logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回期刊详情
L

LETTERS IN DRUG DESIGN & DISCOVERY

IF1.6
论文数59
被引数
期刊论文 59
发表时间
delete
Exploring coumarin derivatives as promising Acetylcholinesterase inhibitors in alzheimer disease: Integrating QSAR, docking, MD simulations, and DFT study探索香豆素衍生物作为阿尔茨海默病中具有潜力的乙酰胆碱酯酶抑制剂的可行性：整合定量构效关系、分子对接、分子动力学模拟和密度泛函理论研究
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-04-01
delete0
PREAI
deleteSaini, Sweety; Paliwal, Deepika; Thakur, Aman
delete分享
delete收藏
Artificial intelligence and machine learning in drug discovery: From lead discovery to clinical validation (2020-2025)人工智能和机器学习在药物发现中的应用：从先导化合物发现到临床验证（2020–2025）
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete5
PREAI
deleteVerma, Vikrant; Kumar, Dharmendra
delete分享
delete收藏
Integrating single-cell sequencing and network pharmacology to reveal the mechanisms of matrine against ulcerative colitis整合单细胞测序和网络药理学以揭示苦参碱治疗溃疡性结肠炎的作用机制
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteLin, Minghua; Lan, Luying; Li, Fudi; Ye, Wen; Huang, Qijian
delete分享
delete收藏
Investigation of 4-(4-Chlorophenyl)-2,4-dihydro-5-(4-pyridyl)-3H-1,2,4-triazole-3-thione in morphine induced dependence model augmented by simulation and molecular docking4-(4-氯苯基)-2,4-二氢-5-(4-吡啶基)-3H-1,2,4-三唑-3-硫酮在模拟增强的吗啡诱导依赖模型中的研究
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteAyub, Insha; Qazi, Neelum Gul; Badshah, Ismail; Nadeem, Humaira; Hussain, Sajid; Ullah, Farman; Alsharif, Khalaf F.; Alzahrani, Khalid J.; Ali, Fawad; Khan, Haroon
delete分享
delete收藏
Integration of single-cell sequencing and multi-omics approaches with pharmacological analysis to unveil biomarkers and mechanisms of traditional Chinese medicine in treating heart diseases整合单细胞测序与多组学方法及药理学分析以揭示中医药治疗心脏病的生物标志物和作用机制
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteWang, Xiancheng; Wang, Lu; Su, Hongyan; Yuan, Na; Wang, Te
delete分享
delete收藏
Exploring the mechanism of Squamocin inhibits oral squamous cell carcinoma malignant progression by targeting peroxisome proliferator activated receptor-gamma based on network pharmacology and molecular docking基于网络药理学和分子对接探究Squamocin通过靶向过氧化物增殖物激活受体-γ抑制口腔鳞状细胞癌恶性进展的机制
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteHu, Daoyong; Dai, Qun; Xiong, Hao; Zhong, Tian
delete分享
delete收藏
Urolithin D sensitizes hepatocellular carcinoma to T-cell responses through downregulating ACOT7/PD-L1 axis尿石素D通过下调ACOT7/PD-L1轴来增强肝细胞癌对T细胞反应的敏感性
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteLi, Xiaolou; Luo, Qiong; Chen, Ying; Wei, Guangmin; Zhang, Lina
delete分享
delete收藏
Integrative single-cell sequencing and metabolomics reveal the immunometabolic regulatory network of alirocumab in atherosclerosis: Focus on the PCSK9-LOX-1-NF-κB-IL-6 axis and therapeutic prospects整合单细胞测序和代谢组学揭示alirocumab在动脉粥样硬化中的免疫代谢调控网络：聚焦于PCSK9-LOX-1-NF-κB-IL-6轴及治疗前景
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteWang, Yi-Sheng; Wang, Xue; Chen, Min; Lu, Ping; Qian, Zhuo-Lei
delete分享
delete收藏
Indolizines in focus: Synthetic approaches, biological profiles, and SAR perspectives, a review吲哚嗪类化合物研究进展：合成方法、生物活性和构效关系，综述
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deletePathak, Shilpi; Sharma, Vishnu; Agrawal, Neetu
delete分享
delete收藏
Eco-friendly synthesis of CUO-Ag nanoparticles using Mentha Longifolia and their anticancer efficacy in breast and gastric cancer cells利用薄荷长叶提取液制备氧化亚铜-银纳米粒子的绿色合成及其在乳腺癌和胃癌细胞中的抗癌活性
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deletePahlevanhosseini, Hoda; Khorin, Fatemeh Siahmansuor; Mohammadgholi, Azadeh; Moghaddam, Nastaran Asghari
delete分享
delete收藏
Indole ring linked thiazolidone hybrid molecules as potent tubulin inhibitors吲哚环连接的噻唑烷酮杂化分子作为强效微管蛋白抑制剂
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteAbba, Abdulrahman; Unal, Naz; Dede, Zulal Sevgi; Bedir, Ipek; Telci, Dilek; Aru, Basak; Demirel, Gulderen Yanikkaya; Akdeniz, Gunes Yildirim; Timucin, Ahmet Can; Gungor, Burcin; Akgun, Hulya
delete分享
delete收藏
Computational design and screening of novel dipeptide analogues as potent antileprotic agents against alanine racemase and ligase新型二肽类似物的计算设计与筛选：作为针对丙氨酸消旋酶和连接酶的强效抗麻风病药物
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteSharma, Richa; Sharma, Riya; Nagarajan, Kandasamy; Bhardwaj, Snigdha; Tripathi, Arun Kumar; Shrivastava, Ajay Kumar; Kumar, Nikhil; Verma, Ankit; Goel, Richa
delete分享
delete收藏
From quantum chemistry to dynamics: Computational insights into Petrosin as a promising antidiabetic α-amylase inhibitor
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteBou-Salah, Leila; Linani, Abderahmane; Khalipha, Abul Bashar Ripon; Benarous, Khedidja; Kaouka, Alaeddine; Al Hasan, Md Sakib
delete分享
delete收藏
Automated detection of breast cancer using machine learning and deep learning models from tabular data基于表格数据的机器学习和深度学习模型自动检测乳腺癌
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteJaved, Hina; Abdullah; Saeed, Ali; ul Haque, Hafiz Mahfooz; Fatima, Zulaikha; Rodriguez, Jose Luis Oropeza; Sanchez-Mejorada, Carlos Guzman
delete分享
delete收藏
Mechanistic analysis of oral liquid in the treatment of asthma based on network pharmacology and machine learning基于网络药理学和机器学习的口服液体在哮喘治疗中的机制分析
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-03-01
delete0
PREAI
deleteRen, Yumei; Li, Zixi; Bai, Han; Li, Le; Jing, Xiaojin
delete分享
delete收藏
Investigation of the therapeutic targets of BanXia on astrocytes and neurons in stroke based on transcriptomics and network pharmacology基于转录组学和网络药理学探讨半夏对卒中星形胶质细胞和神经元的治疗靶点
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-02-01
delete0
PREAI
deleteLiu, Xiaohu; Hua, Hua; Liu, Jing; Wang, Pei; Li, Peng; Song, Huifang; Hussain, Rabia
delete分享
delete收藏
Advances in stem cell therapy, nanomedicine, multi-omics, and artificial intelligence-assisted strategies for the treatment of lung injury and pulmonary fibrosis干细胞疗法、纳米医学、多组学和人工智能辅助策略在肺损伤和肺纤维化治疗中的进展
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-02-01
delete0
deleteOAAI
deleteSong, Dingyun; Yang, Yi; Li, Zhongwen; Song, Licheng; An, Bin; Yuan, Zheming; Liu, Yaru; Su, Ruofan; Guo, Wenjing; Xie, Lixin
delete分享
delete收藏
Benzimidazole derivatives as kinase inhibitors: Synthetic strategies, and therapeutic prospects in cancer苯并咪唑衍生物作为激酶抑制剂：合成策略及在癌症中的治疗前景
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-02-01
delete0
PREAI
deleteChauhan, Suman Birbal; More, Uttam A.; Noolvi, Malleshappa N.
delete分享
delete收藏
A comprehensive review: deep learning-powered revolution in antitumor drug research-exploring multimodal data integration and ethical governance framework综述：深度学习赋能的抗肿瘤药物研究革命——探索多模态数据整合与伦理治理框架
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-02-01
delete1
deleteOAAI
deleteDong, Lei; Fang, Lingzhi; Peng, Wennuan; Yang, Xue
delete分享
delete收藏
Appraisal of antioxidant scavenging and antibiofilm capacities of pyrazolic, isoxazolic-based chalcones and aurones: Synthesis, molecular docking, simulation, and ADME properties吡唑基、异噁唑基查尔酮和 aurones 的抗氧化清除能力和抗生物膜能力的评估：合成、分子对接、模拟和 ADME 特性
deleteLETTERS IN DRUG DESIGN & DISCOVERY
IF1.6
delete2026-02-01
delete0
deleteOAAI
deleteIrshad, Misbah; Ahmed, Mahmood; Aslam, Ali Abbas; Al Mughram, Mohammed H.; Khushi, Mehwish; Tajammal, Affifa; Irfan, Masooma; Muddassar, Muhammad
delete分享
delete收藏