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Genes & Diseases

IF9.4
论文数439
被引数
期刊论文 439
发表时间
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The discovery and evolution of circRNA-encoded peptides: From historical insights to molecular mechanisms and novel therapeutic paradigms环状RNA编码肽的发现与演变：从历史见解到分子机制及新型治疗范式
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IF9.4
delete2026-10-29
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deleteRui Wang; Lin Ye; Peiyan Wang; Mengyang Li; Jianxun Wang
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Genetic architecture of chronic kidney disease: Polygenic susceptibility, developmental programming, and epigenetic inheritance慢性肾脏病的遗传结构：多基因易感性、发育编程和表观遗传继承
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IF9.4
delete2026-10-28
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deleteHongtu Hu; Yinghui Huang
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Predicting bronchopulmonary dysplasia in infants with ARDS using explainable machine learning models使用可解释机器学习模型预测ARDS婴儿的支气管肺发育不良
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IF9.4
delete2026-10-27
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deleteChunyi Wang; Kaizhen Liu; Run Yang; Peihui Li; Xiangyong Tan; Ziyu Hua
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KPNB1 protects SIX2 from TRIM27-dependent ubiquitination and degradation to facilitate clear cell renal cell carcinomaKPNB1通过保护SIX2免受TRIM27依赖性泛素化及降解，以促进肾透明细胞癌的发展
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IF9.4
delete2026-10-27
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deleteHua Zhu; Yue Du; Dayu Tian; Chenyang Zou; Jie Shi; Tao Song; Qianyin Li
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Chemokine-driven angiogenesis and inflammation in diabetic wounds: Mechanistic insights and therapeutic strategies趋化因子驱动的血管生成和炎症在糖尿病伤口中的作用：机制洞察和治疗策略
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IF9.4
delete2026-10-27
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deleteLele Liu; Xiuying Guo; Yuhe Dai; Qianbo Zhang; Junqi Yang; Rifang Gu; Ming Tang; Min Tan; Xuqiang Nie
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The malignant triangle that targets tumors: An interactive network of copper homeostasis, mitochondrial homeostasis, and epigenetic modification靶向肿瘤的恶性三角：铜稳态、线粒体稳态和表观遗传修饰的交互网络
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IF9.4
delete2026-10-24
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deleteJiawen Zhou; Ziyang Yuan; Qi Wang; Miao Zhao; Fei Tang; Zhe Sun; Qianqian Shi; Lei Wu; Ao Zhang; Shu Li; Jun Lu; Zhongwei Li
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Targeting ANGPTL8 as a novel strategy to alleviate glomerular podocyte injury in diabetic nephropathy靶向ANGPTL8作为减轻糖尿病肾病肾小球足细胞损伤的新策略
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IF9.4
delete2026-10-24
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deleteJinxuan Chen; KaiKai Lu; Zihao Zhou; Yanhui Li; Changyun Liu; Yufei Han; Yuan Fang; Chao Zhai; Yitong Xu; Lianxin Zhang; Qiang Shen; Ling Zhang; Yuhui Wang; Yanwen Qin; Wei Huang; Xunde Xian
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Rapid in vivo functional assessment of hearing loss genes by CRISPR-Cas9通过CRISPR-Cas9快速进行听力损失基因的体内功能评估
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IF9.4
delete2026-10-24
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deleteChin-Ju Hu; Aaden H. Fantom; Yaqiao Li; Kevin T.A. Booth
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Circulating tumor DNA-based stratification of the tumor microenvironment for predicting prognosis and targeted therapy response in colorectal cancer基于循环肿瘤DNA的肿瘤微环境分层以预测结直肠癌的预后和靶向治疗反应
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IF9.4
delete2026-10-24
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deleteHaosheng Li; Limin Hu; Xinyuan Cui; Xi Cheng; Teng Xu; Haoran Feng; Feng Ye; Yimei Jiang; Zijia Song; Xiaoqian Jing; Yaqi Zhang; Haiyan Huang; Shaodong Wang; Shuiyu Xu; Lianghui Xu; Zilong Chen; Tao Zhang; Ren Zhao; Xiaopin Ji
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AI-driven multi-omics integration uncovers MYL9+ myofibroblasts as regulators in cancer via TGF-β/Smad7 signalingAI驱动的多组学整合揭示MYL9+肌成纤维细胞通过TGF-β/Smad7信号通路在癌症中发挥调控作用
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IF9.4
delete2026-10-24
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deleteLexin Wang; Jungang Zhao; Ziyang Liu; Huiyan Luo; Xiufang Luo; Xinglan Wang; Ke Xu; Yichun Zheng; Peng Wang
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The FOXO3A/β-Catenin pathway mediates the inhibitory effect of GSS on ferroptosis in lung cancer cellsFOXO3A/β-连环蛋白通路介导GSS对肺癌细胞中铁死亡抑制效应
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IF9.4
delete2026-10-23
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deleteFutao Meng; Jingyi Ding; Wenyi Jin; Fang Yang; Xiangyu Zhai; Xin Zhang; Kaiting Ye; Zhijia Xia
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CRISPR screens reveal synthetic lethal genes and network in chemotherapy-resistant osteosarcomaCRISPR筛选揭示化疗耐药骨肉瘤中的合成致死基因和网络
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IF9.4
delete2026-10-22
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deleteShan Tang; Yirui Huang; Lingling Wang; Birkan Gökbağ; Shuai Shao; Lei Wang; Shangjia Li; Lijun Cheng; Jeffrey D. Parvin; Ryan D. Roberts; Lang Li
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Reciprocal c-Abl–Wnt signaling drives pro-inflammatory reprogramming of tubular epithelial cells and renal fibrogenesis in micec-Abl–Wnt信号通路互作驱动小鼠肾小管上皮细胞的促炎性重编程和肾纤维化
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IF9.4
delete2026-10-20
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deleteQianyi Bao; Anyu Wang; Wenxuan Hong; Xiaodong Yuan; Yushu Wang; Baojie Li; Lin He; Gang Ma
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RPL14 lysine lactylation orchestrates microglial inflammation and neuronal injury following ischemic strokeRPL14赖氨酸乳酰化调控缺血性卒中后小胶质细胞炎症和神经元损伤
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IF9.4
delete2026-10-20
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deleteHengri Cong; Chengcheng Zhao; Miao Li; Jianqiao Li; Hanlin Chen; Mingxuan Huang; Jinghan Guo; Yue Yu; Yujia Shen; Pei Wu; Yiming Deng
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Unravelling the role and functions of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) in Parkinson’s disease pathogenesis and therapeutics解析泛素羧基末端水解酶L1（UCHL1）在帕金森病发病机制和治疗中的作用与功能
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IF9.4
delete2026-10-20
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deleteBalachandar Vellingiri; Kiruthika Balasubramani; Panimalar Abirami Karuppusamy; Deenathayalan Uvarajan; Nandhitha Sri Muneeshwaran; Vikas Lakhanpal; Sindduja Muthukumar; Ajay Elangovan; Harysh Winster Suresh Babu; Mukesh Kumar Yadav; Dibbanti HariKrishnaReddy; Arul Narayanasamy; Mahalaxmi Iyer; Masako Kinoshita
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Cardiovascular and pulmonary adverse events associated with BCMA-directed chimeric antigen receptor T-cell therapyBCMA靶向嵌合抗原受体T细胞治疗相关的心血管和肺部不良事件
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IF9.4
delete2026-10-17
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deleteZhiqiang Song; Zhendong Fu; Yuyan Chen; Dongliang Zhang; Yuke Geng; Jie Wang; Na Liu; Gusheng Tang; Jianmin Yang
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Dissecting shared genetic architecture between metabolic dysfunction-associated steatotic liver disease and extrahepatic diseases解析代谢功能障碍相关脂肪性肝病与肝外疾病之间的共享遗传结构
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IF9.4
delete2026-10-17
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deleteShifang Li; LiLi Lu; Meijiao Gong
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Choroid plexus pathophysiology and artificial intelligence in hydrocephalus: Toward mechanism-informed diagnosis and therapy脉络丛病理生理学与人工智能在脑积水中的应用：迈向机制导向的诊断与治疗
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IF9.4
delete2026-10-17
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deleteCheng Zheng; Bingxuan Ren; Jiawei Wang; Qian Guo; Zuorun Xie; Shiwei Li; Dong Ye; Hongcai Wang; Wu Zheng
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NFKB1 nuclear translocation induced by KPNA2 enhances CXCL10-mediated immune suppression in ovarian cancerKPNA2诱导的NFKB1核转位增强了卵巢癌中CXCL10介导的免疫抑制
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IF9.4
delete2026-10-17
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deleteShijie Xu; Lan Zhang; Shuting Huang; Linjing Yuan; Haifeng Gu; Baoyue Pan; Senwei Jiang; Yinan Jiang; Huiling Xiang; Siyu Chen; Jiaxin Yin; Yajie Sun; Weihua Jia; Xingjuan Yu; Rongzhen Luo; Lili Liu; Jundong Li; Min Zheng
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Integrated multi-omics analysis and experimental validation reveal RFTN1 suppresses M1 polarization via the ANXA5–PKM2 axis in hypertriglyceridemia-associated acute pancreatitis整合多组学分析与实验验证揭示RFTN1通过ANXA5–PKM2轴抑制高甘油三酯血症相关急性胰腺炎中的M1极化
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IF9.4
delete2026-10-17
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deleteYutong Zhu; Qihang Yuan; Xufeng Tao; Fangyue Guo; Yao Xu; Yu Wu; Shurong Ma; Xiaonan Zhang; Yunfei Dai; Lei Wang; Dong Shang; Hong Xiang
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