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ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5
论文数235
被引数
期刊论文 235
发表时间
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The Synthetic Role of PFAS in Drug Substance Manufacturing: An IQ Consortium Working Group Review on the Potential Impact of PFAS Restrictions on Patient Access to MedicinesPFAS在药物活性成分制造中的合成作用： IQ Consortium工作组关于PFAS限制对患者用药可及性潜在影响的综述
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteGemma Scotney; Kenneth J. Fraunhoffer; Ankur Jalan; Dazhan Liu; Andreas R. Rötheli; Robert Toner; Jonathan C. Tripp; Xin Yao
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Lipophilic Salts of High Melting Point Drugs Modulate Solid-State Properties and Organic Solubility to Enable Manufacturability of Amorphous Solid Dispersions高熔点药物的脂溶性盐调节固体状态性质和有机溶解度以实现非晶态固体分散体的可制造性
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteStella P. Petrova; Matthew M. Behymer; Naga K. Duggirala; Aaron Goodwin; Dana E. Moseson-Tarrh; Lynne S. Taylor
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Electrochemical Synthesis of Renewable Pyridines via Oxidative Ring Expansion通过氧化环扩张电化学合成可再生吡啶
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteSilja Hofmann; Astrid Kjær Steffensen; Alexandros Xanthopoulos; Anders Riisager; Helena Lundberg; Tobias Ankner
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An Aryl Alcohol Oxidase-Peroxygenase Catalyst System Enables Efficient Alcohol to Aldehyde Transformation芳醇氧化酶-过氧酶催化剂系统实现了醇到醛的高效转化
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-08-21
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PREAI
deleteYutong Wang; Nure Celebi; Paul Kerstholt; Sebastian Govaerts; Vlada B. Urlacher; Miguel Alcalde; Frank Hollmann
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Improved Synthesis of a Key Intermediate of Onapristone奥那司酮关键中间体的改良合成
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-08
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PREAI
deleteFei Lv; Qihua Zhao; Jiaoyang Feng; Ziyang Jia; Erin Zebrowski; Anjiang Yang; Boyu Zhong; Tony Yantao Zhang
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Some Items of Interest to Process R&D Chemists and Engineers过程研发化学家与工程师感兴趣的一些内容
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-07
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deleteThomas Verheyen; Paul F. Richardson; Andrei A. Zlota; Robert B. Kargbo; Alan Steven; David S. B. Daniels; Christopher C. Nawrat; Alexandre Barthelme; Sylvain Guizzetti; John Kremers; John Knight
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Process Development of the RIPK1 Inhibitor Oditrasertib Part 1: Continuous Synthesis of the Pyridine CoreRIPK1抑制剂奥迪特拉塞替布的工艺开发 第1部分：吡啶核心的连续合成
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-06
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PREAI
deleteGrace P. Ahlqvist; Nicholas L. Reed; Eileen M. Hoang; Boung Wook Lee; Douglas G. Fraser; Christopher P. Breen; Maia D. Carvalho; Sean Breen; Kiersten Campbell; Shruti Kumta; M. Grace Russell; Robert Yule; Brenda J. Burke; Jason S. Tedrow
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Development of a Scalable Synthesis for the Spirocyclic Benzoxepane–Pyridine Core of FXR Agonist HEC96719开发一种可扩展合成方法用于FXR激动剂HEC96719螺环苯并氧杂环庚烷-吡啶核心
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-01
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PREAI
deleteJiayang Zhang; Junwen Wu; Shengqiang Pan; Hong Chen; Zhongqing Wang; Xiaoyun Lu; Xinye Yang; Yingjun Zhang
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Development of a Commercial Manufacturing Process for Ganaplacide Phosphate甘帕拉西德磷酸盐的商业化生产工艺开发
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-07-01
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PREAI
deleteAlexandre Leclair; Thomas Ruch; Jibin Zhao; Xingxian Gu; Navid Dastbaravardeh; Xufan Wang; Jiong Ye; Zichen Jia; Andreas Kordikowski; Christian Mueller; Liqun Zhao; Jianguang Zhou; Serge Konrad
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Four-Step Continuous-Flow Total Synthesis of 4-Chloro-6; 7-dimethoxyquinoline; a Key Intermediate for Tyrosine Kinase Inhibitors4-氯-6,7-二甲氧基喹啉的四步连续流全合成；酪氨酸激酶抑制剂的关键中间体
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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PREAI
deleteXiaobin Liang; Xiaorong Zhou; Yian Luo; An Su; Hanqi Zhou; Jianli Chen; Fengfan Liu; Weike Su
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Case Studies on Enabling Data-Rich; Parallelized Kinetic Analysis for Process Optimization with the ReactALL Platform利用ReactALL平台实现数据丰富且并行化的动力学分析以优化过程的案例研究
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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PREAI
deleteVaishnavi N. Nair; Andreas R. Rötheli; Alan H. Cherney; Madeleine C. Deem; Melodie Christensen; Kevin Stone; Lu Han; Sebastien Monfette; Truong N. Nguyen
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Celebrating Lilly: 150 Years of Being a Medicine Company庆祝礼来公司：150年医药公司历程
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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deleteSarah O’Keeffe; Sarah E. Langan; Scott A. Frank; Qiang Yang
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Hydrogenation Process Development in a Data-Rich Environment数据丰富环境下的加氢工艺开发
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-30
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PREAI
deletePeter Sagmeister; Kensaku Matsunami; Giovanni Aprile; Darren A. Whitaker; Mohammed Janoudi; Thomas Toupy; Adrian Ramirez Galilea; Neda Nazemifard; Charles D. Papageorgiou; Aparajith Bhaskar; John Mack; Richard D. Braatz; Allan S. Myerson
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Heterogeneous Photochemical Process Intensification: Crystallization-Induced Dynamic Resolution of Amines多相光化学过程强化：胺结晶诱导的动态拆分
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-29
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deleteJonathan M. Meinhardt; Jiang Wang; Yufei Wei; Daniel P. Walker; Robert R. Knowles
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Development of a Second-Generation Stereoselective Manufacturing Process for a Key N-Hydroxyamidine Intermediate of GDC-6599 Enabled by Data Science and Mechanistic Understanding通过数据科学和机理理解开发GDC-6599关键N-羟基脒中间体的第二代立体选择性制造工艺
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-29
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PREAI
deleteJacob C. Timmerman; Allen Y. Hong; Kurt Püntener; Anna-Lena Glass; Sandro Tonazzi; Katarzyna A. Piechowicz; Maud Guillemot-Plass; José G. Napolitano; Breanna Conklin; Haiming Zhang; Francis Gosselin
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Scalable Preparation and Application of Ar2S+-CF3 TfO–可扩展的Ar2S+-CF3 TfO–制备与应用
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-26
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PREAI
deleteJia-Shuo Liu; Jin-Hong Lin; Ji-Chang Xiao
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Kilogram-Scale Process Development of Formoterol Fumarate: Synthesis; Identification; and LC–MS/MS Method Development for Trace-Level Quantification of N-Nitroso Impurity富马酸福莫特罗公斤级工艺开发：合成；鉴定；及N-亚硝基杂质痕量级定量LC–MS/MS方法开发
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-26
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PREAI
deleteKishor More; Vinayak Vele; Rajesh Kamath; Mustapha Mandewale; Mohan Anand Chandavarkar
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Scalable Synthesis of a Biaryl RASG12C Cancer Inhibitor as a Single Atropdiastereomer可扩展合成手性双芳基RASG12C癌症抑制剂作为单一阿托普对映异构体
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-26
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PREAI
deleteChristopher D. Parsons; Carl J. Mallia; Miriam Turner; Rachel H. Munday; Steven D. Bull
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A Practical and Scalable-Oriented Enantioselective Synthesis of (S)-Autumnaline实用且面向可扩展性的(S)-秋长春碱的不对称合成
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-25
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deleteAlessandro Brusa; Matteo Bottiglieri; Carola Tomassi; Francesco Feola; Daniele Lanaro; Andrea Bonetti; Gabriella Zappia; Federico Sala; Andrea Gambini; Mario Falzoni; Pietro Allegrini; Maria Luisa Gelmi; Massimiliano Aschi; Andrea Mazzanti; Fabio Pesciaioli; Armando Carlone
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Optimization of a Resolution Process Allowing Access to Both Enantiomers of the Versatile Chiral Phosphine Ligand sSPhos on Scale优化一种能够大规模制备手性膦配体sSPhos两种对映异构体的拆分过程
deleteORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
delete2026-06-25
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deleteHamzah Sharif; Thomas D. Svejstrup; Staffan Karlsson; Robert J. Phipps
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