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CAG-targeting artificial miRNA with reduced off-target risk for efficient lowering of pathogenic polyglutamine proteins靶向CAG的人工miRNA，以降低脱靶风险，高效降低致病性多谷氨酰胺蛋白
Pewinska-Kolodziejczak, Marianna; Kotowska-Zimmer, Anna; Przybyl, Lukasz; Wronka, Dorota; Karlik, Anna; Smuszkiewicz, Michal; Balcerek, Julia; Suszynska-Zajczyk, Joanna; Piaszyk-Borychowska, Anna; Urbanek-Trzeciak, Martyna; Sablok, Gaurav; Kozlowska, Emilia; Podkowinski, Jan; Fiszer, Agnieszka; Kozlowski, Piotr; Handschuh, Luiza; Olejniczak, Marta.png)
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收藏 Integrating transcriptomics and proteomics to assess antisense oligonucleotide safety and efficacy: a time-resolved approach整合转录组学和蛋白质组学评估反义寡核苷酸安全性和有效性：一种时间分辨方法van Leeuwen, Daniel; Cipullo, Miriam; Williams, Eleanor C.; Iannetta, Anthony; Chu, Britney; Wang, Junmin; Hamza, Ghaith; Crysnanto, Danang; Guzzi, Nicola; Tan, Jennifer Y.; Miele, Eric; Sawarkar, Ritwick; Mohorianu, Irina; Prill, Sebastian; Andersson, Patrik 分享 收藏 An integrated computational antigen discovery pipeline with hierarchical filtering for emerging viral variants针对新兴病毒变种的集成计算抗原发现流程及分层过滤方法Roy, Raj S.; Oh, Jaemin; Abeer, A. N. M. Nafiz; Giraldo, Maria, I; Ikegami, Tesuro; Weaver, Scott C.; Vasilakis, Nikolaos; Yoon, Byung-Jun; Qian, Xiaoning 分享 收藏 Genomic instability and mono-parental expression mitigate genomic shock in a cross-subgenus Leishmania hybrid基因组不稳定性与单亲表达减轻亚属间利什曼原虫杂交中的基因组冲击Louzada-Flores, Viviane Noll; Cokelaer, Thomas; Fuentes-Carias, Marcela; Pescher, Pascale; Ferreira, Tiago Rodrigues; Latrofa, Maria Stefania; Mendoza-Roldan, Jairo Alfonso; Otranto, Domenico; Spath, Gerald F.; Louradour, Isabelle 分享 收藏 Integrating transcriptomics and proteomics to assess antisense oligonucleotide safety and efficacy: a time-resolved approach (Vol 3, ugag016, 2026)整合转录组学和蛋白质组学评估反义寡核苷酸的安全性和有效性：一种时间分辨方法（第3卷，ugag016，2026）Leeuwen, Daniel van; Cipullo, Miriam; Williams, Eleanor C.; Iannetta, Anthony; Chu, Britney; Wang, Junmin; Hamza, Ghaith; Crysnanto, Danang; Guzzi, Nicola; Tan, Jennifer Y.; Miele, Eric; Sawarkar, Ritwick; Mohorianu, Irina; Prill, Sebastian; Andersson, Patrik 分享 收藏 Defective plasticity in dermatomyositis patients muscle stem cells is associated with sustained intrinsic inflammatory signaling and disruption of the histone H3.3 chromatin loading pathway皮肌炎患者肌肉干细胞中的缺陷可塑性与其持续性内源性炎症信号传导及组蛋白H3.3染色质加载途径的破坏有关Bouchereau, Wilhelm; Chenane, Linda; Weiss-Gayet, Michele; Lessard, Lola; Cardona, Yseult; Mounier, Remi; Gallay, Laure; Allenbach, Yves; Benveniste, Olivier; Corpet, Armelle; Chazaud, Benedicte; Lomonte, Patrick 分享 收藏 EBV genome analysis in multiple sclerosis shows extensive viral diversity and links to autoimmunityEBV基因组分析在多发性硬化中显示出广泛的病毒多样性并与自身免疫相关Lehikoinen, Joonas; Hannolainen, Leo; Rautila, Osma S.; Dickson, Zachery W.; Pyoria, Lari; Dieterich, Liane; Jansson, Lilja; Tammi, Silja; Hedman, Klaus; Perdomo, Maria F.; Tienari, Pentti J. 分享 收藏 Tetrahedral DNA nanostructure-delivered suppressor tRNA ameliorates nephropathy in COL4A5 nonsense mutation-mediated Alport syndrome mice四面体DNA纳米结构递送的抑制性tRNA改善了COL4A5无义突变介导的Alport综合征小鼠的肾病Lv, Jingru; Li, Ying; Hong, Dean; Shen, Yuxuan; Mi, Zeyuan; Liang, Qing; Zheng, Zhetao; Kong, Bangyan; Gao, Wankai; Dou, Zhiyang; Tian, Songlin; Xia, Qing 分享 收藏 
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