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D

Daniel B. Lipka

dkfz and heidelberg university hospital

39H-index
225Paper Count
6.0KCitation Count
Published Papers 71
Publication Date
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Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor
errNature Communications
IF15.7
err2026-04-09
err0
errOAAI
errMarcus Renner; Małgorzata Oleś; Nagarajan Paramasivam; Christoph E. Heilig; Annika Schneider; Caroline Modugno; Catherine Herremans; Jennifer Hüllein; Barbara Hutter; Cihan Erkut; Andreas Mock; Eva Krieghoff-Henning; Cecilia B. Jensen; Amirhossein Sakhteman; Matthew The; Tony Prinz; Panna Lajer; Annika Baude-Müller; Katja Beck; Bettina Beuthien-Baumann; Leonidas Apostolidis; Sebastian Bauer; Melanie Boerries; Christian H. Brandts; Damian T. Rieke; Thomas Kindler; Frederick Klauschen; Klaus Schulze-Osthoff; Richard F. Schlenk; Guy Berchem; Michael Allgäuer; Gunhild Mechtersheimer; Albrecht Stenzinger; Daniel B. Lipka; Matthias Schlesner; Bernhard Kuster; Arne Jahn; Evelin Schröck; Christoph Heining; Maria-Veronica Teleanu; Peter Horak; Simon Kreutzfeldt; Daniel Hübschmann; Wolfgang Hartmann; Hanno Glimm; Stefan Fröhling
errShare
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The Knowledge Connector decision support system for multiomics-based precision oncology
errNature Communications
IF15.7
err2026-01-19
err0
errOAAI
errDaniel Hübschmann; Simon Kreutzfeldt; Benjamin Roth; Katrin Glocker; Janine Schoop; Lena Oeser; Steffen Hausmann; Christian Koch; Sebastian Uhrig; Jennifer Hüllein; Barbara Hutter; Martina Fröhlich; Christoph E. Heilig; Maria-Veronica Teleanu; Daniel B. Lipka; Irina A. Kerle; Annika Baude-Müller; Katja Beck; Christoph Heining; Hanno Glimm; Frank Ückert; Alexander Knurr; Stefan Fröhling; Peter Horak
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errSave
COMPREHENSIVE CHARACTERIZATION OF SOMATIC PTPN11-MUTATED JMML
errEJC Paediatric Oncology
IF0
err2025-11-01
err0
errOAAI
errMuratore, Edoardo; De Haas, Valerie; Bresters, Dorine; Flotho, Christian; Goncalves, Pierre; Hofmans, Mattias; Kavcic, Marko; Lammens, Tim; Lipka, Daniel B.; Petrikkos, Loizos; Niemeyer, Charlotte M.; Ramamoorthy, Senthilkumar; Lebrecht, Dirk; Masetti, Riccardo; Schonung, Maximilian
errShare
errSave
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-10-28
err0
errOAAI
errLin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo
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errSave
Assessment of peripheral blood DNA methylation signatures as pharmacodynamic and predictive biomarkers during azacitidine therapy in juvenile myelomonocytic leukaemia: Results of the EWOG-MESRAT study
errBritish Journal of Haematology
IF3.8
err2025-07-31
err0
errOAAI
errMaximilian Schönung; Silvia Rathmann; Senthilkumar Ramamoorthy; Dirk Lebrecht; Thomas Klingebiel; Franco Locatelli; Karsten Nysom; Claudia Rossig; Jan Starý; Marco Zecca; Meera Patturajan; Miriam Erlacher; Brigitte Strahm; Charlotte M. Niemeyer; Daniel B. Lipka; Christian Flotho
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errSave
DNA demethylation-mediated downregulation of MNX1 in acute myeloid leukemia
errLeukemia
IF13.4
err2025-07-14
err0
errOAAI
errSimge Kelekçi; Katherine Kelly; Ashish Goyal; Nick Wehrwein; Anna Riedel; Dieter Weichenhan; Michael Scherer; Birgitta E. Michels; Cindy Körner; Irene Orzella; Mariam Hakobyan; Marion Bähr; Elena Everatt; James Dunford; Daniel B. Lipka; Pavlo Lutsik; Udo Oppermann; Christoph Plass
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errSave
Clec12a is required for the pathogenesis of NUP98::NSD1 AML
errBlood Advances
IF7.1
err2025-05-09
err0
errOAAI
errSagarajit Mohanty; Fiorella Charles Cano; Razif Gabdoulline; Courteney K. Lai; Basem Othman; Harish Sudarsanam; Thomas Eder; Florian Grebien; Daniel B. Lipka; Reinhard Henschler; Michael Heuser
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errSave
Comprehensive genomic and transcriptomic analysis enables molecularly guided therapy options in peritoneal and pleural mesothelioma
errESMO OPEN
IF8.3
err2025-04-01
err0
errOAAI
errMoehrmann, L.; Werner, M.; Oles, M.; Knol, L.; Arnold, J. S.; Mundt, T.; Paramasivam, N.; Richter, D.; Froehlich, M.; Hutter, B.; Huellein, J.; Jahn, A.; Scheffold, C.; Moehrmann, E. E.; Hanf, D.; Kreutzfeldt, S.; Heilig, C. E.; Teleanu, M. -, V; Lipka, D. B.; Beck, K.; Baude-Muelle, A.; Jelas, I.; Rieke, D. T.; Klotz, L., V; Shah, R.; Herold, T.; Boerries, M.; Illert, A. L.; Allgaeuer, M.; Stenzinger, A.; Kerle, I. A.; Horak, P.; Heining, C.; Schroeck, E.; Huebschmann, D.; Froehling, S.; Glimm, H.
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errSave
Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)
errBLOOD ADVANCES
IF7.1
err2024-09-27
err1
errOAAI
errWeichenhan, Dieter; Riedel, Anna; Sollier, Etienne; Toprak, Umut H.; Hey, Joschka; Breuer, Kersten; Wierzbinska, Justyna A.; Touzart, Aurore; Lutsik, Pavlo; Baehr, Marion; Ostlund, Anders; Nilsson, Tina; Jacobsson, Susanna; Edler, Marcel; Waraky, Ahmed; Behrens, Yvonne Lisa; Goehring, Gudrun; Schlegelberger, Brigitte; Steinek, Clemens; Harz, Hartmann; Leonhardt, Heinrich; Dolnik, Anna; Reinhardt, Dirk; Bullinger, Lars; Palmqvist, Lars; Lipka, Daniel B.; Plass, Christoph
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errSave
Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia
errJOURNAL OF HEMATOLOGY & ONCOLOGY
IF40.4
err2024-06-09
err1
errOAAI
errHaage, Tobias Ronny; Charakopoulos, Emmanouil; Bhuria, Vikas; Baldauf, Conny K.; Korthals, Mark; Handschuh, Juliane; Mueller, Peter; Li, Juan; Harit, Kunjan; Nishanth, Gopala; Frey, Stephanie; Boettcher, Martin; Fischer, Klaus-Dieter; Dudeck, Jan; Dudeck, Anne; Lipka, Daniel B.; Schraven, Burkhart; Green, Anthony R.; Mueller, Andreas J.; Mougiakakos, Dimitrios; Fischer, Thomas
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errSave
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions
errNATURE COMMUNICATIONS
IF15.7
err2024-01-02
err3
errOAAI
errSchoepf, Julia; Uhrig, Sebastian; Heilig, Christoph E.; Lee, Kwang-Seok; Walther, Tatjana; Carazzato, Alexander; Dobberkau, Anna Maria; Weichenhan, Dieter; Plass, Christoph; Hartmann, Mark; Diwan, Gaurav D.; Carrero, Zunamys, I; Ball, Claudia R.; Hohl, Tobias; Kindler, Thomas; Rudolph-Haehnel, Patricia; Helm, Dominic; Schneider, Martin; Nilsson, Anna; Ora, Ingrid; Imle, Roland; Banito, Ana; Russell, Robert B.; Jones, Barbara C.; Lipka, Daniel B.; Glimm, Hanno; Huebschmann, Daniel; Hartmann, Wolfgang; Froehling, Stefan; Scholl, Claudia
errShare
errSave
NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology
errNPJ PRECISION ONCOLOGY
IF8
err2023-10-26
err7
errOAAI
errMock, Andreas; Teleanu, Maria-Veronica; Kreutzfeldt, Simon; Heilig, Christoph E.; Huellein, Jennifer; Moehrmann, Lino; Jahn, Arne; Hanf, Dorothea; Kerle, Irina A.; Singh, Hans Martin; Hutter, Barbara; Uhrig, Sebastian; Froehlich, Martina; Neumann, Olaf; Hartig, Andreas; Brueckmann, Sascha; Hirsch, Steffen; Grund, Kerstin; Dikow, Nicola; Lipka, Daniel B.; Renner, Marcus; Bhatti, Irfan Ahmed; Apostolidis, Leonidas; Schlenk, Richard F.; Schaaf, Christian P.; Stenzinger, Albrecht; Schroeck, Evelin; Huebschmann, Daniel; Heining, Christoph; Horak, Peter; Glimm, Hanno; Froehling, Stefan
errShare
errSave
Targeted therapy of desmoplastic small round cell tumor guided by multilayered molecular profiling
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err0
errOAAI
errRenner, M.; Oles, M.; Paramasivam, N.; Schneider, A.; Heilig, C. E.; Modugno, C.; Herremans, C.; Mock, A.; Lipka, D.; Bauer, S.; Kindler, T.; Brandts, C. H.; Keilholz, U.; Boerries, M.; Kuster, B.; Huebschmann, D.; Schlesner, M.; Glimm, H.; Schlenk, R. F.; Froehling, S.
errShare
errSave
Value of broad molecular profiling for cancer diagnosis
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err0
errOAAI
errWerstein, L. V. A.; Heilig, C. E.; Teleanu, M-V.; Huellein, J.; Singh, M.; Bauer, S.; Kindler, T.; Klauschen, F.; Brandts, C. H.; Rieke, D. T.; Illert, L.; Boerries, M.; Kreutzfeldt, S.; Horak, P.; Huebschmann, D.; Lipka, D. B.; Glimm, H.; Hartmann, W.; Froehling, S.
errShare
errSave
Genomics-based personalized oncology of advanced thymic epithelial tumors
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errMohrmann, Lino; Rostock, Lysann; Oles, Malgorzata; Jahn, Arne; Arlt, Marie; Paramasivam, Nagarajan; Johrens, Korinna; Rupp, Luise; Schmitz, Marc; Richter, Daniela; Uhrig, Sebastian; Frohlich, Martina; Hutter, Barbara; Hullein, Jennifer; Wolf, Elena E.; Hanf, Dorothea; Gieldon, Laura; Kreutzfeldt, Simon; Heilig, Christoph E.; Teleanu, Veronica; Lipka, Daniel B.; Mock, Andreas; Jelas, Ivan; Rieke, Damian T.; Wiesweg, Marcel; Boerries, Melanie; Illert, Anna L.; Desuki, Alexander; Kindler, Thomas; Krackhardt, Angela M.; Westphalen, C. Benedikt; Grosch, Heidrun; Apostolidis, Leonidas; Stenzinger, Albrecht; Kerle, Irina A.; Heining, Christoph; Hubschmann, Daniel; Schrock, Evelin; Frohling, Stefan; Glimm, Hanno
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errSave
Genomic, transcriptomic, functional, and mechanistic characterization of rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusions
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errSchoepf, Julia; Uhrig, Sebastian; Heilig, Christoph E.; Lee, Kwang-Seok; Walther, Tatjana; Carazzato, Alexander; Dobberkau, Anna Maria; Weichenhan, Dieter; Plass, Christoph; Hartmann, Mark; Diwan, Gaurav; Carrero, Zunamys; Ball, Claudia R.; Hohl, Tobias; Kindler, Thomas; Rudolph-Hahnel, Patricia; Nilsson, Anna; Ora, Ingrid; Imle, Roland; Banito, Ana; Russell, Robert; Jones, Barbara C.; Lipka, Daniel B.; Glimm, Hanno; Hubschmann, Daniel; Hartmann, Wolfgang; Frohling, Stefan; Scholl, Claudia
errShare
errSave
Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking
errLEUKEMIA
IF13.4
err2023-03-22
err5
errOAAI
errWeichenhan, Dieter; Riedel, Anna; Meinen, Charlotte; Basic, Alisa; Toth, Reka; Baehr, Marion; Lutsik, Pavlo; Hey, Joschka; Sollier, Etienne; Toprak, Umut H.; Kelekci, Simge; Lin, Yu-Yu; Hakobyan, Mariam; Touzart, Aurore; Goyal, Ashish; Wierzbinska, Justyna A.; Schlesner, Matthias; Westermann, Frank; Lipka, Daniel B.; Plass, Christoph
errShare
errSave
DNA methylation landscape of tumor-associated macrophages reveals pathways, transcription factors and prognostic value relevant to triple-negative breast cancer patients
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2022-12-09
err13
errOAAI
errHey, Joschka; Halperin, Coral; Hartmann, Mark; Mayer, Shimrit; Schoenung, Maximilian; Lipka, Daniel B.; Scherz-Shouval, Ruth; Plass, Christoph
errShare
errSave
DNA methylation biomarkers for noninvasive detection of triple-negative breast cancer using liquid biopsy
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2022-11-08
err24
errOAAI
errManoochehri, Mehdi; Borhani, Nasim; Gerhaeuser, Clarissa; Assenov, Yassen; Schoenung, Maximilian; Hielscher, Thomas; Christensen, Brock C.; Lee, Min Kyung; Grone, Hermann-Josef; Lipka, Daniel B.; Bruening, Thomas; Brauch, Hiltrud; Ko, Yon-Dschun; Hamann, Ute
errShare
errSave
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers
errANNALS OF ONCOLOGY
IF65.4
err2022-11-01
err28
errOAAI
errJahn, A.; Rump, A.; Widmann, T. J.; Heining, C.; Horak, P.; Hutter, B.; Paramasivam, N.; Uhrig, S.; Gieldon, L.; Drukewitz, S.; Kuebler, A.; Bermudez, M.; Hackmann, K.; Porrmann, J.; Wagner, J.; Arlt, M.; Franke, M.; Fischer, J.; Kowalzyk, Z.; William, D.; Weth, V.; Oster, S.; Froehlich, M.; Huellein, J.; Gonzalez, C. Valle; Kreutzfeldt, S.; Mock, A.; Heilig, C. E.; Lipka, D. B.; Moehrmann, L.; Hanf, D.; Oles, M.; Teleanu, V.; Allgaeuer, M.; Ruhnke, L.; Kutz, O.; Knurr, A.; Lassmann, A.; Endris, V.; Neumann, O.; Penzel, R.; Beck, K.; Richter, D.; Winter, U.; Wolf, S.; Pfuetze, K.; Geoerg, C.; Meissburger, B.; Buchhalter, I.; Augustin, M.; Aulitzky, W. E.; Hohenberger, P.; Kroiss, M.; Schirmacher, P.; Schlenk, R. F.; Keilholz, U.; Klauschen, F.; Folprecht, G.; Bauer, S.; Siveke, J. T.; Brandts, C. H.; Kindler, T.; Boerries, M.; Illert, A. L.; von Bubnoff, N.; Jost, P. J.; Metzeler, K. H.; Bitzer, M.; Schulze-Osthoff, K.; von Kalle, C.; Brors, B.; Stenzinger, A.; Weichert, W.; Huebschmann, D.; Froehling, S.; Glimm, H.; Schroeck, E.; Klink, B.
errShare
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Research Directions

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Co-authors
Cooperation Journals
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