Not logged in Genetic and immune landscape evolution in MMR-deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Fong, Caroline; Barber, Louise J.; Anandappa, Gayathri; Crux, Richard; Assiotis, Ioannis; Fenwick, Kerry; Begum, Ruwaida; Begum, Dipa; Lund, Tom; Sivamanoharan, Nanna; Sansano, Harold B.; Domingo-Arada, Melissa; Tran, Amina; Pandha, Hardev; Church, David; Eccles, Bryony; Ellis, Richard; Falk, Stephen; Hill, Mark; Krell, Daniel; Murugaesu, Nirupa; Nolan, Luke; Potter, Vanessa; Saunders, Mark; Shiu, Kai-Keen; Guettler, Sebastian; Alexander, James L.; Lazare-Iglesias, Hector; Kinross, James; Murphy, Jamie; von Loga, Katharina; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
PD1 and LAG3 inhibition as second plus line treatment after EGFR antibody-containing therapy in RAS/BRAF wildtype, MMRp metastatic colorectal cancer Mencel, J.; Turkes, F.; Barber, L.; Challoner, B.; Buzzetti, M.; Tran, A.; Chen, H.; McCafferty, N.; Woolston, A.; Crux, R.; Rana, I.; Thomas, J.; Borja, V.; Begum, R.; Johnston, E.; Fotiadis, N.; Terlizzo, M.; Rao, S.; Chau, I.; Cunningham, D.; Gerlinger, M.; Starling, N. Share Save
Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer Alexander, James L.; Posma, Joram M.; Scott, Alasdair; Poynter, Liam; Mason, Sam E.; Doria, M. Luisa; Herendi, Lili; Roberts, Lauren; McDonald, Julie A. K.; Cameron, Simon; Hughes, David J.; Liska, Vaclav; Susova, Simona; Soucek, Pavel; Der Sluis, Verena Horneffer-van; Gomez-Romero, Maria; Lewis, Matthew R.; Hoyles, Lesley; Woolston, Andrew; Cunningham, David; Darzi, Ara; Gerlinger, Marco; Goldin, Robert; Takats, Zoltan; Marchesi, Julian R.; Teare, Julian; Kinross, James Share Save
Clonal mutation burden and evolutionary dynamics analysis in metastatic gastro-esophageal adenocarcinoma (GEA) by error corrected whole-exome circulating tumor DNA sequencing McCafferty, Neil; Fong, Caroline; Barber, Louise J.; Woolston, Andrew; Kleftogiannis, Dimitrios; Rana, Taqia; Cromarty, Susan; Kidd, Shannon; Begum, Ruwaida; Chau, Ian; Starling, Naureen; Cunningham, David; Gerlinger, Marco Share Save
Circulating tumor DNA for recurrence prediction and efficacy analysis in the ICONIC trial of peri-operative FLOT and avelumab (PD-L1) in localized esophago-gastric adenocarcinoma Gerlinger, Marco; Gordon, Anderley; Barber, Louise J.; Laliotis, Georgios; Athauda, Avani; Challoner, Benjamin; Woolston, Andrew; Mansukhani, Sonia; Dunstan, Matt; Petrou, Nikoletta; Khabra, Komel; Lazaro-Alcausi, Retchel; Crux, Richard; Borja, Victoria; Begum, Ruwaida; Rana, Isma; Palsuledesai, Charuta; Malhotra, Meenakshi; Liu, Minetta; Jurdi, Adham; Sharma, Shruti; Rao, Sheela; Kumar, Sacheen; Cunningham, David; Chau, Ian; Starling, Naureen; Chaudry, M. Asif Share Save
Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Barber, Louise J.; Lund, Tom; Sansano, Harold B.; von Loga, Katharina; Lazare-Iglesias, Hector; Begum, Ruwaida; Crux, Richard; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Genetic and immune landscape evolution defines subtypes of MMR deficient colorectal cancer Challoner, Benjamin R.; Woolston, Andrew; Lau, David; Buzzetti, Marta; Barber, Louise J.; Lund, Tom; Sansano, Harold B.; von Loga, Katharina; Lazare-Iglesias, Hector; Begum, Ruwaida; Crux, Richard; Cunningham, David; Chau, Ian; Starling, Naureen; Ruiz-Banobre, Juan; Dhillon, Tony; Gerlinger, Marco Share Save
Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer Woolston, Andrew; Barber, Louise J.; Griffiths, Beatrice; Pich, Oriol; Lopez-Bigas, Nuria; Matthews, Nik; Rao, Sheela; Watkins, David; Chau, Ian; Starling, Naureen; Cunningham, David; Gerlinger, Marco Share Save
Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation Within Clinical Trial Data Khan, Khurum; Gonzalez-Exposito, Reyes; Cunningham, David; Koh, Dow-Mu; Woolston, Andrew; Barber, Louise; Griffiths, Beatrice; Kouvelakis, Kyriakos; Calamai, Vanessa; Bali, Monia; Khan, Nasir; Bryant, Annette; Saffery, Claire; Dearman, Charles; Begum, Ruwaida; Rao, Sheela; Starling, Naureen; Watkins, David; Chau, Ian; Braconi, Chiara; Valeri, Nicola; Gerlinger, Marco; Fotiadis, Nicos Share Save
Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes Challoner, Benjamin R.; von Loga, Katharina; Woolston, Andrew; Griffiths, Beatrice; Sivamanoharan, Nanna; Semiannikova, Maria; Newey, Alice; Barber, Louise J.; Mansfield, David; Hewitt, Lindsay C.; Saito, Yuichi; Davarzani, Naser; Starling, Naureen; Melcher, Alan; Grabsch, Heike, I; Gerlinger, Marco Share Save
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer (vol 11, 139, 2020) von Loga, Katharina; Woolston, Andrew; Punta, Marco; Barber, Louise J.; Griffiths, Beatrice; Semiannikova, Maria; Spain, Georgia; Challoner, Benjamin; Fenwick, Kerry; Simon, Ronald; Marx, Andreas; Sauter, Guido; Lise, Stefano; Matthews, Nik; Gerlinger, Marco Share Save
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer von Loga, Katharina; Woolston, Andrew; Punta, Marco; Barber, Louise J.; Griffiths, Beatrice; Semiannikova, Maria; Spain, Georgia; Challoner, Benjamin; Fenwick, Kerry; Simon, Ronald; Marx, Andreas; Sauter, Guido; Lise, Stefano; Matthews, Nik; Gerlinger, Marco Share Save
Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment Newey, Alice; Griffiths, Beatrice; Michaux, Justine; Pak, Hui Song; Stevenson, Brian J.; Woolston, Andrew; Semiannikova, Maria; Spain, Georgia; Barber, Louise J.; Matthews, Nik; Rao, Sheela; Watkins, David; Chau, Ian; Coukos, George; Racle, Julien; Gfeller, David; Starling, Naureen; Cunningham, David; Bassani-Sternberg, Michal; Gerlinger, Marco Share Save
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids Gonzalez-Exposito, Reyes; Semiannikova, Maria; Griffiths, Beatrice; Khan, Khurum; Barber, Louise J.; Woolston, Andrew; Spain, Georgia; von Loga, Katharina; Challoner, Ben; Patel, Radhika; Ranes, Michael; Swain, Amanda; Thomas, Janet; Bryant, Annette; Saffery, Claire; Fotiadis, Nicos; Guettler, Sebastian; Mansfield, David; Melcher, Alan; Powles, Thomas; Rao, Sheela; Watkins, David; Chau, Ian; Matthews, Nik; Wallberg, Fredrik; Starling, Naureen; Cunningham, David; Gerlinger, Marco Share Save
Ultra-Sensitive Mutation Detection and Genome-Wide DNA Copy Number Reconstruction by Error-Corrected Circulating Tumor DNA Sequencing Mansukhani, Sonia; Barber, Louise J.; Kleftogiannis, Dimitrios; Moorcraft, Sing Yu; Davidson, Michael; Woolston, Andrew; Proszek, Paula Zuzanna; Griffiths, Beatrice; Fenwick, Kerry; Herman, Bram; Matthews, Nik; O'Leary, Ben; Hulkki, Sanna; De Castro, David Gonzalez; Patel, Anisha; Wotherspoon, Andrew; Okachi, Aleruchi; Rana, Isma; Begum, Ruwaida; Davies, Matthew N.; Powles, Thomas; von Loga, Katharina; Hubank, Michael; Turner, Nick; Watkins, David; Chau, Ian; Cunningham, David; Lise, Stefano; Starling, Naureen; Gerlinger, Marco Share Save
Molecular subtypes and novel genetic mechanisms of primary and acquired anti-EGFR resistance in colorectal cancer in the Prospect C biomarker trial Khan, Khurum Hayat; Woolston, Andrew; Spain, Georgia; Barber, Louise; Patil, Yatish; Griffiths, Beatrice; GonzalezExposito, Reyes; Mansukhani, Sonia; Davies, Matthew; Rao, Sheela; Watkins, David; Sclafani, Francesco; Suntharanathan, Jana; Peckitt, Clare; Begum, Ruwaida; Rana, Isma; Thomas, Janet; Oates, Jacqui; Bryant, Annette; Wotherspoon, Andrew; Fotiadis, Nicos; Khan, Nasir; Guettler, Sebastian; von Loga, Katharina; Starling, Naureen; Chau, Ian; Sadanandam, Anguraj; Cunningham, David; Gerlinger, Marco Share Save
Lymph node metastasis evolution drives immune evasion and targeted therapy resistance in gastro-esophageal adenocarcinomas (GEAs) Davies, Matthew N.; Barber, Louise J.; Spain, Georgia; Lopes, Filipa; von Loga, Katharina; Griffiths, Beatrice; Woolston, Andrew; Alpar, Donat; Gomez, Marta; Lipinski, Kamil A.; Fenwick, Kerry; Eltahir, Zakaria; Lise, Stefano; Agoston, Emese I.; Harsanyi, Laszlo; Marais, Richard; Wotherspoon, Andrew; Szasz, A.; Springer, Caroline; Gerlinger, Marco Share Save
Prospective development and validation of a model to predict heart failure hospitalisation Cubbon, R. M.; Woolston, A.; Adams, B.; Gale, C. P.; Gilthorpe, M. S.; Baxter, P. D.; Kearney, L. C.; Mercer, B.; Rajwani, A.; Batin, P. D.; Kahn, M.; Sapsford, R. J.; Witte, K. K.; Kearney, M. T. Share Save
Resolving inequalities in care? Reduced mortality in the elderly after acute coronary syndromes. The Myocardial Ischaemia National Audit Project 2003-2010 Gale, Chris P.; Cattle, B. A.; Woolston, A.; Baxter, P. D.; West, T. H.; Simms, A. D.; Blaxill, J.; Greenwood, D. C.; Fox, K. A. A.; West, R. M. Share Save
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