logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
返回期刊详情
European Journal of Medicinal Chemistry 封面图

European Journal of Medicinal Chemistry

IF5.9
论文数16946
被引数59745
期刊论文 16946
发表时间
delete
Design, synthesis, and biological evaluation of diosgenin derivatives containing arylsulfonamide moieties as anti-osteosarcoma agents through modulation of the Hippo pathway含芳基磺酰胺基团的薯蓣皂苷元衍生物的设计、合成及其通过调控Hippo通路作为抗骨肉瘤剂的生物评价
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-29
delete0
PREAI
deleteXiao-Jie Si; Bing-Han Yan; Xin-Chen Zhan; Jun-Li Chang; Xing-Yuan Sun; Guo-Qiang Lin; Yong-Jun Wang; Yan-Ping Yang; Chen-Guo Feng
delete分享
delete收藏
Design, synthesis and in vitro anti-tubercular evaluation of novel 5-Heterocycle substituted-5, 6-dihydropyrido[2,3-d]pyrimidine-4, 7(3H, 8H)-dione compounds新型5-杂环取代-5,6-二氢吡啶[2,3-d]嘧啶-4,7(3H,8H)-二酮类化合物的设计、合成及in vitro抗结核活性评价
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-29
delete0
PREAI
deleteLianqi Sun; Lei Zhang; Bairun Yang; Shibo Kou; Bin Wang; Yi Hong; Zhuorong Li; Yu Lu
delete分享
delete收藏
Discovery of a highly potent DDR1/2 inhibitor with good kinase selectivity and strong anti-inflammatory efficacy in a mouse model of acute kidney injury在急性肾损伤小鼠模型中发现一种高活性DDR1/2抑制剂，其具有优良的激酶选择性和强大的抗炎效果
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-29
delete0
PREAI
deleteMichael Härter; Michael Koch; Jan Dreher; Anja Giese; Fabian Göricke; Klemens Lustig; Jürgen Klar; Ambra Pozzi; Corina M. Borza
delete分享
delete收藏
Divergently Synthesis and Antifibrotic Evaluation of Fucosylated Chondroitin Sulfate Oligosaccharides with Defined Sulfation Patterns发散式合成及具有明确硫酸化模式的岩藻糖基硫酸软骨素寡糖的抗纤维化评价
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-29
delete0
PREAI
deleteDan Li; Guoqing Yang; Yu Yang; Shanshan Chen; Ran Wang; Changlun Lv; Shengzhou Ma; Shixin Wang; Ximing Xu; Xuan Xia; Chunxia Li
delete分享
delete收藏
Structure-activity relationship and target identification of marine anthranilamides as anti-inflammatory agents海洋邻氨基苯甲酰胺类化合物作为抗炎剂的结构-活性关系及靶点识别
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-28
delete0
PREAI
deleteYue Zhou; Guifeng Ji; Yanmei Chen; Liangzhou Li; Xiangyu Wang; Ahmed Naseer; Xuanyi Xue; Jichen Yang; Tong Lu; Lujie Wang; Zhiqing Liu; Pingyuan Wang; Chang-Yun Wang
delete分享
delete收藏
Reimagining Natural Products: Tools and Approaches to Create New Chemical Entities for Drug Discovery重新构想天然产物：用于药物发现中新化学实体的创建工具与方法
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-27
delete0
PREAI
deleteAtef Emad; Anglo Beshay; Samar Hamdi; Mohamed A. Moneim; Omnia A. Al-wdan; Ahmed A. Nasser; Hassan Marei; Esraa Ahmed; Mohamed A. Seleem
delete分享
delete收藏
Computationally Driven Design and Validation of Piperazine-Bridged Phthalimide Derivatives as Multifunctional Agents against Alzheimer’s Disease计算驱动的设计与验证：哌嗪桥联邻苯二甲酰亚胺衍生物作为抗阿尔茨海默病多功能药物的研究
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-27
delete0
PREAI
deleteBharti Devi; Kailash Jangid; Pooja Temgire; Naveen Kumar; Suresh Thareja; Puneet Kumar; Vinod Kumar
delete分享
delete收藏
Imidazopyridines as Anticancer Chemotypes: Structure-Activity Relationships, Molecular Targets, and Lead Optimization Opportunities咪唑吡啶作为抗癌化学类型：构效关系、分子靶点及先导化合物优化机遇
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-27
delete0
PREAI
deleteFirdoos Ahmad Sofi; Samima Khatun; Pravin J. Wanjari
delete分享
delete收藏
Design and Synthesis of Carvedilol-Derived Dual-Functional Adjuvant Agents with Oral Activity against Doxorubicin Cardiotoxicity and Anticancer Efficacy卡维地洛衍生的具有口服活性的双功能佐剂剂的设计与合成：针对多柔比星心脏毒性和抗癌功效
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-27
delete0
PREAI
deleteXinyu Wu; Xianggang Mu; Qian Liu; Yinxu Liu; Shuqing Guo; Maoying Guan; Huimin Shen; Wanxin Hou; Xiangdong Xu; Yushui Ma; Changsheng Dong; Hegen Li; Jian Li; Lijun Jia; Fei Mao; Shuaishuai Ni
delete分享
delete收藏
Silencing las and rhl Quorum Sensing Systems in MDR Pseudomonas aeruginosa: Design, Synthesis, Biological Evaluation and Molecular Modeling of Novel Quinolin-2-one Derivatives沉默MDR铜绿假单胞菌中las和rhl群体感应系统：新型喹啉-2-酮衍生物的设计、合成、生物评价及分子模拟
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-27
delete0
PREAI
deleteMahmoud Alaaeldin Khattab; Mai I. Shahin; Mohamed S. Turkey; Ahmed B.M. Mehany; Nermin Samir; Azza T. Taher
delete分享
delete收藏
Discovery and Pharmacological Profiling of Quinoline- and Quinoxaline-Based Phenoxypropanoic Acid Derivatives as Multitarget Modulators of PPARα, FXR, and LXRα receptors喹啉基和喹喔啉基苯氧基丙酸衍生物的发现及其作为PPARα、FXR和LXRα受体多靶点调节剂的药理学表征
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-27
delete0
deleteOAAI
deleteIuliia Melnikova; Galina Karabanovich; Jan Dušek; Martin Ambrož; Hana Laštůvková; Tomaš Smutný; Mária Bajnoková; Rajamanikkam Kamaraj; Rudy Salam; Adam Reguli; Petra Štěrbová-Kovaříková; Otto Kučera; Stanislav Mičuda; Jaroslav Roh; Petr Pávek
delete分享
delete收藏
Targeting Carbonic Anhydrase IX to Overcome Hypoxia-Driven Resistance in Glioblastoma靶向碳酸酐酶IX以克服缺氧驱动型耐药性在胶质母细胞瘤
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-26
delete0
deleteOAAI
deleteAlessia Onali; Lorenza Guarnieri; Erica Sanna; Francesca Bosco; Antonio Lupia; Daniela Secci; Andrea Angeli; Lisa Sequeira; Rita Meleddu; Filippo Cottiglia; Enrico Podda; Giovambattista De Sarro; Claudiu T. Supuran; Simona Distinto; Elias Maccioni
delete分享
delete收藏
Design, Synthesis and SAR Studies of N’-(Heteroarylsalicylidene)- and N’-(Fused-heterobicyclosalicylidene)-N-arenecarbohydrazides as Next-Generation Broad-Spectrum Antifungal AgentsN’-(杂芳基水杨醛)-和N’-(稠杂双环水杨醛)-N-芳基酰肼的设计、合成及构效关系研究作为下一代广谱抗真菌剂
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-24
delete0
deleteOAAI
deleteAshna Garg; Nathalia Fidelis Vieira de Sa; Ananya Shibana Thennarasu; Kathryn Takemura; Gabriel S. Matos; Jacob Acosta; Neelu Singh; Caroline Correa De Almeida; Nivea Pereira De Sa; Maurizio Del Poeta; Iwao Ojima
delete分享
delete收藏
Cancer-selective cytotoxicity of a semi-synthetic derivative of oleuropein via proteostasis network impairment橄榄苦苷半合成衍生物通过破坏蛋白质稳态网络对癌细胞的选择性细胞毒性
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-24
delete0
deleteOAAI
deleteDespoina D. Gianniou; Christos K. Kontos; Eirini Gkogkou; Georgia Sarikaki; Paraskevi Karousi; Alexios-Leandros Skaltsounis; Andreas Scorilas; Ioannis K. Kostakis; Ioannis P. Trougakos
delete分享
delete收藏
Metal-Organic Frameworks for Cancer Drug Delivery: Molecular Design, Therapeutic Mechanisms, Safety, and Clinical Translation金属有机框架在癌症药物递送中的应用：分子设计、治疗机制、安全性与临床转化
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-23
delete0
PREAI
deleteLama Ahmed Alahmary; Farah Ayman Sukkarieh; Umme Tamanna Ferdous; Aasif Helal; Shihab Uddin
delete分享
delete收藏
H2S-Activated NO-Releasing Theranostics for Combined Gas and Photodynamic Therapy against Colorectal cancerH2S激活的NO释放诊疗剂用于联合气体和光动力疗法对抗结直肠癌
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-23
delete0
PREAI
deleteKehuan Wu; Shaozong Ma; Chenjia Liu; Mengting Zhao; Yongxing Xue; Jiaxin Cheng; Chunchang Zhao; Lixin Sun; Xianfeng Gu
delete分享
delete收藏
Half-Sandwich Ir(III) and Rh(III) Complexes Bearing a π-Extended Pyrene-based NˆN-Ligand: Metal- and Monodentate Ligand Influence on Photodynamic Therapy半夹心式Ir(III)和Rh(III)配合物：基于扩展π-萘并基的NˆN配体及其在光动力疗法中对金属和单齿配体的影响
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-23
delete0
deleteOAAI
deleteCarlos Gonzalo-Navarro; Anna Massaguer; Juan Ángel Organero; Lucía Santos; Joao Carlos Lima; Artur J. Moro; Ana María Rodríguez; Sílvia Barrabés; Mònica Iglesias; Pedro Tavares; Gema Durá; Blanca R. Manzano
delete分享
delete收藏
Artificial Intelligence in Antiviral Drug Discovery: Data Resources, Methods, and Applications人工智能在抗病毒药物发现中的应用：数据资源、方法和应用
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-22
delete0
PREAI
deleteGuoliang You; Jiaqi Li; Junyu Chen; Bingrui Wang; Zhongxin Xu; Jing Wang; Luqing Shang
delete分享
delete收藏
Corrigendum to “ Engineering β-amino acid antimicrobial peptides with enhanced stability and potential efficacy against gram-negative bacterial infections” [Eur. J. Med. Chem. 310 (2026) 118802]勘误：“Engineering β-amino acid antimicrobial peptides with enhanced stability and potential efficacy against gram-negative bacterial infections” [Eur. J. Med. Chem. 310 (2026) 118802]
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-22
delete0
PREAI
deleteJingyi Zhu; Luyang Gao; Wenjing Xue; Jing Zou; Jiahui Wang; Yashi Wang; Yun Zhang; Sanhu Gou; Hui Liu; Chao Zhong; Jingman Ni
delete分享
delete收藏
Design, Synthesis, and Antitumor Evaluation of Novel VEGFR-2/BRD4 Dual Inhibitors with Potent In Vivo Efficacy新型VEGFR-2/BRD4双抑制剂的设计、合成及体内抗肿瘤活性评价
deleteEuropean Journal of Medicinal Chemistry
IF5.9
delete2026-10-22
delete0
PREAI
deleteZhenling Liu; Zexi Cui; Xiaoling Zhang; Ru Wang; Xiangpeng Dai; Lei Shi
delete分享
delete收藏