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Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using Liu, Siyan; Hamilton, Marisa C.; Cowart, Thomas; Barrera, Alejandro; Bounds, Lexi R.; Nelson, Alexander C.; Dornbaum, Sophie F.; Riley, Julia W.; Doty, Richard W.; Allen, Andrew S.; Crawford, Gregory E.; Majoros, William H.; Gersbach, Charles A. Share Save
Single-nucleus multi-omics of Parkinson's disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks Shwab, E. Keats; Gingerich, Daniel C.; Man, Zhaohui; Gamache, Julia; Garrett, Melanie E.; Crawford, Gregory E.; Ashley-Koch, Allison E.; Serrano, Geidy E.; Beach, Thomas G.; Lutz, Michael W.; Chiba-Falek, Ornit Share Save
Chromatin Remodeling in Patient-Derived Colorectal Cancer Models Xiang, Kun; Wang, Ergang; Mantyh, John; Rupprecht, Gabrielle; Negrete, Marcos; Sanati, Golshid; Hsu, Carolyn; Randon, Peggy; Dohlman, Anders; Kretzschmar, Kai; Bose, Shree; Giroux, Nicholas; Ding, Shengli; Wang, Lihua; Balcazar, Jorge Prado; Huang, Qiang; Sundaramoorthy, Pasupathi; Xi, Rui; Mccall, Shannon Jones; Wang, Zhaohui; Jiang, Chongming; Kang, Yubin; Kopetz, Scott; Crawford, Gregory E.; Lipkin, Steven M.; Wang, Xiao-Fan; Clevers, Hans; Hsu, David; Shen, Xiling Share Save
Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids Capauto, Davide; Wang, Yifan; Wu, Feinan; Norton, Scott; Mariani, Jessica; Inoue, Fumitaka; Crawford, Gregory E.; Ahituv, Nadav; Abyzov, Alexej; Vaccarino, Flora M. Share Save
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Single cell profiling at the maternal-fetal interface reveals a deficiency of PD-L1+ non-immune cells in human spontaneous preterm labor Liu, Xiao; Aneas, Ivy; Sakabe, Noboru; Anderson, Rebecca L.; Billstrand, Christine; Paz, Cristina; Kaur, Harjot; Furner, Brian; Choi, Seong; Prichina, Adriana Y.; Enninga, Elizabeth Ann L.; Dong, Haidong; Murtha, Amy; Crawford, Gregory E.; Kessler, John A.; Grobman, William; Nobrega, Marcelo A.; Rana, Sarosh; Ober, Carole Share Save
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Profiling the quantitative occupancy of myriad transcription factors across conditions by modeling chromatin accessibility data Luo, Kaixuan; Zhong, Jianling; Safi, Alexias; Hong, Linda K.; Tewari, Alok K.; Song, Lingyun; Reddy, Timothy E.; Ma, Li; Crawford, Gregory E.; Hartemink, Alexander J. Share Save
Enhancer selection dictates gene expression responses in remote organs during tissue regeneration Sun, Fei; Ou, Jianhong; Shoffner, Adam R.; Luan, Yu; Yang, Hongbo; Song, Lingyun; Safi, Alexias; Cao, Jingli; Yue, Feng; Crawford, Gregory E.; Poss, Kenneth D. Share Save
Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity Murthy, Preetish Kadur Lakshminarasimha; Xi, Rui; Arguijo, Diana; Everitt, Jeffrey, I; Kocak, Dewran D.; Kobayashi, Yoshihiko; Bozec, Aline; Vicent, Silvestre; Ding, Shengli; Crawford, Gregory E.; Hsu, David; Tata, Purushothama Rao; Reddy, Timothy; Shen, Xiling Share Save
Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer's disease brains Barrera, Julio; Song, Lingyun; Gamache, Julia E.; Garrett, Melanie E.; Safi, Alexias; Yun, Young; Premasinghe, Ivana; Sprague, Daniel; Chipman, Danielle; Li, Jeffrey; Fradin, Helene; Soldano, Karen; Gordan, Raluca; Ashley-Koch, Allison E.; Crawford, Gregory E.; Chiba-Falek, Ornit Share Save
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis Wang, Lihua; Wang, Ergang; Prado Balcazar, Jorge; Wu, Zhenzhen; Xiang, Kun; Wang, Yi; Huang, Qiang; Negrete, Marcos; Chen, Kai-Yuan; Li, Wei; Fu, Yujie; Dohlman, Anders; Mines, Robert; Zhang, Liwen; Kobayashi, Yoshihiko; Chen, Tianyi; Shi, Guizhi; Shen, John Paul; Kopetz, Scott; Tata, Purushothama Rao; Moreno, Victor; Gersbach, Charles; Crawford, Gregory; Hsu, David; Huang, Emina; Bu, Pengcheng; Shen, Xiling Share Save
Targeted long-read sequencing identifies missing disease-causing variation Miller, Danny E.; Sulovari, Arvis; Wang, Tianyun; Loucks, Hailey; Hoekzema, Kendra; Munson, Katherine M.; Lewis, Alexandra P.; Fuerte, Edith P. Almanza; Paschal, Catherine R.; Walsh, Tom; Thies, Jenny; Bennett, James T.; Glass, Ian; Dipple, Katrina M.; Patterson, Karynne; Bonkowski, Emily S.; Nelson, Zoe; Squire, Audrey; Sikes, Megan; Beckman, Erika; Bennett, Robin L.; Earl, Dawn; Lee, Winston; Allikmets, Rando; Perlman, Seth J.; Chow, Penny; Hing, Anne, V; Wenger, Tara L.; Adam, Margaret P.; Sun, Angela; Lam, Christina; Chang, Irene; Zou, Xue; Austin, Stephanie L.; Huggins, Erin; Safi, Alexias; Iyengar, Apoorva K.; Reddy, Timothy E.; Majoros, William H.; Allen, Andrew S.; Crawford, Gregory E.; Kishnani, Priya S.; King, Mary-Claire; Cherry, Tim; Chong, Jessica X.; Bamshad, Michael J.; Nickerson, Deborah A.; Mefford, Heather C.; Doherty, Dan; Eichler, Evan E. Share Save
Integrated chromatin and transcriptomic profiling of patient-derived colon cancer organoids identifies personalized drug targets to overcome oxaliplatin resistance Tung, Kuei-Ling; Chen, Kai-Yuan; Negrete, Marcos; Chen, Tianyi; Safi, Alexias; Aljamal, Abed Alhalim; Song, Lingyun; Crawford, Gregory E.; Ding, Shengli; Hsu, David S.; Shen, Xiling Share Save
Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth Sakabe, Noboru J.; Aneas, Ivy; Knoblauch, Nicholas; Sobreira, Debora R.; Clark, Nicole; Paz, Cristina; Horth, Cynthia; Ziffra, Ryan; Kaur, Harjot; Liu, Xiao; Anderson, Rebecca; Morrison, Jean; Cheung, Virginia C.; Grotegut, Chad; Reddy, Timothy E.; Jacobsson, Bo; Hallman, Mikko; Teramo, Kari; Murtha, Amy; Kessler, John; Grobman, William; Zhang, Ge; Muglia, Louis J.; Rana, Sarosh; Lynch, Vincent J.; Crawford, Gregory E.; Ober, Carole; He, Xin; Nobrega, Marcelo A. Share Save
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Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation Keele, Gregory R.; Quach, Bryan C.; Israel, Jennifer W.; Chappell, Grace A.; Lewis, Lauren; Safi, Alexias; Simon, Jeremy M.; Cotney, Paul; Crawford, Gregory E.; Valdar, William; Rusyn, Ivan; Furey, Terrence S. Share Save
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