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Digital Spatial Immune Profiling of Colorectal Liver Macro-metastases and Micro-metastases Jadhav, Akshaya; Hernandez, Sharia; Lermi, Nejla Ozirmak; Khanduri, Isha; Mejia, Alicia; Tong, Zhimin; Lu, Wei; Khan, Khaja; Kostousov, Larisa; Barnes, Sean; Wistuba, Ignacio; Chen, Ken; Menter, David; Kopetz, Scott; Soto, Luisa Solis; Maru, Dipen Share Save
The PLK1 inhibitor, onvansertib, is active as monotherapy and in combination with cetuximab in RAS wild-type colorectal cancer patient-derived xenografts Ridinger, Maya; Marie, Preeti Kanikarla; Gao, Fengqin; Liu, Zhensheng; Maddalena, Giulia; Menter, David; Sorokin, Alexey; Smeal, Tod; Kopetz, Scott Share Save
Cell-type-specific gene programs suggest immune and stromal drivers of relapse in colorectal cancer Hornstein, Nicholas J.; Wang, Mingshuang; Yousef, Abdelrahman; Chowdhury, Saikat; Zeineddine, Fadl; Zeineddine, Mohammad; Yousef, Mahmoud; You, Shuangjie; Gunes, Betul; Menter, David; Kopetz, Scott; Shen, John Paul Share Save
Anti-CSF1R antibody monotherapy inhibits minimal residual disease in a novel immunocompetent murine colorectal cancer metastasis model Mohamed, Alaa M.; Cho, Kyung Serk; Soeung, Melinda; Anderson, Amanda; Alshenaifi, Jumanah; Manyam, Ganiraju; Villareal, Oscar; Davis, Jennifer; Norton, Will; Gao, Sisi; Bristow, Christopher; Carbone, Federica; Napolitano, Stefania; Coker, Oluwadara; Khanduri, Isha; Huang, Justin; Maru, Dipen M.; Di Pilato, Mauro; Sun, Ryan; Wang, Linghua; Menter, David G.; Genovese, Giannicola; Draetta, Giulio; Fowlkes, Natalie; Kopetz, Scott Share Save
YAP-TAZ-TEAD transcriptional program is a prominent driver of acquired resistance to KRASG12C-based therapies in patients with metastatic colorectal cancer Coker, Oluwadara; Sorokin, Alexey; Akhave, Neal; Pan, Kelsey; Gao, Fengqin; Liu, Zhensheng; Kanikarla, Preeti; Lee, HeyMin; Villarreal, Oscar; Alshenaifi, Jumanah; Maddalena, Giulia; Mohamed, Alaa; Prescod, Dionne; Menter, David; Chowdury, Saikat; Corcoran, Ryan; Rai, Kunal; Hong, David; Kopetz, Scott Share Save
Identification of Colorectal Cancer Cell Stemness from Single-Cell RNA Sequencing Lin, Kangyu; Chowdhury, Saikat; Zeineddine, Mohammad A.; Zeineddine, Fadl A.; Hornstein, Nicholas J.; Villarreal, Oscar E.; Maru, Dipen M.; Haymaker, Cara L.; Vauthey, Jean-Nicolas; Chang, George J.; Bogatenkova, Elena; Menter, David; Kopetz, Scott; Shen, John Paul Share Save
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Recapitulating metastatic colorectal cancer in somatic mutation models for investigating the tumor immune microenvironment in minimal residual disease Mohamed, Alaa M.; Soeung, Melinda; Alshenaifi, Jumanah; Fowlkes, Natalie; Manyam, Ganiraju; Davis, Jennifer; Anderson, Amanda; Norton, Will; Deem, Angela K.; Gao, Sisi; Khanduri, Isha; Bistow, Christopher; Carbone, Federica; Napolitano, Stefania; Huang, Justin; Maru, Dipen M.; Menter, David G.; Draetta, Giulio F.; Genovese, Giannicola; Kopetz, Scott Share Save
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Phase 1 study of the safety, pharmacokinetics, and preliminary efficacy of CA102N as monotherapy and in combination with trifluridine-tipiracil in patients with locally advanced or metastatic solid tumors Pant, Shubham; Dragovich, Tomislav; Lieu, Christopher; Jimeno, Antonio; Kundranda, Madappa; Menter, David; Tchaparian, Eskouhie; Chen, Yuchih C.; Kopetz, Scott Share Save
Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts Kanikarla Marie, Preeti; Sorokin, Alexey V.; Bitner, Lea A.; Aden, Rebecca; Lam, Michael; Manyam, Ganiraju; Woods, Melanie N.; Anderson, Amanda; Capasso, Anna; Fowlkes, Natalie; Overman, Michael J.; Menter, David G.; Kopetz, Scott Share Save
Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6 Sorokin, Alexey V.; Marie, Preeti Kanikarla; Bitner, Lea; Syed, Muddassir; Woods, Melanie; Manyam, Ganiraju; Kwong, Lawrence N.; Johnson, Benny; Morris, Van K.; Jones, Philip; Menter, David G.; Lee, Michael S.; Kopetz, Scott Share Save
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Precision Combination Therapies Based on Recurrent Oncogenic Coalterations Li, Xubin; Dowling, Elisabeth K.; Yan, Gonghong; Dereli, Zeynep; Bozorgui, Behnaz; Imanirad, Parisa; Elnaggar, Jacob H.; Luna, Augustin; Menter, David G.; Pilie, Patrick G.; Yap, Timothy A.; Kopetz, Scott; Sander, Chris; Korkut, Anil Share Save
Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective Menter, David G.; Afshar-Kharghan, Vahid; Shen, John Paul; Martch, Stephanie L.; Maitra, Anirban; Kopetz, Scott; Honn, Kenneth, V; Sood, Anil K. Share Save
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The Provocative Roles of Platelets in Liver Disease and Cancer Kanikarla Marie, Preeti; Fowlkes, Natalie W.; Afshar-Kharghan, Vahid; Martch, Stephanie L.; Sorokin, Alexey; Shen, John Paul; Morris, Van K.; Dasari, Arvind; You, Nancy; Sood, Anil K.; Overman, Michael J.; Kopetz, Scott; Menter, David George Share Save
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