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Developmental deletion of amyloid precursor protein precludes transcriptional and proteomic responses to brain injury Lacovich, V; Carna, M; Novotny, SJ; Wang, SS; Texlová, K; Kovacovicova, KL; Dragisic, N; Havas, D; Head, BP; Geda, YE; Limbäck-Stokin, C; Stokin, GB Share Save
Amyloid precursor protein induces reactive astrogliosis Jauregui, Gretsen Velezmoro; Vukic, Dragana; Onyango, Isaac G.; Arias, Carlos; Novotny, Jan S.; Texlova, Katerina; Wang, Shanshan; Kovacovicova, Kristina Locker; Polakova, Natalie; Zelinkova, Jana; Carna, Maria; Lacovich, Valentina; Head, Brian P.; Havas, Daniel; Mistrik, Martin; Zorec, Robert; Verkhratsky, Alexei; Keegan, Liam; O'Connell, Mary A.; Rissman, Robert; Stokin, Gorazd B. Share Save
Swedish Alzheimer's disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways Feole, Monica; Devoto, Victorio M. Pozo; Dragisic, Neda; Arnaiz, Cayetana; Bianchelli, Julieta; Texlova, Katerina; Kovacovicova, Kristina; Novotny, Jan S.; Havas, Daniel; Falzone, Tomas L.; Stokin, Gorazd B. Share Save
Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau Foster, Kelly; Manca, Matteo; McClure, Kim; Koivula, Pyry; Trojanowski, John Q.; Havas, Daniel; Chancellor, Sarah; Goldstein, Lee; Brunden, Kurt R.; Kraus, Allison; Ahlijanian, Michael K. Share Save
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD Afroz, Tariq; Chevalier, Elodie; Audrain, Mickael; Dumayne, Christopher; Ziehm, Tamar; Moser, Roger; Egesipe, Anne-Laure; Mottier, Lorene; Ratnam, Monisha; Neumann, Manuela; Havas, Daniel; Ollier, Romain; Piorkowska, Kasia; Chauhan, Mayank; Silva, Alberto B.; Thapa, Samjhana; Stohr, Jan; Bavdek, Andrej; Eligert, Valerie; Adolfsson, Oskar; Nelson, Peter T.; Porta, Silvia; Lee, Virginia M. -Y.; Pfeifer, Andrea; Kosco-Vilbois, Marie; Seredenina, Tamara Share Save
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form Collier, Timothy J.; Srivastava, Kinshuk R.; Justman, Craig; Grammatopoulous, Tom; Hutter-Paier, Birgit; Prokesch, Manuela; Havas, Daniel; Rochet, Jean-Christophe; Liu, Fang; Jock, Kevin; de Oliveira, Patricia; Stirtz, Georgia L.; Dettmer, Ulf; Sortwell, Caryl E.; Feany, Mel B.; Lansbury, Peter; Lapidus, Lisa; Paumier, Katrina L. Share Save
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Increased Efflux of Amyloid-β Peptides through the Blood-Brain Barrier by Muscarinic Acetylcholine Receptor Inhibition Reduces Pathological Phenotypes in Mouse Models of Brain Amyloidosis Paganetti, Paolo; Antoniello, Katia; Devraj, Kavi; Toni, Nicolas; Kieran, Dairin; Madani, Rime; Pihlgren, Maria; Adolfsson, Oskar; Froestl, Wolfgang; Schrattenholz, Andre; Liebner, Stefan; Havas, Daniel; Windisch, Manfred; Cirrito, John R.; Pfeifer, Andrea; Muhs, Andreas Share Save
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Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice Rogers, Kathryn; Felsenstein, Kevin M.; Hrdlicka, Lori; Tu, Zhiming; Albayya, Faris; Lee, Winnie; Hopp, Sarah; Miller, Mary-Jo; Spaulding, Darcie; Yang, Zhiyong; Hodgdon, Hilliary; Nolan, Scott; Wen, Melody; Costa, Don; Blain, Jean-Francois; Freeman, Emily; De Strooper, Bart; Vulsteke, Veerle; Scrocchi, Louise; Zetterberg, Henrik; Portelius, Erik; Hutter-Paier, Birgit; Havas, Daniel; Ahlijanian, Michael; Flood, Dorothy; Leventhal, Liza; Shapiro, Gideon; Patzke, Holger; Chesworth, Richard; Koenig, Gerhard Share Save
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The Acyl-Coenzyme A:Cholesterol Acyltransferase Inhibitor CI-1011 Reverses Diffuse Brain Amyloid Pathology in Aged Amyloid Precursor Protein Transgenic Mice Huttunen, Henri J.; Havas, Daniel; Peach, Camilla; Barren, Cory; Duller, Stephan; Xia, Weiming; Frosch, Matthew P.; Hutter-Paier, Birgit; Windisch, Manfred; Kovacs, Dora M. Share Save
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