Alain Laederach - Publications, H-index & Citations

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Alain Laederach

University of North Carolina

41H-index

186Paper Count

5.7KCitation Count

Published Papers 67

Publication Date

The RNA binding protein ZFP36L2 displays tissue-selective mRNA targeting in mice

RNA Biology

IF3.4

2026-06-21

OAAI

George Stephen Stephenson; Dalia Fleifel; Jeanette Gowen Cook; Alain Laederach; Silvia Beatriz Vieira Ramos

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RNA Structural Ensemble Determinants of -1 Programmed Ribosomal Frameshifting Efficiency Across Coronavirus Evolution

Journal of Molecular Biology

IF4.5

2025-10-28

OAAI

Scott R. Allen; Tamar Schlick; Alain Laederach

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Visualizing RNA structure ensembles by singlemolecule correlated chemical probing

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-10-01

PREAI

Arney, J. Winston; Laederach, Alain; Weeks, Kevin M.

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Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: implications to alternative conformations and their statistical structural analyses

RNA

IF5

2024-07-31

OAAI

Dey, Abhishek; Yan, Shuting; Schlick, Tamar; Laederach, Alain

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Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation

NATURE COMMUNICATIONS

IF15.7

2024-06-20

OAAI

Stewart, Rebeccah K.; Nguyen, Patrick; Laederach, Alain; Volkan, Pelin C.; Sawyer, Jessica K.; Fox, Donald T.

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Colocalization analysis of 3′ UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function

HUMAN MOLECULAR GENETICS

IF3.2

2024-04-03

PREAI

Saferali, Aabida; Kim, Wonji; Xu, Zhonghui; Chase, Robert P.; Cho, Michael H.; Laederach, Alain; Castaldi, Peter J.; Hersh, Craig P.

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Coordinated expression of replication-dependent histone genes from multiple loci promotes histone homeostasis in Drosophila

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2023-11-01

OAAI

Chaubal, Ashlesha; Waldern, Justin M.; Taylor, Colin; Laederach, Alain; Marzluff, William F.; Duronio, Robert J.

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Structural analysis of MALAT1 long noncoding RNA in cells and in evolution

RNA

IF5

2023-02-15

OAAI

Monroy-Eklund, Anais; Taylor, Colin; Weidmann, Chase A.; Burch, Christina; Laederach, Alain

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Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA

NUCLEIC ACIDS RESEARCH

IF13.1

2022-09-15

OAAI

Grayeski, Philip J.; Weidmann, Chase A.; Kumar, Jayashree; Lackey, Lela; Mustoe, Anthony M.; Busan, Steven; Laederach, Alain; Weeks, Kevin M.

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Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility

NUCLEIC ACIDS RESEARCH

IF13.1

2022-09-05

OAAI

Coria, Aaztli; Wienecke, Anastacia; Knight, Michael L.; Desiro, Daniel; Laederach, Alain; Borodavka, Alexander

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Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

ELIFE

IF0

2022-06-13

OAAI

Kumar, Jayashree; Lackey, Lela; Waldern, Justin M.; Dey, Abhishek; Mustoe, Anthony M.; Weeks, Kevin M.; Mathews, David H.; Laederach, Alain; Staley, Jonathan P.

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Distinct responses to rare codons in select Drosophila tissues

ELIFE

IF0

2022-05-06

OAAI

Allen, Scott R.; Stewart, Rebeccah K.; Rogers, Michael; Ruiz, Ivan Jimenez; Cohen, Erez; Laederach, Alain; Counter, Christopher M.; Sawyer, Jessica K.; Fox, Donald T.

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Sequence and tissue targeting specificity of ZFP36L2 reveals Elavl2 as a novel target with co-regulation potential

NUCLEIC ACIDS RESEARCH

IF13.1

2022-04-05

OAAI

Redmon, Ian C.; Ardizzone, Matthew; Hekimoglu, Hilal; Hatfield, Breanne M.; Waldern, Justin M.; Dey, Abhishek; Montgomery, Stephanie A.; Laederach, Alain; Ramos, Silvia B., V

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A novel algorithm for ranking RNA structure candidates

BIOPHYSICAL JOURNAL

IF3.1

2022-01-01

OAAI

Wienecke, Anastacia; Laederach, Alain

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In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei

NUCLEIC ACIDS RESEARCH

IF13.1

2021-11-24

OAAI

Dey, Abhishek; Monroy-Eklund, Anais; Klotz, Kaitlin; Saha, Arpita; Davis, Justin; Li, Bibo; Laederach, Alain; Chakrabarti, Kausik

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Disease-associated human genetic variation through the lens of precursor and mature RNA structure

HUMAN GENETICS

IF3.6

2021-11-06

OAAI

Waldern, Justin M.; Kumar, Jayashree; Laederach, Alain

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Cigarette smoking-associated isoform switching and 3′ UTR lengthening via alternative polyadenylation

GENOMICS

IF3

2021-11-01

OAAI

Xu, Zhonghui; Platig, John; Lee, Sool; Boueiz, Adel; Chase, Rob; Jain, Dhawal; Gregory, Andrew; Suryadevara, Rahul; Berman, Seth; Bowler, Russell; Hersh, Craig P.; Laederach, Alain; Castaldi, Peter J.

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To Knot or Not to Knot: Multiple Conformations of the SARS-CoV-2 Frameshifting RNA Element

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-07-20

OAAI

Schlick, Tamar; Zhu, Qiyao; Dey, Abhishek; Jain, Swati; Yan, Shuting; Laederach, Alain

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Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3′UTR Variation in Chikungunya Virus

JOURNAL OF VIROLOGY

IF3.8

2020-11-23

OAAI

Madden, Emily A.; Plante, Kenneth S.; Morrison, Clayton R.; Kutchko, Katrina M.; Sanders, Wes; Long, Kristin M.; Taft-Benz, Sharon; Cisneros, Marta C. Cruz; White, Ashlyn Morgan; Sarkar, Sanjay; Reynolds, Grace; Vincent, Heather A.; Laederach, Alain; Moorman, Nathanial J.; Heise, Mark T.

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The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2020-03-01

OAAI

Ortega, Victor E.; Li, Xingnan; O'Neal, Wanda K.; Lackey, Lela; Ampleford, Elizabeth; Hawkins, Gregory A.; Grayeski, Philip J.; Laederach, Alain; Barjaktarevic, Igor; Barr, R. Graham; Cooper, Christopher; Couper, David; Han, MeiLan K.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert, III; Peters, Stephen P.; Pirozzi, Cheryl; Rennard, Stephen, I; Woodruff, Prescott G.; Hoffman, Eric A.; Meyers, Deborah A.; Bleecker, Eugene R.

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Research Directions