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RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells Chen, Fuhui; Gurler, Sevim B.; Novo, David; Selli, Cigdem; Alferez, Denis G.; Eroglu, Secil; Pavlou, Kyriaki; Zhang, Jingwei; Sims, Andrew H.; Humphreys, Neil E.; Adamson, Antony; Campbell, Andrew; Sansom, Owen J.; Tournier, Cathy; Clarke, Robert B.; Brennan, Keith; Streuli, Charles H.; Ucar, Ahmet Share Save
Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer Millar, Fraser R.; Pennycuick, Adam; Muir, Morwenna; Quintanilla, Andrea; Hari, Priya; Freyer, Elisabeth; Gautier, Philippe; Meynert, Alison; Grimes, Graeme; Coll, Carla Salomo; Zdral, Sofia; Victorelli, Stella; Teixeira, Vitor H.; Connelly, John; Passos, Joao F.; Ros, Marian A.; Wallace, William A. H.; Frame, Margaret C.; Sims, Andrew H.; Boulter, Luke; Janes, Sam M.; Wilkinson, Simon; Acosta, Juan Carlos Share Save
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MYC sensitises cells to apoptosis by driving energetic demand Edwards-Hicks, Joy; Su, Huizhong; Mangolini, Maurizio; Yoneten, Kubra K.; Wills, Jimi; Rodriguez-Blanco, Giovanny; Young, Christine; Cho, Kevin; Barker, Heather; Muir, Morwenna; Guerrieri, Ania Naila; Li, Xue-Feng; White, Rachel; Manasterski, Piotr; Mandrou, Elena; Wills, Karen; Chen, Jingyu; Abraham, Emily; Sateri, Kianoosh; Qian, Bin-Zhi; Bankhead, Peter; Arends, Mark; Gammoh, Noor; von Kriegsheim, Alex; Patti, Gary J.; Sims, Andrew H.; Acosta, Juan Carlos; Brunton, Valerie; Kranc, Kamil R.; Christophorou, Maria; Pearce, Erika L.; Ringshausen, Ingo; Finch, Andrew J. Share Save
Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors Beetham, Henry; Griffith, Billie G. C.; Murina, Olga; Loftus, Alexander E. P.; Parry, David A.; Temps, Carolin; Culley, Jayne; Muir, Morwenna; Unciti-Broceta, Asier; Sims, Andrew H.; Byron, Adam; Brunton, Valerie G. Share Save
Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia Williams, Rebecca; Jobling, Stephanie; Sims, Andrew H.; Mou, Chunyan; Wilkinson, Lorna; Collu, Giovanna M.; Streuli, Charles H.; Gilmore, Andrew P.; Headon, Denis J.; Brennan, Keith Share Save
Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells Vella, Veronica; Giuliano, Marika; La Ferlita, Alessandro; Pellegrino, Michele; Gaudenzi, Germano; Alaimo, Salvatore; Massimino, Michele; Pulvirenti, Alfredo; Dicitore, Alessandra; Vigneri, Paolo; Vitale, Giovanni; Malaguarnera, Roberta; Morrione, Andrea; Sims, Andrew H.; Ferro, Alfredo; Maggiolini, Marcello; Lappano, Rosamaria; De Francesco, Ernestina Marianna; Belfiore, Antonino Share Save
Steroid Ligands, the Forgotten Triggers of Nuclear Receptor Action; Implications for Acquired Resistance to Endocrine Therapy Bleach, Rachel; Madden, Stephen F.; Hawley, James; Charmsaz, Sara; Selli, Cigdem; Sheehan, Katherine M.; Young, Leonie S.; Sims, Andrew H.; Soucek, Pavel; Hill, Arnold D.; McIlroy, Marie Share Save
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function Campbell, Kirsteen J.; Mason, Susan M.; Winder, Matthew L.; Willemsen, Rosalie B. E.; Cloix, Catherine; Lawson, Hannah; Rooney, Nicholas; Dhayade, Sandeep; Sims, Andrew H.; Blyth, Karen; Tait, Stephen W. G. Share Save
Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype Vareslija, Damir; Ward, Elspeth; Purcell, Siobhan P.; Cosgrove, Nicola S.; Cocchiglia, Sinead; O'Halloran, Philip J.; Charmsaz, Sara; Bane, Fiona T.; Brett, Francesca M.; Farrell, Michael; Cryan, Jane; Beausang, Alan; Hudson, Lance; Turnbul, Arran K.; Dixon, J. Michael; Hill, Arnold D. K.; Priedigkeit, Nolan; Oesterreich, Steffi; Lee, Adrian V.; Sims, Andrew H.; Redmond, Aisling M.; Carroll, Jason S.; Young, Leonie S. Share Save
Combined administration of a small-molecule inhibitor of TRAF6 and Docetaxel reduces breast cancer skeletal metastasis and osteolysis Bishop, Ryan T.; Marino, Silvia; Carrasco, Giovana; Li, Boya; Allen, Richard J.; Sparatore, Anna; Ottewell, Penelope D.; Mollat, Patrick; Sims, Andrew H.; Capulli, Mattia; Wang, Ning; Idris, Aymen I. Share Save
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Monocyte-derived macrophages promote breast cancer bone metastasis outgrowth Ma, Ruo-Yu; Zhang, Hui; Li, Xue-Feng; Zhang, Cheng-Bin; Selli, Cigdem; Tagliavini, Giulia; Lam, Alyson D.; Prost, Sandrine; Sims, Andrew H.; Hu, Hai-Yan; Ying, Tianlei; Wang, Zhan; Ye, Zhaoming; Pollard, Jeffrey W.; Qian, Bin-Zhi Share Save
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs) Lappano, Rosamaria; Talia, Marianna; Cirillo, Francesca; Rigiracciolo, Damiano Cosimo; Scordamaglia, Domenica; Guzzi, Rita; Miglietta, Anna Maria; De Francesco, Ernestina Marianna; Belfiore, Antonino; Sims, Andrew H.; Maggiolini, Marcello Share Save
Increased Expression of Interleukin-1 Receptor Characterizes Anti-estrogen-Resistant ALDH+ Breast Cancer Stem Cells Sarmiento-Castro, Aida; Caamano-Gutierrez, Eva; Sims, Andrew H.; Hull, Nathan J.; James, Mark I.; Santiago-Gomez, Angelica; Eyre, Rachel; Clark, Christopher; Brown, Martha E.; Brooks, Michael D.; Wicha, Max S.; Howell, Sacha J.; Clarke, Robert B.; Simoes, Bruno M. Share Save
PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation Johansson, Jeanette A.; Marie, Kerrie L.; Lu, Yuting; Brombin, Alessandro; Santoriello, Cristina; Zeng, Zhiqiang; Zich, Judith; Gautier, Philippe; von Kriegsheim, Alex; Brunsdon, Hannah; Wheeler, Ann P.; Dreger, Marcel; Houston, Douglas R.; Dooley, Christopher M.; Sims, Andrew H.; Busch-Nentwich, Elisabeth M.; Zon, Leonard, I; Illingworth, Robert S.; Patton, E. Elizabeth Share Save
Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer Simoes, Bruno M.; Santiago-Gomez, Angelica; Chiodo, Chiara; Moreira, Tiago; Conole, Daniel; Lovell, Scott; Alferez, Denis; Eyre, Rachel; Spence, Katherine; Sarmiento-Castro, Aida; Kohler, Bertram; Morisset, Ludivine; Lanzino, Marilena; Ando, Sebastiano; Marangoni, Elisabetta; Sims, Andrew H.; Tate, Edward W.; Howell, Sacha J.; Clarke, Robert B. Share Save
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