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SaveShare Save Ferroptosis as a therapeutic vulnerability in MDM2 inhibition in dedifferentiated liposarcoma
Yen, Chueh-Chuan; Chen, Paul Chih-Hsueh; Chen, San-Chi; Wu, Wen-Chi; Yen, Chiao-Han; Lin, Yung-Chan; Wu, Po-Kuei; Chen, Chao-Ming; Wang, Jir-You; Chao, Ta-Chung; Yang, Muh-Hwa; Fletcher, Jonathan A. Share Save Clinical application of capsule sponge testing in symptomatic reflux disease: a national prospective cohort studyChien, Siobhan; Glen, Paul; Bryce, Gavin; Cruickshank, Neil; Penman, Ian; Robertson, Kevin; Phull, Perminder; Crumley, Andrew; Gunjaca, Ivan; Apollos, Jeyakumar; Miller, Michael; Fletcher, Jonathan; Fullarton, Grant Share Save Oesophageal cell collection device and biomarker testing to identify high-risk Barrett's patients requiring endoscopic investigationChien, Siobhan; Glen, Paul; Penman, Ian; Cruickshank, Neil; Bryce, Gavin; Crumley, Andrew; Phull, Perminder; Miller, Michael; Fletcher, Jonathan; Gunjaca, Ivan; Apollos, Jeyakumar; Robertson, Kevin; Fullarton, Grant Share Save Leiomyosarcoma poly-aneuploid cancer cells form in response to chemotherapy, contribute to chemoresistance, and lead to higher rates of metastatic recurrenceKennington, Ryan; Mitchell, Gareth; Payne, Emily; Bhachech, Niraja; Fletcher, Jonathan A.; Liu, Ting; van de Rijn, Matt; Amend, Sarah; Pienta, Kenneth J.; Schiffman, Joshua D.; Abegglen, Lisa M. Share Save Share Save Share Save Leiomyosarcoma poly-aneuploid cancer cells form in response to chemotherapy and contribute to chemoresistanceAbegglen, Lisa M.; Bhachech, Niraja; Mitchell, Gareth; Kennington, Ryan; Nelson, Brad; Sharp, Miranda; Buccilli, Matthew; Iovino, Anthony; Rohaj, Aarushi; Fletcher, Jonathan A.; Liu, Ting; van de Rijn, Matt; Amend, Sarah R.; Pienta, Kenneth J.; Schiffman, Joshua D. Share Save Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GISTSchaefer, Inga-Marie; Hemming, Matthew L.; Lundberg, Meijun Z.; Serrata, Matthew P.; Goldaracena, Isabel; Liu, Ninning; Yin, Peng; Paulo, Joao A.; Gygi, Steven P.; George, Suzanne; Morgan, Jeffrey A.; Bertagnolli, Monica M.; Sicinska, Ewa T.; Chu, Chen; Zheng, Shanshan; Marino-Enriquez, Adrian; Hornick, Jason L.; Raut, Chandrajit P.; Ou, Wen-Bin; Demetri, George D.; Saka, Sinem K.; Fletcher, Jonathan A. Share Save Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcomaFiorito, Elisa; Szybowska, Patrycja; Haugsten, Ellen M.; Kostas, Michal; Oy, Geir F.; Wiedlocha, Antoni; Singh, Sachin; Nakken, Sigve; Maelandsmo, Gunhild M.; Fletcher, Jonathan A.; Meza-Zepeda, Leonardo A.; Wesche, Jorgen Share Save PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral MimicryPatel, Amish J.; Warda, Sarah; Maag, Jesper L., V; Misra, Rohan; Miranda-Roman, Miguel A.; Pachai, Mohini R.; Lee, Cindy J.; Li, Dan; Wang, Naitao; Bayshtok, Gabriella; Fishinevich, Eve; Meng, Yinuo; Wong, Elissa W. P.; Yan, Juan; Giff, Emily; Pappalardi, Melissa B.; McCabe, Michael T.; Fletcher, Jonathan A.; Rudin, Charles M.; Chandarlapaty, Sarat; Scandura, Joseph M.; Koche, Richard P.; Glass, Jacob L.; Antonescu, Cristina R.; Zheng, Deyou; Chen, Yu; Chi, Ping Share Save E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumorGarcia-Valverde, Alfonso; Rosell, Jordi; Sayols, Sergi; Gomez-Peregrina, David; Pilco-Janeta, Daniel F.; Olivares-Rivas, Ivan; de Alava, Enrique; Maurel, Joan; Rubio-Casadevall, Jordi; Esteve, Anna; Gut, Marta; Valverde, Claudia; Barretina, Jordi; Carles, Joan; Demetri, George D.; Fletcher, Jonathan A.; Arribas, Joaquin; Serrano, Cesar Share Save E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancerLi, Ke; Zheng, Xufen; Tang, Hua; Zang, Yuan-Sheng; Zeng, Chunling; Liu, Xiaoxiao; Shen, Yanying; Pang, Yuzhi; Wang, Simin; Xie, Feifei; Lu, Xiaojing; Luo, Yuxiang; Li, Zhang; Bi, Wenbo; Jia, Xiaona; Huang, Tao; Wei, Rongqiang; Huang, Kenan; Chen, Zihao; Zhu, Qingchen; He, Yi; Zhang, Miaoying; Gu, Zhizhan; Xiao, Yichuan; Zhang, Xiaoyang; Fletcher, Jonathan A.; Wang, Yuexiang Share Save Share Save Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase DomainGrunewald, Susanne; Klug, Lillian R.; Muhlenberg, Thomas; Lategahn, Jonas; Falkenhorst, Johanna; Town, Ajia; Ehrt, Christiane; Wardelmann, Eva; Hartmann, Wolfgang; Schildhaus, Hans-Ulrich; Treckmann, Juergen; Fletcher, Jonathan A.; Jung, Sascha; Czodrowski, Paul; Miller, Stephen; Schmidt-Kittler, Oleg; Rauh, Daniel; Heinrich, Michael C.; Bauer, Sebastian Share Save FBXO32 ubiquitin ligase mediates apoptosis evasion and adaptation to KIT inhibition in gastrointestinal stromal tumor - GISTGarcia Valverde, Alfonso; Rosell, Jordi; Pilco Janeta, Daniel; Sayols, Sergi; Valverde, Claudia; Esteve, Anna; Gut, Marta; Barretina, Jordi; Demetri, George D.; Fletcher, Jonathan A.; Carles, Joan; Arribas, Joaquin; Serrano, Cesar Share Save Preclinical Activity of PI3K Inhibitor Copanlisib in Gastrointestinal Stromal TumorGarcia-Valverde, Alfonso; Rosell, Jordi; Serna, Garazi; Valverde, Claudia; Carles, Joan; Nuciforo, Paolo; Fletcher, Jonathan A.; Arribas, Joaquin; Politz, Oliver; Serrano, Cesar Share Save Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumorsSerrano, Cesar; Vivancos, Ana; Lopez-Pousa, Antonio; Matito, Judit; Mancuso, Francesco M.; Valverde, Claudia; Quiroga, Sergi; Landolfi, Stefania; Castro, Sandra; Dopazo, Cristina; Sebio, Ana; Virgili, Anna C.; Menso, Maria M.; Martin-Broto, Javier; Sanso, Miriam; Garcia-Valverde, Alfonso; Rosell, Jordi; Fletcher, Jonathan A.; George, Suzanne; Carles, Joan; Arribas, Joaquin Share Save Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumoursHuang, Mengyuan; Yang, Wenyu; Zhu, Jiaqing; Marino-Enriquez, Adrian; Zhu, Chennianci; Chen, Jiaming; Wu, Yuehong; Quan, Yanping; Qiu, Haibo; Li, Xuhui; Chai, Li; Fletcher, Jonathan A.; Ou, Wen-Bin Share Save 
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