Not logged in Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models Crouchet, Emilie; Schaeffer, Eugenie; Oudot, Marine A.; Moehlin, Julien; Gadenne, Cloe; Juhling, Frank; El Saghire, Hussein; Fujiwara, Naoto; Zhu, Shijia; Rasha, Fahmida Akter; Durand, Sarah C.; Charlot, Anouk; Ponsolles, Clara; Martin, Romain; Brignon, Nicolas; Del Zompo, Fabio; Meiss-Heydmann, Laura; Parnot, Marie; Hamdane, Nourdine; Heide, Danijela; Hetzer, Jenny; Heikenwalder, Mathias; Felli, Emanuele; Pessaux, Patrick; Pochet, Nathalie; Zoll, Joffrey; Cunniff, Brian; Hoshida, Yujin; Mailly, Laurent; Baumert, Thomas F.; Schuster, Catherine Share Save
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Mapping Redox Signaling Events in Early Metastatic Ovarian Cancer Tang, Priscilla; Elhaw, Amal; Cheng, Ya-Yun; Spencer, Connor; Benson, James; Wallace, Callen; St Croix, Claudette; Happe, Cassandra; Gelhaus, Stacy; Held, Jason; Trebak, Mohamed; Cunniff, Brian; Hempel, Nadine Share Save
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Leveraging Mitochondrial Metabolic and Energetic Differences to Target Prostate Cancer Regrowth Post Radiotherapy Guerrier, Kahleel; Clair, Daret St; Xu, Fang Fang; Izumi, Tadahide; Fan, Teresa; Islam, Jahid; Weiss, Heidi; Higashi, Richard; Clair, William St; Cunniff, Brian; Chaiswing, Luksana Share Save
Peroxiredoxin 3 (PRX3) - a new target for the treatment of aggressive cancers Gibson, V.; Dzialo, J.; Messier, T.; Baitei, E.; Poile, C.; Bzura, A.; Kutywayo, K.; Nakas, A.; Naumov, G.; Fennell, D.; Cunniff, B. Share Save
MITOPE: Phase 2 evaluation of RSO-021, a novel mitochondrial PRX3 inhibitor, as a monotherapy and in combination with paclitaxel in patients with malignant pleural effusion due to mesothelioma or other advanced solid tumors Naumov, G.; Dulloo, S.; Fennell, D.; Lord, S.; Thistlethwaite, F.; Maskell, N.; Popat, S.; Blyth, K.; Szlosarek, P.; Aujayeb, A.; Franks, K.; Herrero, J.; Cunniff, B.; Duncan, J.; Graham, P.; Bexon, A.; Spicer, J. Share Save
SLC7A11 modulates sensitivity to the first-in-class mitochondrial peroxiredoxin 3 inhibitor thiostrepton (RSO-021) via a ferroptosis independent pathway Messier, Terri; Gibson, Victoria; Bzura, Aleksandra; Dzialo, Joanna; Poile, Charlotte; Stead, Stephanie; Saaman, Alexis; Naumov, George N.; Fennell, Dean A.; Cunniff, Brian Share Save
First-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 triggers mesenchymal-to-epithelial transition in mesothelioma Messier, Terri; Gibson, Victoria; Seward, David J.; Baitei, Essa Y.; Jordan, Peter Wells; Poile, Charlotte; Dzialo, Joanna; Bzura, Aleksandra; Kutywayo, Kudzayi; Nakas, Apostolos; Naumov, George N.; Fennell, Dean A.; Cunniff, Brian Share Save
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RSO-021, a first-in-class covalent inhibitor of mitochondrial PRX3: From bench to bedside Fennell, Dean A.; Dulloo, Sean; Szlosarek, Peter; Thistlethwaite, Fiona; Lord, Simon; Rahman, Najib M.; Cunniff, Brian; Dzialo, Joanna; Poile, Charlotte; Panchal, Rakesh; Duncan, Jarrett; Graham, Pip; Bexon, Alice; Naumov, George N.; Spicer, James Share Save
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SIRT3/SOD2/H2O2-mediated redox signaling supports ovarian cancer anchorage-independence Tang, Priscilla; Elhaw, Amal; Benson, James; Wallace, Callen; St Croix, Claudette; Happe, Cassandra; Mullett, Steve; Gelhaus, Stacy; Trebak, Mohamed; Cunniff, Brian; Hempel, Nadine Share Save
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Deletion of Miro1 in airway club cells potentiates allergic asthma phenotypes Bruno, Sierra; Lamberty, Amelia; McCoy, Margaret; Mark, Zoe; Daphtary, Nirav; Aliyeva, Minara; Butnor, Kelly; Poynter, Matthew E.; Anathy, Vikas; Cunniff, Brian Share Save
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