Thiruma V. Arumugam - Publications, H-index & Citations

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Thiruma V. Arumugam

sungkyunkwan university

77H-index

286Paper Count

2.1WCitation Count

Published Papers 138

Publication Date

HDAC6 regulates BACE1 stability and NLRP3 inflammasome activation in Alzheimer’s disease

Brain

IF11.7

2026-03-06

PREAI

Jeongmi Lee; Yongeun Cho; Bo Youn Choi; Hark Kyun Kim; Yeongyeong Lee; Eunae Kim; Jihoon Han; Jae Hoon Sul; Jun-Sik Kim; Seung Hyun Baek; Yoonsuk Cho; Jinsu Park; Gahee Bahn; Han-Gyu Bae; Jae Hyun Jun; Mitchell K P Lai; Thiruma V Arumugam; Dong-Gyu Jo

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Elevated serum inflammasome adaptor protein ASC is associated with white matter hyperintensities in vascular cognitive impairment

Brain Communications

IF4.5

2026-03-05

OAAI

Yuek Ling Chai; Saima Hilal; Vera Yuan Cai; Vincent C T Mok; Joyce R Chong; Yingqi Liao; Boon Yeow Tan; Narayanaswamy Venketasubramanian; Thiruma V Arumugam; Christopher Li-Hsian Chen; Mitchell K P Lai

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S100A8/A9 inhibition reduces splenic myelopoiesis and improves outcomes after stroke

Frontiers in Immunology

IF5.9

2026-02-17

OAAI

Hyun Ah Kim†; Annas Al-sharea†; Hannah X. Chu†; Sung-Chun Tang; Samoda A. Rupasinghe; Shenpeng R. Zhang; Prabhakara R. Nagareddy; Grant R. Drummond; Thiruma V. Arumugam; Andrew J. Murphy; Christopher G. Sobey; Man K.S. Lee

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Characterizing TDP-43 involvement in vascular dementia

alzheimer's & dementia

IF0

2026-02-14

OAAI

Marconi Fung; Yuek Ling Chai; Yi-Lin Cheng; Nishat Tabassum; Vernise J. T. Lim; Raj N. Kalaria; Dong-Gyu Jo; Christopher P. Chen; Mitchell K. P. Lai; Thiruma V. Arumugam

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Fyn-T Kinase Regulates DHA-Induced Pyroptosis in Immortalized Normal Human Astrocytes

Cells 2025, Vol. 14, Page 1530

IF5.2

2025-09-30

OAAI

Ai Ling Cheng; Yuek Ling Chai; Jasinda H. Lee; Clara Y. B. Low; Helen L. Ong; Gavin S. Dawe; Thiruma V. Arumugam; Deron R. Herr; Michelle G. K. Tan; Mitchell K. P. Lai

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Hypertension promotes neuroinflammation, brain injury and cognitive impairment

brain behavior and immunity

IF0

2025-07-10

PREAI

Quynh Nhu Dinh; Antony Vinh; Cecilia Lo; David E. Wong Zhang; Hericka Bruna Figueiredo Galvao; Sharmelee Selvaraji; Hyun Ah Kim; Sophocles Chrissobolis; Thiruma V. Arumugam; Grant R. Drummond; Christopher G. Sobey; T. Michael De Silva

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Hypoxia-mediated CRIP2 activation via NICD1 translocation regulates glycolysis and cell death

Genes & Diseases

IF9.4

2025-06-02

OAAI

Sunyoung Park; Sang-Ha Baik; Leon F. Palomera; Eunae Kim; Hark Kyun Kim; Jun-Sik Kim; Jong Ho Kim; Chanhee Kim; Thiruma V. Arumugam; Dong-Gyu Jo

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Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

GLIA

IF5.1

2025-05-26

OAAI

Kevin Jayaraj; Ritesh Kumar; Sukanya Shyamasundar; Thiruma V. Arumugam; Jai S. Polepalli; S. Thameem Dheen

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Unveiling the Therapeutic Promise of Epigenetics in Vascular Cognitive Impairment and Vascular Dementia

AGING AND DISEASE

IF6.9

2025-01-01

OAAI

Selvaraji, S; Mosberger, J; Fann, DY; Lai, MK; Chen, CLH; Arumugam, T

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Aging-associated sensory decline and Alzheimer's disease

MOLECULAR NEURODEGENERATION

IF17.5

2024-12-04

OAAI

Hong, Suji; Baek, Seung-Hyun; Lai, Mitchell K. P.; Arumugam, Thiruma V.; Jo, Dong-Gyu

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Circadian-Dependent Intermittent Fasting Influences Ischemic Tolerance and Dendritic Spine Remodeling

STROKE

IF8.9

2024-08-01

PREAI

Jeong, Soomin; Chokkalla, Anil K.; Davis, Charles K.; Jeong, Hyunmook; Chelluboina, Bharath; Arruri, Vijay; Kim, Bori; Narman, Ashlyn; Bathula, Saivenkateshkomal; Arumugam, Thiruma V.; Bendlin, Barbara B.; Vemuganti, Raghu

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Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

IF6.4

2024-07-16

OAAI

Seet, R. C. S.; Quek, A. M. L.; Teng, O.; Krishnan, S.; Ng, G. J. L.; Ng, M. Y.; Mahadevan, A.; Chioh, F. W. J.; Yeo, K. P.; Lim, H. Y.; Kim, J.; Swa, C. L. F.; Pek, N. M. Q.; Arumugam, T., V; Angeli, V; Gunaratne, J.; Cheung, C.

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Post-stroke cognitive impairment and brain hemorrhage are augmented in hypertensive mice

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2024-06-17

OAAI

Zhang, David E. Wong; Hughes, Tayla A. Gibson; Galvao, Hericka B. Figueiredo; Lo, Cecilia; Dinh, Quynh Nhu; Zhang, Shenpeng R.; Kim, Hyun Ah; Selvaraji, Sharmalee; Clarkson, Andrew N.; Arumugam, Thiruma, V; Drummond, Grant; Sobey, Christopher G.; De Silva, T. Michael

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Blood-based biomarkers of cerebral small vessel disease

AGEING RESEARCH REVIEWS

IF12.4

2024-03-01

OAAI

Wu, Liu-Yun; Chai, Yuek Ling; Cheah, Irwin K.; Chia, Rachel S. L.; Hilal, Saima; Arumugam, Thiruma V.; Chen, Christopher P.; Lai, Mitchell K. P.

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Human amnion epithelial cell therapy reduces hypertension-induced vascular stiffening and cognitive impairment

SCIENTIFIC REPORTS

IF3.9

2024-01-22

OAAI

Dinh, Quynh Nhu; Lo, Cecilia; Zhang, David Wong; Tran, Vivian; Gibson-Hughes, Tayla; Sheriff, Ashleigh; Diep, Henry; Kim, Hyun Ah; Zhang, Shenpeng R.; Barreto-Arce, Liz J.; Jelinic, Maria; Vinh, Antony; Arumugam, Thiruma V.; Chan, Siow Teng; Lim, Rebecca; Drummond, Grant R.; Sobey, Christopher G.; De Silva, T. Michael

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The Concise Guide to PHARMACOLOGY 2023/24: Introduction and Other Protein Targets

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2023-12-20

OAAI

Alexander, Stephen P. H.; Kelly, Eamonn; Mathie, Alistair A.; Peters, John A.; Veale, Emma L.; Armstrong, Jane F.; Buneman, O. Peter; Faccenda, Elena; Harding, Simon D.; Spedding, Michael; Cidlowski, John A.; Fabbro, Doriano; Davenport, Anthony P.; Striessnig, Joerg; Davies, Jamie A.; Ahlers-Dannen, Katelin E.; Alqinyah, Mohammed; Arumugam, Thiruma V.; Bodle, Christopher; Dagner, Josephine Buo; Chakravarti, Bandana; Choudhuri, Shreoshi P.; Druey, Kirk M.; Fisher, Rory A.; Gerber, Kyle J.; Hepler, John R.; Hooks, Shelley B.; Kantheti, Havish S.; Karaj, Behirda; Layeghi-Ghalehsoukhteh, Somayeh; Lee, Jae-Kyung; Luo, Zili; Martemyanov, Kirill; Mascarenhas, Luke D.; McNabb, Harrison; Montanez-Miranda, Carolina; Ogujiofor, Osita; Phan, Hoa; Roman, David L.; Shaw, Vincent; Sjogren, Benita; Sobey, Christopher; Spicer, Mackenzie M.; Squires, Katherine E.; Sutton, Laurie; Wendimu, Menbere; Wilkie, Thomas; Xie, Keqiang; Zhang, Qian; Zolghadri, Yalda

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The E3 ubiquitin ligase NEDD4 regulates chemoresistance to 5-fluorouracil in colorectal cancer cells by altering JNK signalling

CELL DEATH & DISEASE

IF9.6

2023-12-14

OAAI

Anand, Sushma; Nedeva, Christina; Chitti, Sai V.; Fonseka, Pamali; Kang, Taeyoung; Gangoda, Lahiru; Tabassum, Nishat I.; Abdirahman, Suad; Arumugam, Thiruma V.; Putoczki, Tracy L.; Kumar, Sharad; Mathivanan, Suresh

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Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer's disease and vascular dementia

ALZHEIMERS RESEARCH & THERAPY

IF7.6

2023-12-12

OAAI

Chua, Xin Ying; Torta, Federico; Chong, Joyce R.; Venketasubramanian, Narayanaswamy; Hilal, Saima; Wenk, Markus R.; Chen, Christopher P.; Arumugam, Thiruma V.; Herr, Deron R.; Lai, Mitchell K. P.

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Inflammasome Activation Mediates Apoptotic and Pyroptotic Death in Astrocytes Under Ischemic Conditions (vol 25, pg 533, 2023)

NEUROMOLECULAR MEDICINE

IF3.9

2023-09-21

OAAI

Wong, Lap Jack; Lee, Bernice Woon Li; Sng, Yi Jing; Poh, Luting; Rajeev, Vismitha; Selvaraji, Sharmelee; Drummond, Grant R.; Sobey, Christopher G.; Arumugam, Thiruma V.; Fann, David Y.

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Inflammasome Activation Mediates Apoptotic and Pyroptotic Death in Astrocytes Under Ischemic Conditions

NEUROMOLECULAR MEDICINE

IF3.9

2023-08-30

PREAI

Wong, Lap Jack; Lee, Bernice Woon Li; Sng, Yi Jing; Poh, Luting; Rajeev, Vismitha; Selvaraji, Sharmelee; Drummond, Grant R.; Sobey, Christopher G.; Arumugam, Thiruma V.; Fann, David Y.

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Research Directions