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M

M.R. Sawaya

University of California Los Angeles

94H-index
630Paper Count
3.6WCitation Count
Published Papers 131
Publication Date
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Structural evidence that RNA contributes to polymorphism of tau amyloid fibrils
erriScience
IF4.1
err2026-03-26
err0
errOAAI
errRomany Abskharon; Yi Xiao Jiang; Michael R. Sawaya; Peng Ge; Jeffrey Zhang; David R. Boyer; Joshua L. Dolinsky; Justin Pi; Duilio Cascio; Feng Guo; David S. Eisenberg
errShare
errSave
Genetic and structural aspects of amyloid diseases
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-10-01
err0
PREAI
errRosenberg, Gregory M.; Murray, Kevin A.; Sawaya, Michael R.; Jiang, Yi Xiao; Geschwind, Daniel H.; Eisenberg, David S.
errShare
errSave
Structural basis for L-isoaspartyl-containing protein recognition by the human PCMTD1 cullin-RING E3 ubiquitin ligase
errJournal of Biological Chemistry
IF3.9
err2025-09-18
err0
errOAAI
errEric Z. Pang; Boyu Zhao; Cameron Flowers; Elizabeth Oroudjeva; Jasmine B. Winter; Vijaya Pandey; Michael R. Sawaya; James Wohlschlegel; Joseph A. Loo; Jose A. Rodriguez; Steven G. Clarke
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errSave
Structural Basis of Heme Scavenging by the ChtA and HtaA Hemophores in Corynebacterium diphtheriae
errJournal of Biological Chemistry
IF3.9
err2025-08-26
err0
errOAAI
errJordan Ford; Andrew K. Goring; Yuri Lee; Megan Chen; Brendan J. Mahoney; Michael R. Sawaya; Hannah S. Shafaat; Joseph A. Loo; Robert T. Clubb
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errSave
How short peptides disassemble tau fibrils in Alzheimer’s disease
errNature
IF48.5
err2025-07-09
err0
PREAI
errKe Hou; Peng Ge; Michael R. Sawaya; Liisa Lutter; Joshua L. Dolinsky; Yuan Yang; Yi Xiao Jiang; David R. Boyer; Xinyi Cheng; Justin Pi; Jeffrey Zhang; Jiahui Lu; Romany Abskharon; Shixin Yang; Zhiheng Yu; Juli Feigon; David S. Eisenberg
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Structural insights into functional regulation of the human CPEB3 prion by an amyloid-forming segment
errStructure
IF4.3
err2025-06-05
err0
errOAAI
errMaria D. Flores; Michael R. Sawaya; David R. Boyer; Samantha Zink; Susanna Tovmasyan; Adrian Saucedo; Logan S. Richards; Chih-Te Zee; Jorge Cardenas; Luana Fioriti; Jose A. Rodriguez
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errSave
Amyloid Oligomers: Expediting Crystal Growth and Revisiting the Corkscrew Structures
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-05-21
err0
PREAI
errHirschbeck, Sarah S.; Sawaya, Michael R.; Lindberg, Edward T.; Limbach, Miranda N.; Jang, Joshua H.; Lazar Cantrell, Kristi L.; Eisenberg, David S.
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errSave
Liganded magnetic nanoparticles for magnetic resonance imaging of α-synuclein
errNPJ PARKINSONS DISEASE
IF8.2
err2025-04-23
err0
errOAAI
errPan, Hope; Balbirnie, Melinda; Hou, Ke; Maria, Naomi S. Sta; Sahay, Shruti; Denver, Paul; Lepore, Stefano; Jones, Mychica; Zuo, Xiaohong; Zhu, Chunni; Mirbaha, Hilda; Shahpasand-Kroner, Hedieh; Mekkittikul, Marisa; Lu, Jiahui; Hu, Carolyn J.; Cheng, Xinyi; Abskharon, Romany; Sawaya, Michael R.; Williams, Christopher K.; Vinters, Harry V.; Jacobs, Russell E.; Harris, Neil G.; Cole, Gregory M.; Frautschy, Sally A.; Eisenberg, David S.
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A genomic analysis reveals the diversity of cellulosome displaying bacteria
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2024-10-30
err1
errOAAI
errMinor, Christine M.; Takayesu, Allen; Ha, Sung Min; Salwinski, Lukasz; Sawaya, Michael R.; Pellegrini, Matteo; Clubb, Robert T.
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errSave
D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease
errSCIENCE ADVANCES
IF12.5
err2024-05-03
err2
errOAAI
errHou, Ke; Pan, Hope; Shahpasand-Kroner, Hedieh; Hu, Carolyn; Abskharon, Romany; Seidler, Paul; Mekkittikul, Marisa; Balbirnie, Melinda; Lantz, Carter; Sawaya, Michael R.; Dolinsky, Joshua L.; Jones, Mychica; Zuo, Xiaohong; Loo, Joseph A.; Frautschy, Sally; Cole, Greg; Eisenberg, David S.
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errSave
Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-02-01
err2
errOAAI
errLu, Jiahui; Ge, Peng; Sawaya, Michael R.; Hughes, Michael P.; Boyer, David R.; Cao, Qin; Abskharon, Romany; Cascio, Duilio; Tayeb-Fligelman, Einav; Eisenberg, David S.
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errSave
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
errNATURE COMMUNICATIONS
IF15.7
err2024-01-17
err11
errOAAI
errNguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; Pedretti, Rose; Fernandez-Ramirez, Maria del Carmen; Singh, Preeti; Pekala, Maja; Hernandez, Luis O. Cabrera; Kumar, Siddharth; Lemoff, Andrew; Gonzalez-Prieto, Roman; Sawaya, Michael R.; Eisenberg, David S.; Benson, Merrill Douglas; Saelices, Lorena
errShare
errSave
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method
errPNAS NEXUS
IF3.8
err2023-11-20
err0
errOAAI
errRosenberg, Gregory M.; Abskharon, Romany; Boyer, David R.; Ge, Peng; Sawaya, Michael R.; Eisenberg, David S.
errShare
errSave
Racemic Peptides from Amyloid β and Amylin Form Rippled β-Sheets Rather Than Pleated β-Sheets
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-11-16
err3
PREAI
errHazari, Amaruka; Sawaya, Michael R.; Sajimon, Maria; Vlahakis, Niko; Rodriguez, Jose; Eisenberg, David; Raskatov, Jevgenij A.
errShare
errSave
Structure- based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-10-06
err12
errOAAI
errAbskharon, Romany; Pan, Hope; Sawaya, Michael R.; Seidler, Paul M.; Olivares, Eileen J.; Chen, Yu; Murray, Kevin A.; Zhang, Jeffrey; Lantz, Carter; Bentzel, Megan; Boyer, David R.; Cascio, Duilio; Nguyen, Binh A.; Hou, Ke; Cheng, Xinyi; Pardon, Els; Williams, Christopher K.; Nana, Alissa L.; V. Vinters, Harry; Spina, Salvatore; Grinberg, Lea T.; Seeley, William W.; Steyaert, Jan; Glabe, Charles G.; Loo, Rachel R. Ogorzalek; Loo, Joseph A.; Eisenberg, David S.
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errSave
Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-09-05
err12
errOAAI
errCastells-Graells, Roger; Meador, Kyle; Arbing, Mark A.; Sawaya, Michael R.; Gee, Morgan; Cascio, Duilio; Gleave, Emma; Debreczeni, Judit E.; Breed, Jason; Leopold, Karoline; Patel, Ankoor; Jahagirdar, Dushyant; Lyons, Bronwyn; Subramaniam, Sriram; Phillips, Chris; Yeates, Todd O.
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errSave
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils
errNATURE COMMUNICATIONS
IF15.7
err2023-04-25
err9
errOAAI
errTayeb-Fligelman, Einav; Bowler, Jeannette T.; Tai, Christen E. E.; Sawaya, Michael R.; Jiang, Yi Xiao; Garcia, Gustavo; Griner, Sarah L.; Cheng, Xinyi; Salwinski, Lukasz; Lutter, Liisa; Seidler, Paul M.; Lu, Jiahui; Rosenberg, Gregory M.; Hou, Ke; Abskharon, Romany; Pan, Hope; Zee, Chih-Te; Boyer, David R.; Li, Yan; Anderson, Daniel H.; Murray, Kevin A.; Falcon, Genesis; Cascio, Duilio; Saelices, Lorena; Damoiseaux, Robert; Arumugaswami, Vaithilingaraja; Guo, Feng; Eisenberg, David S.
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errSave
Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-04-01
err10
errOAAI
errSun, Chuanqi; Zhou, Kang; DePaola, Peter; Shin, Woo Shik; Hillyer, Trae; Sawaya, Michael R.; Zhu, Ruowei; Peng, Chao; Zhou, Z. Hong; Jiang, Lin
errShare
errSave
Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED
errACS BIO & MED CHEM AU
IF4.3
err2023-02-23
err9
errOAAI
errRichards, Logan S.; Flores, Maria D.; Millan, Claudia; Glynn, Calina; Zee, Chih-Te; Sawaya, Michael R.; Gallagher-Jones, Marcus; Borges, Rafael J.; Uson, Isabel; Rodriguez, Jose A.
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errSave
Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-10-01
err6
errOAAI
errBowler, Jeannette T.; Sawaya, Michael R.; Boyer, David R.; Cascio, Duilio; Bali, Manya; Eisenberg, David S.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Omar M. Yaghi
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Daniel H. Geschwind
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K. N. Houk
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Kurt Wüthrich
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