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Sébastien J. Hotte

mcmaster university

51H-index
461Paper Count
9.9KCitation Count
Published Papers 93
Publication Date
Canagliflozin Is a Novel Androgen Receptor Pathway Inhibitor for Castrate-Sensitive and Castrate-Resistant Prostate Cancer
err2026-04-24
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PREAI
errAmr Ali; Fiorella Di Pastena; Olga-Demetra Biziotis; Simon Wang; Evangelia E. Tsakiridis; Daniel Del Rosso; James C. Fredenburgh; Jeffrey I. Weitz; Sebastien J. Hotte; Jonathan L. Bramson; Gregory R. Steinberg; Theodoros Tsakiridis
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Repertoire and clinical hierarchy of AR locus alterations in castration-resistant prostate cancer
err2025-10-27
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errOAAI
errT. Virtanen; E.M. Kwan; K. Parekh; J.V.W. Bacon; C.F. Huang; I.P.L. Yu; L. Ryyppö; C. Bernales; G. Donnellan; C. Tam; J. Sipola; J. Nikkola; G. Vandekerkhove; S.H. Tolmeijer; K. Kukkonen; null Adelia; B.J. Eigl; D. Finch; R. Gagnon; Y. Takieldeen; E. Hardy; D. Khalaf; C. Kollmannsberger; J.-M. Lavoie; C. Maurice-Dror; S. Miller; L. Nappi; K. Noonan; S. Parimi; A. Riminchan; E. Sartori-Mueller; M. Soleimani; J. Vergidis; M. Zulfiqar; A. Hansen; S. Hotte; M. Jafri; M. Kolinsky; S.D. Mukherjee; M. Ong; A.A.N. Rose; W. Tu; E. Winquist; A.M. Bergman; K. van der Zande; W. Zwart; N. Mehra; N.P. van Erp; J.L. Zhao; D. Rathkopf; C. Barbieri; D. Quigley; M. Nykter; N.A. Lack; K.N. Chi; M. Annala; A.W. Wyatt
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Phase I/II trial of oral masofaniten (EPI-7386) in combination with enzalutamide (Enz) compared to enz alone in metastatic castration-resistant prostate cancer (mCRPC) subjects
err2024-09-01
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PREAI
errKyriakopoulos, C.; Chatta, G.; Laccetti, A. L.; Iannotti, N.; Sokolova, A. O.; Hotte, S. J.; Tutrone, R.; Markowski, M. C.; Nordquist, L. T.; Pili, R.; Saad, F.; Zhang, J.; Villaluna, K.; Younginger, B.; Le Moigne, R.; Cesano, A.
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Final results: Randomized assessment of cisplatin dosing interval for ototoxicity (RADIO) trial comparing chemoradiation (CRT) with cisplatin q3weekly to weekly for locally advanced squamous cell carcinoma of the head and neck (LASCCHN)
err2024-09-01
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PREAI
errKuruvilla, M. S.; Meyers, B.; Smoragiewicz, M.; Stewart, P.; Ghedira, S.; Bordeleau, L.; Chan, K. K.; Hotte, S. J.; Parker, C.; Palma, D.; Kim, D-H.; Karam, I.; Lang, P.; Read, N.; Venkatesan, V.; Nichols, A.; Louie, A. V.; Kim, R.; Pond, G.; Winquist, E.
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Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients with Metastatic Urothelial Carcinoma
err2023-10-20
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errOAAI
errPetrylak, Daniel P.; Eigl, Bernhard J.; George, Saby; Heath, Elisabeth I.; Hotte, Sebastien J.; Chism, David D.; Nabell, Lisle M.; Picus, Joel; Cheng, Susanna Y.; Appleman, Leonard J.; Sonpavde, Guru P.; Morgans, Alicia K.; Pourhosseini, Pourya; Wu, Ruishan; Standley, Laura; Croitoru, Ruslan; Yu, Evan Y.
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Phase I/II trial of oral EPI-7386 in combination with enzalutamide (enz) compared to enz alone in metastatic castration-resistant prostate cancer (mCRPC) subjects: Current phase I (PI) results
err2023-10-01
err1
PREAI
errLaccetti, A. L.; Chatta, G.; Kyriakopoulos, C.; Iannotti, N.; Hotte, S. J.; Markowski, M. C.; Pili, R.; Vuky, J.; Zhang, J.; Saad, F.; Villaluna, K.; Younginger, B.; Le Moigne, R.; Cesano, A.
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Discrete-Choice Experiment to Understand the Preferences of Patients with Hormone-Sensitive Prostate Cancer in the USA, Canada, and the UK
err2023-08-11
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errOAAI
errGonzalez, Juan Marcos; Ganguli, Arijit; Morgans, Alicia K. K.; Tombal, Bertrand F. F.; Hotte, Sebastien J. J.; Suzuki, Hiroyoshi; Bhadauria, Hemant; Oh, Mok; Scales Jr, Charles D. D.; Wallace, Matthew J. J.; Yang, Jui-Chen; George, Daniel J. J.
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Use of Systemic Therapies for Treatment of Psoriasis in Patients with a History of Treated Solid Tumours: Inference-Based Guidance from a Multidisciplinary Expert Panel (vol 13, pg 867, 2023)
err2023-07-06
err1
errOAAI
errPapp, Kim A.; Melosky, Barbara; Sehdev, Sandeep; Hotte, Sebastien J.; Beecker, Jennifer R.; Kirchhof, Mark G.; Turchin, Irina; Dutz, Jan P.; Gooderham, Melinda J.; Gniadecki, Robert; Hong, Chih-ho; Lambert, Jo; Lynde, Charles W.; Prajapati, Vimal H.; Vender, Ronald B.
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Use of Systemic Therapies for Treatment of Psoriasis in Patients with a History of Treated Solid Tumours: Inference-Based Guidance from a Multidisciplinary Expert Panel
err2023-03-16
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errOAAI
errPapp, Kim A.; Melosky, Barbara; Sehdev, Sandeep; Hotte, Sebastien J.; Beecker, Jennifer R.; Kirchhof, Mark G.; Turchin, Irina; Dutz, Jan P.; Gooderham, Melinda J.; Gniadecki, Robert; Hong, Chih-ho; Lambert, Jo; Lynde, Charles W.; Prajapati, Vimal H.; Vender, Ronald B.
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FRACTION-RCC: nivolumab plus ipilimumab for advanced renal cell carcinoma after progression on immuno-oncology therapy
err2022-11-03
err19
errOAAI
errChoueiri, Toni K.; Kluger, Harriet; George, Saby; Tykodi, Scott S.; Kuzel, Timothy M.; Perets, Ruth; Nair, Suresh; Procopio, Giuseppe; Carducci, Michael A.; Castonguay, Vincent; Folefac, Edmund; Lee, Chung-Han; Hotte, Sebastien J.; Miller, Wilson H.; Saggi, Shruti Shally; Lee, Chung-Wei; Desilva, Heshani; Bhagavatheeswaran, Prabhu; Motzer, Robert J.; Escudier, Bernard
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Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA
err2022-11-01
err21
errOAAI
errMatsubara, Nobuaki; de Bono, Johann; Olmos, David; Procopio, Giuseppe; Kawakami, Satoru; Urun, Yuksel; van Alphen, Robbert; Flechon, Aude; Carducci, Michael A.; Choi, Young Deuk; Hotte, Sebastien J.; Korbenfeld, Ernesto; Kramer, Gero; Agarwal, Neeraj; Chi, Kim N.; Dearden, Simon; Gresty, Christopher; Kang, Jinyu; Poehlein, Christian; Harrington, Elizabeth A.; Hussain, Maha
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Outcomes of Cytoreductive Nephrectomy for Patients with Metastatic Renal Cell Carcinoma: Real World Data from Canadian Centers
err2022-11-01
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PREAI
errDragomir, Alice; Nazha, Sara; Tanguay, Simon; Breau, Rodney H.; Bhindi, Bimal; Rendon, Ricardo A.; Kapoor, Anil; Hotte, Sebastien J.; Basappa, Naveen; Fairey, Adrian; So, Alan I.; Kollmannsberger, Christian; Finelli, Antonio; Hansen, Aaron; Canil, Christina; Heng, Daniel; Lattouf, Jean-Baptiste; Bjarnason, Georg; Power, Nicholas; Pouliot, Frederic; Wood, Lori A.
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4-factor model to predict response and survival benefit with durvalumab (D) in previously treated metastatic urinary tract carcinoma (mUTC)
err2022-09-01
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errOAAI
errSonpavde, G. P.; Sternberg, C. N.; Lee, J-L.; Emeribe, U.; Oh, S. M.; De Lima, A. R. Dantas; Hotte, S. J.
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Outcomes of patients with advanced non-clear cell renal cell carcinoma treated with first-line immune checkpoint inhibitor therapy
err2022-08-01
err24
PREAI
errGraham, Jeffrey; Wells, John Connor; Dudani, Shaan; Gan, Chun L.; Donskov, Frede; Lee, Jae-Lyun; Kollmannsberger, Christian K.; Meza, Luis; Beuselinck, Benoit; Hansen, Aaron; North, Scott A.; Bjarnason, Georg A.; Sayegh, Nicolas; Kanesvaran, Ravindran; Wood, Lori A.; Hotte, Sebastien J.; McKay, Rana R.; Choueiri, Toni K.; Heng, Daniel Y. C.
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Primary results of STRONG: An open-label, multicenter, phase 3b study of fixed-dose durvalumab monotherapy in previously treated patients with urinary tract carcinoma
err2022-03-01
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errOAAI
errSonpavde, Guru P.; Sternberg, Cora N.; Loriot, Yohann; Marabelle, Aurelien; Lee, Jae Lyun; Flechon, Aude; Roubaud, Guilhem; Pouessel, Damien; Zagonel, Vittorina; Calabro, Fabio; Banna, Giuseppe L.; Shin, Sang Joon; Vera-Badillo, Francisco E.; Powles, Thomas; Hellmis, Eva; Miranda, Paulo A. P.; Lima, Ana Rita; Emeribe, Ugochi; Oh, Sun Min; Hotte, Sebastien J.
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Real-world utilization and outcomes of docetaxel among older men with metastatic prostate cancer: a retrospective population-based cohort study in Canada
err2022-02-23
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PREAI
errShayegan, Bobby; Wallis, Christopher J. D.; Hamilton, Robert J.; Morgan, Scott C.; Cagiannos, Ilinas; Basappa, Naveen S.; Ferrario, Cristiano; Gotto, Geoffrey T.; Fernandes, Ricardo; Roy, Soumyajit; Noonan, Krista L.; Niazi, Tamim; Hotte, Sebastien J.; Saad, Fred; Hew, Huong; Park-Wyllie, Laura; Chan, Katherine F. Y.; Malone, Shawn
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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction
err2022-02-07
err6
errOAAI
errVoon, Pei Jye; Chen, Eric X.; Chen, Helen X.; Lockhart, Albert C.; Sahebjam, Solmaz; Kelly, Karen; Vaishampayan, Ulka N.; Subbiah, Vivek; Razak, Albiruni R.; Renouf, Daniel J.; Hotte, Sebastien J.; Singh, Arti; Bedard, Philippe L.; Hansen, Aaron R.; Ivy, S. Percy; Wang, Lisa; Stayner, Lee-Anne; Siu, Lillian L.; Spreafico, Anna
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A phase 1 pharmacokinetic trial of single agent trametinib a MEK inhibitor in advanced cancer patients with hepatic dysfunction: An NCI Organ Dysfunction Working Group (ODWG) study (NCI 9591)
err2021-12-01
err1
PREAI
errVoon, Pei Jye; Chen, Eric X.; Chen, Helen X.; Lockhart, Albert C.; Sahebjam, Solmaz; Kelly, Karen; Vaishampayan, Ulka N.; Subbiah, Vivek; Razak, Albiruni R.; Renouf, Daniel J.; Hotte, Sebastien J.; Singh, Arti; Bedard, Philippe L.; Hansen, Aaron R.; Percy, Ivy S.; Wang, Lisa; Stayner, Lee-Anne; Siu, Lillian L.; Spreafico, Anna
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Real-World Use of Androgen-Deprivation Therapy: Intensification Among Older Canadian Men With de Novo Metastatic Prostate Cancer
err2021-10-01
err32
errOAAI
errWallis, Christopher J. D.; Malone, Shawn; Cagiannos, Ilias; Morgan, Scott C.; Hamilton, Robert J.; Basappa, Naveen S.; Ferrario, Cristiano; Gotto, Geoffrey T.; Fernandes, Ricardo; Niazi, Tamim; Noonan, Krista L.; Saad, Fred; Hotte, Sebastien J.; Hew, Huong; Chan, Katherine F. Y.; Wyllie, Laura Park; Shayegan, Bobby
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