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BIOORGANIC & MEDICINAL CHEMISTRY

IF3
论文数193
被引数
期刊论文 193
发表时间
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Structure–activity relationships of hybrid paraisariamide/ternatin cyclic heptapeptides杂合对虾胺/特纳丁环七肽的结构-活性关系
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-23
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deleteOAAI
deleteYui Tagami; Takumi Arai; Elizabeth J. Mumby; Naoya Iwamoto; Kazuya Kobayashi; Kerry L. McPhail; Shinya Oishi
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Linear and SS cyclized radiopeptides for estrogen receptor targeting线性及S-S环化的放射性肽用于雌激素受体靶向
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-21
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PREAI
deleteSonal Gupta; Manoj Kumar; Krishna Mohan Repaka; Ananda Majumdar Guha; Mahesh Subramanian; Ajit A. Kengar; Drishty Satpati
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Structural expansion of benzimidazole-based FLAP inhibitors: identification of dual-action agents targeting leukotriene biosynthesis and Cancer cell proliferation苯并咪唑类FLAP抑制剂的构效关系扩展：鉴定靶向白三烯生物合成和癌细胞增殖的双功能药物
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-18
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PREAI
deleteMehmet Karataş; Hannes Engelbrecht; Paul M. Jordan; Özge Akbulut Çalışkan; Kübra Çalışkan; Burcu Çalışkan; Oliver Werz; Erden Banoglu
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Recent discoveries of CRBN-binding molecular glue degraders: Focus on protein kinases近期发现的CRBN结合分子胶降解剂：聚焦于蛋白激酶
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-09
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deleteOAAI
deleteInjeoung Hwang; Wooyoung Hur
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Development of dihydroquinolizinone (DHQ)-based inhibitors for suppression of hepatitis B viral infections基于二氢喹啉基啶酮（DHQ）的抑制剂的开发用于抑制乙型肝炎病毒感染
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-07
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PREAI
deleteHan Yu; Zuo Yinglin; Jiang Zhidong; Liu Rong; Xu Honggui; Tang Lin; Liu Xinchang; Yan Guanghua; Yang Chuanwen; Wang Jiancheng; Zhang Lei; Zhang Yingjun
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Novel trans-stilbene-phytophenol conjugates as potent tubulin-targeting antiproliferative agents新型反式-stilbene-植物酚缀合物作为强效微管靶向抗增殖剂
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-06
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PREAI
deleteMitodru Misra; Satyajit Halder; Puja Bag; Anirban Manna; Somesh Roy; Asanjan Brahmachari; Ankur Kumar; Utsab Debnath; Gautam Brahmachari; Kuladip Jana
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Selective PTP1B inhibition by A-1331852: Uncompetitive kinetics and computational evidence for C-terminal engagementA-1331852对PTP1B的特异性抑制：反竞争性动力学及C末端结合的计算机证据
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-03
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deleteNathaly Vasquez-Martínez; Alejandro Sosa-Peinado; Francisco Cortés-Benítez; Martín González-Andrade
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Targeting the putative allosteric site J of cannabinoid receptor type 2 with peptide modulators: From mechanistic investigation to candidate identification靶向大麻素受体2型假想别构位点J的肽调节剂：从机制研究到候选物识别
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-02
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PREAI
deleteXinyi Zhang; Zhihui Chen; Mengxiang Su
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Pyridine-core scaffolds suppress A549 lung cancer cell progression: Evaluation of the antiproliferative activity, apoptosis, ROS generation, clonogenic suppression, and EGFR expression吡啶核心骨架抑制A549肺癌细胞进展：抗增殖活性、凋亡、ROS生成、克隆抑制和EGFR表达的评估
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-10-01
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PREAI
deleteK.B. Sachin Kumar; N.D. Satyanarayan; L. Vedavi; H. Vishwas; H.M. Kumaraswamy
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Synthesis of vincamine derivatives via Pictet-Spengler reaction leads to additional unexpected oxidized spirocyclic byproducts - initial investigations in cytotoxic, anti-diabetic, enzyme inhibition as well as anti-herbivore activities通过Pictet-Spengler反应合成长春胺衍生物导致产生额外的、意外的氧化螺环副产物——在细胞毒性、抗糖尿病、酶抑制以及抗食草动物活性方面的初步研究
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-30
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deleteChristina Rodler; Dominik Wenisch; Zehra Özel; Michael Jakupec; Johann Schinnerl; Lothar Brecker
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Neutral sphingomyelinase 2 inhibitors based on the imidazo[1,2-b]pyridazin-3-amine scaffold基于咪唑并[1,2-b]吡嗪-3-胺骨架的中性鞘磷脂酶2抑制剂
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-30
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deleteBiswajit Kundu; Ajit G. Thomas; Matthew Stremlau; Ayush Bajaj; Louis Mueller; Arina Ranjit; Rana Rais; Barbara S. Slusher; Takashi Tsukamoto
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Synthesis of axially chiral benzochalcogenophene derivatives and their anti-proliferative activities in cancer cells轴手性苯并硫/硒/碲杂环戊二烯衍生物的合成及其在癌细胞中的抗增殖活性
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-29
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PREAI
deleteKanon Nakaie; Takumi Inoue; Rinko Mikyu; Nanami Otsuki; Eishi Ashihara; Takumi Furuta
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Hypoxia-activated 2-nitroimidazole-brusatol carbonate prodrugs for enhanced gastric cancer therapy with reduced systemic toxicity乏氧激活的2-硝基咪唑-布拉斯他汀碳酸酯前药用于增强胃癌治疗并降低全身毒性
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-28
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PREAI
deleteJichong Li; Xuelan Ma; Zijian Liu; Xinyu Chang; Yifan Wei; Ning Ma; Xiaoling Liu; Xuan Zhang; Yiwei Sun; Hao Zhou; Qingbo Liu; Shao-Jiang Song
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Criteria-guided selection of alternative zinc-binding groups of HDAC3 inhibitors using in silico and in vitro approaches基于计算和体外方法指导的选择HDAC3抑制剂替代锌结合基团的准则
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-25
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deleteThabo Brighton Makgoba; Samuel Egieyeh; Erika Kapp; Jacques Joubert
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Rivastigmine-centered molecular hybridization strategies for multi-targeted intervention in Alzheimer's disease: Advances (2020–2026)利凡斯明为中心的分子杂交策略用于阿尔茨海默病多靶点干预：进展（2020–2026）
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-25
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PREAI
deleteNitin Kumar; Virendra Kumar Kushwaha; Gourav Singh; Smriti Ojha; Alok Kumar Dash; Gauri Shankar
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Design, synthesis, and biological evaluation of novel dihydropyrimidinone imines as potent anticancer agents targeting AKT to induce cell cycle arrest and apoptosis in breast Cancer cells新型二氢嘧啶酮亚胺的设计、合成及其作为靶向AKT以诱导乳腺癌细胞周期停滞和凋亡的强效抗癌剂的生物评价
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-23
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PREAI
deleteMarian N. Gerges; Ahmed A. Noser; Eman G. Ibrahim; Thoria Diab
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Design, synthesis and biological evaluation of a series of new, potent FLT3 PROTAC degraders with rigid linkers一系列新型、强效FLT3 PROTAC降解剂的刚性连接子设计、合成与生物活性评价
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-19
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PREAI
deleteLicheng Zhou; Yinglong Chen; Jiahe Li; Yayuan Yang; Wenyan Liu; Yingfan Liu; Bohai Fan; Yang Zhou; Jinwei Zhang; Xiaomei Ren; Ke Ding; Weixue Huang; Zhen Wang; Fengtao Zhou
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Redirecting MurD inhibitor preference toward MurD2 through glutamate stereochemical inversion通过谷氨酸立体化学反转将MurD抑制剂的偏好重定向至MurD2
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-15
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PREAI
deleteZhuang Qian; Yu Nakashima; Tohru Dairi; Hiroyuki Morita
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Design, synthesis, biological and computational evaluation of Thieno[3,2-d] pyrimidine-based inhibitors of JAK3 kinase基于噻吩[3,2-d]嘧啶的JAK3激酶抑制剂的分子设计、合成及生物与计算评价
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-12
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PREAI
deletePoowadon Fukasem; Kittitat Jaengwang; Duangkamol Gleeson; Robert G. Britton; Kiattawee Choowongkomon; M. Paul Gleeson
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An in vitro comparative study of cefiderocol, siderophore-aztreonam and siderophore-daptomycin conjugates against select gram-negative bacteria体外比较研究：铁载体头孢地尔、铁载体阿维巴坦和铁载体达托霉素缀合物对选择性革兰氏阴性菌的作用
deleteBIOORGANIC & MEDICINAL CHEMISTRY
IF3
delete2026-09-11
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deleteRui Liu; Patricia A. Miller; Marvin J. Miller
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