Not logged inCBL0137 and NKG2A blockade: a novel immuno-oncology combination therapy for Myc-overexpressing triple-negative breast cancers
Raninga, Prahlad V.; Zeng, Bijun; Moi, Davide; Trethowan, Ethan; Saletta, Federica; Venkat, Pooja; Mayoh, Chelsea; D'Souza, Rochelle C. J.; Day, Bryan W.; Shai-Hee, Tyler; Vittorio, Orazio; Mazzieri, Roberta; Dolcetti, Riccardo; Khanna, Kum Kum .png)
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SaveShare Save Share Save COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasisHancock, Janelle L.; Kalimutho, Murugan; Straube, Jasmin; Lim, Malcolm; Gresshoff, Irma; Saunus, Jodi M.; Lee, Jason S.; Lakhani, Sunil R.; Simpson, Kaylene J.; Bush, Ashley I.; Anderson, Robin L.; Khanna, Kum Kum Share Save Share Save Involvement of human MOF in ATM functionGupta, A; Sharma, GG; Young, CSH; Agarwal, M; Smith, ER; Paull, TT; Lucchesi, JC; Khanna, KK; Ludwig, T; Pandita, TK Share Save Chromatinized Protein Kinase C-θ Directly Regulates Inducible Genes in Epithelial to Mesenchymal Transition and Breast Cancer Stem CellsZafar, Anjum; Wu, Fan; Hardy, Kristine; Li, Jasmine; Tu, Wen Juan; McCuaig, Robert; Harris, Janelle; Khanna, Kum Kum; Attema, Joanne; Gregory, Philip A.; Goodall, Gregory J.; Harrington, Kirsti; Dahlstrom, Jane E.; Boulding, Tara; Madden, Rebecca; Tan, Abel; Milburn, Peter J.; Rao, Sudha Share Save Lamin A/C Depletion Enhances DNA Damage-Induced Stalled Replication Fork ArrestSingh, Mayank; Hunt, Clayton R.; Pandita, Raj K.; Kumar, Rakesh; Yang, Chin-Rang; Horikoshi, Nobuo; Bachoo, Robert; Serag, Sara; Story, Michael D.; Shay, Jerry W.; Powell, Simon N.; Gupta, Arun; Jeffery, Jessie; Pandita, Shruti; Chen, Benjamin P. C.; Deckbar, Dorothee; Loebrich, Markus; Yang, Qin; Khanna, Kum Kum; Worman, Howard J.; Pandita, Tej K. Share Save Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinomaRaninga, Prahlad V.; He, Yaowu; Datta, Keshava K.; Lu, Xue; Maheshwari, Uma R.; Venkat, Pooja; Mayoh, Chelsea; Gowda, Harsha; Kalimutho, Murugan; Hooper, John D.; Khanna, Kum Kum Share Save Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in miceRashidieh, Behnam; Bain, Amanda Louise; Tria, Simon Manuel; Sharma, Sowmya; Stewart, Cameron Allan; Simmons, Jacinta Ley; Apaja, Pirjo M.; Duijf, Pascal H. G.; Finnie, John; Khanna, Kum Kum Share Save CBL0137 impairs homologous recombination repair and sensitizes high-grade serous ovarian carcinoma to PARP inhibitorsLu, Xue; He, Yaowu; Johnston, Rebecca L.; Nanayakarra, Devathri; Sankarasubramanian, Sivanandhini; Lopez, J. Alejandro; Friedlander, Michael; Kalimutho, Murugan; Hooper, John D.; Raninga, Prahlad V.; Khanna, Kum Kum Share Save Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancerSaunus, Jodi M.; De Luca, Xavier M.; Northwood, Korinne; Raghavendra, Ashwini; Hasson, Alexander; Reed, Amy E. McCart; Lim, Malcolm; Lal, Samir; Vargas, A. Cristina; Kutasovic, Jamie R.; Dalley, Andrew J.; Miranda, Mariska; Kalaw, Emarene; Kalita-de Croft, Priyakshi; Gresshoff, Irma; Al-Ejeh, Fares; Gee, Julia M. W.; Ormandy, Chris; Khanna, Kum Kum; Beesley, Jonathan; Chenevix-Trench, Georgia; Green, Andrew R.; Rakha, Emad A.; Ellis, Ian O.; Nicolau, Dan V., Jr.; Simpson, Peter T.; Lakhani, Sunil R. Share Save Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesisRashidieh, Behnam; Shohayeb, Belal; Bain, Amanda Louise; Fortuna, Patrick R. J.; Sinha, Debottam; Burgess, Andrew; Mills, Richard; Adams, Rachael C.; Lopez, J. Alejandro; Blumbergs, Peter; Finnie, John; Kalimutho, Murugan; Piper, Michael; Hudson, James Edward; Ng, Dominic C. H.; Khanna, Kum Kum Share Save hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damageBoucher, Didier; Kariawasam, Ruvini; Burgess, Joshua; Gimenez, Adrian; Ocampo, Tristan E.; Ferguson, Blake; Naqi, Ali; Walker, Graeme J.; Bolderson, Emma; Gamsjaeger, Roland; O'Byrne, Kenneth J.; Cubeddu, Liza; Khanna, Kum Kum; Richard, Derek J. Share Save Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress responseMcmahon, Kerrie-Ann; Stroud, David A.; Gambin, Yann; Tillu, Vikas; Bastiani, Michele; Sierecki, Emma; Polinkovsky, Mark E.; Hall, Thomas E.; Gomez, Guillermo A.; Wu, Yeping; Parat, Marie-Odile; Martel, Nick; Lo, Harriet P.; Khanna, Kum Kum; Alexandrov, Kirill; Daly, Roger; Yap, Alpha; Ryan, Michael T.; Parton, Robert G. Share Save WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesisHo, Uda Y.; Feng, Chun-Wei Allen; Yeap, Yvonne Y.; Bain, Amanda L.; Wei, Zhe; Shohayeb, Belal; Reichelt, Melissa E.; Homer, Hayden; Khanna, Kum Kum; Bowles, Josephine; Ng, Dominic C. H. Share Save Cep55 overexpression promotes genomic instability and tumorigenesis in miceSinha, Debottam; Nag, Purba; Nanayakkara, Devathri; Duijf, Pascal H. G.; Burgess, Andrew; Raninga, Prahlad; Smits, Veronique A. J.; Bain, Amanda L.; Subramanian, Goutham; Wall, Meaghan; Finnie, John W.; Kalimutho, Murugan; Khanna, Kum Kum Share Save CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancerSanij, Elaine; Hannan, Katherine M.; Xuan, Jiachen; Yan, Shunfei; Ahern, Jessica E.; Trigos, Anna S.; Brajanovski, Natalie; Son, Jinbae; Chan, Keefe T.; Kondrashova, Olga; Lieschke, Elizabeth; Wakefield, Matthew J.; Frank, Daniel; Ellis, Sarah; Cullinane, Carleen; Kang, Jian; Poortinga, Gretchen; Nag, Purba; Deans, Andrew J.; Khanna, Kum Kum; Mileshkin, Linda; McArthur, Grant A.; Soong, John; Berns, Els M. J. J.; Hannan, Ross D.; Scott, Clare L.; Sheppard, Karen E.; Pearson, Richard B. Share Save Share Save Chromosome arm aneuploidies shape tumour evolution and drug responseShukla, Ankit; Nguyen, Thu H. M.; Moka, Sarat B.; Ellis, Jonathan J.; Grady, John P.; Oey, Harald; Cristino, Alexandre S.; Khanna, Kum Kum; Kroese, Dirk P.; Krause, Lutz; Dray, Eloise; Fink, J. Lynn; Duijf, Pascal H. G. Share Save 
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