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cpt: pharmacometrics & systems pharmacology

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论文数102
被引数
期刊论文 102
发表时间
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Optimizing Clinical Study Designs for CAR-T Cell Therapy: Development of an Efficient Sampling Strategy Through Optimal Experimental Design优化CAR-T细胞治疗的临床研究设计：通过最优实验设计开发高效的采样策略
deletecpt: pharmacometrics & systems pharmacology
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delete2026-07-07
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deleteFenja Klima; Anna M. Mc Laughlin; Robin Michelet; Wilhelm Huisinga; Katy Haussmann; Annette Künkele; Andrew C. Hooker; Charlotte Kloft
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Integrated Population Pharmacokinetic Analysis of Intravitreal Aflibercept Drug Products玻璃体内注射阿柏西普药物产品的集成群体药代动力学分析
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-30
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deleteSébastien Bihorel; Joannellyn Chiu; Jason Chittenden; Thomas Eissing; Kenneth C. Turner; Joachim Höchel; Torsten Zimmermann; Zhongqing Will He; John D. Davis; A. Thomas DiCioccio; Lutz O. Harnisch
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Development and Use of a Population Pharmacokinetic Model for Characterizing the Pharmacokinetics of Vonoprazan in Pediatric Patients开发和应用一种群体药代动力学模型以表征沃诺拉坦在儿科患者中的药代动力学特征
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-30
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deleteDarcy J. Mulford; Axel Facius; Galen Witt; Colin W. Howden; Thomas Wagner; Eckhard Leifke; Carmelo Scarpignato
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Butorphanol Pharmacokinetics Across Species: Meta-Analysis Integrating Allometric Scaling and Minimal Physiologically Based Pharmacokinetic Modeling丁丙诺啡药代动力学跨物种研究：整合异速生长缩放和最小生理基础药代动力学模型的Meta分析
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-27
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deleteAhmed M. Saeed; William J. Jusko
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Accelerating Subcutaneous Drug Development: A Mechanistic Absorption Model for the Open Systems Pharmacology Framework加速皮下药物开发：开放式系统药理学框架下的机制性吸收模型
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-25
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deleteMoriah Pellowe; Ilse Dubbelboer; Erik Sjögren
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Population Pharmacokinetics and Pharmacodynamics of Paracetamol in Malaysian Patients With Plasmodium knowlesi Malaria马来亚患者中扑热息痛的群体药代动力学和药效学研究
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-22
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deleteThanaporn Wattanakul; Daniel J. Cooper; Katherine Plewes; Matthew J. Grigg; Giri S. Rajahram; Timothy William; Arjen M. Dondorp; Michael D. Edstein; Geoffrey W. Birrell; Nicholas M. Anstey; Richard M. Hoglund; Bridget E. Barber; Joel Tarning
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Development of an Agent-Based Model to Investigate Durability of Factor IX Activity in Hemophilia B Patients Treated With Etranacogene Dezaparvovec基于代理模型开发以研究接受Etranacogene Dezaparvovec治疗的血友病B患者中凝血因子IX活性的持久性
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-20
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deleteYuezhe Li; Partha Nandy; Eric Jordie; Timothy Knab; Karsten Peppel; Daniel C. Kirouac; A. Katharina Wilkins; Silpa Nuthalapati
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Polymyxin B Intravenous Administration Strategy Guided by Minimum Inhibitory Concentration in Critically Ill Patients With Pulmonary Infection: Insights From PBPK Modeling基于最小抑菌浓度的多黏菌素B静脉给药策略在重症肺部感染患者中的应用：PBPK建模的启示
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-19
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deleteShengnan Zhang; Nan Yang; Ruwei Yang; Yuanfang Qin; Tingting Wu; Cuifang Wu; Yueliang Xie; Jingjing Liu; Chun Liu; Qi Pei
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The Empirical Bayes Variational Autoencoder—A Neural ODE Approach for Population Modeling in Pharmacology经验贝叶斯变分自编码器——一种用于药理学群体建模的神经ODE方法
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-17
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deleteMarcus Baaz; Anders Sjöberg; Mats Jirstrand
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PK and PK/PD Modeling of Bcl2 Inhibitor S65487 in Patients With AML and Investigation of Nonlinearity With MicrodosingBcl2抑制剂S65487在AML患者中的药代动力学和药代动力学/药效动力学建模及微剂量下非线性特征的探讨
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-17
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deleteChloé Burlot; François Riglet; Mathilde Romagnoli; Ariane Leconte; Audrey Delmas; Antonin Schmitt; Sylvain Fouliard
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PMX-CovEval: A Framework Including a Simulated Pharmacokinetic Database for Covariate Model Building Methods BenchmarkingPMX-CovEval：一个包含模拟药代动力学数据库的框架，用于协变量模型构建方法的基准测试
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-17
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deleteMélanie Karlsen; Jérôme Azé; Sandra Bringay; Pascal Poncelet; David Fabre; David Marchionni; Elisa A. M. Calvier
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Cellular Heterogeneity in Drug Uptake Amplifies Pharmacodynamic Variability: A Stochastic PK-PD Analysis细胞异质性在药物摄取中放大了药效动力学变异性：一项随机PK-PD分析
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-15
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deleteNhung Hong-Thi Duong; Tuan Ngoc Do; Tien Tran-Nam Nguyen; Khanh Quoc Phan; Lap Thi Nguyen
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AI-Powered Lesion-Level Tumor Growth Inhibition Modeling Improves Model Stability and Prognostic Association With PFSAI驱动的病灶级肿瘤生长抑制建模提高了模型稳定性并与PFS预后关联
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-13
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deleteAlan Liu; Chong Duan; Kevin Maresca; Yazdi K. Pithavala; Jen-Tang Lu; Cathy Cen Guo; Jennifer E. Hibma
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Physiologically Based Pharmacokinetic Model to Predict Drug–Drug Interactions With the Antibody–Drug Conjugate Trastuzumab Deruxtecan基于生理药代动力学模型预测抗体偶联药物曲妥珠单抗德鲁克坦的药物相互作用
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-09
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deleteAkiko Watanabe; Katherine L. Gill; Kuan-Fu Chen; Hannah M. Jones; Mailys De Sousa Mendes; Iain Gardner; Masakatsu Kotsuma
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Evaluation of the Current ATTR-CM Treatment Landscape via a Mathematical Model of TTR Dissociation and Amyloid Formation通过TTR解离和淀粉样蛋白形成数学模型评估当前ATTR-CM治疗格局
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-08
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deleteStevan Methven Jeknić; Travis A. Ahn-Horst; Alan X. Ji; Jin Hyun Ju; Morgan Paull; Sun-Gou Ji; Uma Sinha
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Modeling Peak Expiratory Flow in Patients With Asthma and Quantifying Treatment Effects Using a Mixed-Effects Hidden Markov Model哮喘患者峰值呼气流量的建模及使用混合效应隐马尔可夫模型量化治疗效果
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-06
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deleteLudvig Jakobsson; Marcus Baaz; Jacob Leander; Philip Gerlee; Mats Jirstrand
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Simulation Framework to Investigate Efficacy and Ocular Safety of Belantamab Mafodotin Combinations in Relapsed/Refractory Multiple Myeloma模拟框架用于研究Belantamab Mafodotin联合用药在复发/难治性多发性骨髓瘤中的疗效和眼部安全性
deletecpt: pharmacometrics & systems pharmacology
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delete2026-06-04
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deleteFernando Carreño; Martijn van Noort; Adekemi Taylor; Stefan Zeiser; Theodoros Papathanasiou; Teun M. Post; Yi Ting (Kayla) Lien; Yu Liu Ho; Geraldine Ferron-Brady
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Pharmacokinetic Model Based Sensitivity Analysis to Lower Recruitment Burden for Young Children Requiring Intravenous Immunoglobulin G Replacement基于药代动力学模型的敏感性分析以降低需要静脉注射免疫球蛋白G替代治疗的儿童受试者招募负担
deletecpt: pharmacometrics & systems pharmacology
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delete2026-05-31
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deleteTodd Dumas; Shahram Mehr; Rebecca Avila; Amy Doman; Kaitlin Kestenberg; Isaac Melamed
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External Evaluation of Population Pharmacokinetic Models of Cabotegravir, During Its Oral and Intramuscular Administration in HIV-Infected Patients卡博特egravir在口服和肌肉注射给药于HIV感染患者期间的群体药代动力学模型的外部评价
deletecpt: pharmacometrics & systems pharmacology
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delete2026-05-22
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deleteQuentin Renou; Nadège Néant; Alexandre Destere; Jennifer Lagoutte-Renosi; Matthieu Grégoire; François Parant; Sébastien Lalanne; Florian Lemaitre; Peggy Gandia; Nicolas Venisse; Stéphane Bouchet; Minh P. Lê; Patrice Muret; Gilles Peytavin; Caroline Solas; Sihem Benaboud; the CARLA Study Group
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Physiologically Based Pharmacokinetic Modeling of Elexacaftor/Tezacaftor/Ivacaftor in Infants With Cystic Fibrosis基于生理学的药代动力学模型在囊性纤维化婴儿中的Elexacaftor/Tezacaftor/Ivacaftor研究
deletecpt: pharmacometrics & systems pharmacology
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delete2026-05-22
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deleteNgoc Hoa Truong; Sihem Benaboud; Naïm Bouazza; Eric Deneuville; Anne Mornand; Philippe Reix; Mélanie Ribault; Pierre-Régis Burgel; Léo Froelicher-Bournaud; Steeve Rouillon; Mohammed Rohi Sanoufi; Gabrielle Lui; Saïk Urien; Jean-Marc Tréluyer; Isabelle Sermet-Gaudelus; Frantz Foissac; Modul-CF study group
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