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Patrick Tam

Children's Medical Research Institute

85H-index
572Paper Count
2.5WCitation Count
Published Papers 83
Publication Date
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DNA methylation reprogramming in marsupial embryos is restricted to the extraembryonic lineage
errNature Communications
IF15.7
err2026-06-15
err0
errOAAI
errAllegra Angeloni; Jillian M. Hammond; Timothy J. Peters; Andre L. M. Reis; Leah Kemp; Timothy G. Amos; Hasindu Gamaarachchi; Sam Humphries; Lynda A. Wilmott; Suranjana Pal; V. Pragathi Masamsetti; Megan Weatherstone; Chi Kin Ip; Karina Pazaky; Alice Steel; Ruth Lyons; Elly D. Walters; Ning Liu; Patrick Tam; Jose M. Polo; Paul D. Waters; Susan J. Clark; Linda J. Richards; Andrew D. Smith; Heather J. Lee; Ira W. Deveson; Oliver W. Griffith; Ksenia Skvortsova
errShare
errSave
Retinoic acid drives cell fate specification, maturation and retinal regionality in human retinal organoids
errNature Communications
IF15.7
err2026-04-25
err0
errOAAI
errBenjamin Y. Lim; Carissa Chen; Anna Fredericks; Elham Nilli; Santiago Mesa Mora; Megan Weatherstone; To Ha Loi; Peter Newman; Nader Aryamanesh; Hala Zreiqat; Patrick Tam; Pengyi Yang; Anai Gonzalez-Cordero
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errSave
Neural crest cell-derived DKK1 and NEDD4 modulate Wnt signalling in the second heart field to orchestrate outflow tract development
errNature Communications
IF15.7
err2026-01-22
err0
errOAAI
errSophie Wiszniak; Dimuthu Alankarage; Iman Lohraseb; Ceilidh Marchant; Genevieve Secker; Deepti Domingo; Jasmine Hartmann; Tianyang Zhang; Wendy Parker; John Toubia; Melissa White; Sandra Piltz; Markus Tondl; Eleni Giannoulatou; David Winlaw; Gillian M. Blue; Patrick P. L. Tam; Paul Thomas; Natasha Harvey; Sally L. Dunwoodie; Quenten Schwarz
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errSave
Constructing the spatiotemporal atlas of single-cell lineage trajectories in stereotypic biological structures
errISCIENCE
IF4.1
err2026-01-16
err0
PREAI
errWang, Ran; Yang, Xianfa; Lian, Chengfei; Wang, Jianjie; Chen, Jiehui; Qian, Yun; Xu, Yaochen; Wang, Liantang; Marioni, John C.; Tam, Patrick P. L.; Jing, Naihe
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errSave
Integrated multi-omic atlas reveals the hierarchy of spatiotemporal regulatory networks of mouse gastrulation
errNature Communications
IF15.7
err2026-01-12
err0
errOAAI
errXianfa Yang; Bingbing Xie; Penglei Shen; Yingying Chen; Chunjie Li; Fengxiang Tan; Yumeng Yang; Yun Yang; Rui Song; Panpan Mi; Zhiwen Liu; Mingzhu Wen; Patrick P. L. Tam; Shengbao Suo; Naihe Jing
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errSave
Functional attributes of the anterior mesendoderm in patterning the anterior neural structures during head formation in the mouse
errCELLS & DEVELOPMENT
IF2
err2025-12-01
err1
PREAI
errTam, Patrick P. L.; Masamsetti, Pragathi
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errSave
Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells
errStem Cell Reports
IF5.1
err2025-08-05
err0
errOAAI
errChang Liu; Ran Wang; Zhisong He; Pierre Osteil; Emilie Wilkie; Xianfa Yang; Jun Chen; Guizhong Cui; Wenke Guo; Yingying Chen; Guangdun Peng; Patrick P.L. Tam; Naihe Jing
errShare
errSave
MIXL1 activation in endoderm differentiation of human induced pluripotent stem cells
errSTEM CELL REPORTS
IF5.1
err2025-05-01
err0
errOAAI
errOsteil, Pierre; Withey, Sarah; Santucci, Nicole; Aryamanesh, Nader; Pang, Ignatius; Salehin, Nazmus; Sun, Jane; Qin, Annie; Su, Jiayi; Knowles, Hilary; Li, Xiucheng Bella; Cai, Simon; Wolvetang, Ernst; Tam, Patrick P. L.
errShare
errSave
Pluripotent cell states and fates in human embryo models
errDEVELOPMENT
IF3.6
err2025-04-02
err0
PREAI
errSozen, Berna; Tam, Patrick P. L.; Pera, Martin F.
errShare
errSave
Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo
errDevelopmental Cell
IF8.7
err2025-03-24
err0
PREAI
errV. Pragathi Masamsetti; Nazmus Salehin; Hani Jieun Kim; Nicole Santucci; Megan Weatherstone; Riley McMahon; Lee L. Marshall; Hilary Knowles; Jane Sun; Josh B. Studdert; Nader Aryamanesh; Ran Wang; Naihe Jing; Pengyi Yang; Pierre Osteil; Patrick P.L. Tam
errShare
errSave
Human developmental biology - a global perspective
errDEVELOPMENT
IF3.6
err2024-09-16
err1
PREAI
errClark, Amander T.; Goolam, Mubeen; Hanna, Jacob H.; Long, Katie; Nicol, Dianne; Petropoulos, Sophie; Saitou, Mitinori; Tam, Patrick P. L.; Wang, Hongmei
errShare
errSave
Criteria for the standardization of stem-cell-based embryo models
errNATURE CELL BIOLOGY
IF19.1
err2024-09-02
err2
PREAI
errMartinez Arias, Alfonso; Rivron, Nicolas; Moris, Naomi; Tam, Patrick; Alev, Cantas; Fu, Jianping; Hadjantonakis, Anna-Katerina; Hanna, Jacob H.; Minchiotti, Gabriella; Pourquie, Olivier; Sheng, Guojun; Solnica Krezel, Liliana; Veenvliet, Jesse V.; Warmflash, Aryeh
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errSave
Trans-omic profiling uncovers molecular controls of early human cerebral organoid formation
errCELL REPORTS
IF6.9
err2024-05-01
err0
errOAAI
errChen, Carissa; Lee, Scott; Zyner, Katherine G.; Fernando, Milan; Nemeruck, Victoria; Wong, Emilie; Marshall, Lee L.; Wark, Jesse R.; Aryamanesh, Nader; Tam, Patrick P. L.; Graham, Mark E.; Gonzalez-Cordero, Anai; Yang, Pengyi
errShare
errSave
Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm
errDEVELOPMENTAL CELL
IF8.7
err2024-03-01
err1
PREAI
errWu, Zhixuan; Shen, Sophie; Mizikovsky, Dalia; Cao, Yuanzhao; Naval-Sanchez, Marina; Tan, Siew Zhuan; Alvarez, Yanina D.; Sun, Yuliangzi; Chen, Xiaoli; Zhao, Qiongyi; Kim, Daniel; Yang, Pengyi; Hill, Timothy A.; Jones, Alun; Fairlie, David P.; Pebay, Alice; Hewitt, Alex W.; Tam, Patrick P. L.; White, Melanie D.; Nefzger, Christian M.; Palpant, Nathan J.
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errSave
Time space and single-cell resolved tissue lineage trajectories and laterality of body plan at gastrulation
errNATURE COMMUNICATIONS
IF15.7
err2023-09-14
err4
errOAAI
errWang, Ran; Yang, Xianfa; Chen, Jiehui; Zhang, Lin; Griffiths, Jonathan A.; Cui, Guizhong; Chen, Yingying; Qian, Yun; Peng, Guangdun; Li, Jinsong; Wang, Liantang; Marioni, John C.; Tam, Patrick P. L.; Jing, Naihe
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errSave
Rat epiblast-derived stem cells recapitulate the attributes of pre-gastrulation epiblast
errCELL REPORTS METHODS
IF4.5
err2023-08-01
err0
errOAAI
errMasamsetti, V. Pragathi; Tam, Patrick P. L.
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errSave
Technical challenges of studying early human development
errDEVELOPMENT
IF3.6
err2023-06-01
err15
errOAAI
errRugg-Gunn, Peter J.; Moris, Naomi; Tam, Patrick P. L.
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errSave
Programming of Multicellular Patterning with Mechano-Chemically Microstructured Cell Niches
errADVANCED SCIENCE
IF14.1
err2023-03-30
err5
errOAAI
errNewman, Peter L. H.; Yip, Queenie; Osteil, Pierre; Anderson, Tim A.; Sun, Jane Q. J.; Kempe, Daryan; Biro, Mate; Shin, Jae-Won; Tam, Patrick P. L.; Zreiqat, Hala
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errSave
Generation of Mice Deficient in both KLF3/BKLF and KLF8 Reveals a Genetic Interaction and a Role for These Factors in Embryonic Globin Gene Silencing
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err41
errOAAI
errFunnell, Alister P. W.; Mak, Ka Sin; Twine, Natalie A.; Pelka, Gregory J.; Norton, Laura J.; Radziewic, Tania; Power, Melinda; Wilkins, Marc R.; Bell-Anderson, Kim S.; Fraser, Stuart T.; Perkins, Andrew C.; Tam, Patrick P.; Pearson, Richard C. M.; Crossley, Merlin
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errSave
TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err23
errOAAI
errFan, Xiaochen; Waardenberg, Ashley J.; Demuth, Madeleine; Osteil, Pierre; Sun, Jane Q. J.; Loebel, David A. F.; Graham, Mark; Tam, Patrick P. L.; Fossat, Nicolas
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errSave

Research Directions

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Co-authors
Cooperation Journals
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Janet Rossant
H-index: 149 · Papers: 1.1K
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David W. Russell
H-index: 144 · Papers: 860
S
Sarah A. Teichmann
H-index: 141 · Papers: 677
M
Manolis Kellis
H-index: 139 · Papers: 1.1K
P
Pak C. Sham
H-index: 135 · Papers: 1.1K
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