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Biochemical Pharmacology 封面图

Biochemical Pharmacology

IF5.6
论文数13412
被引数32983
期刊论文 13412
发表时间
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TMEM63B as a dual-function mechanosensitive channel and lipid scramblase: structural insights, physiological roles, and pharmacological potentialTMEM63B作为双重功能机械敏感性通道和脂质 scrambling酶：结构见解、生理作用和药理潜力
deleteBiochemical Pharmacology
IF5.6
delete2026-10-29
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PREAI
deleteZihan Chang; Zhirong Wang; Jiayi Tong; Yakun Yu; Jieyu Qi; Renjie Chai; Yanfeng Wang
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Gramine limits alcohol-associated liver injury by suppressing NOX1-linked ferroptotic responses and mitochondrial dysfunction石蒜碱通过抑制NOX1相关的铁死亡反应和线粒体功能障碍来限制酒精相关性肝损伤
deleteBiochemical Pharmacology
IF5.6
delete2026-10-28
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PREAI
deleteYu Zhang; Luxia Su; Heran Cheng; Wei Wei; Wenxuan Xu; Xiaofeng Bao; Chunfeng Lu
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Withaferin A induces apoptosis and ferroptosis in gastric cancer cells via ROS-mediated mitochondrial damage and the Keap1/Nrf2/HO-1/GPX4 axis威斯塔非林A通过ROS介导的线粒体损伤和Keap1/Nrf2/HO-1/GPX4轴诱导胃癌细胞发生凋亡和铁死亡
deleteBiochemical Pharmacology
IF5.6
delete2026-10-28
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PREAI
deleteYangbo Liu; Yanjun Tang; Dongzhao Xie; Qianqian Zhang; Zhuang Hu; Linyue Bai; Siqi Feng
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D14, a β-carboline alkaloid derivative of dehydrocrenatidine, exerts anti-glioma effect by targeting SRCD14，一种源自去氢川芎嗪的β-咔啉生物碱衍生物，通过靶向SRC发挥抗胶质瘤作用
deleteBiochemical Pharmacology
IF5.6
delete2026-10-28
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PREAI
deleteYu-Jue Wang; Shu-Yan Qin; Yan-Jun Ji; Ze-Yang Li; Shao-Di Wu; Guo-Duan Liang; Jia-Yi Zhang; Xiao-Xiao Huang; Yong-Xiang Liu; Bin Lin; Shao-Jiang Song; Guo-Dong Yao
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cGAS-STING activation promotes abdominal aortic aneurysm formation in mice and humans: Therapeutic potential of inhibitioncGAS-STING活化促进小鼠和人类腹主动脉瘤形成：抑制的潜在治疗价值
deleteBiochemical Pharmacology
IF5.6
delete2026-10-28
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PREAI
deletePengcheng Du; Xiaochen Ma; Feixiang Zhu; Guanglang Zhu; Fei Li; Han Nie; Min Yu; Li Tang; Junyi Yan; Yongqiang Li; Yudong Sun; Kai Huang; Hui Yang; Jiaxuan Feng
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Mechanisms of cetuximab resistance in head and neck squamous cell Carcinoma: Focus on the EGFR–ERK pathway头颈部鳞状细胞癌中西妥昔单抗耐药的机制：聚焦于EGFR–ERK通路
deleteBiochemical Pharmacology
IF5.6
delete2026-10-27
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PREAI
deleteLiliya Galiyeva; Josipa Grušanović; Jiří Netušil; Vojtěch Melichar; Zuzana Klímová; Michal Kolář; Jan Plzák; Jana Šachová; David Kalfeřt; Tomáš Vomastek
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Role and mechanism of action of PINK1/Parkin-mediated mitophagy in nonylphenol-induced podocyte apoptosis and glomerulonephritisPINK1/Parkin介导的线粒体自噬在壬基酚诱导的足细胞凋亡和肾小球肾炎中的作用及机制
deleteBiochemical Pharmacology
IF5.6
delete2026-10-27
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PREAI
deleteChengxing Wang; Jie Xu; Yuzhu Xu; Ya Luo; Jie Yu
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Corrigendum to “Trillin alleviates rheumatoid arthritis by inhibiting TXNIP-mediated mitochondrial damage and NLRP3-dependent pyroptosis” [Biochem. Pharmacol. 254 (2026) 118489]勘误：“Trillin通过抑制TXNIP介导的线粒体损伤和NLRP3依赖性焦亡来缓解类风湿性关节炎”[Biochem. Pharmacol. 254 (2026) 118489]
deleteBiochemical Pharmacology
IF5.6
delete2026-10-26
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PREAI
deleteJingjing He; Xinying Wang; Xiaodi Lian; Yuyan She; Wenhao Xu; Xiaoyan Sun; Yan Li; Peng Cao; Chenglei Zhao
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Glycosylated steroidal saponins suppress HNSCC progression by targeting the RAS–ERK pathway糖基化甾体皂苷通过靶向RAS–ERK通路抑制HNSCC进展
deleteBiochemical Pharmacology
IF5.6
delete2026-10-26
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PREAI
deleteWenming Jia; Shuai Chen; Ye Qian; Zheyong Xue; Heng Liu
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The PHLPP paradox revisited: from canonical AKT phosphatases to signaling pseudoenzymes in human diseasePHLPP悖论的再探讨：从经典AKT磷酸酶到人类疾病中的信号伪酶
deleteBiochemical Pharmacology
IF5.6
delete2026-10-25
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PREAI
deleteEsraa M. Shaaban; Moemena F. Elnaggar; Asmaa Abdelgawad; Mohamed Sedeek; Shady Estfanous; Omar Eladl
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Biochemistry of protozoan Metacaspases: Structure, processing, and inhibition原生动物半胱氨酸蛋白酶的生化特性：结构、加工与抑制
deleteBiochemical Pharmacology
IF5.6
delete2026-10-24
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deleteVinicius H. de Oliveira; Ane C.M. Duarte; Aline F. Araujo; Ramon C.M. Candido; Laura M.C. de Lorena; Maurício F.M. Machado
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Artesunate targets STAT3 to alleviate Hodgkin’s lymphoma via JAK-STAT/PD-L1 axis青蒿琥酯通过JAK-STAT/PD-L1轴靶向STAT3以缓解霍奇金淋巴瘤
deleteBiochemical Pharmacology
IF5.6
delete2026-10-24
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PREAI
deleteDi Chen; Geng Zhang; Jinghui San; Baoru Liu; Ping Yuan; Mingqiang Ren
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Mots-c attenuates diabetic nephropathy by downregulating LARS1 to promote lipophagy and suppress tubular senescenceMots-c通过下调LARS1来促进脂质自噬并抑制肾小管衰老，从而减轻糖尿病肾病
deleteBiochemical Pharmacology
IF5.6
delete2026-10-23
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PREAI
deleteJiayi Wang; Shilu Luo; Yachun Han; Li Li; Ling Wei; Wei Chen; Ming Yang
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Targeting coagulation factor XI/XIa for anticoagulation therapy: from mechanism to drug development靶向凝血因子XI/XIa的抗凝治疗：从机制到药物开发
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IF5.6
delete2026-10-23
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PREAI
deleteYang Zhou; Mingdong Huang; Peng Xu; Haili Lin
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HSP27, cell stress, and hormesis: From mammals to humanized yeast modelsHSP27、细胞应激与 hormesis：从哺乳动物到人源化酵母模型
deleteBiochemical Pharmacology
IF5.6
delete2026-10-23
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PREAI
deleteVittoria de Lima Camandona; Gabriela Maria Redondo da Silva; Esther Dantas Batista; Eduardo Vieira Vilaronga; Jose Ribamar Ferreira-Junior
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Revealing NMN-induced biomacromolecular complex and conformational regulation of digestive enzymes (Trypsin, Pepsin, α-Amylase): Insights from molecular dynamics simulation and multi-spectroscopy揭示NMN诱导的消化酶（胰蛋白酶、胃蛋白酶、α-淀粉酶）生物大分子复合物及构象调控：分子动力学模拟和多光谱分析研究
deleteBiochemical Pharmacology
IF5.6
delete2026-10-23
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PREAI
deleteWenhua Tong; Juan Dai; Xingyan Liu; Dunhui Jiang; Jie Yang; Ying Yang
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Ethanol metabolism and acetaldehyde clearance: A multi-organ symphony乙醇代谢与乙醛清除：多器官协同作用
deleteBiochemical Pharmacology
IF5.6
delete2026-10-23
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PREAI
deleteCheng Chen
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ZYX knockdown alleviates chemotherapy resistance in epithelial ovarian cancerZYX敲低缓解上皮性卵巢癌的化疗耐药性
deleteBiochemical Pharmacology
IF5.6
delete2026-10-23
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PREAI
deleteXiangyun Hu; Shijiao Wang; Ruihui Yang; Xiaoting Zhang; Yaoyao He; Changtao Zheng; Ying Ding; Huainian Zhang; Ali Chen; Yongxia Yang; Yongli Zhang
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The ATG4 family: Molecular gatekeepers of autophagic flux and emerging targets for disease intervention自噬相关基因4家族：自噬通量的分子守门人及新兴疾病干预靶点
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IF5.6
delete2026-10-23
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PREAI
deleteDan Mu; Xiong Pei; Jiajie Feng; Xinzhu Dong; Xuemei Qiu; Wenke Jin; Dongbo Wu; Lan Zhang
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Thymoquinone exerts anti-inflammatory effects in multiple disease models by regulating immune-inflammatory homeostasis噻吩醌通过调控免疫-炎症稳态在多种疾病模型中发挥抗炎作用
deleteBiochemical Pharmacology
IF5.6
delete2026-10-23
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PREAI
deleteSen Wang; Han Wang; Yuan Zhao; Yifei Liu; Yanhong Zhou; Ni Zhu
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