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CD40 agonist mitazalimab combined with mFOLFIRINOX (mFFX) in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): Primary analysis of the OPTIMIZE-1 phase Ib/II study Macarulla Mercade, T.; Borbath, I.; Geboes, K.; Lambert, A.; Cassier, P.; Prenen, H.; Mitry, E.; Blanc, J. F.; Pilla, L.; Feliu, J.; Rodriguez, M.; Cid, R. A. Pazo; Gallego Jimenez, I.; Gomez Jimenez, D.; Smith, K. E.; Nordbladh, K.; Ellmark, P.; Pico de Coana, Y.; Ambarkhane, S. V.; van Laethem, J-L. Share Save
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CD40 agonist mitazalimab in combination with mFOLFIRINOX in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): Interim efficacy results of the OPTIMIZE-1 phase 1b/2 study Van Laethem, Jean-Luc; Geboes, Karen P.; Cassier, Philippe A.; Borbath, Ivan; Lambert, Aurelien; Mitry, Emmanuel; Prenen, Hans; Blanc, Jean-Frederic; Pilla, Lorenzo; Garrote, Mercedes Rodriguez; Cid, Roberto A. Pazo; Gallego, Inmaculada; Feliu, Jaime; Nordbladh, Karin; Ellmark, Peter; Carlsson, Malin; de Coana, Yago Pico; Ambarkhane, Sumeet V.; Macarulla, Teresa Share Save
Early Pharmacodynamic Changes Measured Using RNA Sequencing of Peripheral Blood from Patients in a Phase I Study with Mitazalimab, a Potent CD40 Agonistic Monoclonal Antibody Andersson, Hampus; Sobti, Aastha; Jimenez, David Gomez; de Coana, Yago Pico; Ambarkhane, Sumeet Vijay; Hagerbrand, Karin; Smith, Karin Enell; Lindstedt, Malin; Ellmark, Peter Share Save
ATOR-4066, a Neo-X-Prime bispecific antibody targeting CD40 and CEA, activates myeloid cells in primary human tumors in vitro and induces anti-tumor immunity in vivo Hagerbrand, Karin; Sundstedt, Anette; Levin, Mattias; de Coana, Yago Pico; Varas, Laura; Ljung, Lill; Nilsson, Anneli; Celander, Mona; Jimenez, David Gomez; Andersson, Hampus; Lindstedt, Malin; Ellmark, Peter Share Save
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PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates de Coana, Yago Pico; Wolodarski, Maria; Avila, Irene van der Haar; Nakajima, Takahiro; Rentouli, Stamatina; Lundqvist, Andreas; Masucci, Giuseppe; Hansson, Johan; Kiessling, Rolf Share Save
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Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma Ligtenberg, Maarten A.; de Coana, Yago Pico; Shmushkovich, Taisia; Yoshimoto, Yuya; Truxova, Iva; Yang, Yuan; Betancur-Boissel, Monica; Eliseev, Alexey V.; Wolfson, Alexey D.; Kiessling, Rolf Share Save
IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients Tallerico, Rossana a; Cristiani, Costanza M. a; Staaf, Elina b; Garofalo, Cinzia a; Sottile, Rosa ab; Capone, Mariaelena c; de Coana, Yago Pico d; Madonna, Gabriele c; Palella, Eleonora a; Wolodarski, Maria d; Carannante, Valentina b; Mallardo, Domenico c; Simeone, Ester c; Grimaldi, Antonio M. c; Johansson, Sofia b; Frumento, Paolo e; Gulletta, Elio f; Anichini, Andrea g; Colucci, Francesco h; Ciliberto, Gennaro i; Kiessling, Rolf d; Kaerre, Klas b; Ascierto, Paolo A. c; Carbone, Ennio ab Share Save
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Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2-Dependent Mechanisms Mao, Yumeng; Poschke, Isabel; Wennerberg, Erik; de Coana, Yago Pico; Brage, Suzanne Egyhazi; Schultz, Inkeri; Hansson, Johan; Masucci, Giuseppe; Lundqvist, Andreas; Kiessling, Rolf Share Save
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