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Frontiers in Drug Discovery

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论文数25
被引数
期刊论文 25
发表时间
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Effectiveness of ozonized oil-based ear drops in patients with external ear canal dermatitis: a prospective observational study臭氧化油基滴耳液对外耳道皮炎患者的疗效：一项前瞻性观察研究
deleteFrontiers in Drug Discovery
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delete2026-05-18
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PREAI
deleteDi Giovanni, Simone; Sabatino, Lorenzo; Iafrati, Francesco; Pericone, Giovanni Rocco Maria; Petruzzellis, Alessandra; De Benedetto, Luigi; Moffa, Antonio; Casale, Manuele
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Virtual screening and molecular dynamics simulations of cannabinoid receptor 2 agonists as drug candidates for osteoarthritis therapy虚拟筛选和分子动力学模拟：将大麻素受体2激动剂作为骨关节炎疗法的药物候选物
deleteFrontiers in Drug Discovery
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delete2026-05-15
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deleteDe Souza, Fernanda F.; Vilacha, Juliana F.; De Paula, Heberth; Honorio, Kathia Maria
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Sequence-dominant protein therapeutics: mechanistic foundations for efficient biologics development序列主导型蛋白质治疗剂：高效生物药开发的机制基础
deleteFrontiers in Drug Discovery
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delete2026-05-11
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deleteNiazi, Sarfaraz K.
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Artificial intelligence for small-molecule chemical probe design: why drug-centric models may not transfer cleanly人工智能在小分子化学探针设计中的应用：以药物为中心的模型为何可能无法实现干净的迁移
deleteFrontiers in Drug Discovery
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delete2026-05-04
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deleteCarlucci, Renzo; Porta, Exequiel O. J.
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From biosimilars to breakthroughs: regulatory convergence toward evidence-efficient development of monoclonal antibodies从生物类似药到突破性进展：单克隆抗体证据高效开发的监管趋同
deleteFrontiers in Drug Discovery
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delete2026-04-30
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deleteNiazi, Sarfaraz K.
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Phα1β cardiovascular safety pharmacology using the telemetry system in rats使用遥测系统进行的大鼠Phα1β心血管安全性药理学研究
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delete2026-04-30
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deleteCastro Junior, Celio Jose; Gomez, Marcus Vinicius
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Bispecific and trispecific antibodies in atopic dermatitis: a review of the emerging clinical pipeline双特异性及三特异性抗体在特应性皮炎中的应用：新兴临床管线的综述
deleteFrontiers in Drug Discovery
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delete2026-04-15
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deleteAmid-Toby, Gili; Alani, Omar; Bunick, Christopher G.
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Optimization of a malachite green-pyrophosphatase assay for the Zika virus RNA-dependent RNA polymerase and preliminary identification of natural product modulators针对寨卡病毒RNA依赖性RNA聚合酶的孔雀石绿-焦磷酸酶测定优化及天然产物调节剂的初步鉴定
deleteFrontiers in Drug Discovery
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delete2026-04-14
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deleteAitken, Vanessa; Moore, Anthony F. T.; Terrazas-Lopez, Manuel; Rodarte, Salvador; Koculi, Eda
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Neuro-regulatory drug discovery (NRGDD): a neural-circuit framework for systemic therapeutic modulation神经调节药物发现（NRGDD）：一种系统性治疗调节的神经回路框架
deleteFrontiers in Drug Discovery
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delete2026-04-13
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deleteNiazi, Sarfaraz K.
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Beyond GLP-1: underexplored peptide-receptor systems as the next frontier in drug discovery超越GLP-1：未充分开发的肽-受体系统作为药物发现的下一个前沿
deleteFrontiers in Drug Discovery
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delete2026-04-10
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deleteNiazi, Sarfaraz K.
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Multivalent display of membrane proteins using HIV-1 Gag VLPs利用HIV-1 Gag病毒样颗粒展示多价膜蛋白
deleteFrontiers in Drug Discovery
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delete2026-03-05
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deleteBhat, Neha A.; Dunn, Nicholas; Yu, Xiaodi; Duprie, Matthew; Dutta, Supratik; McLean, Matthew; Feldkamp, Micheal D.; Kratch, Jacqueline; Mann, Mandeep K.; Rahighi, Simin; Davidson, Robert C.; Leppard, John B.; Cheung, Wan Cheung; Khandelwal, Puneet
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Across preclinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions在预临床和临床平台中，已批准和正在研究的抗精神病药物共享通路并与相似的分子功能相关联
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delete2026-03-04
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deleteSu, Emily; Valencia, Nico Matthew S.; Le, Jarod; Liu, Emily; Wilson, Jennifer L.
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Revisiting the grand challenges: the road travelled and ahead at the frontiers of computer-aided drug design重新审视重大挑战：计算机辅助药物设计前沿的已行之路与未来之路
deleteFrontiers in Drug Discovery
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delete2026-02-16
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deleteMedina-Franco, Jose L.
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Standardization of canine infections for the development of antileishmanial drugs犬感染标准化以开发抗利什曼药物
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delete2026-02-11
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deleteOlias-Molero, A. I.; Corral-Caridad, M. J.; Jimenez-Anton, M. D.; Mateo-Barrientos, M.; Carrion, J.; Torrado, J. J.; Alunda, J. M.
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Structure-based virtual screening for TRPM8 modulators基于结构的TRPM8调节剂虚拟筛选
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delete2026-01-28
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deleteJames, Nivya; Ballester, Pedro J.
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Enhancing structure-based virtual screening of MDM2-p53 inhibitors: a benchmark of machine learning vs. traditional docking scoring functions基于结构的MDM2-p53抑制剂虚拟筛选的增强：机器学习与传统对接评分函数的基准比较
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delete2026-01-16
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deleteCastillo Tarazona, Marcia Yineth; Miscione, Gian Pietro
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Dual RNA polymerase I inhibition with CX-5461 and BMH-21 synergizes in breast cancer by activating p53-dependent stressCX-5461和BMH-21联合抑制双RNA聚合酶I在乳腺癌中通过激活p53依赖性应激产生协同作用
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delete2026-01-05
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deleteChung, Jonathan Y.; Nguyen, Kristen N.; Knutson, Bruce A.
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Grand challenges in dermatologic drug discovery: four priorities to transform skin disease treatment皮肤科药物发现中的重大挑战：转变皮肤病治疗的四大优先事项
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delete2026-01-05
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deleteGrada, Ayman
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A network-based protocol to prioritize compounds for biological testing: discovery of Anti-Staphylococcus aureus cacalol derivatives基于网络的协议用于优先选择生物测试化合物的策略：抗金黄色葡萄球菌 cacalol 衍生物的发现
deleteFrontiers in Drug Discovery
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delete2025-12-10
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deleteLopez-Lopez, Edgar; Pardo-Novoa, Julio C.; Barrientos-Salcedo, Carolina; Vichi-Ramirez, Micheel M.; Cerda-Garcia-Rojas, Carlos M.
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Exploring deep learning approaches in anticancer drug design: a review of recent advances探索抗肿瘤药物设计中的深度学习方法：近期进展综述
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delete2025-12-10
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deleteM'rhar, Kaoutar; Chadi, Mohamed-Amine; Mousannif, Hajar
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