Not logged in A Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC) Aroldi, Francesca; Elez, Elena; Andre, Thierry; Perkins, Geraldine; Prenen, Hans; Popovici, Vlad; Gallagher, Peter; Houlden, Jennifer; Collins, Linda; Roberts, Corran; Rolfo, Christian; Di Nicolantonio, Federica; Grayson, Margaret; Boyd, Ruth; Bettens, Karolien; Delfavero, Jurgen; Coyle, Victoria; Lawler, Mark; Khawaja, Hajrah; Laurent-Puig, Pierre; Salto-Tellez, Manuel; Maughan, Tim S.; Tabernero, Josep; Adams, Richard; Jones, Robert; Hennessy, Bryan T.; Bardelli, Alberto; Peeters, Marc; Middleton, Mark R.; Wilson, Richard H.; Van Schaeybroeck, Sandra Share Save
A phase I open-label, dose-escalation study of NUC-3373, a targeted thymidylate synthase inhibitor, in patients with advanced cancer (NuTide:301) Spiliopoulou, Pavlina; Kazmi, Farasat; Aroldi, Francesca; Holmes, Thomas; Thompson, David; Griffiths, Lucinda; Qi, Cathy; Parkes, Matthew; Lord, Simon; Veal, Gareth J.; Harrison, David J.; Coyle, Vicky M.; Graham, Jill; Jeffry Evans, Thomas R.; Blagden, Sarah P. Share Save
Preliminary efficacy and safety of rilvegostomig (AZD2936), a bispecific antibody targeting PD-1 and TIGIT, in checkpoint inhibitor (CPI)-pretreated advanced/metastatic non-smallcell lung cancer (NSCLC): ARTEMIDE-01 Brandao, M.; Hiltermann, J. T. J. N.; Wauters, E.; Solomon, B. J.; Alvarez, E. Castanon; Felip, E.; Gort, E. H.; Izumi, H.; Kim, D-W.; Paz-Ares, L.; Rohrberg, K. S.; Steinbusch, L.; Yoshida, T.; Chen, H.; Colebrook, S.; Achour, I.; Origuchi, M.; Aroldi, F.; Cho, B. C. Share Save
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IGNYTE: AN OPEN-LABEL, MULTICENTER, PHASE 1/2 (PH 1/2) CLINICAL TRIAL OF RP1 ± NIVOLUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS Middleton, Mark; Milhem, Mohammed; Aroldi, Francesca; Sacco, Joseph; VanderWalde, Ari; Baum, Scott; Samson, Adel; Chesney, Jason; Niu, Jiaxin; Rhodes, Terence; Bowles, Tawnya; Emamekhoo, Hamid; Tsai, Katy; In, Gino; Beasley, Georgia; Chmielowski, Bartosz; Dalac-Rat, Sophie; Kahler, Katharina; Munoz, Eva; Olsson-Brown, Anna; Bommareddy, Praveen; Menezes, Lavita; Pirzkall, Andrea; Coffin, Robert; Harrington, Kevin Share Save
A first-in-human study of NUC-7738, a ProTide transformation of 3′-deoxyadenosine, in patients with advanced solid tumours (NuTide:701) Blagden, S.; Haris, N. M.; Boh, Z.; Kazmi, F.; Aroldi, F.; Myers, M.; Symeonides, S. N.; Plummer, R. Share Save
Results of a first-in-human study of the ProTide thymidylate synthase inhibitor NUC-3373, in patients with advanced solid tumours (NuTide:301) Spiliopoulou, P.; Kazmi, F.; Aroldi, F.; Holmes, J.; Graham, J.; Holmes, T.; Lord, S.; Veal, G.; Qi, C.; Coyle, V. M.; Evans, T. R. J.; Blagden, S. Share Save
An open-label, multicenter, phase I/II clinical trial of RP1 as a single agent and in combination with nivolumab in patients with solid tumors [IGNYTE] Aroldi, F.; Middleton, M. R.; Sacco, J. J.; Milhem, M. M.; Curti, B. D.; VanderWalde, A. M.; Baum, S. L.; Samson, A.; Chesney, J.; Niu, J.; Rhodes, T. D.; Bowles, T. L.; Olsson-Brown, A.; Laux, D. E.; Bommareddy, P. K.; Menezes, L.; Samakoglu, S.; Pirzkall, A.; Coffin, R. S.; Harrington, K. J. Share Save
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Inhibition of thymidylate synthase by the ProTide NUC-3373: in vitro analysis and clinical validation Blagden, Sarah P.; McKissock, Fiona G.; Graham, Janet S.; Ciombor, Kristen K.; Aroldi, Francesca; Rodgers, Lisa J.; Myers, Michelle; Berlin, Jordan; Evans, T. R. Jeffry; Harrison, David J. Share Save
Metformin Use Is Associated With Longer Progression-Free Survival of Patients With Diabetes and Pancreatic Neuroendocrine Tumors Receiving Everolimus and/or Somatostatin Analogues Pusceddu, Sara; Vernieri, Claudio; Di Maio, Massimo; Marconcini, Riccardo; Spada, Francesca; Massironi, Sara; Ibrahim, Toni; Brizzi, Maria Pia; Campana, Davide; Faggiano, Antongiulio; Giuffrida, Dario; Rinzivillo, Maria; Cingarlini, Sara; Aroldi, Francesca; Antonuzzo, Lorenzo; Berardi, Rossana; Catena, Laura; De Divitiis, Chiara; Ermacora, Paola; Perfetti, Vittorio; Fontana, Annalisa; Razzore, Paola; Carnaghi, Carlo; Davi, Maria Vittoria; Cauchi, Carolina; Duro, Marilina; Ricci, Sergio; Fazio, Nicola; Cavalcoli, Federica; Bongiovanni, Alberto; La Salvia, Anna; Brighi, Nicole; Colao, Annamaria; Puliafito, Ivana; Panzuto, Francesco; Ortolani, Silvia; Zaniboni, Alberto; Di Costanzo, Francesco; Torniai, Mariangela; Bajetta, Emilio; Tafuto, Salvatore; Garattini, Silvio Ken; Femia, Daniela; Prinzi, Natalie; Concas, Laura; Lo Russo, Giuseppe; Milione, Massimo; Giacomelli, Luca; Buzzoni, Roberto; Delle Fave, Gianfranco; Mazzaferro, Vincenzo; de Braud, Filippo Share Save
Impact of metformin on progression-free survival in diabetic patients with advanced pancreatic neuroendocrine tumors (pNETs) receiving everolimus and/or somatostatin analogues: A sensitivity analysis of the PRIME-NET (pancreatic multicentric, retrospective, italian metformin) study Pusceddu, Sara; Vernieri, Claudio; Di Maio, Massimo; Daniela, Femia; Prinzi, Natalie; Marconcini, Riccardo; Spada, Francesca; Massironi, Sara; Bongiovanni, Alberto; Brizzi, Maria Pia; Campana, Davide; Faggiano, Antongiulio; Giuffrida, Dario; Delle Fave, Gianfranco; Cingarlini, Sara; Aroldi, Francesca; Antonuzzo, Lorenzo; Berardi, Rossana; Catena, Laura; Buzzoni, Roberto; de Braud, Filippo Share Save
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