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CPT-Pharmacometrics & Systems Pharmacology

IF3
论文数123
被引数
期刊论文 123
发表时间
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Aflibercept 8 mg: From Ocular Clearance to Pharmacodynamic Duration阿柏西普8 mg：从眼部清除到药效持续时间
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-10-11
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deleteDaniele Veritti; Valentina Sarao; Paolo Lanzetta
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Causal Exposure‐Response Analysis: Estimands, Time‐Varying Confounding, and the Parametric g‐Formula因果暴露-反应分析：目标统计量、时变混淆和参数化g-公式
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-10-09
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PREAI
deleteNathan Braniff
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Integrating a Tumor Size‐Overall Survival Model Into a Spatial Quantitative Systems Pharmacology Framework for Antibody‐Drug Conjugates in Non‐Small Cell Lung Cancer将肿瘤大小-总生存期模型整合到非小细胞肺癌抗体偶联药物的时空定量系统药理学框架中
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-10-09
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PREAI
deleteMehdi Nikfar; Richard Franzese; Herbert Struemper; Brett Howell; Murad Melhem
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Dynamic Prediction of Clinical Endpoints in Survival Analysis With Machine and Deep Learning: A Systematic Review and Regulatory Perspective机器学习与深度学习在生存分析中临床终点动态预测的系统综述与监管视角
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-10-08
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PREAI
deleteXinyi Liu; Shuai Shao; Dorothee Semiond; Malidi Ahamadi
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Application of an Open-Source Modular Framework for Pharmacokinetic, Pharmacodynamic, and Safety Simulations to Anti-Tuberculosis Drugs开源模块化框架在抗结核药物药代动力学、药效学和安全性模拟中的应用
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-10-07
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deleteOAAI
deleteMarco Siccardi; Nina Nauwelaerts; Raphaëlle Lesage; Diane Lefaudeux; Vanessa Baier; Venetia Karamitsou; Cleo Demeester; Miao-Chan Huang; Alexander Kulesza; Stephan Schaller
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Simultaneous Population PKPD Analysis of Belantamab Mafodotin, Soluble BCMA, and Serum M-Protein in Relapsed/Refractory Multiple Myeloma贝兰塔玛波汀、可溶性BCMA和血清M蛋白在复发/难治性多发性骨髓瘤中的同步群体药代动力学-药效学分析
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-30
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deleteJohn D. Clements; Inmaculada C. Sorribes; Josh Kaullen; Christine Neumar; Adekemi Taylor; Mun Sang Yue; Xi Chen; Herbert Struemper; Geraldine Ferron-Brady
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Population Pharmacokinetics of Dolutegravir in Plasma and Cerebrospinal Fluid in Adults Living With HIVHIV感染者中多替拉韦在血浆和脑脊液中的群体药代动力学
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-30
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deleteMohammed W. Ali; Sam Nightingale; Tracy Kellermann; John Joska; Alan Winston; Saye Khoo; Joseph F. Standing; Eric H. Decloedt; Ahmed A. Abulfathi
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Development, Early Verification and Application of a North American Pediatric PBPK Model, Comparison With the North European Pediatric Population北美儿科PBPK模型的开发、早期验证与应用，并与北欧儿科人群进行比较
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-25
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deleteTrevor N. Johnson; Fiskani Kondowe; Joyce van der Heijden; Saskia N. de Wildt; Iain Gardner; Karen Rowland Yeo
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PMxAgent: An Agentic Platform for PharmacometricsPMxAgent：一个药代动力学代理平台
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-25
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deletePeter Bloomingdale; Antari Khot
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A Practical Tutorial on Physics-Informed Networks for Pharmacometrics and Quantitative Systems Pharmacology药代动力学和定量系统药理学中物理信息网络的实用教程
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-23
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deleteNazanin Ahmadi Daryakenari; Mohammad Kohandel
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Population Pharmacokinetics of Topical Timolol Maleate Gel in Healthy Volunteers and Infants With Superficial Infantile Hemangioma马来酸噻吗洛尔凝胶外用后健康志愿者和浅表婴儿血管瘤患儿的群体药代动力学
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-21
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deleteLi Li; Yanming Li; Fan Hu; Deming Wang; Ning Sun; Qingheng Meng; Qin Yu; Ling Xu; Libo Zhao; Lin Ma
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A Quantitative Systems Pharmacology Model of Human Leucine Metabolism人类亮氨酸代谢的定量系统药理学模型
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-18
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deleteJ. Cody Herron; Anna Sher; Yingbo Ma; Elisabeth Roesch; Sebastian Miculța-Câmpeanu; Christopher Rackauckas; Kevin J. Filipski; Rachel Roth Flach; Theodore R. Rieger; Cynthia J. Musante; Richard Allen
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Pharmaceutical Industry Perspectives on Exposure-Response Confounding in Large Molecule Therapeutics: Results From an IQ Consortium Survey制药行业对大分子治疗药物中暴露-反应混杂因素的观点：IQ联盟调查结果
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteEngie Salama; Manisha Lamba; Sihem Ait-Oudhia; Ellen Wang; Dorothee Semiond; Zhang Li; Tao Long; Satyendra Suryawanshi; Leticia Arrington; Wei Gao; Xiaowen Guan; Hugh Giovinazzo; Dale Miles; David C. Turner
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Transporter-Drive Interstitial Tissue Exposure and Pharmacodynamic Response of Meropenem in Sepsis: A Mechanistic PBPK Modeling Study转运蛋白驱动的美罗培南在败血症中的间质组织暴露和药效学反应：一项机制性PBPK建模研究
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteLaura Ben Olivo; Jessica Luisa Silva de Lemos; Vinicius Jardim Rodrigues; Bibiana Verlindo de Araújo
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Net Renal Drug Secretion Critically Requires Significant Contribution of Basal Uptake Transporters: Perspective From Mechanistic Kidney Model Simulation and Integration of Clinical and In Vitro Data净肾脏药物分泌严重依赖于基础摄取转运体的显著贡献：基于机制性肾脏模型模拟和临床与体外数据整合的视角
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteToshiaki Tsuchitani; Masatoshi Tomi; Yuichi Sugiyama
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Integrating CRRT as a Virtual Organ Into Physiologically Based Pharmacokinetic Modeling to Optimize Antimicrobial Dosing in Septic Patients将连续性肾脏替代疗法整合为生理药代动力学模型中的虚拟器官，以优化脓毒症患者的抗菌药物剂量
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteYuanming Xing; Yijing Zhang; Chuqi Bai; Yulan Qiu; Chuhui Wang; Lei Chen; Taotao Wang; Jiaojiao Chen
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Development of Integrated Parent–Metabolite Pharmacokinetic Model With Apparent Presystemic Metabolism to Characterize the Disposition of Alverine开发包含表观前系统代谢的集成母体-代谢物药代动力学模型以表征阿维林处置特征
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteAra Cho; Hyeon-Cheol Jeong; MinJu Kim; Inkyung Cho; Hyeon-Jeong Na; Kyong-Cheol Ko; Yoon-Jee Chae; Kyeong-Ryoon Lee
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Model-Based Tacrolimus Dosing Using the Population Pharmacokinetic Analysis Under the Nirmatrelvir/Ritonavir Therapy基于群体药代动力学分析的尼玛特雷韦/利托那韦治疗下的模型化他克莫司剂量给药
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteKotaro Itohara; Yoshiki Katada; Takahiro Hatayama; Toshiaki Igarashi; Jiro Ogura; Tomoki Fukushima; Shingo Yamazaki; Masato Homma; Takashi Niwa; Yoshiaki Kato; Nanae Yamamoto; Hideyuki Terazono; Hideo Shiohira; Tomohiro Terada; Ikuko Yano
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Semi-Mechanistic Modeling of S-531011, a Humanized Anti-CCR8 Monoclonal Antibody, for Prediction of CCR8 Receptor Occupancy in Human Tumor Tissues人源化抗CCR8单克隆抗体S-531011的半机理建模，用于预测人类肿瘤组织中的CCR8受体占有率
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteDaichi Yamaguchi; Wataru Nogami; Yudai Sonoda; Hitomi Morihara; Takayuki Katsube
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Adjoint and Unrolled Automatic Differentiation for Laplace-Approximated Likelihoods in Population PK and PK/PD Models用于群体PK和PK/PD模型中拉普拉斯近似似然函数的伴随与展开自动微分
deleteCPT-Pharmacometrics & Systems Pharmacology
IF3
delete2026-09-16
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deleteGuido H. Jajamovich; William Holmes; Chih-Wei Lin; Khamir Mehta
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