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FUNCTIONAL & INTEGRATIVE GENOMICS

IF3.1
论文数289
被引数
期刊论文 289
发表时间
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Dissecting cell-type-specific genetic associations between colorectal cancer liability and thrombotic risk in peripheral blood immune cells解析外周血免疫细胞中结直肠癌易感性与血栓风险之间的细胞类型特异性遗传关联
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IF3.1
delete2026-10-29
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PREAI
deleteJiacheng Ying; Tianlong Ling; Zhengyuan Fang; Cheng Zhang; Yujie Bao; Jiayin Tang
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BILBO: a self-hosted platform for large-scale RNA-Seq analysis with a functional annotation clustering frameworkBILBO：一个用于大规模RNA-Seq分析的自托管平台，带有功能注释聚类框架
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IF3.1
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deleteVitor Luciano Costa da Silva; João Vitor Reis Alvarenga; Manoel Viana Linhares-Neto; Muhammad Noman; Antonio Chalfun-Junior
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miR-4284 alleviates calcium oxalate monohydrate crystal-induced renal tubular epithelial injury in HK-2 cells via directly targeting MMP10miR-4284通过直接靶向MMP10减轻草酸钙单水结晶诱导的HK-2细胞肾小管上皮损伤
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IF3.1
delete2026-10-29
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PREAI
deleteZenglin Cui; Yijing Zhang; Zixiang Li; Kun Wang; Junqi Wang
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Deep learning-based multiomics integration identifies AI-defined tissue regions associated with cancer-associated fibroblast enrichment and chemoresistance in muscle-invasive bladder cancer基于深度学习的多组学整合识别与肌层浸润性膀胱癌中癌症相关成纤维细胞富集和化疗耐药相关的AI定义组织区域
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IF3.1
delete2026-10-29
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PREAI
deleteChao Hu; Fan Wang; Qing Zhang; Hui Xu; Jing Huang; Xiujuan Xiong; Yuxin Huang; Weiming Lou; Yuanqiao He; Libin Deng; Xiongbing Lu
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SLC2A1 promotes chemo-immunotherapy resistance in lung adenocarcinoma by modulating the AKT signaling pathwaySLC2A1通过调控AKT信号通路促进肺腺癌对化免治疗的耐药性
deleteFUNCTIONAL & INTEGRATIVE GENOMICS
IF3.1
delete2026-10-28
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PREAI
deleteJingsheng Ruan; Mengxing Zhao; Ying Yuan; Jinlong Zhong
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Exploring the wild relatives of major cereals for abiotic stress tolerance through pan-transcriptomics通过泛转录组学探索主要谷物的野生亲缘种以研究其对非生物胁迫的耐受性
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IF3.1
delete2026-10-27
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PREAI
deleteLochan Karthikeyan; Jayakanthan Mannu; Santhi Madhavan Samyuktha; Uma Doraisamy; Dhashnamurthi Vijayalakshmi; D Kavithamani
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Integrated bulk and single-cell transcriptomics with virtual knockout analysis identifies FOS as an epithelial-associated candidate gene in chronic atrophic gastritis整合体细胞和单细胞转录组学，结合虚拟敲除分析，将FOS鉴定为慢性萎缩性胃炎中与上皮相关的候选基因
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IF3.1
delete2026-10-26
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PREAI
deleteShilong Li; Huiqiang Duan; Xin Liu; Meihua Shan; Zexuan Shen; Mingze Wu; Peiyao Wang; Qianze Yao; Weihua Fu
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Systems toxicology and multi-omics prioritize an MTBC-related computational signature in oral squamous cell carcinoma系统毒理学和多组学分析优先确定了与MTBC相关的口腔鳞状细胞癌的计算特征
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IF3.1
delete2026-10-26
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PREAI
deleteYongle Qiu; Chenlei Zhao; Haichun Wang; Jing Zhang; Jie Guo; Jiahong Zhao; Linyu Jin; Yi Cheng
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Integrating network pharmacology, genetically informed multi-omics and granulosa-cell experiments identifies dauricine and oleanolic acid as candidate CASP3-modulating compounds of Zhi-Bai-Di-Huang-Wan in female pubertal timing整合网络药理学、基因信息多组学及颗粒细胞实验，鉴定出粉防己碱和齐墩果酸为知柏地黄丸中调控CASP3的候选化合物，以影响女性青春期启动
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IF3.1
delete2026-10-26
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PREAI
deleteChung-Chih Liao; Shun-Fa Yang; Jung-Miao Li
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Genetic diversity, selection signatures, and breed-specific SNP marker identification in Baerchuke sheep巴儿楚克羊的遗传多样性、选择信号及品种特异性SNP标记鉴定
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IF3.1
delete2026-10-23
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PREAI
deleteHaichen Yang; Mahaba Rouzi; Peng Su; Yuhetian Zhao; Göran Andersson; Erik Bongcam-Rudloff; Maimaiti Aimaiti; Lin Jiang; Jilong Han; Min Yang
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scHGNN: A single-cell gene regulatory network inference method based on heuristic graph neural networksscHGNN：一种基于启发式图神经网络的单细胞基因调控网络推断方法
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IF3.1
delete2026-10-23
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PREAI
deleteTianjiao Zhang; Xiaopeng Teng; Hongfei Zhang; Zhongqian Zhao; Yang Li; Benzhi Dong; Guohua Wang
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Genome-wide identification and characterization of the PE/PPE gene family in Mycobacterium abscessus在人苍白杆菌中PE/PPE基因家族的全基因组鉴定和特征分析
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IF3.1
delete2026-10-21
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PREAI
deletePanqi Gao; Xinyu Wang; Longxiang Xie; Quanxin Long
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Long non-coding RNA LINC00657 aggravates atrial fibrosis in atrial fibrillation via the miR-144-3p/ROCK1 competing endogenous RNA axis长链非编码RNA LINC00657通过miR-144-3p/ROCK1竞争性内源RNA轴加剧心房颤动中心房纤维化
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IF3.1
delete2026-10-21
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PREAI
deleteXin Liang; Ziming Ou; Yahui Wang; Liqiu Yan
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A multi-omics study integrating single-cell transcriptomics, spatial transcriptomics, and mendelian randomization unveil the implication of TRDMT1 expression in T cells on the immunotherapeutic response and prognosis in breast cancer整合单细胞转录组学、空间转录组学和孟德尔随机化研究的多组学研究揭示了T细胞中TRDMT1表达在乳腺癌免疫治疗反应和预后中的意义
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IF3.1
delete2026-10-21
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deleteTingjun Li; Cheng Huang; Haolan Deng; Yifan You; Yu Jiang; Zhitang Wang; Qinglan Wang; Kunqi Chen; Debo Chen
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Integrative transcriptomic analysis reveals tumor-adjacent mucosal remodeling in colorectal cancer整合转录组学分析揭示结直肠癌中肿瘤邻近黏膜的重塑
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IF3.1
delete2026-10-17
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deleteSha Wu; Long Wu; Ruoshi Li; Xin Luo; Xueni Zhao; Liangrui Shi; Wei Liu; Lishan Ding; Zhaotong Cong; Zhuohong Li; Chuan Zheng; Chi Song
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NeuroMetBench: patient-aware evidence bounds for transcript-derived metabolic representations across cancer proteogenomic contextsNeuroMetBench：针对癌症蛋白质组学背景下转录衍生代谢表征的患者感知证据界
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IF3.1
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PREAI
deleteAbdsalam Bitar
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Retraction Note: miR-21-5p inhibits the growth of brain glioma cells through regulating the glycolysis mediated by PFKFB2撤稿声明：miR-21-5p通过调控PFKFB2介导的糖酵解抑制脑胶质瘤细胞生长
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IF3.1
delete2026-10-17
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PREAI
deleteLei Zhang; Jianmin Liu
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Polyploidization driven pan-genome structural remodeling and gene duplication mediated functional diversification in Panax人参泛基因组结构重塑由多倍体化驱动，基因功能分化由基因重复介导
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IF3.1
delete2026-10-14
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PREAI
deleteZhe Xu; Lubing Li; Jiangying Liu; Liying Feng
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Cross-scale genetic analysis prioritizes shared regulatory variation, cell-type contributions, co-expression programs, and exon-level patterns in atopic dermatitis and asthma跨尺度遗传分析优先考虑特应性皮炎和哮喘中的共享调控变异、细胞类型贡献、共表达程序和外显子水平模式
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IF3.1
delete2026-10-14
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PREAI
deleteChung-Chih Liao; Jung-Miao Li
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Analysis of the role of BAP31-related exosomal miRNAs as potential prognostic biomarkers for gastric cancerBAP31相关外泌体miRNAs作为胃癌潜在预后生物标志物的角色分析
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IF3.1
delete2026-10-13
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PREAI
deleteChuang Liu; Yufei Wu; Yanqiu Yang; Wanting Liu; Bing Wang; Tianyi Wang
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