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Expert Opinion on Drug Discovery 封面图

Expert Opinion on Drug Discovery

IF4.9
论文数2163
被引数6668
期刊论文 2163
发表时间
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Cholinergic-targeted molecular hybrids: a renewed strategy for Alzheimer’s disease?胆碱能靶向分子杂化物：治疗阿尔茨海默病的新策略？
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IF4.9
delete2026-10-29
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deleteMarco Cerini; Rosalba Leuci; Marco Paparella; Vincenzo Roselli; Luca Piemontese
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Targeting fibroimmune remodeling in androgenetic alopecia: emerging opportunities for RNA-based drug discovery靶向雄激素性秃发中的纤维免疫重塑：基于RNA药物发现的崭新机遇
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-10-15
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PREAI
deleteIn Guk Park; Leegu Song; Jayhyun Cho; Minsoo Noh; Jong-Hyuk Sung
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Current applications of isothermal titration calorimetry for lead optimization等温滴定 calorimetry 在先导化合物优化中的当前应用
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IF4.9
delete2026-10-14
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PREAI
deleteHuiyang Hu; Martin Guerrero; Yuping Bao
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From stochastic systems to governed intelligence: a neurosymbolic path for pharma从随机系统到治理智能：制药领域的神经符号路径
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-10-12
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PREAI
deleteShawn Zheng Kai Tan; Joshua Daniel Valdez; Adam Bohr
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Organoids in drug discovery and development: emerging technologies to transition beyond animal models类器官在药物发现和开发中的应用：超越动物模型的涌现技术
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-10-05
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PREAI
deleteJolene Phelps; Amanda Orr; Stephanie M. Willerth
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Using molecular modeling and QSAR-based design strategies for advancing the development of therapeutic solute carrier 6 (SLC6) transporter ligands利用分子建模和基于QSAR的设计策略促进治疗性溶质载体6(SLC6)转运蛋白配体的开发
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-10-04
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PREAI
deleteMartyna Ogos; Marek Bajda
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Lymph node models of chronic lymphocytic leukemia for translational evaluation of new drug candidates慢性淋巴细胞白血病淋巴结模型用于新药物候选物的转化评估
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-09-28
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deleteLucy Clarke; Celia Ribes Balanza; Alison M. Michie; Hannah Donnelly
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Strategy-based design for the identification of next generation β-lactam antibiotics that evade resistance from Gram-negative pathogens基于策略的设计：用于识别能够规避革兰氏阴性病原体耐药性的下一代β-内酰胺类抗生素
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IF4.9
delete2026-09-27
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PREAI
deleteMichio Kurosu; Iván Cheng-Sánchez; Mohammad M. Aboulwafa; Amro Hanora; Mohamed K. El-Ashrey; Ahmad M. Abbas; Mahmoud A. El Hassab; Moustafa A. Tageldein; Francisco Sarabia
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Design considerations for in silico drug discovery platform that can accelerate targeted drug repurposing: a focus on rare, neglected, and emerging diseases面向加速靶向药物重定位的计算机药物发现平台设计考量：聚焦罕见病、被忽视疾病和新发疾病
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IF4.9
delete2026-09-25
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PREAI
deleteAlan Talevi
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The rapid emergence of small molecule RNA modulator hit discovery: unlocking the potential小分子RNA调节剂命中发现的快速涌现：解锁潜力
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IF4.9
delete2026-09-22
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deleteRachel Moore; Alessandro Bonetti; Rhona J. Cox; Stefan Geschwindner; Mariacarmela Giurrandino; Sergio Martinez Cuesta; Stefan Schiesser
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Epidermal growth factor receptor (EGFR)-directed PROTACs: mechanistic validation, mutant selectivity, and translational challenges表皮生长因子受体（EGFR）靶向PROTACs：机制验证、突变选择性及转化挑战
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IF4.9
delete2026-09-20
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deleteYash Hegde; Ranjit K. Mehta; Mingjia Tan; Theodore S. Lawrence; Alexander J. Bridges; Mukesh K. Nyati
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Incentivizing challenging drug discovery: from reducing failure to quantifying uncertainty激励具有挑战性的药物发现：从减少失败到量化不确定性
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-09-17
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deleteStefano Moro
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Tumor spheroids versus organoids: defining the more suitable three-dimensional model for cancer research肿瘤球体与类器官：为癌症研究定义更适宜的三维模型
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IF4.9
delete2026-09-04
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PREAI
deleteHiral Tanna; Shrey Shah
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Advances in the emerging field of epi-informatics in drug discovery: roads taken and future prospects药物发现中新兴表观信息学领域的进展：已走之路与未来展望
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-09-02
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deleteAylin Del Moral-Morales; Erik D. Díaz-Dionisio; José L. Medina-Franco
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Limitations of current drug hybridization strategies and the challenges ahead当前药物杂化策略的局限性与未来挑战
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-09-01
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deleteJoana Gil; Tânia S. Morais
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Challenges in modeling interstitial cystitis: implications for drug discovery efforts间质性膀胱炎建模的挑战：对药物发现工作的启示
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IF4.9
delete2026-08-31
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deleteJohn A. Arnott; Sonia Lobo
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Bioengineered In vitro bone marrow models of acute myeloid leukemia for novel drug discovery生物工程体外骨髓模型在急性髓系白血病新药发现中的应用
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-08-30
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deleteCelia Ribes-Balanza; Lucy Clarke; Matthew J. Dalby; Hannah Donnelly
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Opportunities in drug discovery innovation and the vital role of preclinical research药物发现创新的机会及临床前研究的至关重要性
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IF4.9
delete2026-08-29
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deleteWerngard Czechtizky
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Fatty acid amide hydrolase (FAAH) inhibitor design and preclinical studies: lessons learned from BIA 10–2474 and the challenges ahead脂肪酸酰胺水解酶（FAAH）抑制剂的设计与临床前研究：从BIA 10–2474中吸取的教训及面临的挑战
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-08-19
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deleteAlessia Catalano; Filomena Fezza; Andrea Duranti; Maria Maddalena Cavalluzzi; Giovanni Lentini; Giuseppe Felice Mangiatordi; Marco Bruno Luigi Rocchi; Mauro Maccarrone
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Models of depression for preclinical drug discovery and development: an update of the literature抑郁症模型用于临床前药物发现与开发：文献更新
deleteExpert Opinion on Drug Discovery
IF4.9
delete2026-08-19
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deletePavlina Pavlidi; Dimitrios Kalampokis; Ifigeneia Ioannidi; Kalliopi Skourti; Ioannis Sotiropoulos; Katerina Antoniou; Christina Dalla; Nikolaos Kokras
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