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experimental & molecular medicine

IF
论文数173
被引数
期刊论文 173
发表时间
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Urolithin A activates mitophagy via the AMPK–mTOR axis and modulates the gut–ceramide axis to ameliorate cardiac remodeling in HFpEF尿石素A通过AMPK–mTOR轴激活线粒体自噬，并通过调节肠道–鞘脂轴改善HFpEF的心脏重塑
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delete2026-07-10
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deleteHangyul Song; Chahyeon Yun; Yunju Choi; Wooju Jeong; Yumin Kim; Jaeyoung Kim; Ju-Yeon Lee; Dongryeol Ryu; Sang-Wook Park; Chang-Myung Oh
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Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation由SIRT7催化的SRF去乙酰化可防止腹主动脉瘤形成
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delete2026-07-08
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deleteYacheng Xiong; Jing Chen; Weiting Lu; Yu Liu; Chang Sheng; Shuai Liu; Baohui Xu; Yongqing Li; Baihong Pan; Wei Wang
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Granzyme K CD8⁺ T cells with tissue-resident features promote intestinal inflammation in patients with Crohn’s disease具有组织驻留特征的Granzyme K CD8⁺ T细胞促进克罗恩病患者肠道炎症
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deleteYoonho Lee; Tae-Young Kim; Yongjae Kim; Jiwon Baek; Hwan Park; Do Kyung Yoon; Sung Wook Hwang; Jong Lyul Lee; Sang Hyoung Park; Jihun Kim; Suk-Kyun Yang; Buhm Han; Mi-Na Kweon; Kyuyoung Song; Yong Sik Yoon; Byong Duk Ye; Ho-Su Lee
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Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity脂肪细胞OX40L促进肥胖中脂肪组织T细胞活化和胰岛素抵抗
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deleteJianfeng Song; Qin Zeng; Yayi Jiao; Xiaoxiao Sun; Limin Xie; Jingpei Qiu; Yujin Ding; Wanyu Hu; Fanqi Wang; Biling Huang; Wuqian Mai; Ying Mei; Dandan Wang; Lan Xie; Xiang Xiao; Wei Liu; Willa A. Hsueh; Xian C. Li; Tuo Deng
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Multiscale systems modelling of communication networks in brain metastasis脑转移中通信网络的多尺度系统建模
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deleteJu Young Ahn; Wenjuan Dong; Stephen TC Wong; Hong Zhao
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Integrated single-cell and spatial transcriptomics reveal stromal–immune–vascular crosstalk in patients with interstitial cystitis/bladder pain syndrome整合单细胞与空间转录组学揭示间质性膀胱炎/膀胱疼痛综合征患者基质-免疫-血管之间的串扰
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deleteByulA Jee; IJun Kim; Cheol Lee; Yeon Jeong Kim; Kyunghee Park; Ji-Hee Sung; Inwoo Hwang; Jung-Sun Kim; Kyu-Sung Lee; Kwang Jin Ko; Minyong Kang
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Protein arginine methyltransferases coordinate mitochondrial stress adaptation and neuromuscular function蛋白精氨酸甲基转移酶协调线粒体应激适应和神经肌肉功能
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deleteJu-Hyeon Bae; Chang-Lim You; Jeongmin Park; Jong-Sun Kang
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Establishing human immune system mice: application, opportunity, and challenges建立人源化免疫系统小鼠：应用、机遇与挑战
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deletePei-Chuan Chiang; Hung Lee-Chan; Yungling Leo Lee
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TRPC6 loss triggers mitochondrial dysfunction that drives white adipose tissue vulnerability to obesity and insulin resistanceTRPC6缺失触发线粒体功能障碍，进而驱动白色脂肪组织对肥胖和胰岛素抵抗的易感性
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deletePhan Anh Nguyen; Kyu-Hee Hwang; Duyen Thi Thuy Tran; Tae Sic Lee; Kyu-Sang Park; Seung-Kuy Cha
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Apelin–APLNR pathway across development, inflammation, and vascular remodeling: an endothelial perspectiveApelin–APLNR通路在发育、炎症和血管重塑中的作用：从内皮细胞的角度
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deleteHongryeol Park; Ralf H. Adams; Kee-Pyo Kim
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Oligodendrocyte prosaposin restores subarachnoid haemorrhage-induced consciousness impairment少突胶质细胞前唾液酸蛋白恢复蛛网膜下腔出血诱导的意识障碍
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deleteHaiying Li; Xiang Li; Zhongmou Xu; Chang Cao; Jinxin Lu; Haojie Ding; Lei Bai; Jin Tao; Lu Peng; Jiping Tang; Gang Chen
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ISGylation-mediated stabilization of CYP4Z1 fuels breast cancer initiation and progressionISG化介导的CYP4Z1稳定化促进乳腺癌的起始和进展
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deleteYin Yuan; Yu Lu; Xuedan Han; Yidong Zhang; Qianqian Guo; Hong Yao; Qiyi Yu; Manzhen Zhou; Xinting Huang; Hongqi Wang; Miaomiao Niu; Jun Yin; Haibo Rong; Lei Huang; Xiaoman Li; Shengtao Xu; Lufeng Zheng
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Sphingosine-1-phosphate receptor 1 signaling stimulates human pluripotent stem cell-derived cardiomyocyte differentiation and maturation鞘氨醇-1-磷酸受体1信号刺激人源性多能干细胞分化为心肌细胞及成熟
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deleteWon Dong Yu; Seul-Gi Lee; Kwang Bo Jung; Sung-Ae Hyun; Young-Dae Kim; Ye Seul Son; Hana Lee; Hyun-Soo Cho; Dae-Soo Kim; Kyung Jin Lee; Jongman Yoo; C-Yoon Kim; Mi-Ok Lee; Ohman Kwon; Mi-Young Son
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Coordinated DNA 5-mC and RNA m5C methylation epigenetically regulates MZF1 splice variants to drive EGFR-TKI resistance协同的DNA 5-甲基胞嘧啶和RNA 5-甲基胞嘧啶甲基化通过表观遗传学调控MZF1剪接异构体以驱动EGFR-TKI耐药性
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deleteHuan Zhang; Yutong Pang; Bin Liu; Dongfeng Wang; Niying Zhao; Xiaojue Wang; PanJian Wei; Jie Lin; Shuye Lin
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Metabolic reprogramming of myeloid cells in cancer: from lactate–NAMPT axis to AI-guided therapeutics肿瘤中髓系细胞的代谢重编程：从乳酸-NAMPT轴到AI指导的治疗策略
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deleteIn-Gu Lee; Keehoon Jung
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Exercise-stimulated primary cilia on preosteoclasts promote periosteal-bone formation运动刺激的破骨前细胞初级纤毛促进骨膜骨形成
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deleteJin-Man Kim; Young-Sun Lee; Min Ji Kim; Yewon Kim; Ho Kyoung Kim; Sung-Ah Moon; Hanjun Kim; Han Jin Cho; Sunghoon Kim; Seung Hun Lee; Min-Seon Kim; Young-Bum Kim; Jung-Min Koh
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In-depth multimodal validation of 18F-THK5351 for imaging monoamine oxidase-B-mediated reactive astrogliosis in Alzheimer’s and related neurodegenerative diseases18F-THK5351在阿尔茨海默病及相关神经退行性疾病中成像单胺氧化酶-B介导的反应性星形胶质细胞增生的多模态深度验证
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deleteHeejung Chun; Wongu Youn; Hyunkeong Lim; Ryuichi Harada; Hae Young Ko; Jiyoung Yoon; Soo-Jin Oh; Philipp Seemann; Joseph G. Pepe; Brian K. Shoichet; Hye Won Lee; Shozo Furumoto; Nobuyuki Okamura; Mijin Yun; C. Justin Lee
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Retraction Note: Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells撤稿说明：固有免疫受体刺激对脑驻留细胞摄取和降解细胞外α-突触核蛋白的影响
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delete2026-06-29
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deleteChangyoun Kim; Somin Kwon; Michiyo Iba; Brian Spencer; Edward Rockenstein; Michael Mante; Anthony Adame; Soo Jean Shin; Jerel A. Fields; Robert A. Rissman; Seung-Jae Lee; Eliezer Masliah
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Metastasis-related genomic aberrations and evolutionary trajectory in uveal melanoma葡萄膜黑色素瘤的转移相关基因组异常与进化轨迹
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deleteChang Hyun Nam; Yong Joon Kim; Jeonghwan Youk; Hyo Song Park; Young Seok Ju; Christopher Seungkyu Lee
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Keratin 18 functions as a lactyltransferase to trigger necroptosis in diabetic kidney disease by modulating Fas transcription角蛋白18通过调节Fas转录作为乳酰转移酶触发糖尿病肾病中的坏死性凋亡
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delete2026-06-12
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deleteQiao Zhao; Xu Liu; Yangliang Yang; Fufen Meng; Zhipeng Meng; Minmin Zhu
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