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PREDICTING EARLY DEATH IN DIFFUSE MIDLINE GLIOMA Moloney, Sam; Carruthers, Vickyanne; Davis, Melissa J.; Bhuva, Dharmesh D.; Mignone, Cristina; Singh, Susan; Gardiner, Rebecca E.; Valvi, Santosh; Eisenstat, David D.; Hansford, Jordan R. Share Save
Spatial omics techniques and data analysis for cancer immunotherapy applications Zhang, Yue; Lee, Ren Yuan; Tan, Chin Wee; Guo, Xue; Yim, Willa W-Y; Lim, Jeffrey C. T.; Wee, Felicia Y. T.; Yang, Wu; Kharbanda, Malvika; Lee, Jia-Ying J.; Ngo, Nye Thane; Leow, Wei Qiang; Loo, Lit-Hsin; Lim, Tony K. H.; Sobota, Radoslaw M.; Lau, Mai Chan; Davis, Melissa J.; Yeong, Joe Share Save
Library size confounds biology in spatial transcriptomics data Bhuva, Dharmesh D.; Tan, Chin Wee; Salim, Agus; Marceaux, Claire; Pickering, Marie A.; Chen, Jinjin; Kharbanda, Malvika; Jin, Xinyi; Liu, Ning; Feher, Kristen; Putri, Givanna; Tilley, Wayne D.; Hickey, Theresa E.; Asselin-Labat, Marie-Liesse; Phipson, Belinda; Davis, Melissa J. Share Save
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ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia Behrens, Kira; Brajanovski, Natalie; Xu, Zhen; Viney, Elizabeth M.; Dirago, Ladina; Hediyeh-Zadeh, Soroor; Davis, Melissa J.; Pearson, Richard B.; Sanij, Elaine; Alexander, Warren S.; Ng, Ashley P. Share Save
In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection Tan, Chin Wee; Chen, Jinjin; Liu, Ning; Bhuva, Dharmesh D.; Blick, Tony; Monkman, James; Cooper, Caroline; Kharbanda, Malvika; Feher, Kristen; Phipson, Belinda; Killingbeck, Emily E.; Pan, Liuliu; Kim, Youngmi; Liang, Yan; Nam, Andy; Leon, Michael; Souza-Fonseca-Guimaraes, Paulo; Nagashima, Seigo; Martins, Ana Paula Camargo; Machado-Souza, Cleber; de Noronha, Lucia; Tang, Benjamin; Short, Kirsty; Fraser, John; Belz, Gabrielle T.; Souza-Fonseca-Guimaraes, Fernando; Kulasinghe, Arutha; Davis, Melissa J. Share Save
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development Goh, Wilford; Sudholz, Harrison; Foroutan, Momeneh; Scheer, Sebastian; Pfefferle, Aline; Delconte, Rebecca B.; Meng, Xiangpeng; Shen, Zihan; Hennessey, Robert; Kong, Isabella Y.; Schuster, Iona S.; Andoniou, Christopher E.; Davis, Melissa J.; Hediyeh-Zadeh, Soroor; Souza-Fonseca-Guimaraes, Fernando; Parish, Ian A.; Beavis, Paul; Thiele, Daniel; Chopin, Michael; Degli-Esposti, Mariapia A.; Cursons, Joe; Kallies, Axel; Rautela, Jai; Nutt, Stephen L.; Huntington, Nicholas D. Share Save
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Implementation of DNA Methylation Array Profiling in Pediatric Central Nervous System Tumors The AIM BRAIN Project: An Australian and New Zealand Children's Haematology/Oncology Group Study White, Christine L.; Kinross, Kathryn M.; Moore, Molly K.; Rasouli, Elnaz; Strong, Robyn; Jones, Janelle M.; Cain, Jason E.; Sturm, Dominik; Sahm, Felix; Jones, David T. W.; Pfister, Stefan M.; Robertson, Thomas; D'Arcy, Colleen; Rodriguez, Michael L.; Dyke, Jason M.; Junckerstorff, Reimar; Bhuva, Dharmesh D.; Davis, Melissa J.; Wood, Paul; Hassall, Tim; Ziegler, David S.; Kellie, Stewart; McCowage, Geoffrey; Alvaro, Frank; Kirby, Maria; Heath, John A.; Tsui, Karen; Dodgshun, Andrew; Eisenstat, David D.; Khuong-Quang, Dong-Anh; Wall, Meaghan; Algar, Elizabeth M.; Gottardo, Nicholas G.; Hansford, Jordan R. Share Save
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer Sharma, Shikhar; Chung, Chi-Yeh; Uryu, Sean; Petrovic, Jelena; Cao, Joan; Rickard, Amanda; Nady, Nataliya; Greasley, Samantha; Johnson, Eric; Brodsky, Oleg; Khan, Showkhin; Wang, Hui; Wang, Zhenxiong; Zhang, Yong; Tsaparikos, Konstantinos; Chen, Lei; Mazurek, Anthony; Lapek, John; Kung, Pei-Pei; Sutton, Scott; Richardson, Paul F.; Greenwald, Eric C.; Yamazaki, Shinji; Jones, Rhys; Maegley, Karen A.; Bingham, Patrick; Lam, Hieu; Stupple, Alexandra E.; Kamal, Aileen; Chueh, Anderly; Cuzzupe, Anthony; Morrow, Benjamin J.; Ren, Bin; Carrasco-Pozo, Catalina; Tan, Chin Wee; Bhuva, Dharmesh D.; Allan, Elizabeth; Surgenor, Elliot; Vaillant, Francois; Pehlivanoglu, Havva; Falk, Hendrik; Whittle, James R.; Newman, Janet; Cursons, Joseph; Doherty, Judy P.; White, Karen L.; Macpherson, Laura; Devlin, Mark; Dennis, Matthew L.; Hattarki, Meghan K.; De Silva, Melanie; Camerino, Michelle A.; Butler, Miriam S.; Dolezal, Olan; Pilling, Patricia; Foitzik, Richard; Stupple, Paul A.; Lagiakos, H. Rachel; Walker, Scott R.; Hediyeh-Zadeh, Soroor; Nuttall, Stewart; Spall, Sukhdeep; Charman, Susan A.; Connor, Theresa; Peat, Thomas S.; Avery, Vicky M.; Bozikis, Ylva E.; Yang, Yuqing; Zhang, Ming; Monahan, Brendon J.; Voss, Anne K.; Street, Ian P.; Dawson, Sarah-Jane; Dawson, Mark A.; Lindeman, Geoffrey J.; Davis, Melissa J.; Visvader, Jane E.; Paul, Thomas A. Share Save
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Single-cell RNA sequencing captures patient-level heterogeneity and associated molecular phenotypes in breast cancer pleural effusions Whitfield, Holly J.; Berthelet, Jean; Mangiola, Stefano; Bell, Caroline; Anderson, Robin L.; Pal, Bhupinder; Yeo, Belinda; Papenfuss, Anthony T.; Merino, Delphine; Davis, Melissa J. Share Save
Basonuclin-2 regulates extracellular matrix production and degradation Orang, Ayla; Dredge, B. Kate; Liu, Chi Yau; Bracken, Julie M.; Chen, Chun-Hsien; Sourdin, Laura; Whitfield, Holly J.; Lumb, Rachael; Boyle, Sarah; Davis, Melissa J.; Samuel, Michael S.; Gregory, Philip A.; Khew-Goodall, Yeesim; Goodall, Gregory J.; Pillman, Katherine A.; Bracken, Cameron P. Share Save
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Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer Waryah, Charlene; Cursons, Joseph; Foroutan, Momeneh; Pflueger, Christian; Wang, Edina; Molania, Ramyar; Sorolla, Anabel; Wallis, Christopher; Moses, Colette; Glas, Irina; Magalhaes, Leandro; Thompson, Erik W.; Fearnley, Liam G.; Chaffer, Christine L.; Davis, Melissa; Papenfuss, Anthony T.; Redfern, Andrew; Lister, Ryan; Esteller, Manel; Blancafort, Pilar Share Save
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Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition Vo, Tuan; Balderson, Brad; Jones, Kahli; Ni, Guiyan; Crawford, Joanna; Millar, Amanda; Tolson, Elissa; Singleton, Matthew; Kojic, Marija; Robertson, Thomas; Walters, Shaun; Mulay, Onkar; Bhuva, Dharmesh D.; Davis, Melissa J.; Wainwright, Brandon J.; Nguyen, Quan; Genovesi, Laura A. Share Save
Spatial profiling of the tumor microenvironment in head and neck cancer identifies immune checkpoints and proteins involved in cell death signaling biomarkers of immunotherapy response Sadeghirad, Habib; Liu, Ning; Monkman, James; Tan, Chin Wee; Cooper, Caroline; Caldera, Jeni; Church, Sarah; Schneider, Fabian; Mansfield, James Robert; O'Byrne, Ken; Davis, Melissa; Hughes, Brett; Kulasinghe, Arutha Share Save