexandre; Longpre, Jean-Michel; Dumaine, Robert; Lesur, Olivier; Auger-Messier, Mannix; Leduc, Richard; Marsault, Eric; Sarret, Philippe Share Save A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular EffectsTran, Kien; Murza, Alexandre; Sainsily, Xavier; Coquerel, David; Cote, Jerome; Belleville, Karine; Haroune, Lounes; Longpre, Jean-Michel; Dumaine, Robert; Salvail, Dany; Lesur, Olivier; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric Share Save Share Save ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic ShockCoquerel, David; Chagnon, Frederic; Sainsily, Xavier; Dumont, Lauralyne; Murza, Alexandre; Cote, Jerome; Dumaine, Robert; Sarret, Philippe; Marsault, Eric; Salvail, Dany; Auger-Messier, Mannix; Lesur, Olivier Share Save Share Save Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac FunctionsMurza, Alexandre; Sainsily, Xavier; Coquerel, David; Cote, Jerome; Marx, Patricia; Besserer-Offroy, Elie; Longpre, Jean-Michel; Laine, Jean; Reversade, Bruno; Salvail, Dany; Leduc, Richard; Dumaine, Robert; Lesur, Olivier; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric Share Save C-Terminal Modifications of Apelin-13 Significantly Change Ligand Binding, Receptor Signaling, and Hypotensive ActionMurza, Alexandre; Besserer-Offroy, Elie; Cote, Jerome; Berube, Patrick; Longpre, Jean-Michel; Dumaine, Robert; Lesur, Olivier; Auger-Messier, Mannix; Leduc, Richard; Sarret, Philippe; Marsault, Eric Share Save Share Save Share Save 
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