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SaveImmediate variations in high-dimensional circulating immune cells following pancreatectomy
Garnier, Jonathan; Palen, Anais; Durand, Xavier; Ewald, Jacques; Amara, Amira Ben; Rouviere, Marie Sarah; Granjeaud, Samuel; Bellan, Gregoire; Choisy, Benjamin; Verdonk, Franck; Gaudilliere, Brice; Gouarne, Caroline; Turrini, Olivier; Olive, Daniel; Chretien, Anne Sophie
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SaveBTN2A1 targeting reprograms M2-like macrophages and TAMs via SYK and MAPK signaling
Kerneur, Clement; Foucher, Etienne; Casas, Jaime Guillen; Colazet, Magali; Le, Kieu-Suong; Fullana, Marie; Bergot, Elise; Audemard, Corentin; Drapeau, Marion; Louche, Pauline; Gorvel, Laurent; Rouviere, Marie-Sarah; Boucherit, Nicolas; Audebert, Stephane; Magrini, Elena; Carnevale, Silvia; de Gassart, Aude; Madakamutil, Loui; Mantovani, Alberto; Garlanda, Cecilia; Agaugue, Sophie; Cano, Carla E.; Olive, Daniel
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SaveProtective role of macrophages from maternal-fetal interface in unvaccinated coronavirus disease 2019 pregnant women
Gay, Laetitia; Madariaga Zarza, Sandra; Abou Atmeh, Perla; Rouviere, Marie-Sarah; Andrieu, Jonatane; Richaud, Manon; Boumaza, Asma; Miquel, Laura; Diallo, Aissatou Bailo; Bechah, Yassina; Otmani Idrissi, Myriem; La Scola, Bernard; Olive, Daniel; Resseguier, Noemie; Bretelle, Florence; Mezouar, Soraya; Mege, Jean-Louis
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SaveVγ9Vδ2 T-cells Are Potent Inhibitors of SARS-CoV-2 Replication and Represent Effector Phenotypes in Patients With COVID-19
Gay, Laetitia; Rouviere, Marie-Sarah; Mezouar, Soraya; Richaud, Manon; Gorvel, Laurent; Foucher, Etienne; La Scola, Bernard; Menard, Amelie; Allardet-Servent, Jerome; Halfon, Philippe; Frohna, Paul; Cano, Carla; Mege, Jean-Louis; Olive, Daniel
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SavePreclinical characterization of ETx-22, a next-generation antibody drug conjugate (ADC) targeting nectin-4
Azim, Hatem; Lhospice, Florence; Preville, Xavier; Fares, Joanna; Lopez, Marc; Crompot, Emerence; Josselin, Emmanuelle; Castellano, Remy; Wehbeh, Maria; Collette, Yves; Elands, Jack; Olive, Daniel
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SaveActivation of γ9δ2 T cells by ICT01 as a novel immunotherapeutic approach for relapsed/refractory hematologic cancers (EVICTION trial)
Garciaz, S.; Champiat, S.; Peterlin, P.; Lemmens, K.; de Gassart, A.; Brune, P.; Valentin, E.; Leparquier, C.; Iche, M.; Olive, D.; Vey, N.; Frohna, P. A.
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SaveCD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer
Fattori, Stephane; Le Roy, Aude; Houacine, Jemila; Robert, Lucie; Abes, Riad; Gorvel, Laurent; Granjeaud, Samuel; Rouviere, Marie-Sarah; Ben Amara, Amira; Boucherit, Nicolas; Tarpin, Carole; Pakradouni, Jihane; Charafe-Jauffret, Emmanuelle; Houvenaeghel, Gilles; Lambaudie, Eric; Bertucci, Francois; Rochigneux, Philippe; Goncalves, Anthony; Foussat, Arnaud; Chretien, Anne-Sophie; Olive, Daniel
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SaveLow plasma PD-L1 levels, early tumor onset and absence of peritoneal carcinomatosis improve prognosis of women with advanced high-grade serous ovarian cancer
Fanale, Daniele; Brando, Chiara; Corsini, Lidia Rita; Cutaia, Sofia; Di Donna, Mariano Catello; Randazzo, Ugo; Filorizzo, Clarissa; Lisanti, Chiara; Magrin, Luigi; Gurrera, Vittorio; Romano, Raffaella; Dimino, Alessandra; Bazan Russo, Tancredi Didier; Olive, Daniel; Vieni, Salvatore; Pantuso, Gianni; Giordano, Antonio; Chiantera, Vito; Russo, Antonio; Bazan, Viviana; Iovanna, Juan Lucio
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SaveA non-inferiority randomized phase III trial of standard immunotherapy by checkpoint inhibitors vs. reduced dose intensity in responding patients with metastatic cancer: the MOIO protocol study
Gravis, Gwenaelle; Marino, Patricia; Olive, Daniel; Penault-LLorca, Frederique; Delord, Jean-Pierre; Simon, Clotilde; Lamrani-Ghaouti, Assia; Sabatier, Renaud; Ciccolini, Joseph; Boher, Jean-Marie
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SaveFirst-in-human study of ICT01, an anti-BTN3A activating monoclonal antibody in combination with low dose IL-2 in patients with advanced solid tumors (EVICTION-2 study)
de Bono, Johann; Champiat, Stephane; Danlos, Francois-Xavier; Wermke, Martin; Kunzmann, Volker; De Gassart, Aude; Valentin, Emmanuel; Iche, Marina; Mairesse, Maelle; Brune, Patrick; Lemmens, Katrien; Marabelle, Aurelien; Olive, Daniel; Frohna, Paul
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SaveSelective depletion of regulatory T cells by ALD2510, a novel IL-2-sparing anti-CD25 antibody, synergizes with PD-1 blockade in breast and gynecologic cancers
Fattori, Stephane; Le Roy, Aude; Houacine, Jemila; Robert, Lucie; Abes, Riad; Gorvel, Laurent; Granjeaud, Samuel; Rouviere, Marie-Sarah; Ben Amara, Amira; Boucherit, Nicolas; Tarpin, Carole; Pakradouni, Jihane; Charafe-Jauffret, Emmanuelle; Barrou, Julien; Houvenaeghel, Gilles; Lambaudie, Eric; Bertucci, Francois; Rochigneux, Philippe; Goncalves, Anthony; Foussat, Arnaud; Chretien, Anne-Sophie; Olive, Daniel
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SaveAnti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors
Gorvel, Laurent; Demerle, Clemence; Mello, Marielle; Pastor, Sonia; Degos, Clara; Zarubica, Ana; Angelis, Fabien; Fiore, Frederic; Nunes, Jacques; Malissen, Bernard; Greillier, Laurent; Guittard, Geoffrey; Luche, Herve; Barlesi, Fabrice; Olive, Daniel
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SavePreclinical development of ALD2510, a NextGen Fc-enhanced, TREG-selective and IL-2-sparing anti-CD25 antibody for the treatment of solid tumors
Houacine, Jemila; Abes, Riad; Marie-Cardine, Anne; Le Roy, Aude; Serbin, Bettina; Robert, Lucie; Giustiniani, Jerome; Chretien, Anne-Sophie; Fattori, Stephane; Gorvel, Laurent; Bensussan, Armand; Olive, Daniel; Foussat, Arnaud
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