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Bioorganic Chemistry 封面图

Bioorganic Chemistry

IF4.7
论文数2254
被引数24853
期刊论文 2254
发表时间
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Magnolol protects against cisplatin-induced ototoxicity by reducing oxidative stress through PPAR-γ厚朴酚通过PPAR-γ减少氧化应激来保护顺铂诱导的耳毒性
deleteBioorganic Chemistry
IF4.7
delete2026-10-27
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PREAI
deleteZiyi Tang; Rui Luo; Chunyan Wang; Jian Zhou; Hongtao Ye; Yijun Li; Xia Gou; Juhong Zhang; Wei Yuan
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Development of a near-infrared two-photon fluorescent probe for highly sensitivity cysteine detection in Parkinson's disease via an electronic regulation strategy基于电子调控策略开发一种用于帕金森病中高灵敏度半胱氨酸检测的近红外双光子荧光探针
deleteBioorganic Chemistry
IF4.7
delete2026-10-26
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PREAI
deleteYuting Du; Hongliang Wang; Minmin Guo; Sanhu Zhao; Haixian Ren; Ting Zhang
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A biotinylated aloe emodin-based anthraquinone bioconjugate with enhanced cellular uptake and photodynamic activity一种基于生物素化芦荟大黄素的蒽醌生物缀合物，具有增强的细胞摄取和光动力活性
deleteBioorganic Chemistry
IF4.7
delete2026-10-26
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PREAI
deletePaula S. Rivero-Jerez; Daniel Zúñiga-Núñez; Joaquín Fernández-Martínez; Germán Gunther; Juliana Marioni; Susana C. Nuñez Montoya; Denis Fuentealba
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C-4-functionalized cyclogeraniols from saffron: Structural diversity, Enantiomerism, and stereochemistry-dependent anti-melanogenic activity从藏红花中获得的C-4-官能化环香叶醇：结构多样性、对映异构现象以及立体化学依赖的抗黑色素生成活性
deleteBioorganic Chemistry
IF4.7
delete2026-10-25
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PREAI
deleteTing-Ting Li; Si-Bo Ji; Si-Qi Ma; Han-Qi Zhang; Bai-Xiang Cai; Muaitaer Nuermaimaiti; Ju-Tao Wang; Guo-Kai Wang; Yang Yu
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A tetrahydroxanthylium-thiophene-triphenylamine based photosensitizer targeting mitochondrial DNA G-quadruplexes for overcoming cisplatin-resistant lung Cancer via white light photodynamic therapy四羟基芘并咪唑-噻吩-三苯胺基基团为基础的光敏剂靶向线粒体DNA G-四链体以通过白光光动力疗法克服顺铂耐药性肺癌
deleteBioorganic Chemistry
IF4.7
delete2026-10-25
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PREAI
deleteGan Li; Ming-Hao Hu
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Structure-guided identification and functional evaluation of small-molecule candidates predicted to target the LAG-3/MHC-II interface基于结构的靶向LAG-3/MHC-II界面小分子候选物的识别与功能评估
deleteBioorganic Chemistry
IF4.7
delete2026-10-24
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PREAI
deleteKe Ren; Pengshan Li; Jiacheng Liu; Eyad Elkord
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Ligulaplenolides A–S, nineteen undescribed eremophilane-type sesquiterpenoids from Ligularia platyglossa and their anti-inflammatory activity舌叶千里光内酯A–S，十九种未描述的千里光烷型倍半萜及其抗炎活性
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IF4.7
delete2026-10-24
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PREAI
deleteXiao-Song Zhu; Qiong Wang; Tian-Rong Yang; Tao Fu; Wen-Jing Pan; Guo-Tai Yang; Hao Chen; Hang Sun; Li-Hua Su; Min Xu
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Antibacterial activity and mechanistic insights into para-substituted triphenylphosphonium salts对位取代三苯基膦盐的抗菌活性及其机制研究
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IF4.7
delete2026-10-24
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deleteBárbara Nunes; Fernando Cagide; Anna C. Vetter; Hazel L.S. Fuchs; Fangfang Chen; Carlos Fernandes; Thekla Cordes; Fernanda Borges; Mark Brönstrup; Manuel Simões
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Development of cinnamyl derivatives as antibiotic-potentiating agents肉桂基衍生物作为抗生素增效剂的研发
deleteBioorganic Chemistry
IF4.7
delete2026-10-23
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deleteOAAI
deleteMichaela Hympanova; Martin Kufa; Lubica Muckova; Lukas Prchal; Jiri Janousek; Vladimir Finger; Ondrej Kovar; Jana Cizkova; Johannes Jagob; Anna Mansfeldova; Jan Marek; Ondrej Soukup; Jaroslav Roh; Jan Korabecny
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Discovery of novel pyridine-2-tetrazole derivatives as in vivo memory enhancement agents新型吡啶-2-四唑衍生物作为体内记忆增强剂
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IF4.7
delete2026-10-23
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PREAI
deleteNguyen Viet Hung; Van-Hai Hoang; Le Thien Bao Long; Vu Ngoc Hai Linh; Le Quoc Tien; Tran Vu Thuy Linh; Le Thi Tam Bang; Tiep K. Nguyen; Hang Thi Nguyet Pham; Dinh Thi Minh; Tran Thi Thu Hien; Shuai Wang; Phuong-Thao Tran
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Design, synthesis, antibacterial activity, and mechanistic studies of Ebselen derivatives against methicillin-resistant Staphylococcus aureusEbselen衍生物的设计、合成及其对耐甲氧西林金黄色葡萄球菌的抗菌活性和机制研究
deleteBioorganic Chemistry
IF4.7
delete2026-10-22
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PREAI
deleteYunjun Chen; Xiao-Wen Wu; Shi-Yi Liu; Junfeng Zhang; Cai-Ling Yang; Xu-Liang Xu; Gang-Ao Hu; Hong Wang; Bin Wei; Wei Hou
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Chlorogenic acid attenuates ovarian inflammation and oxidative stress and is associated with NF-κB/NLRP3-related molecular changes in PCOS rats: An integrated in vivo and in silico study绿原酸减轻卵巢炎症和氧化应激，并与PCOS大鼠NF-κB/NLRP3相关分子变化相关：一项整合体内和体外研究
deleteBioorganic Chemistry
IF4.7
delete2026-10-22
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PREAI
deleteSeyyedeh Fahimeh Talebi; Hamed Shoorei; Ramji Kumar Bhandari; Gholam Hossein Farjah; Tohid Rezaei Topraghaleh; Neda Abedpour
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Benzodiazepine-based N,S-heterocyclic hybrids as multi-target therapeutic candidates for cancer and inflammation: enzymatic evaluation, cellular mechanistic studies, in vivo anti-inflammatory assessment, and computational investigations苯二氮䓬类N,S-杂环杂合体作为癌症和炎症的多靶点治疗候选药物：酶学评价、细胞机制研究、体内抗炎评估和计算研究
deleteBioorganic Chemistry
IF4.7
delete2026-10-21
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PREAI
deleteHagar S. El-Hema; Marwa A. Abed; Mohamed A. Hawata; Eman S. Nossier; Abeer Salama; Modather F. Hussein; Ahmed T. Elhendawy; Heba A. El-Sayed; Adel A.-H. Abdel-Rahman
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Novel NIR DDNP-type solvatochromic and fluorogenic probes for amyloid β detection新型NIR DDNP型溶致变色和荧光探针用于检测淀粉样β蛋白
deleteBioorganic Chemistry
IF4.7
delete2026-10-21
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deleteMatic Rogan; Lana Blinc; Luka Rejc; Bruno Aleksander Martek; Uroš Vezonik; Ines Babnik; Blagoj Mukaetov; Ana Brodnik Rajković; Anže Meden; Johannes Pfabe; Marjan Slak Rupnik; Matej Jaklin; Mara Bresjanac; Stanislav Gobec; Damijan Knez; Jerneja Kladnik; Janez Košmrlj
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Corrigendum to “Unlocking the catalytic potential of transaminase: A two-decade evolution toward green and scalable biocatalysis” [Bioorg. Chem. 17 (2026) 109545]勘误表：“解锁转氨酶的催化潜力：二十年来迈向绿色和可扩展生物催化的演变” [Bioorg. Chem. 17 (2026) 109545]
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IF4.7
delete2026-10-21
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PREAI
deletePriyanka Mundhe; Pooja Sahu; Anitta Martin; P. Madhumitha; Meenu Kumari; Priyanka Bajaj
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Development of a photocaged CLIPTAC for spatiotemporal control of protein degradation光笼化的CLIPTAC的开发用于蛋白质降解的空间-时间控制
deleteBioorganic Chemistry
IF4.7
delete2026-10-21
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PREAI
deleteJaeseok Lee; Junhyeong Yim; Solbi Kim; Soyoung Yoon; Junyoung Park; Sihyeong Yi; Sunbin Jung; Ala Jo; Hankum Park; Jongmin Park
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Discovery and optimization of N-phenylbenzenesulfonamide analogues as novel ALKBH5 inhibitors for AML therapy发现和优化N-苯基苯磺酰胺类似物作为急性髓系白血病治疗的新型ALKBH5抑制剂
deleteBioorganic Chemistry
IF4.7
delete2026-10-20
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PREAI
deleteQiuting Xu; Shuying Xie; Jiachen Wei; Qinkuai Wu; Meng Xiao; Yike Ma; Hailang Xu; Wenxiu Wang; Xicheng Chen; Xiaoke Gu; Mingshan Niu; Jingying Qiu
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Modulation of strain-selective antimicrobial activity by the supramolecular ensemble of a pillar[5]arene with a protease柱[5]芳烃与蛋白酶的超分子组装体对菌株选择性抗菌活性的调控
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IF4.7
delete2026-10-20
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PREAI
deleteVildan Sultanaev; Anastasia Nazarova; Igor Sedov; Luidmila Yakimova; Timur Mukhametzyanov; Anastasiia Sapunova; Alexandra Voloshina; Dzmitry Shcharbin; Ivan Stoikov
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Design, synthesis, and pharmacological evaluation of 7-substituted 1,2,4-triazolo[1,5-a]pyrimidine derivatives as novel antiepileptic lead candidates targeting Nav1.2 channels7-取代的1,2,4-三唑并[1,5-a]嘧啶衍生物的设计、合成及药理学评价：作为靶向Nav1.2通道的新型抗癫痫先导候选物
deleteBioorganic Chemistry
IF4.7
delete2026-10-18
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PREAI
deleteLuqian He; Qiaoliang Zhang; Wenjuan Ma; Meiqi Qian; Yifan Dong; Feifei Xin; Chuanlong Guo; Guorui Cao; Fang Tuo; Longjiang Huang
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A synergistic platform integrating iodinated BODIPY photosensitizers and microglial cells for superior photodynamic antibacterial efficacy一种整合碘化BODIPY光敏剂和小胶质细胞的协同平台，用于实现卓越的光动力抗菌效能
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IF4.7
delete2026-10-17
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PREAI
deleteMingmin Gu; Jian Li; Bo Liu; Nan Yang; Maoran Lang; Yali Han; Bo Kou; Ping Yang; Wenzheng Ding; Wenhai Lin; Songqing Zhu; Qiang Tong; Li Quan
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