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Cell Death Discovery 封面图

Cell Death Discovery

IF7
论文数3867
被引数13231
期刊论文 3867
发表时间
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PHF2-mediated hydroxylation destabilizes NFATc1 to restrain osteoclastogenesisPHF2介导的羟基化使NFATc1失稳以抑制破骨细胞生成
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delete2026-11-03
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deleteJooseung Lee; Min Young Lee; Hye-Jin Kim; Geon Ho Moon; Jengmin Kang; Hyeryeon Jung; Mi Reu Jeong; Jong-Wan Park; Eugene C. Yi; Alan Jung Park; Seung Hyeok Seok; Yang-Sook Chun
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MCP-1 licenses mesenchymal stem cells for T-cell-supportive functionMCP-1授权间充质干细胞发挥T细胞支持功能
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deleteYifan He; Shoucheng Chen; Haotian Liu; Xiaoyi Lai; Qianyi Shi; Jiaxin Xie; Yan Qu; Bowen Meng; Chaoran Fu; Benyi Yang; Weiying Huang; Songtao Shi; Yang Cao
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Excess bile acid impairs oocyte maturation through H1.2-mediated chromatin and epigenetic remodeling过量胆汁酸通过H1.2介导的染色质和表观遗传重塑损害卵母细胞成熟
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deleteMing Gao; Hengjie Wang; Yueshuai Guo; Jiashuo Li; Yiqiu Wu; Shoubin Tang; Jiaqian Ju; Longsen Han; Juan Ge; Lu Qi; Qiang Wang; Ling Gu
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miRNA cargo from pleural mesothelioma-derived extracellular vesicles reprograms fibroblasts toward an inflammatory CAF-like phenotype源自胸膜间皮瘤衍生的外泌体的miRNA货物使成纤维细胞重编程为炎症性CAF样表型
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delete2026-11-01
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deleteVivek Dharwal; Winston Lay; Richard Zelei; Ali Azimi; Ellen Donohoe; Lucy Wang; Tim Huang; Ling Zhuang; Georges Grau; Stephen Clarke; Steven Kao; Fatemeh Vafaee; Zaklina Kovacevic; Elham Hosseini-Beheshti
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JNK-mediated RAD18 phosphorylation promotes colorectal cancer progression through K48-linked ubiquitination and degradation of SFNJNK介导的RAD18磷酸化通过K48连接的泛素化和SFN降解促进结直肠癌进展
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deleteHongqiang Zhang; Yang Chen; Zhenling Wang; Yong Wang; Zhizheng Zhang; Hengyang Shen; Min Zhao; Ying Tong; Changzhi Huang; Cong Chen; Zan Fu
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DYRK1A coordinates tumor–stroma secretory programs that promote an immunosuppressive microenvironment in pancreatic cancerDYRK1A协调促进胰腺癌免疫抑制微环境的肿瘤-基质分泌程序
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deleteSilvia Pascual-Sabater; Sushmita Varhadi; Marta Celma-Arrufat; Chiara Di Vona; Jacopo Boni; Cristina Fillat; Susana de la Luna
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STF-62247 induces a non-canonical, caspase-independent cell death in ccRCC associated with autophagic and lysosomal dysfunctionSTF-62247诱导一种非经典的、半胱天冬酶非依赖性的细胞死亡，该死亡与ccRCC相关的自噬和溶酶体功能障碍有关
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deleteMathieu Johnson; Cai Smyth; Sophie E. Landry; Chloé Michaud; Patric M. Page; Kevin Caissie; Sandra Turcotte
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A syngeneic mouse model of metastatic hormone-naive prostate cancer provides a platform for studying combination immunotherapy同种异体小鼠模型为研究转移性激素未治疗的前列腺癌提供了联合免疫治疗的平台
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deleteVictoria Cid-Centelles; Jaione Auzmendi-Iriarte; Ianire Astobiza; Onintza Carlevaris; Ivana Rondon-Lorefice; Maria Ponce-Rodriguez; Marc Guiu; Ivana Hermanova; Leire Egia-Mendikute; Saioa Garcia-Longarte; Amaia Ercilla-Eguiarte; Natalia Martin-Martin; Amaia Zabala-Letona; Asis Palazon; Roger R. Gomis; Isabel Mendizabal; Arkaitz Carracedo; Marco Piva
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DAPK1 orchestrates Lipin1-dependent fatty acid oxidation to enhance ferroptotic susceptibility in colorectal cancerDAPK1调控Lipin1依赖性脂肪酸氧化以增强结直肠癌的铁死亡易感性
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deleteYuan Tian; Jiao Pang; Woo Jung Kim; Jiwon Kim; Se Hwan Mun; Hai-Anh Nguyen; Jinju Kim; Gyu Hwan Hyun; Hendra Mahakam Putra; Keumbee Min; Sora Han; Young Yang
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Redox Orchestration of organ regeneration器官再生的氧化还原调控
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deleteYang Liu; Yi Zhu; Hao Cai; Tong Xu; Zhihang Zuo; Yujia Teng; Heng Wang; Xuebing Yan; Binxu Yin
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PRMT6–SIRT5–HADHA signaling safeguards osteoblasts from R-loop-induced DNA damage during age-related osteoporosisPRMT6–SIRT5–HADHA信号通路在年龄相关骨质疏松中保护成骨细胞免受R环诱导的DNA损伤
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deleteXinman Song; Shanshan Huang; Xiaoxuan Guo; Chunna Gao; Guangna Yue; Lifei Chen; Zhaohan Du; Jia Xu; Xinquan Jiang; Xiaowei Liu; Shaohai Wang
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Pharmacologic CFTR potentiation attenuates alveolar epithelial senescence and experimental pulmonary fibrosis药理学CFTR增强剂可减轻肺泡上皮细胞衰老和实验性肺纤维化
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deleteShuang Wu; Liyuan Yang; Yabo Ma; Zheqing Hu; Lingling Jinag; Aleksandra Tata; Jing Xue; Jing Wang; Kyhler D. Campbell; Cheng Wang; Juan Chen; Yujiong Wang; John F. Engelhardt; Xiaoming Liu
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NF-κB–mediated chemoresistance emerges from distorted fallopian tube cell-state trajectory in ovarian cancerNF-κB介导的化疗耐药性源于卵巢癌中扭曲的输卵管细胞状态轨迹
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deleteAnna Pirttikoski; Shabnaz Koochakkhani; Laura Gall-Mas; Wojciech Senkowski; David Fontaneda-Arenas; Jun Dai; Matías Marín Falco; Erdogan Pekcan Erkan; Johanna Hynninen; Krister Wennerberg; Anna Vähärautio
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MTRF1 reverses cisplatin resistance in bladder cancer by competitively disrupting OTUB1-mediated deubiquitination of SLC25A5 to trigger ferroptosisMTRF1通过竞争性破坏OTUB1介导的SLC25A5的去泛素化来逆转膀胱癌中的顺铂耐药性以触发铁死亡
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deleteJun Dai; Chi Phuong Do; Jingyi Huang; Siwei Xing; Chen Fang
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USP24 and NF-κB formed a positive regulatory loop increases BMP4 to induce cardiac fibrosis during lung cancer progressionUSP24与NF-κB形成正反馈调控环路，增加BMP4以诱导肺癌进展过程中的心脏纤维化
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deleteYung-Ching Chen; Tran Thu Huong; Shao-An Wang; Shun-Ping Chang; Wei-Ting Chang; Wen-Chang Chang; Ping-Yen Liu; Jan-Jong Hung
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Colon cancer cells survive and recover proliferation under prolonged glucose deprivation结肠癌细胞在长期葡萄糖剥夺条件下存活并恢复增殖
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deleteBar Levi; Subha Ranjan Das; Raichel Cohen-Harazi; Brajesh Kumar Savita; Hadas Fulman-Levy; Bidisha Sharma; Ifat Abramovich; Eyal Gottlieb; Ivan Molodtsov; Michael Sherman; Igor Koman; Elimelech Nesher
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Selective integration of transplanted mitochondria drive sustained metabolic and functional rescue in MELAS endothelial cells through enhanced protein translation移植线粒体的选择性整合通过增强蛋白质翻译，在MELAS内皮细胞中驱动持续性的代谢和功能恢复
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deleteQian Hua Phua; Jeremy Kah Sheng Pang; Hongjie Zhang; Winanto Ng; Xiaoxiao Ma; Kay En Low; Shi Yan Ng; Boon Seng Soh
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Differential redox-mitochondrial adaptation to ultra-high-dose-rate irradiation in astrocytes and glioma cells星形胶质细胞和胶质瘤细胞中差异化的氧化还原-线粒体适应对超高剂量率照射的反应
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deleteGiulia Rosini; Elisa De Santis; Riccardo Nieri; Matteo Paolini; Filippo Rossi; Silverio Sbrana; Esther Ciarrocchi; Andrea Cavalieri; Fabiola Paiar; Fabio Di Martino; Eleonora Vannini; Mario Costa; Beatrice D’Orsi
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A lncRNA–miRNA axis regulates the balance between proliferative and invasive states in melanoma长链非编码RNA–微小RNA轴调控黑色素瘤中增殖状态和侵袭状态的平衡
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deleteLucrezia De Santis; Alessandro De Santis; Vito Antonio Amico; Sofia Testarmata; Alessandra Fragale; Lucia Gabriele; Carlo Presutti
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4-Octyl itaconate promotes dendritic cell tolerogenic properties via suppressing STING signaling to delay lupus onset4-辛基衣康酸酯通过抑制STING信号通路促进树突状细胞的耐受性特征以延缓狼疮发作
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deleteLihua Zhu; Xue Wang; Luyao Yu; Zongxia Ge; Bo Zhu
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